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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

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Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About Isavufic 200 mg Injection 1's

Isavufic 200 mg Injection 1's belongs to the class of medicines called antifungals used to treat fungal infections such as invasive aspergillosis and mucormycosis (in patients for whom Amphotericin B is not suitable). Invasive aspergillosis is an infection caused by Aspergillus fungus. It occurs by breathing and spreads from the lungs to the kidneys, brain, heart or skin. Mucormycosis is a rare but serious fungal infection of the skin or respiratory system that occurs in people with weakened immune systems.

Isavufic 200 mg Injection 1's contains Isavuconazole which works by fungicidal actions by disrupting the biosynthesis of ergosterol,which are essential for their survival and kills fungus that causes infection.

Isavufic 200 mg Injection 1's will be administered by a healthcare professional; do not self-administer. Some people may experience headache, decreased appetite, sleepiness, nausea, vomiting, stomach pain, diarrhoea or chest pain. Most of these side effects of Isavufic 200 mg Injection 1's do not require medical attention and gradually resolve over time. However, if the side effects worsen or persist, please consult your doctor.

If you are allergic to Isavufic 200 mg Injection 1's or any other medicines, please tell your doctor. Isavufic 200 mg Injection 1's is not recommended for children below 18 years as the safety and effectiveness were not established. If you are pregnant, it is advised to consult a doctor before using Isavufic 200 mg Injection 1's. Avoid breastfeeding while taking Isavufic 200 mg Injection 1's. Drive only if you are alert after taking Isavufic 200 mg Injection 1's as it may cause drowsiness, confusion or dizziness. Avoid alcohol consumption while taking Isavufic 200 mg Injection 1's as it may increase the risk of liver damage.

Uses of Isavufic 200 mg Injection 1's

Invasive aspergillosis and Mucormycosis

Directions for Use

Isavufic 200 mg Injection 1's will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Isavufic 200 mg Injection 1's contains Isavuconazole, a broad-spectrum antifungal that is effective against a wide variety of microorganisms. It inhibits the synthesis of fungal cell membranes that are essential for their survival. Thereby, Isavufic 200 mg Injection 1's kills or stops the growth of the fungus.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Isavufic 200 mg Injection 1's

  • Headache
  • Decreased appetite
  • Sleepiness
  • Nausea
  • Vomiting
  • Stomach pain
  • Diarrhoea
  • Chest pain

Drug Warnings

If you are allergic to Isavufic 200 mg Injection 1's or any other medicines, please tell your doctor. Isavufic 200 mg Injection 1's is not recommended for children below 18 years as the safety and effectiveness were not established. If you are pregnant, it is advised to consult a doctor before using Isavufic 200 mg Injection 1's. Avoid breastfeeding while taking Isavufic 200 mg Injection 1's. Drive only if you are alert after taking Isavufic 200 mg Injection 1's as it may cause drowsiness, confusion or dizziness. Avoid alcohol consumption while taking Isavufic 200 mg Injection 1's as it may increase the risk of liver damage. If you experience severe blistering of the eyes, mouth, skin or genitals, seek immediate medical help.

Drug-Drug Interactions

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IsavuconazoleRitonavir
Critical
IsavuconazoleFosamprenavir
Critical

Drug-Drug Interactions

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IsavuconazoleRitonavir
Critical
How does the drug interact with Isavufic 200 mg Injection:
Taking Isavufic 200 mg Injection with Ritonavir may significantly increase the blood levels of Isavufic 200 mg Injection, which may increase the risk of side effects.

How to manage the interaction:
Taking Isavufic 200 mg Injection with Ritonavir is not recommended as it can possibly result in an interaction, it can be taken if a doctor has advised it. If you notice any of these symptoms like nausea, vomiting, loose stools, light color stools or dark urine, consult a doctor. Do not discontinue any medications without consulting a doctor.
IsavuconazoleFosamprenavir
Critical
How does the drug interact with Isavufic 200 mg Injection:
When Fosamprenavir is taken with Isavufic 200 mg Injection, it can increase the risk of side effects like liver damage.

How to manage the interaction:
Taking Isavufic 200 mg Injection with Fosamprenavir is not recommended, it can be taken if prescribed by the doctor. However, if you experience nausea, vomiting, diarrhea while on therapy with these drugs, consult the doctor.
IsavuconazoleKetoconazole
Critical
How does the drug interact with Isavufic 200 mg Injection:
Co-administration of Ketoconazole and Isavufic 200 mg Injection can significantly increase the blood levels of Isavufic 200 mg Injection, which may increase the risk of side effects.

How to manage the interaction:
Taking Isavufic 200 mg Injection with Ketoconazole is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. However, if you experience symptoms like nausea, stomach pain, headache while on therapy with these drugs, consult the doctor. Do not discontinue any medication without consulting a doctor.
IsavuconazoleClarithromycin
Critical
How does the drug interact with Isavufic 200 mg Injection:
When Isavufic 200 mg Injection is taken with Clarithromycin, it can increase the risk of side effects.

