Ismo Retard Tablet 7's

Written By aquibnaseer ,

Reviewed By Sunny S , MBBS

MRP ₹140.5

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Whats That

About Ismo Retard Tablet

Ismo Retard Tablet belongs to the class of organic nitrates with blood vessel dilating activity. It is used for a heart condition called angina pectoris in which blood vessels of the heart get narrowed in an unexpected and sudden manner leading to decreased blood flow to the muscles of the heart leading to its suffocation & thus leading to a tight pain in the chest, neck or arm area.

Ismo Retard Tablet a mononitrate form of isosorbide is a powerful vasodilator (widens blood vessels). It works by the formation of the free radical nitric oxide (NO) inside our body which leads to the relaxation of muscles of blood vessels, especially of the heart leading to proper blood flow towards the heart muscle which has been working under immense pressure due to decreased blood flow to it.

Ismo Retard Tablet should be taken as prescribed by your doctor, with or without a meal at fixed intervals every day for best results. The dose of Ismo Retard Tablet can vary depending upon your condition and the severity of the condition. Also, it is recommended to complete the course of medicine even if you feel better. The common side effects of Ismo Retard Tablet include nausea, dizziness & headache. Everyone need not experience the above side effects. In case of any discomfort, speak with a doctor.

Before starting Ismo Retard Tablet, please inform your doctor if you have any allergy (against any nitrate), have suffered a heart attack/stroke, or have an eye disease called glaucoma. Do not take Ismo Retard Tablet on your own as, self-medication. If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.

Uses of Ismo Retard Tablet

Angina Pectoris.

Directions for Use

Take Ismo Retard Tablet at the start of a meal or slightly before or as advised by your doctor. Swallow it as a whole with a glass of water. Do not chew or crush it. Space the doses evenly during the entire course.

Medicinal Benefits

Ismo Retard Tablet belongs to a class of medicines called nitrate vasodilators. These operate by relaxing the blood vessels of the heart, reducing the stress on the heart and making it easier to pump blood. Ismo Retard Tablet is used to prevent attacks of angina pectoris. Angina usually feels like tight chest pain, neck or arm area. The pain originates from the heart muscle and is a sign that part of it is not getting enough oxygen for the amount of work it is doing.

Side effects of Ismo Retard Tablet

Headache

Dealing with Medication-Induced Headache:

Hydrate your body: Drink enough water to prevent dehydration and headaches.
Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
Take rest: lie down in a quiet, dark environment.
Cold or warm compresses can help reduce tension.
Stay Upright: Maintain good posture to keep symptoms from getting worse.
To treat headaches naturally, try acupuncture or massage therapy.
Over-the-counter pain relievers include acetaminophen and ibuprofen.
Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
Frequent Headaches: If you get reoccurring headaches, consult your doctor.
Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Pain

Apply a hot/cold pack to the affected area.
Doing gentle exercises can help cope with pain by stretching muscles.
Get enough sleep. It helps enhance mood and lower pain sensitivity.
Avoid alcohol, smoking and tobacco as they can increase pain.
Follow a well-balanced meal.
Meditation and massages may also help with pain.

Nausea

Overcome Medication-Induced Nausea: A 9-Step Plan

Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
Divide your daily food intake into smaller, more frequent meals to reduce nausea.
Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
Use ginger (tea, ale, or candies) to help relieve nausea.
Get adequate rest and also avoid strenuous activities that can worsen nausea.
Talk to your doctor about taking anti-nausea medication if your nausea is severe.
Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Sleep Disturbances

Reddening Of The Face

Managing Medication-Triggered Flushing (Reddening of the skin): A Step-by-Step Guide:

Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.

Drug Warnings

Communicate to your doctor or pharmacist before taking Ismo Retard Tablet if a patient has low performing thyroid gland, is undernourished because of a poor diet, has severe liver/kidney problems, suffers from hypothermia (very low body temperature), suffers from very poor blood circulation, has had any lethal damage to heart such as a heart attack or suffers from a disease called glaucoma (increased pressure in the eye).

Drug-Drug Interactions

Isosorbide mononitrateTadalafil

Critical

Isosorbide mononitrateRiociguat

Critical

Drug-Drug Interactions

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Isosorbide mononitrateTadalafil

Critical

How does the drug interact with Ismo Retard Tablet:
Coadministration of Tadalafil with Ismo Retard Tablet can increase the risk or severity of low blood pressure.

How to manage the interaction:
Taking Ismo Retard Tablet with Tadalafil is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience dizziness, or heart palpitations. Do not discontinue any medications without consulting a doctor.

