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  3. Johnlee Metoclopramide Injection

Johnlee Metoclopramide Injection, Pack of 1 Injection
Johnlee Metoclopramide Injection, Pack of 1 Injection
Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
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Composition :

METOCLOPRAMIDE-5MG

Manufacturer/Marketer :

Johnlee Pharmaceuticals Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

About Johnlee Metoclopramide Injection

Johnlee Metoclopramide Injection belongs to a group of medicines called anti-emetics and prokinetic agents used to prevent nausea and vomiting caused by chemotherapy, radiotherapy, migraine, and in post-operative conditions. Additionally, Johnlee Metoclopramide Injection is also used to treat delayed gastric emptying. Johnlee Metoclopramide Injection may be used to facilitate small bowel intubation and to stimulate gastric emptying and intestinal transit of barium.

Johnlee Metoclopramide Injection contains ‘metoclopramide’ that works by increasing the motility of the upper gastrointestinal tract; this allows faster transit of food and treats gastric emptying. It also works on the part of the brain that controls vomiting, thereby helps in preventing nausea and vomiting.

In some cases, Johnlee Metoclopramide Injection may cause common side-effects such as drowsiness, fatigue, dizziness, headache, and bowel disturbances. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.

Consult your doctor if you are pregnant or breastfeeding. Johnlee Metoclopramide Injection may cause drowsiness and dizziness affecting your ability to drive and operate machinery. Johnlee Metoclopramide Injection is not recommended for children below one year. Avoid consuming alcohol while on treatment with Johnlee Metoclopramide Injection as it could lead to increased drowsiness. Treatment with Johnlee Metoclopramide Injection is not recommended for longer than 12 weeks, except in rare cases.

Uses of Johnlee Metoclopramide Injection

Nausea, vomiting, delayed gastric emptying

Directions for Use

Johnlee Metoclopramide Injection will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Johnlee Metoclopramide Injection belongs to a group of medicines called anti-emetics and prokinetic agents used to prevent nausea and vomiting caused by chemotherapy, radiotherapy, migraine, and in post-operative conditions. Additionally, Johnlee Metoclopramide Injection is also used to treat delayed gastric emptying. Johnlee Metoclopramide Injection may be used to facilitate small bowel intubation and to facilitate gastric emptying and intestinal transit of barium in patients where delayed emptying interrupts radiological examination of the stomach and/or small intestine. Johnlee Metoclopramide Injection contains ‘metoclopramide’ that works by increasing the motility of the upper gastrointestinal tract; this allows faster transit of food and treats gastric emptying. It also works on the part of the brain that controls vomiting, thereby helps in preventing nausea and vomiting.

Storage

Store in a cool and dry place away from sunlight
Side effects of Johnlee Metoclopramide Injection
  • Stretching and walking are examples of mild exercises that can improve mobility and reduce muscle stiffness.
  • Improving posture, mobility, and muscle coordination through physical therapy can help manage slowness or stiffness.
  • Maintain healthy weight and advance general health depend on eating a balanced diet.
  • Reducing symptoms like tremors or muscle spasms requires adequate sleep and rest.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Restlessness is related to mental health and needs medical attention if it's severe.
  • Regular practice of meditation and yoga can help calm your mind. This can reduce restlessness.
  • Prevent smoking as it can impact your calmness of body and mind.
  • Talk to your friends and family about restlessness, who can provide a solution for why you feel restless.
  • Get sufficient sleep for a minimum of 6-7 hours to reduce restlessness.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.

