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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

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Composition :

INDINAVIR-400MG

Manufacturer/Marketer :

Emcure Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Inbec 400 Capsule

Inbec 400 Capsule belongs to a group of antiretroviral medicines indicated for the treatment of HIV infection. Inbec 400 Capsule does not cure HIV infection. It reduces the viral load in the body and keeps it at a low level. Taking Inbec 400 Capsule decreases the chance of developing AIDS (acquired immunodeficiency syndrome) and HIV-related illnesses such as cancer or serious infections.
 
Inbec 400 Capsule contains Indinavir, which works by decreasing the amount of HIV in the blood. It also increases the count of CD4 (T) cells, a type of white blood cell that helps the body fight infection.
 
In some cases, Inbec 400 Capsule may cause side effects such as nausea, headache, loss of appetite, and weakness. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to the doctor if the side effects persist or worsen.
 
Consult the doctor if you are pregnant or planning for pregnancy. Avoid breastfeeding whilst on treatment with Inbec 400 Capsule. Tell the doctor about your new or worsening symptoms during treatment with Inbec 400 Capsule. Keep your doctor informed about your health condition and medications to prevent any side effects/interactions.

Uses of Inbec 400 Capsule

HIV infection

Directions for Use

Swallow Inbec 400 Capsule as a whole with water or other beverages such as skim or non-fat milk, juice, coffee, or tea; do not chew or crush it. Take Inbec 400 Capsule on an empty stomach, i.e., 1 hour before or 2 hours after meals. If you experience stomach upset, take it with a light meal such as cornflakes or dry toast.

Medicinal Benefits

Inbec 400 Capsule belongs to a group of antiretroviral medicines called protease inhibitors used to treat HIV infection. Inbec 400 Capsule contains Indinavir, which works by decreasing the amount of HIV in the blood. It also increases the count of CD4 (T) cells, a type of white blood cell that helps the body fight infection. Inbec 400 Capsule reduces the viral load in the body and keeps it at a low level. Taking Inbec 400 Capsule decreases the chance of developing AIDS (acquired immunodeficiency syndrome) and HIV-related illnesses such as cancer or serious infections. Inbec 400 Capsule may also be used in combination with other medicines to treat people exposed to HIV infection after accidental contact with HIV-contaminated blood, body fluids, or tissues.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Inbec 400 Capsule if you are allergic to any of its components. Inform your doctor if you have liver problems, especially if you have mild/moderate liver disease caused by cirrhosis, kidney problems, diabetes, haemophilia (a disorder in which the blood does not clot properly), high cholesterol and if you are taking cholesterol-lowering medicines known as statins. Let the doctor know if you are taking prescription/non-prescription medicines, including herbal products or dietary supplements.

Drug-Drug Interactions

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DolutegravirDofetilide
Critical
LamivudineEmtricitabine
Critical

Drug-Drug Interactions

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DolutegravirDofetilide
Critical
How does the drug interact with Inbec 400 Capsule:
Taking Inbec 400 Capsule with dofetilide may possibly reduce the blood levels and effects of Inbec 400 Capsule. This can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although taking Inbec 400 Capsule with Dofetilide is not recommended, they can be taken together if prescribed by a doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, or irregular heartbeat. Do not stop taking any medications without consulting a doctor.
LamivudineEmtricitabine
Critical
How does the drug interact with Inbec 400 Capsule:
Combining these two medications may reduce overall effectiveness due to potential antagonistic effects (opposite actions).

How to manage the interaction:
Taking Emtricitabine with Inbec 400 Capsule is not recommended, but it can be taken if your doctor prescribes it. Contact your doctor if your symptoms do not improve. Do not stop taking any medication without consulting your doctor.
How does the drug interact with Inbec 400 Capsule:
Co-administration of Inbec 400 Capsule with calcium acetate can reduce the effectiveness of Inbec 400 Capsule.

How to manage the interaction:
Taking Inbec 400 Capsule with calcium acetate together can possibly result in an interaction, they can be taken together if prescribed by your doctor. It is recommended to take Inbec 400 Capsule at least two hours before or six hours after the calcium acetate dose. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Inbec 400 Capsule:
Taking Inbec 400 Capsule with nevirapine can reduce the effectiveness of Inbec 400 Capsule.

How to manage the interaction:
Although taking Inbec 400 Capsule and Nevirapine together can possibly result in an interaction, they can be taken together if prescribed by your doctor. Do not discontinue using any medications without consulting a doctor.
DolutegravirFerric maltol
Severe
How does the drug interact with Inbec 400 Capsule:
Taking Inbec 400 Capsule with ferric maltol can reduce the effectiveness of Inbec 400 Capsule.

How to manage the interaction:
Although taking Inbec 400 Capsule and Ferric maltol together can possibly result in an interaction, they can be taken together if prescribed by your doctor. It is advised to take Inbec 400 Capsule either two hours before or six hours after taking a dose of Ferric maltol. Do not discontinue using any medications without consulting a doctor.
DolutegravirEtravirine
Severe
How does the drug interact with Inbec 400 Capsule:
Taking Inbec 400 Capsule with etravirine can reduce the blood levels and effectiveness of Inbec 400 Capsule.

How to manage the interaction:
Although taking Inbec 400 Capsule and Etravirine together can possibly result in an interaction, they can be taken together if prescribed by your doctor. Do not discontinue using any medications without consulting a doctor.
How does the drug interact with Inbec 400 Capsule:
Phenobarbital may significantly decrease Inbec 400 Capsule blood levels, making the medicine less effective.

