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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

Online payment accepted

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Composition :

MIDAZOLAM-1MG

Manufacturer/Marketer :

6Ipain Healthcare Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Isedaz Injection

Isedaz Injection belongs to a class of drugs called benzodiazepines (sedatives) used to induce sedation and relieve anxiety and muscle tension. It is used to induce sleepiness during therapeutic procedures (like endoscopy or colonoscopy) or complicated medical tests known as procedural sedation. Conscious sedation is a technique in which drugs help you relax (sedative), reduce anxiety and inhibit pain (anaesthetic) during a medical test or procedure. It is usually referred to as procedural sedation and analgesia.

Isedaz Injection contains Midazolam which works by increasing GABA activity (a chemical messenger in the brain that acts as a natural nerve-calming agent) involved in inducing drowsiness. Thereby, Isedaz Injection relaxes muscles, reduces anxiety and causes drowsiness.

Isedaz Injection will be administered by a healthcare professional; do not self-administer. Sometimes, it may cause side effects such as redness, pain or swelling at the injection site, headache, drowsiness, dizziness, confusion, dry mouth, tiredness or muscle spasms. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Midazolam or any other medicines, please tell your doctor. If you are pregnant or planning pregnancy, inform your doctor before taking Isedaz Injection. It may be excreted in breast milk. Therefore, avoid breastfeeding for 24 hours after taking Isedaz Injection. Isedaz Injection should be used with caution in elderly patients as there is an increased risk of breaking bones and falling. Special care should be taken while treating children with Isedaz Injection. Avoid consumption of alcohol while on treatment with Isedaz Injection as it may increase the sedative effect. Isedaz Injection may cause drowsiness or affect concentration and coordination. It is an offence to drive if Isedaz Injection affects you. Therefore, avoid driving if you feel drowsy after taking Isedaz Injection.

Uses of Isedaz Injection

Conscious sedation

Directions for Use

Isedaz Injection will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Isedaz Injection contains Midazolam used to induce conscious sedation (awake but very relaxed state of calm or drowsiness) during therapeutic procedures or medical tests. Isedaz Injection increases the activity of GABA (a chemical messenger in the brain that acts as a natural nerve-calming agent) that is involved in inducing drowsiness. Thereby, Isedaz Injection relaxes muscles, reduces anxiety and causes drowsiness.

Storage

Store in a cool and dry place away from sunlight
Side effects of Isedaz Injection 10 ml
  • Get plenty of fresh air.
  • Take regular sips of a cold drink.
  • Take ginger containing foods like ginger tea and ginger biscuits.
  • Do not take heavy meals at a time, take small and frequent meals.
  • Hiccups can be controlled if you can hold your breath for a short time.
  • Drink plenty of warm fluids and gargle with salt water.
  • Swallow some sugar as it can give relief to some extent.
  • You can try to pull your knees up to your chest and lean forward, which helps relieve hiccups.
  • Try to breathe in a paper bag for a while, but don't keep the paper over your head.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Get enough sleep. Maintain a regular sleep cycle.
  • Eat a healthy diet and exercise regularly.
  • Manage stress with yoga or meditation.
  • Limit alcohol and caffeine.
  • Avoid driving or operating machinery unless you are alert.
Managing Low Blood Pressure Triggered by Medication: Expert Advice:
  • If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
  • Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
  • As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
  • Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
  • Take regular breaks to sit or lie down if you need to stand for long periods.
  • When lying down, elevate your head with extra pillows to help improve blood flow.
  • Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
  • Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
  • If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.

Drug Warnings

If you are allergic to Midazolam or any other medicines, please inform your doctor. If you are pregnant or planning pregnancy, inform your doctor before taking Isedaz Injection. Isedaz Injection may be excreted in breast milk. Therefore, avoid breastfeeding for 24 hours after taking Isedaz Injection. Isedaz Injection should be used with caution in elderly patients as there is an increased risk of breaking bones and falling. Special care should be taken while giving Isedaz Injection to children, and the dose should be adjusted appropriately. Avoid consumption of alcohol with Isedaz Injection as it may increase the sedative effect of Isedaz Injection. Isedaz Injection may cause drowsiness or affect concentration and coordination. It is an offence to drive if Isedaz Injection affects you. Therefore, avoid driving if you feel drowsy after taking Isedaz Injection. Do not take Isedaz Injection with opioids as it may increase the risk of difficulties in breathing, drowsiness or coma. However, if the concomitant use is advised by a doctor, the dose and duration should be limited by a doctor.

Drug-Drug Interactions

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MidazolamDelavirdine
Critical

Drug-Drug Interactions

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How does the drug interact with Isedaz Injection 10 ml:
Co-administration of Mifepristone and Isedaz Injection 10 ml may significantly increase Isedaz Injection 10 ml blood levels and effects, which increases the risk of side effects.

How to manage the interaction:
Although taking Mifepristone and Isedaz Injection 10 ml together may result in an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have excessive or prolonged sleepiness and breathing issues. Do not discontinue any medication without consulting a doctor.
MidazolamDelavirdine
Critical
How does the drug interact with Isedaz Injection 10 ml:
The negative effects of Isedaz Injection 10 ml and Delavirdine might be increased when used together.

How to manage the interaction:
Taking Isedaz Injection 10 ml together Delavirdine may cause an interaction. They can, however, be taken if a doctor has prescribed them. Consult a doctor if you have any of the following symptoms: excessive sleepiness, dizziness, confusion, or weak or rapid breathing. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Isedaz Injection 10 ml:
Atazanavir and Isedaz Injection 10 ml co-administration may considerably enhance Isedaz Injection 10 ml blood levels and effects.

