Ixapana 20Mg Capsule 6'S

Written By Bayyarapu Mahesh Kumar , M Pharmacy

Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

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MRP ₹79860

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₹9583.2 Cashback (12%)

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About Ixapana 20Mg Capsule

Ixapana 20Mg Capsule belongs to the group of anti-cancer medicines used to treat multiple myeloma. Multiple myeloma, also known as myeloma, is a type of bone marrow cancer that affects several areas of the body, such as the spine, skull, pelvis, and ribs.

Ixapana 20Mg Capsule contains Panobinostat. It works by blocking the action of histone deacetylase in myeloma cells. Thereby, it can prevent myeloma cells from growing and multiplying.

Depending on your medical condition, you are advised to take Ixapana 20Mg Capsule for as long as your doctor prescribes it. Sometimes, you may experience common side effects, such as diarrhoea, fatigue, nausea, peripheral oedema, decreased appetite, pyrexia, vomiting and hematologic laboratory abnormalities. Do not be reluctant to talk with your doctor if you persistently experience any of these side effects.

Do not take Ixapana 20Mg Capsule if you are allergic to any of its components or if you are pregnant. Do not try to become pregnant as Ixapana 20Mg Capsule may cause Embryo-Fetal Toxicity. Advise women not to breastfeed while taking Ixapana 20Mg Capsule. Inform your doctor if you are suffering from Hepatic dysfunction, as this increases panobinostat exposure. Your doctor reduces the dose in patients with mild to moderate hepatic (liver) impairment. It is recommended not to be used in people with severe hepatic (liver) impairment. If you feel dizzy or lightheaded when taking panobinostat, you should not operate machinery or drive a car.

Uses of Ixapana 20Mg Capsule

Multiple myeloma

Directions for Use

Swallow it as a whole with water; do not crush or chew it.

Medicinal Benefits

Ixapana 20Mg Capsule contains Panobinostat, which belongs to the anti-cancer medicines used to treat multiple myeloma. It works by blocking the action of histone deacetylase in myeloma cells. Thereby, it can prevent myeloma cells from growing and multiplying.

Side effects of Ixapana 20Mg Capsule

Loose And Watery Stools

Here are the precise steps to cope with diarrhoea caused by medication usage:

Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Decreased Production Of Blood Cells

Eat well-cooked food to minimize infection risk.
Practice good hand hygiene to prevent infections.
Avoid crowds and people with illnesses to reduce exposure.
Wear a mask when necessary to lower infection risk.
Rest adequately to support your body's healing process.
Stay hydrated by drinking plenty of water.
Regularly monitor blood cell counts for changes.
Seek immediate medical help if symptoms like fever, chills, or fatigue occur.
Consult your doctor right away if concerning symptoms arise.
Follow your doctor's guidance on managing myelosuppression and infection prevention.

Liver Damage

Avoid alcohol as it may be harmful and worsen certain condition.
Take nutritional supplements only as advised by your doctor.
Limit sodium intake.
Consult your doctor for medications to treat your condition effectively.

Harmful Effects On The Embryo Or Fetus

Low Platelet Count

Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
If you experience severe bleeding or bruising, seek emergency medical attention immediately.

Fatigue

Rest well; get enough sleep.
Eat a balanced diet and drink enough water.
Manage stress with yoga and meditation.
Limit alcohol and caffeine.
Physical activities like walking or jogging might help boost energy and make you feel less tired.

Drug Warnings

Do not take Ixapana 20Mg Capsule if you are allergic to any of its contents. Inform your doctor about your health condition and medications to rule out any side effects/interactions. Always take this medicine exactly as your doctor or healthcare professional has told you. To treat your condition effectually, continue taking Ixapana 20Mg Capsule for as long as your doctor has prescribed. Do not stop Ixapana 20Mg Capsule midway. Talk to your doctor before taking Ixapana 20Mg Capsule if you have severe allergic reactions to Ixapana 20Mg Capsule or other medicines or suffer from any medical illness. Avoid taking Ixapana 20Mg Capsule if you are pregnant or breastfeeding because this Ixapana 20Mg Capsule can cause harmful effects on the unborn baby. Both women and men using this Ixapana 20Mg Capsule should use birth control to avoid pregnancy. Inform your doctor if you have a history of low blood pressure; your doctor will closely monitor and manage it. If you are taking medication to help lower your blood pressure, you may need to reduce or discontinue it while taking panobinostat.

Drug-Drug Interactions

PanobinostatRifabutin

Critical

PanobinostatPiroxicam

Severe

Drug-Drug Interactions

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PanobinostatRifabutin

Critical

How does the drug interact with Ixapana 20Mg Capsule:
Taking Rifabutin and Ixapana 20Mg Capsule may significantly reduce the blood levels of Ixapana 20Mg Capsule.

How to manage the interaction:
Taking Rifabutin with Ixapana 20Mg Capsule is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately, iff you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.

PanobinostatPiroxicam

Severe

How does the drug interact with Ixapana 20Mg Capsule:
Using Ixapana 20Mg Capsule together with piroxicam may increase the risk of bleeding.

How to manage the interaction:
Although there is a possible interaction between Piroxicam and Ixapana 20Mg Capsule, you can take these medicines together if prescribed by a doctor. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not discontinue any medications without consulting a doctor.

PanobinostatKetoconazole

Severe

How does the drug interact with Ixapana 20Mg Capsule:
Taking Ketoconazole and Ixapana 20Mg Capsule together can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Ketoconazole and Ixapana 20Mg Capsule together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, consult a doctor immediately. Do not stop using any medications without a doctor's advice.