How to manage the interaction:
Although taking Inbec 400 Capsule and Phenobarbital together can result in an interaction, they can be taken together if prescribed by a doctor. Do not discontinue using any medications without consulting a doctor.
How does the drug interact with Inbec 400 Capsule:
Co-administration of Inbec 400 Capsule with Calcium carbonate can reduce the effectiveness of Inbec 400 Capsule.

How to manage the interaction:
Although there is an interaction, calcium carbonate can be taken with Inbec 400 Capsule if prescribed by the doctor. However, Inbec 400 Capsule and calcium carbonate should not be taken orally at the same time. Maintain a gap of 2-6 hours between both medicines. Do not discontinue using any medications without consulting a doctor.
DolutegravirDidanosine
Severe
How does the drug interact with Inbec 400 Capsule:
Co-administration of Inbec 400 Capsule with Didanosine can reduce the effectiveness of Inbec 400 Capsule.

How to manage the interaction:
Although taking Inbec 400 Capsule and Didanosine together can possibly result in an interaction, they can be taken together if prescribed by your doctor. It is recommended to take Inbec 400 Capsule at least two hours before or six hours after the didanosine dose. Do not discontinue using any medications without consulting a doctor.
How does the drug interact with Inbec 400 Capsule:
Taking Inbec 400 Capsule with magnesium oxide can reduce the effectiveness of Inbec 400 Capsule.

How to manage the interaction:
Taking Magnesium oxide with Inbec 400 Capsule together can result in an interaction, it can be taken if your doctor has advised it. However, take Inbec 400 Capsule at least two hours before or six hours after the magnesium oxide dose. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Practise safe sex by using condoms; it helps in reducing contact with semen and vaginal fluids.
  • Never share personal items that can have body fluids or blood on them, such as razor blades or toothbrushes.
  • Avoid sharing used needles, other injections or drug equipment.
  • Eat a healthy and balanced diet. Eat vitamin and nutrient-rich food such as vegetables and fruits as it helps to boost your immune system. Opt for lean protein and whole grains.
  • Avoid eating raw meat and eggs. Consume properly boiled and cooked meat, poultry or seafood.
  • Eat bland and low-fat foods, and avoid spicy or oily foods if you experience nausea or vomiting.
  • Try to reduce emotional and physical stress by spending time with family or doing whatever makes you happy.

Habit Forming

No

Therapeutic Class

ANTIRETROVIRAL AGENTS

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Inbec 400 Capsule works by decreasing the amount of HIV in the blood. Thereby, Inbec 400 Capsule helps treat HIV infection.

Taking Inbec 400 Capsule with cholesterol-lowering medicines called statins may cause severe muscle pain and weakness. Consult the doctor if you experience severe muscle pain or weakness.

Inbec 400 Capsule may cause kidney stones. Therefore, drink plenty of fluids while on treatment with Inbec 400 Capsule as it helps reduce the chances of forming a kidney stone. Consult the doctor if you develop kidney pain (middle to the lower stomach or back pain) or blood in the urine.

Inbec 400 Capsule does not reduce the risk of passing HIV to others through blood contamination or sexual contact. Therefore, practice safe sex to prevent the risk of transmission.

Consult the doctor before taking sildenafil, tadalafil, or vardenafil with Inbec 400 Capsule as taking them together might increase the risk of side effects like low blood pressure, penile erection lasting more than 4 hours, or visual changes associated with sildenafil, tadalafil, and vardenafil. Seek immediate medical assistance if you have an erection lasting longer than 4 hours.

Didanosine can be taken with Inbec 400 Capsule if prescribed by the doctor. However, maintain a gap of 1 hour between didanosine and Inbec 400 Capsule.

Inbec 400 Capsule may cause hyperglycaemia (high blood sugar) even though you do not have diabetes. Consult the doctor immediately if you notice symptoms of high blood sugar, like frequent urination, extreme thirst, blurred vision, extreme hunger, or weakness. High blood sugar can lead to a serious condition called ketoacidosis if not treated. Symptoms of ketoacidosis include nausea, vomiting, dry mouth, shortness of breath, and decreased consciousness.

Drug-Drug Interactions Checker List

  • MIDAZOLAM
  • TRIAZOLAM
  • ALPRAZOLAM
  • PIMOZIDE
  • CISAPRIDE
  • AMIODARONE
  • ASTEMIZOLE
  • SILDENAFIL
  • ALFUZOSIN
  • RIFAMPIN
  • LOVASTATIN
  • SIMVASTATIN
  • ROSUVASTATIN
  • ATORVASTATIN
  • ATAZANAVIR
  • St John's wort

Special Advise

  • Avoid taking Inbec 400 Capsule at the same time as meals that are high in calories, protein, or fat.
  • Drink at least 1.5 litres of fluids (preferably water) throughout the day, every day. 

Disease/Condition Glossary

HIV infection: HIV (Human Immunodeficiency Virus) is a virus that attacks the immune system and destroys the white blood cells that help fight infection, making the individual susceptible to other infections or illnesses. People with HIV experience flu-like symptoms such as fever, chills, rash, night sweats, muscle aches, tiredness, and sore throat. These symptoms usually last for days to several weeks. It spreads through body fluids such as semen, vaginal fluid, and blood. If left untreated, this condition can lead to AIDS (Acquired Immunodeficiency Syndrome). It is a life-long condition, and there is no definite cure for it. However, it can be controlled by treating it with antiretroviral drugs. 

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