How to manage the interaction:
Co-administration of Clarithromycin and Isavufic 200 mg Injection can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like nausea, vomiting, or diarrhoea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
IsavuconazoleItraconazole
Critical
How does the drug interact with Isavufic 200 mg Injection:
The blood levels and effects of Isavufic 200 mg Injection may be significantly enhanced by taking Itraconazole along with it.

How to manage the interaction:
Co-administration of Isavufic 200 mg Injection and Itraconazole can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like nausea, vomiting, or diarrhoea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
IsavuconazoleSaquinavir
Critical
How does the drug interact with Isavufic 200 mg Injection:
When Isavufic 200 mg Injection is taken with Saquinavir, it can increase the risk of liver damage.

How to manage the interaction:
Taking Isavufic 200 mg Injection with Saquinavir is not recommended, it can be taken if prescribed by the doctor. However, if you experience symptoms like nausea, vomiting, diarrhea while on therapy with these drugs, consult the doctor.
IsavuconazolePosaconazole
Critical
How does the drug interact with Isavufic 200 mg Injection:
When Isavufic 200 mg Injection is taken with Posaconazole, it can increase the levels of Isavufic 200 mg Injection in the blood.

How to manage the interaction:
Although there is an interaction between Isavufic 200 mg Injection and posaconazole, it can be taken if prescribed by the doctor. However, if you experience nausea, vomiting, diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
IsavuconazoleCarbamazepine
Critical
How does the drug interact with Isavufic 200 mg Injection:
When Carbamazepine and Isavufic 200 mg Injection are taken together, carbamazepine will reduce the effectiveness of the Isavufic 200 mg Injection.

How to manage the interaction:
Taking Isavufic 200 mg Injection with Carbamazepine is not recommended, it can be taken if prescribed by the doctor. Do not discontinue any medications without doctor's advice.
IsavuconazolePhenytoin
Critical
How does the drug interact with Isavufic 200 mg Injection:
Co-administration of phenytoin and Isavufic 200 mg Injection may significantly reduce the blood levels of Isavufic 200 mg Injection, which may make Isavufic 200 mg Injection less effective in treating your condition.

How to manage the interaction:
Taking Isavufic 200 mg Injection with Phenytoin is not recommended as it can cause an interaction, consult a doctor before taking it. Do not discontinue any medication without consulting a doctor.
IsavuconazoleCisapride
Critical
How does the drug interact with Isavufic 200 mg Injection:
When Isavufic 200 mg Injection is taken with Cisapride, it can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Isavufic 200 mg Injection with Cisapride is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Try to avoid areas with a lot of dust like excavation or construction sites. If you can’t avoid it, wear an N95 mask while going to such places.
  • Clean skin injuries with soap and water, especially if they have been exposed to dust or soil to decrease the chances of developing a skin infection.
  • Bandage all wounds until they heal to prevent fungal infections.
  • Wash your hands frequently and keep your hands clean to prevent the spread of germs.
  • Avoid dusty activities and digging in the soil.
  • Wear shoes, a long-sleeved t-shirt, long pants and a mask while doing outdoor activities such as yard work, gardening or vising wooded areas to protect from fungus commonly present in the environment.
  • Maintain a diet that is low in sugar, refined carbohydrates, mould-containing foods and yeast.

Habit Forming

No

Therapeutic Class

ANTIFUNGALS

Isavufic 200 mg Injection 1's Substitute

Substitutes safety advice
  • Cresemba 200Mg Injection

    by AYUR

    9264.40per tablet
  • Isuvaz 200 mg Infusion 1's

    by Others

    10783.00per tablet

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • RITONAVIR
  • EFAVIRENZ
  • ETRAVIRINE
  • RIFABUTIN
  • RIFAMPICIN
  • PREDNISONE
  • TACROLIMUS
  • SIROLIMUS
  • CICLOSPORIN
  • PIOGLITAZONE
  • CARBAMAZEPINE
  • PHENOBARBITAL
  • PHENYTOIN
  • KETOCONAZOLE
  • METFORMIN

Special Advise

Regular blood tests are recommended while taking Isavufic 200 mg Injection 1's to monitor liver functioning.

Disease/Condition Glossary

Invasive aspergillosis: It is an infection carried on by the fungus Aspergillus. When the infection moves from the lungs to the kidneys, brain, heart, or skin, it manifests itself. It mostly affects people whose immune systems have been compromised by chemotherapy or other illnesses like cancer or AIDS. The signs include coughing, fever, chest pain, and shortness of breath (sometimes with blood).

Mucormycosis: People with compromised immune systems are more susceptible to this uncommon but severe fungal infection of the skin or respiratory system. It can lead to death if not treated. Nasal congestion, headaches, coughs, fevers, and pain in the sinuses are some of the signs of respiratory infections. The signs of a skin infection include blisters or ulcers, redness, swelling, tenderness, and blackened skin tissue.

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