Isosorbide mononitrateRiociguat

Critical

How does the drug interact with Ismo Retard Tablet:
Taking Riociguat with Ismo Retard Tablet can cause low blood pressure.

How to manage the interaction:
Taking Ismo Retard Tablet with Riociguat is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience dizziness, lightheadedness, fainting, headache, flushing, heart palpitations, priapism in males (persistent and painful erection unrelated to sexual activity). Do not discontinue any medications without consulting a doctor.

Isosorbide mononitrateSodium nitrite

Severe

How does the drug interact with Ismo Retard Tablet:
Taking Ismo Retard Tablet with sodium nitrite may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although taking Ismo Retard Tablet and sodium nitrite together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.

Isosorbide mononitrateTizanidine

Severe

How does the drug interact with Ismo Retard Tablet:
Taking Ismo Retard Tablet with tizanidine will have an additive effect and may lower blood pressure.

How to manage the interaction:
Although taking Ismo Retard Tablet and tizanidine together can possibly result in an interaction, but it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as headache, dizziness, lightheadedness, fainting, and/or pulse or heart rate changes. Do not stop using any medications without consulting doctor.

Isosorbide mononitrateDihydroergotamine

Severe

How does the drug interact with Ismo Retard Tablet:
Taking Ismo Retard Tablet together with dihydroergotamine can increase the effects of dihydroergotamine.

How to manage the interaction:
Although taking Ismo Retard Tablet and dihydroergotamine together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience an irregular heartbeat, nausea, vomiting, weakness, or coldness, numbness, chest pain or pain in the hands, feet, arms, or legs. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Adopting a heart-healthy lifestyle will help you keep your cholesterol and blood pressure down, keep your arteries clear and avoid angina.
Eat plenty of fruits, vegetables, whole grains and low-fat sources of protein such as nuts and fish.
Regularly workout.
Maintain a healthy weight and keep your diabetes in check.
Stop smoking.

Side Effects of Ismo Retard Tablet

Fainting
Low blood pressure
Headache
Dizziness
Nausea
Swelling of eyelids, face or lips
Rash or itching especially those covering your whole body
Exfoliative dermatitis (serious illness with blistering of the skin, mouth, eyes and genitals)

Habit Forming

No

Therapeutic Class

ANTIANGINALS

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Author Details

Reviewed By

Sunny S

MBBS

Last Updated

Jul 8, 2025 | 9:31 AM IST

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Drug-Diseases Interactions

No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

What to do if i miss a dose?

Take the missed dose as soon as possible, if its been too late then jumo to next dose and never attempt to take double dose as it may lead to serious harmful implications.

is Ismo Retard Tablet safe with antihypertensives?

Strictly no, drastic fall in blood pressure is seen & is never advised except for a few antihypertensives that too only under doctors consultation.

Is this drug safe with migraine medications?

No, ergot based drugs have been found to have interaction with Ismo Retard Tablet thus not advised.

is Ismo Retard Tablet safe in patients taking viagra?

No, the interaction produced causes severe hypotension or decrease in blood pressure.

What are the effectsof an overdose of Ismo Retard Tablet?

It can induce throbbing headache, reddening of the skin chills along with sweating, nausea, vomiting, and quick heartbeat if you take more than the prescribed dose of Ismo Retard Tablet. Seek emergency treatment and seek urgent consultation with your doctor if you are taking more than the prescribed dosage of this drug.

Drug-Drug Interactions Checker List

SILDENAFIL
ISOSORBIDE DINITRATE
CAPTOPRIL
CLONIDINE
MOXONIDINE
DIHYDROERGOTAMINE
AMITRIPTYLINE

Special Advise

Avoid vigorous physical activity that may aggravate anginal attack.
Avoid smoking.
A patient should avoid places where airflow is restricted.

Disease/Condition Glossary

Angina or chest pain: It is the most common indication of heart disease caused due to decreased blood flow to heart muscles. The heart is dependent on oxygen for its functioning and pumping of blood yet sometimes due to various genetic and environmental reasons the blood vessels supplying blood to the heart narrow unexpectedly causing decreased blood flow to the heart. This abrupt decrease in blood flow leads to increased stress on the heart to pump blood towards different organs causing an event of acute chest pain that starts from the arm along the jaw and finally involves the chest. Angina pectoris is of 3 types:

1) Stable Angina: is the most common type in which blood flow to the heart is low as compared to what it needs to function, caused by increased physical activity.

2) Unstable angina: is the most lethal type in which blood supply to the heart decreases abruptly due to blockage of the artery by a clot etc.

3) Variant angina: occurs at rest due to spasmic narrowing of the artery.