Drug Warnings

Do not take Johnlee Metoclopramide Injection if you are allergic to any of its components; if you have gastrointestinal bleeding, mechanical obstruction/perforation, pheochromocytoma (tumour in the adrenal glands), or epilepsy. Johnlee Metoclopramide Injection may cause neuroleptic malignant syndrome (a nervous disorder with high fever and muscle stiffness), extrapyramidal symptoms (shaking, tremor, stiffness and involuntary movement), Tardive dyskinesia (movement disorder), Parkinson-like symptoms (bradykinesia, tremor, cogwheel rigidity, or mask-like facies), and depression. Inform your doctor if you have heart problems, diabetes, depression, high blood pressure, breast cancer, seizures, Parkinson’s disease, methaemoglobinaemia, or liver or kidney problems. Consult your doctor immediately if you cannot stop or control movements like shaking your arms and legs, blinking and moving your eyes, sticking out the tongue, frowning, lip-smacking, chewing, or puckering up the mouth.

Drug-Drug Interactions

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MetoclopramideTetrabenazine
Critical
MetoclopramideDuloxetine
Critical

Drug-Drug Interactions

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MetoclopramideTetrabenazine
Critical
How does the drug interact with Johnlee Johnlee Metoclopramide Injection Injection:
Coadministration of Tetrabenazine and Johnlee Metoclopramide Injection can increase the risk of side effects like uncontrolled movement disorder.

How to manage the interaction:
Taking Tetrabenazine and Johnlee Metoclopramide Injection together is not recommended as it can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like muscle spasms or movements that you can't stop or control, such as lip smacking, chewing, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, tremor, restlessness, and foot tapping, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MetoclopramideDuloxetine
Critical
How does the drug interact with Johnlee Johnlee Metoclopramide Injection Injection:
Coadministration of Johnlee Metoclopramide Injection with duloxetine increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Johnlee Metoclopramide Injection with Duloxetine is not recommended, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
MetoclopramideAripiprazole
Critical
How does the drug interact with Johnlee Johnlee Metoclopramide Injection Injection:
Co-administration of Johnlee Metoclopramide Injection with Aripiprazole can increase the risk of side effects.

How to manage the interaction:
Taking Aripiprazole with Johnlee Metoclopramide Injection is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
MetoclopramideMaprotiline
Critical
How does the drug interact with Johnlee Johnlee Metoclopramide Injection Injection:
Co-administration of Johnlee Metoclopramide Injection with Maprotiline can increase the risk or severity of side effects.

How to manage the interaction:
Taking Maprotiline with Johnlee Metoclopramide Injection is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. Consult your doctor if you see symptoms like dizziness, drowsiness, confusion, difficulty concentrating, or impairment in thinking, judgment, and motor coordination. Do not discontinue any medications without consulting a doctor.
MetoclopramideTrazodone
Critical
How does the drug interact with Johnlee Johnlee Metoclopramide Injection Injection:
Coadministration of Johnlee Metoclopramide Injection with Trazodone can rarely increase serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to side effects.

How to manage the interaction:
Taking Johnlee Metoclopramide Injection with Trazodone is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience any symptoms like dizziness, fever, excessive sweating, shivering, blurred vision, muscle stiffness, stomach cramps, nausea, vomiting, or diarrhoea contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
MetoclopramideVenlafaxine
Critical
How does the drug interact with Johnlee Johnlee Metoclopramide Injection Injection:
Coadministration of Johnlee Metoclopramide Injection with Venlafaxine might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to side effects.

How to manage the interaction:
Taking Johnlee Metoclopramide Injection with Venlafaxine together is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.
MetoclopramideMethyldopa
Critical
How does the drug interact with Johnlee Johnlee Metoclopramide Injection Injection:
Taking Methyldopa and Johnlee Metoclopramide Injection together can decrease the levels and effects of Methyldopa.

How to manage the interaction:
Taking Johnlee Metoclopramide Injection with Methyldopa is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.
MetoclopramideCariprazine
Critical
How does the drug interact with Johnlee Johnlee Metoclopramide Injection Injection:
Co-administration of Johnlee Metoclopramide Injection with Cariprazine can increase the risk of side effects.

