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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sunny S , MBBS

About Izra-D 20 Capsule 10's

Izra-D 20 Capsule 10's belongs to a group of gastrointestinal agents used to treat gastroesophageal reflux disease (GERD), Zollinger-Ellison syndrome, and stomach ulcers. The stomach is usually protected from acid by a mucous layer. In some cases, due to excess acid production, the mucous layer gets eroded, which leads to complications like GERD, acidity, peptic ulcers and Zollinger-Ellison syndrome.

Izra-D 20 Capsule 10's is a combination of two drugs: Esomeprazole (proton pump inhibitor) and Domperidone (a dopamine antagonist). Esomeprazole works by blocking an enzyme called gastric proton pump, which is responsible for the production of acid Domperidone works by increasing the movements and contractions of stomach muscle. Together, Izra-D 20 Capsule 10's helps in treating acidity-related problems.

You are advised to take Izra-D 20 Capsule 10's for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as dry mouth, stomach pain, diarrhoea, headache, and flatulence. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Consult your doctor before taking Izra-D 20 Capsule 10's if you are pregnant or breastfeeding. Izra-D 20 Capsule 10's may cause dizziness, so drive only if you are alert. Izra-D 20 Capsule 10's should not be given to children as safety has not been established. Avoid consuming alcohol and Izra-D 20 Capsule 10's as it could lead to increased drowsiness and elevate stomach acid production. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

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Whats That

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Non returnable*
COD available

Online payment accepted

Manufacturer/Marketer

Torrent Pharmaceuticals Ltd

Consume Type

ORAL

Return Policy

3 Days Returnable

Expires on or after

Apr-24

for this medicine

Uses of Izra-D 20 Capsule 10's

Gastroesophageal reflux disease (GERD), Zollinger-Ellison syndrome, Stomach ulcers

Medicinal Benefits

Izra-D 20 Capsule 10's is a combination of two drugs: Esomeprazole and Domperidone. Izra-D 20 Capsule 10's is used to treat gastroesophageal reflux disease (GERD), Zollinger-Ellison syndrome, and stomach ulcers. It may also be indicated in the treatment of nausea, vomiting, fullness of the stomach, belching, heavy bloating, heartburn, acidity, gas, upper abdominal pain, erosive oesophagitis, and swallowing problems. Esomeprazole is a proton pump inhibitor that blocks an enzyme called gastric proton pump, responsible for acid production. Domperidone is a dopamine antagonist which works by increasing the movements and contractions of stomach muscles. Together, Izra-D 20 Capsule 10's helps in treating acidity-related problems.

Side Effects of Izra-D 20 Capsule 10's

  • Dry mouth
  • Stomach pain
  • Diarrhoea
  • Headache
  • Flatulence

Directions for Use

Take Izra-D 20 Capsule 10's 1 hour prior to food. Swallow Izra-D 20 Capsule 10's as a whole with a glass of water; do not chew or crush it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Izra-D 20 Capsule 10's if you are allergic to any of its contents or other proton pump inhibitors (such as pantoprazole, rabeprazole, lansoprazole or omeprazole); if you are taking nelfinavir (used to treat HIV); if you have prolactinoma (tumour of the pituitary gland), blockage in intestines, bleeding in stomach or intestine, moderate to severe liver disease, low level of potassium or magnesium or high levels of magnesium, or heart problems. Inform your doctor before taking Izra-D 20 Capsule 10's if you have severe kidney, heart or liver disease, or if you are due to have Chromogranin A blood test; if you have fungal infections, heart problems or HIV infection. Talk to your doctor if you experience weight loss, problems with swallowing, stomach pain, indigestion, vomit food or blood, or if you pass black stools while taking Izra-D 20 Capsule 10's. On long-term treatment, Izra-D 20 Capsule 10's may cause low magnesium levels, vitamin B12 levels, and might increase the risk of bone fractures; the doctor may advise regular tests for monitoring your condition. Consult your doctor if you are pregnant or breastfeeding. Izra-D 20 Capsule 10's may cause dizziness, so drive only if you are alert. Izra-D 20 Capsule 10's should not be given to children as safety has not been established. Avoid consuming alcohol along with Izra-D 20 Capsule 10's as it could lead to increased drowsiness and can elevate the production of stomach acid. A prolonged intake of Izra-D 20 Capsule 10's is linked with a greater risk of Clostridium difficile-associated diarrhoea, so if you develop diarrhoea that does not improve, immediately consult a doctor. 