How to manage the interaction:
Although taking Atazanavir and Isedaz Injection 10 ml together may result in an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have excessive or prolonged sleepiness and breathing issues. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Isedaz Injection 10 ml:
Indinavir and Isedaz Injection 10 ml co-administration may considerably enhance Isedaz Injection 10 ml blood levels and effects.

How to manage the interaction:
Although taking Indinavir and Isedaz Injection 10 ml together may result in an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have excessive or prolonged sleepiness and breathing issues. Do not discontinue any medication without consulting a doctor.
MidazolamCobicistat
Critical
How does the drug interact with Isedaz Injection 10 ml:
Cobicistat and Isedaz Injection 10 ml co-administration may considerably enhance Isedaz Injection 10 ml blood levels and effects.

How to manage the interaction:
Although taking Cobicistat and Isedaz Injection 10 ml together may result in an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have excessive or prolonged sleepiness and breathing issues. Do not discontinue any medication without consulting a doctor.
MidazolamSodium oxybate
Critical
How does the drug interact with Isedaz Injection 10 ml:
Sodium oxybate and Isedaz Injection 10 ml co-administration may considerably enhance Isedaz Injection 10 ml blood levels and effects.

How to manage the interaction:
Although taking Sodium oxybate and Isedaz Injection 10 ml together may result in an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have excessive or prolonged sleepiness and breathing issues. Do not discontinue any medication without consulting a doctor.
MidazolamIdelalisib
Critical
How does the drug interact with Isedaz Injection 10 ml:
Idelalisib and Isedaz Injection 10 ml co-administration may considerably enhance Isedaz Injection 10 ml blood levels and effects.

How to manage the interaction:
Although taking Idelalisib and Isedaz Injection 10 ml together may result in an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have excessive or prolonged sleepiness and breathing issues. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Isedaz Injection 10 ml:
Co-administration of Ketoconazole and Isedaz Injection 10 ml may increase the risk of side effects.

How to manage the interaction:
Although taking Ketoconazole and Isedaz Injection 10 ml together is not recommended as it may result in an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have excessive or prolonged sleepiness and breathing issues. Do not discontinue any medication without consulting a doctor.
MidazolamTelaprevir
Critical
How does the drug interact with Isedaz Injection 10 ml:
Telaprevir and Isedaz Injection 10 ml co-administration may considerably enhance Isedaz Injection 10 ml blood levels and effects.

How to manage the interaction:
Although taking Telaprevir and Isedaz Injection 10 ml together may result in an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have excessive or prolonged sleepiness and breathing issues. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Isedaz Injection 10 ml:
Taking ceritinib and Isedaz Injection 10 ml may significantly increase the blood levels and effects of Isedaz Injection 10 ml.

How to manage the interaction:
Although taking ceritinib and Isedaz Injection 10 ml together may result in an interaction, they can be taken if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Habit Forming

Yes

Therapeutic Class

SEDATIVE-HYPNOTIC DRUGS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Isedaz Injection contains Midazolam which works by increasing the activity of GABA (a chemical messenger in the brain that acts as a natural nerve-calming agent) that is involved in inducing drowsiness. Thus, it relaxes muscles, reduces anxiety and causes drowsiness.

You are not recommended to take Isedaz Injection with opioids as co-administration of these medicines as it may increase the risk of adverse effects such as difficulties in breathing, drowsiness or coma. Therefore, before using Isedaz Injection with any other medicines, please consult your doctor so that the dosage may be adjusted accordingly to use safely.

Yes, Isedaz Injection may cause dizziness, drowsiness or affect concentration and coordination. Therefore, it is recommended to avoid driving or any other activities that require mental alertness after taking Isedaz Injection. Also, it is an offence to drive if Isedaz Injection affects your ability to drive.

Yes, Isedaz Injection may cause physical dependence and withdrawal symptoms if used for prolonged periods. Therefore, do not stop treatment with Isedaz Injection suddenly. Your doctor will reduce the dose gradually to avoid withdrawal symptoms.

Isedaz Injection is not recommended for patients suffering from myasthenia gravis (severe muscle weakness) as it may worsen the condition. Therefore, inform your doctor if you have myasthenia gravis before taking Isedaz Injection.

Drug-Drug Interactions Checker List

  • DILTIAZEM
  • NIFEDIPINE
  • VERAPAMIL
  • FLUCONAZOLE
  • KETOCONAZOLE
  • VORICONAZOLE
  • ITRACONAZOLE
  • POSACONAZOLE
  • CLARITHROMYCIN
  • ERYTHROMYCIN
  • ROXITHROMYCIN
  • RIFAMPICIN
  • ATORVASTATIN
  • SAQUINAVIR
  • PHENYTOIN
  • CARBAMAZEPINE
  • FENTANYL
  • DIAZEPAM

Special Advise

If you receive Isedaz Injection for prolonged periods, it may cause dependence and withdrawal symptoms. Therefore, do not stop taking Isedaz Injection suddenly. Your doctor will reduce the dose gradually to avoid withdrawal symptoms.

Disease/Condition Glossary

Conscious sedation: It is a technique in which drugs help you relax (sedative), reduce anxiety and inhibit pain (anaesthetic) during a medical test or procedure. You will stay awake but may not be able to speak. It is usually referred to as procedural sedation and analgesia.

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