PanobinostatBosutinib

Severe

How does the drug interact with Ixapana 20Mg Capsule:
Taking Bosutinib and Ixapana 20Mg Capsule can raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Although there is an interaction between bosutinib and Ixapana 20Mg Capsule, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, or fainting. Do not discontinue any medications without consulting a doctor.

PanobinostatCiprofloxacin

Severe

How does the drug interact with Ixapana 20Mg Capsule:
Taking ciprofloxacin and Ixapana 20Mg Capsule together can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking ciprofloxacin and Ixapana 20Mg Capsule together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

PanobinostatMoxifloxacin

Severe

How does the drug interact with Ixapana 20Mg Capsule:
Using Ixapana 20Mg Capsule together with Moxifloxacin can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Moxifloxacin with Ixapana 20Mg Capsule can result in an interaction, but it can be taken if a doctor has advised it. If you experience irregular heart rhythm, dizziness, or shortness of breath, call a doctor right away. Do not stop using any medications without talking to a doctor.

PanobinostatAzithromycin

Severe

How does the drug interact with Ixapana 20Mg Capsule:
Taking Azithromycin with Ixapana 20Mg Capsule increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Although administration of azithromycin alongside Ixapana 20Mg Capsule can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.

PanobinostatOndansetron

Severe

How does the drug interact with Ixapana 20Mg Capsule:
Taking Ondansetron with Ixapana 20Mg Capsule increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Co-administration of Ondansetron along with Ixapana 20Mg Capsule can result in an interaction, it can be taken if a doctor has advised it. However, consult a doctor if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat. Do not discontinue any medications without a doctor's advice.

PanobinostatNilotinib

Severe

How does the drug interact with Ixapana 20Mg Capsule:
Combining Ixapana 20Mg Capsule and nilotinib can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Ixapana 20Mg Capsule and nilotinib together can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.

PanobinostatFluvoxamine

Severe

How does the drug interact with Ixapana 20Mg Capsule:
Taking Fluvoxamine and Ixapana 20Mg Capsule together may increase the risk of bleeding.

How to manage the interaction:
Co-administration of Fluvoxamine with Ixapana 20Mg Capsule can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any of the following symptoms - bleeding problems, bleeding, confusion, fast heartbeat, shaking, feeling sick, pain, swelling, headache, dizziness, weakness, vaginal bleeding, nosebleeds, bleeding gums, bruising, heart palpitations, fainting, chest pain, muscle stiffness, bruising, feeling dizzy, dark or bloody stools, severe headache, or bleeding or vomiting - please contact your doctor right away. Do not stop using any medications without talking to your doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
Performing yoga may also help in improving both physical and mental health.
Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
Eat a healthy diet and exercise regularly to maintain proper weight.
Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
Get optimal sleep; rest well.
Avoid smoking and alcohol consumption.
Avoid fast food, fried food, processed meats, refined carbs and added sugars.

Side Effects of Ixapana 20Mg Capsule

Nausea
Vomiting
Appetite loss
Feel dizzy
Lightheaded
Low blood pressure
Diarrhea
Fatigue (tiredness)
Peripheral edema
Decreased appetite
Pyrexia
Vomiting
Hematologic laboratory abnormalities

Habit Forming

No

Therapeutic Class

CHEMOTHERAPY

Author Details

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 8, 2025 | 9:49 AM IST

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Drug-Diseases Interactions

No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

How does Ixapana 20Mg Capsule work?

Ixapana 20Mg Capsule contains Panobinostat. It works by blocking the action of histone deacetylase in myeloma cells. Thereby, it can prevent myeloma cells from growing and multiplying.

Can I stop taking Ixapana 20Mg Capsule on my own?

Do not stop taking Ixapana 20Mg Capsule on your own. Depending on your medical condition, you are advised to take Ixapana 20Mg Capsule for as long as your doctor prescribes it. Do not hesitate to speak with your doctor if you experience difficulty taking Ixapana 20Mg Capsule.

Is it safe to father a child while taking Ixapana 20Mg Capsule?

No, it is unsafe to father a child while taking Ixapana 20Mg Capsule. It is recommended for sexually active men to use condoms while on treatment and for at least six months after their last dose of Ixapana 20Mg Capsule.

Does Ixapana 20Mg Capsule affect blood cell count?

The amount of red blood cells, white blood cells, and platelets in your blood may decrease as a result of Ixapana 20Mg Capsule. This can lead to anaemia (shortness of breath, exhaustion, and weakness) and fatigue, and make you more prone to infection and increase your risk of bleeding. You will be given supportive medication to alleviate these adverse effects and increase your blood cell count if necessary.

Does Ixapana 20Mg Capsule cause fluid retention?

Panobinostat can induce swelling in the hands, ankles, and feet (peripheral oedema). Fluid may also accumulate around the abdomen, making you feel bloated. Your doctor will discuss a treatment strategy for your fluid retention with you. Diuretics (water tablets) are typically used to assist your body in removing excess fluid.

Drug-Drug Interactions Checker List

ALFUZOSIN
APIXABAN
BCG VACCINE
DENGUE VACCINE
CLARITHROMYCIN
CIPROFLOXACIN
DABIGATRAN
EFAVIRENZ
FINGOLIMOD

Special Advise

Monitoring of complete blood count while taking Ixapana 20Mg Capsule is advised.
Drink plenty of fluids to prevent urinary problems.
If you are due to have any surgery, inform the doctor that you are taking Ixapana 20Mg Capsule.
Insomnia or difficulty sleeping at night is a common side effect of panobinostat. This may be minimised by taking panobinostat in the morning.

Disease/Condition Glossary

Multiple myeloma, also known as myeloma, is a type of bone marrow cancer that affects several areas of the body, such as the spine, skull, pelvis, and ribs.