Midfix 1 Injection 5 ml belongs to a class of drugs called benzodiazepines (sedatives) used to induce sedation and relieve anxiety and muscle tension. It is used to induce sleepiness during therapeutic procedures (like endoscopy or colonoscopy) or complicated medical tests known as procedural sedation. Conscious sedation is a technique in which drugs help you relax (sedative), reduce anxiety and inhibit pain (anaesthetic) during a medical test or procedure. It is usually referred to as procedural sedation and analgesia.

Midfix 1 Injection 5 ml contains Midazolam which works by increasing GABA activity (a chemical messenger in the brain that acts as a natural nerve-calming agent) involved in inducing drowsiness. Thereby, Midfix 1 Injection 5 ml relaxes muscles, reduces anxiety and causes drowsiness.

Midfix 1 Injection 5 ml will be administered by a healthcare professional; do not self-administer. Sometimes, it may cause side effects such as redness, pain or swelling at the injection site, headache, drowsiness, dizziness, confusion, dry mouth, tiredness or muscle spasms. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Midazolam or any other medicines, please tell your doctor. If you are pregnant or planning pregnancy, inform your doctor before taking Midfix 1 Injection 5 ml. It may be excreted in breast milk. Therefore, avoid breastfeeding for 24 hours after taking Midfix 1 Injection 5 ml. Midfix 1 Injection 5 ml should be used with caution in elderly patients as there is an increased risk of breaking bones and falling. Special care should be taken while treating children with Midfix 1 Injection 5 ml. Avoid consumption of alcohol while on treatment with Midfix 1 Injection 5 ml as it may increase the sedative effect. Midfix 1 Injection 5 ml may cause drowsiness or affect concentration and coordination. It is an offence to drive if Midfix 1 Injection 5 ml affects you. Therefore, avoid driving if you feel drowsy after taking Midfix 1 Injection 5 ml.

Midfix 1 Injection 5 ml contains Midazolam used to induce conscious sedation (awake but very relaxed state of calm or drowsiness) during therapeutic procedures or medical tests. Midfix 1 Injection 5 ml increases the activity of GABA (a chemical messenger in the brain that acts as a natural nerve-calming agent) that is involved in inducing drowsiness. Thereby, Midfix 1 Injection 5 ml relaxes muscles, reduces anxiety and causes drowsiness.

• Redness, pain or swelling at the injection site
• Headache
• Drowsiness
• Dizziness
• Confusion
• Dry mouth
• Tiredness
• Muscle spasms

If you are allergic to Midazolam or any other medicines, please inform your doctor. If you are pregnant or planning pregnancy, inform your doctor before taking Midfix 1 Injection 5 ml. Midfix 1 Injection 5 ml may be excreted in breast milk. Therefore, avoid breastfeeding for 24 hours after taking Midfix 1 Injection 5 ml. Midfix 1 Injection 5 ml should be used with caution in elderly patients as there is an increased risk of breaking bones and falling. Special care should be taken while giving Midfix 1 Injection 5 ml to children, and the dose should be adjusted appropriately. Avoid consumption of alcohol with Midfix 1 Injection 5 ml as it may increase the sedative effect of Midfix 1 Injection 5 ml. Midfix 1 Injection 5 ml may cause drowsiness or affect concentration and coordination. It is an offence to drive if Midfix 1 Injection 5 ml affects you. Therefore, avoid driving if you feel drowsy after taking Midfix 1 Injection 5 ml. Do not take Midfix 1 Injection 5 ml with opioids as it may increase the risk of difficulties in breathing, drowsiness or coma. However, if the concomitant use is advised by a doctor, the dose and duration should be limited by a doctor.

Drug-Drug Interaction: Inform your doctor if you are taking high blood pressure-lowering medicines (diltiazem, nifedipine, verapamil), antifungals (fluconazole, ketoconazole, voriconazole, itraconazole, posaconazole), antibiotics (clarithromycin, erythromycin, roxithromycin, rifampicin), high cholesterol-lowering medicines (atorvastatin), medicines for HIV/AIDS (saquinavir), anticonvulsants (phenytoin, carbamazepine), opioid pain killers (fentanyl), anti-allergic medicines, antianxiety drug (diazepam), antidepressants, and other medicines.

Drug-Food Interaction: Midfix 1 Injection 5 ml may interact with grapefruit. Therefore, avoid intake of grapefruit or grapefruit juice with Midfix 1 Injection 5 ml as it may increase the adverse effects of Midfix 1 Injection 5 ml. Also, avoid alcohol consumption with Midfix 1 Injection 5 ml as it may increase the sedative effect. Inform your doctor if you are taking St. John's wort (a herbal medicine).

Drug-Disease Interaction: If you have a lung or breathing disorder, myasthenia gravis (muscle weakness), history of drug abuse or personality disorder, or kidney, liver or heart problems, inform your doctor before taking Midfix 1 Injection 5 ml.

• DILTIAZEM
• NIFEDIPINE
• VERAPAMIL
• FLUCONAZOLE
• KETOCONAZOLE
• VORICONAZOLE
• ITRACONAZOLE
• POSACONAZOLE
• CLARITHROMYCIN
• ERYTHROMYCIN
• ROXITHROMYCIN
• RIFAMPICIN
• ATORVASTATIN
• SAQUINAVIR
• PHENYTOIN
• CARBAMAZEPINE
• FENTANYL
• DIAZEPAM

If you receive Midfix 1 Injection 5 ml for prolonged periods, it may cause dependence and withdrawal symptoms. Therefore, do not stop taking Midfix 1 Injection 5 ml suddenly. Your doctor will reduce the dose gradually to avoid withdrawal symptoms.

Conscious sedation: It is a technique in which drugs help you relax (sedative), reduce anxiety and inhibit pain (anaesthetic) during a medical test or procedure. You will stay awake but may not be able to speak. It is usually referred to as procedural sedation and analgesia.