Therapeutic Class

GASTROINTESTINAL AGENTS

Drug-Drug Interactions

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EsomeprazoleRilpivirine
Critical
EsomeprazolePazopanib
Severe

Drug-Drug Interactions

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EsomeprazoleRilpivirine
Critical
How does the drug interact with Izra-D 20 Capsule 10's:
Izra-D 20 Capsule 10's may reduce rilpivirine absorption and blood levels, making the medicine less effective against HIV.

How to manage the interaction:
Although taking Izra-D 20 Capsule 10's with Rilpivirine can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if your symptoms do not improve. Do not discontinue using any medications without consulting a doctor.
EsomeprazolePazopanib
Severe
How does the drug interact with Izra-D 20 Capsule 10's:
Izra-D 20 Capsule 10's decreases the absorption of Pazopanib. This results in reduced efficacy of Pazopanib.

How to manage the interaction:
Although taking Izra-D 20 Capsule 10's and Pazopanib can possibly result in an interaction, they can be taken together if prescribed by your doctor. Do not stop taking any medications without consulting your doctor.
EsomeprazoleDacomitinib
Severe
How does the drug interact with Izra-D 20 Capsule 10's:
Izra-D 20 Capsule 10's can make Dacomitinib less effective by reducing its absorption and lowering its concentration in the blood.

How to manage the interaction:
Co-administration of Izra-D 20 Capsule 10's with Dacomitinib can result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to your doctor.
EsomeprazoleAcalabrutinib
Severe
How does the drug interact with Izra-D 20 Capsule 10's:
Izra-D 20 Capsule 10's may interfere with the absorption of Acalabrutinib and reduce their efficacy.

How to manage the interaction:
Taking Izra-D 20 Capsule 10's with Acalabrutinib together can result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to your doctor.
EsomeprazoleDasatinib
Severe
How does the drug interact with Izra-D 20 Capsule 10's:
Using Dasatinib together with Izra-D 20 Capsule 10's may decrease the levels of Dasatinib.

How to manage the interaction:
Although taking Izra-D 20 Capsule 10's together with Dasatinib can result in an interaction, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
EsomeprazoleCitalopram
Severe
How does the drug interact with Izra-D 20 Capsule 10's:
Combining Izra-D 20 Capsule 10's with Citalopram can increase the risk of irregular heart rhythm. .

How to manage the interaction:
Co-administration of Izra-D 20 Capsule 10's with Citalopram can possibly result in an interaction, but it can be taken if your doctor has advised it. If you're having any symptoms like irregular heart rhythm, dizziness, fainting, or shortness of breath, it's important to contact your doctor immediately. Do not stop using any medications without a doctor's advice.
EsomeprazoleErlotinib
Severe
How does the drug interact with Izra-D 20 Capsule 10's:
Coadministration of erlotinib and Izra-D 20 Capsule 10's can reduce effects of erlotinib.

How to manage the interaction:
Taking Erlotinib and Izra-D 20 Capsule 10's together is generally avoided as it can possibly result in an interaction. It can be taken if your doctor has advised it. Do not stop using any medications without first talking to your doctor.
EsomeprazoleNelfinavir
Severe
How does the drug interact with Izra-D 20 Capsule 10's:
Taking nelfinavir with Izra-D 20 Capsule 10's may decrease the effects of nelfinavir.

How to manage the interaction:
Although taking Izra-D 20 Capsule 10's and Nelfinavir can possibly result in an interaction, they can be taken together if prescribed by your doctor. Do not stop taking any medications without consulting your doctor.
EsomeprazoleClopidogrel
Severe
How does the drug interact with Izra-D 20 Capsule 10's:
Coadministration of Clopidogrel with Izra-D 20 Capsule 10's may reduce the effectiveness of clopidogrel.