How to manage the interaction:
Taking Cariprazine with Johnlee Metoclopramide Injection is generally avoided, but can be taken together if prescribed by a doctor. However, if you experience muscle spasms or movements that you can't stop or control, such as lip smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, shaking of hands and legs, jitteriness, restlessness, pacing, and foot tapping, contact a doctor immediately. Do not stop using any medications without talking to a doctor.
MetoclopramideAmoxapine
Critical
How does the drug interact with Johnlee Johnlee Metoclopramide Injection Injection:
Co-administration of Johnlee Metoclopramide Injection with Amoxapine can increase the risk of side effects.

How to manage the interaction:
Taking Johnlee Metoclopramide Injection with Amoxapine is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.
MetoclopramidePromethazine
Critical
How does the drug interact with Johnlee Johnlee Metoclopramide Injection Injection:
Coadministration of Johnlee Metoclopramide Injection with Promethazine can increase the risk of side effects like uncontrolled movement disorder.

How to manage the interaction:
Taking Promethazine with Johnlee Metoclopramide Injection is generally avoided as it can possibly result in an interaction. They can be taken together However, consult a doctor if you experience puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, tremor, jitteriness, restlessness, pacing, and foot tapping. Do not stop taking any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat smaller meals more often.
  • Drink fluids to stay hydrated.
  • Avoid solid foods until vomiting stops.
  • Avoid foods that might cause stomach upset.
  • Take ample rest. Avoid any activity immediately after eating.
  • Consume plain, light foods such as bread and biscuits.
  • Avoid food with strong flavours and fried food.
  • Ginger tea might help in proper digestion.

Habit Forming

No

Therapeutic Class

ANTIEMETICS

Product Substitutes

Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Aug 20, 2024 | 1:14 PM IST

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Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Johnlee Metoclopramide Injection works by increasing the motility of the upper gastrointestinal tract; this allows faster transit of food and treats gastric emptying. It also works on the part of the brain that controls vomiting, thereby helps in preventing nausea and vomiting.

Johnlee Metoclopramide Injection may cause tardive dyskinesia (movement disorder) that is often irreversible. The risk increases with the duration of treatment and dosage. Johnlee Metoclopramide Injection therapy should be discontinued in patients who develop the symptoms of tardive dyskinesia. Consult your doctor immediately if you notice symptoms such as involuntary movements of the face, tongue, mouth, jaw, trunk and/or extremities.

Johnlee Metoclopramide Injection may be used to facilitate small bowel intubation (the process of passing a small, flexible plastic tube through the nose/mouth into the stomach/small intestine) in adults and pediatric patients in whom the tube does not pass the pylorus (the opening from the stomach into the duodenum) with conventional manoeuvres.

Treatment with Johnlee Metoclopramide Injection should be avoided for longer than 12 weeks except in rare cases where benefits outweigh the risks of developing tardive dyskinesia.

Johnlee Metoclopramide Injection may cause depression in people with or without a medical history of depression. Consult your doctor immediately if you have any suicidal thoughts, such as killing or harming yourself.

Johnlee Metoclopramide Injection may be used to facilitate gastric emptying and intestinal transit of barium in patients where delayed emptying interrupts radiological examination of the stomach and/or small intestine.

Drug-Drug Interactions Checker List

  • LEVODOPA
  • DIGOXIN

Disease/Condition Glossary

Nausea/Vomiting: Nausea is an uneasy feeling in which the person feels an urge to vomit, whereas vomiting is an uncontrollable reflex that expels the contents of the stomach through the mouth. Nausea and vomiting may occur separately or together. The common causes include motion sickness, emotional stress, indigestion, food poisoning, high fever or overeating. Nausea/vomiting might also occur as an unpleasant effect of therapy, such as chemotherapy and radiation therapy. 

Gastroparesis: Gastroparesis or delayed gastric emptying is a condition that occurs when the stomach takes too long to empty the food into the intestine. Symptoms include nausea, vomiting, indigestion, loss of appetite, bloating and heartburn.

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