How to manage the interaction:
Taking clopidogrel and Izra-D 20 Capsule 10's together possibly has an interaction, but you can take these medications together if your doctor has advised it. Do not stop using any medications without talking to your doctor.
EsomeprazoleMethotrexate
Severe
How does the drug interact with Izra-D 20 Capsule 10's:
Co-administration of methotrexate and Izra-D 20 Capsule 10's can increase the blood levels and side effects of methotrexate.

How to manage the interaction:
Although taking Izra-D 20 Capsule 10's with Methotrexate can result in an interaction, they can be taken together if prescribed by a doctor. However, contact your doctor if you experience headache, dizziness, nausea and vomiting. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • ATAZANAVIR
  • SAQUINAVIR
  • RITONAVIR
  • NELFINAVIR
  • WARFARIN
  • CLOPIDOGREL
  • KETOCONAZOLE
  • ITRACONAZOLE
  • VORICONAZOLE
  • FLUCONAZOLE
  • ERLOTINIB
  • TOREMIFENE
  • VANDETANIB
  • VINCAMINE
  • DIAZEPAM
  • PHENYTOIN
  • CILOSTAZOL
  • CISAPRIDE
  • DOLASETRON
  • TACROLIMUS
  • RIFAMPICIN
  • ERYTHROMYCIN
  • CLARITHROMYCIN
  • MOXIFLOXACIN
  • PENTAMIDINE
  • TELITHROMYCIN
  • LEVOTHYROXINE
  • METHOTREXATE
  • CITALOPRAM
  • ESCITALOPRAM
  • DIGOXIN
  • HALOFANTRINE
  • HALOPERIDOL
  • PIMOZIDE
  • SERTINDOLE
  • MEQUITAZINE
  • MIZOLASTINE
  • AMIODARONE
  • DRONEDARONE
  • QUINIDINE
  • DISOPYRAMIDE
  • DOFETILIDE
  • SOTALOL
  • DILTIAZEM
  • VERAMAPIL

Diet & Lifestyle Advise

  • Eat smaller meals more often.
  • Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.
  • Maintain a healthy weight by regular exercising.
  • Avoid lying down after eating as it causes acid reflux.
  • Avoid tight-fitting clothes as it might increase the pressure on the abdomen leading to acid reflux.
  • Practise relaxation techniques and avoid stress by doing yoga or meditation.
  • Avoid foods such as high-fat food, spicy food, chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea and soda. 
  • Avoid sitting continuously as it may trigger acidity. Take a break of 5minutes every hour by doing brisk walking or stretching.

Habit Forming

No

Special Advise

  • Inform your doctor before taking Izra-D 20 Capsule 10's if you are due to have Chromogranin A blood test.
  • Izra-D 20 Capsule 10's may cause changes in blood tests. Inform the person doing the tests that you are taking Izra-D 20 Capsule 10's.

Author Details

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Disease/Condition Glossary

Gastroesophageal reflux disease (GERD): It occurs when stomach acid frequently flows back into the food pipe (oesophagus). This backflow (acid reflux) irritates the food pipe and causes heartburn. Symptoms include heartburn, sour or bitter taste in the mouth, and difficulty swallowing.

Stomach/Peptic ulcers: They are sores that develop on the stomach and intestine lining due to erosion of the stomach's protective lining. Symptoms include nausea, appetite changes, bloody or dark stools, unexplained weight loss, vomiting, and indigestion.

Zollinger-Ellison syndrome: It is characterised by the formation of tumours in the upper part of the small intestine, which leads to excess acid production. Symptoms include bloating, burping, weight loss, loss of appetite, nausea, and vomiting. 

Izra-D 20 Capsule 10's Substitute

Substitutes safety advice
  • Nexpro RD 20 Capsule 10's

    12.60per tablet
  • Sompraz D 20 Capsule 15's

    by AYUR

    12.00per tablet
  • Esoz D 20 Capsule 15's

    by AYUR

    15.12per tablet
  • Esotrend D Capsule 10's

    by AYUR

    10.62per tablet
  • Esomac D 20 Capsule 10's

    11.61per tablet
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