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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Non returnable*
COD available

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About Kafodex Syrup

Kafodex Syrup belongs to a class of medication called 'cough and cold preparations' primarily used to treat dry cough. Coughing (dry or productive) is a body's way of clearing irritants (like allergens, mucus, or smoke) from airways and preventing infection. There are two types of coughs, namely: dry cough and chesty cough. A dry cough is tickly and doesn't produce any vicious or thick mucus, while a chesty cough (wet cough) means mucous or sputum is produced to help clear the airways. 

Kafodex Syrup is a combination of three drugs, namely: Chlorpheniramine maleate (antihistamine), Phenylephrine hydrochloride (decongestant), and Dextromethorphan hydrobromide (cough suppressant). Chlorpheniramine maleate works by blocking the action of histamine, a substance responsible for causing allergic reactions. Phenylephrine hydrochloride helps in shrinking the blood vessels located in the nasal passage, thereby reducing the stuffy nose. Dextromethorphan hydrobromide works by blocking the transmission of nerve signals from the cough centre in the brain to the muscles that produce cough. Together, it helps to provide relief from cough.

Take Kafodex Syrup as prescribed. Your doctor will recommend how often you need to take Kafodex Syrup based on your medical condition. Some people may experience dry mouth, throat or nose, drowsiness, blurred vision, constipation, dizziness, restlessness, or excitation. Most of these side effects of Kafodex Syrup do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are pregnant or breastfeeding, it is advised to inform your doctor before using Kafodex Syrup . Kafodex Syrup is not recommended for children below 12 years of age. If you are about to undergo any medical tests or surgery, please inform your doctor that you are taking Kafodex Syrup . Avoid using Kafodex Syrup if you have taken monoamine oxidase inhibitors in the past 14 days. If you have glaucoma, urinary problems, enlarged prostate, phenylketonuria (a congenital disability that causes accumulation of amino acid, or phenylalanine in the body), cough with mucus or cough caused by asthma, smoking, chronic bronchitis or emphysema (a lung condition causing shortness of breath), inform your doctor before taking Kafodex Syrup . 

Uses of Kafodex Syrup

Dry cough

Directions for Use

Tablet: Take it as advised by the doctor. Swallow it as a whole with water; do not crush, break or chew it.Syrup: Take it with or without food as advised by the doctor. Shake the bottle well before use. Check the label for directions and take it in doses as prescribed by your doctor with the help of a measuring cup/dosing syringe/dropper provided with the pack.

Medicinal Benefits

Kafodex Syrup contains Chlorpheniramine maleate, Phenylephrine hydrochloride, and Dextromethorphan hydrobromide used to treat dry cough. Chlorpheniramine maleate works by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps provide relief from allergy symptoms such as sneezing, running nose, watery eyes, itching, swelling, congestion, or stiffness. Phenylephrine hydrochloride is a decongestant that helps in shrinking the blood vessels located in the nasal passage, thereby reducing the stuffy nose. Dextromethorphan hydrobromide works by blocking the transmission of nerve signals from the cough centre in the brain to the muscles that produce cough. Thus, Kafodex Syrup helps to relieve cough, cold and allergic symptoms.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Kafodex Syrup

  • Dry mouth, throat or nose
  • Drowsiness
  • Dizziness
  • Blurred vision
  • Headache
  • Constipation
  • Restlessness or excitation
  • Loss of appetite

Drug Warnings

If you are allergic to Kafodex Syrup or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Kafodex Syrup . Kafodex Syrup is not recommended for children below 12 years of age. If you are about to undergo any medical tests or surgery, please inform your doctor that you are taking Kafodex Syrup . Avoid taking Kafodex Syrup if you have taken medicines such as linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine and methylene blue injection in the past 14 days. If you have glaucoma, urinary problems, enlarged prostate, phenylketonuria (a birth defect that causes accumulation of amino acid, phenylalanine in the body), cough with mucus or cough caused by asthma, smoking, chronic bronchitis or emphysema (a lung condition causing shortness of breath), inform your doctor before taking Kafodex Syrup .

Drug-Drug Interactions

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DextromethorphanPargyline
Critical
DextromethorphanProcarbazine
Critical

Drug-Drug Interactions

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DextromethorphanPargyline
Critical
How does the drug interact with Kafodex Syrup 100 ml:
Co-administration of Pargyline and Kafodex Syrup 100 ml can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Kafodex Syrup 100 ml and Pargyline can lead to an interaction. However, if you experience any symptoms like confusion, hallucination, seizure, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DextromethorphanProcarbazine
Critical
How does the drug interact with Kafodex Syrup 100 ml:
Co-administration of Kafodex Syrup 100 ml and Procarbazine may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Procarbazine with Kafodex Syrup 100 ml can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms - confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering, shaking, blurred vision, muscle spasm, stiffness, incoordination, stomach cramps, nausea, vomiting, or diarrhea - make sure to contact a doctor right away. Do not stop using any medications without talking to a doctor.
DextromethorphanPhenelzine
Critical
How does the drug interact with Kafodex Syrup 100 ml:
Co-administration of Phenelzine and Kafodex Syrup 100 ml can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Phenelzine and Kafodex Syrup 100 ml can lead to an interaction. However, if you experience any symptoms like confusion, hallucination, seizure, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DextromethorphanRasagiline
Critical
How does the drug interact with Kafodex Syrup 100 ml:
Taking Rasagiline with Kafodex Syrup 100 ml can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Kafodex Syrup 100 ml with Rasagiline is not recommended as it can possibly result in an interaction, it can be taken if a doctor has advised it. If you notice any of these symptoms like confusion, hallucination, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, shaking, incoordination, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor. Do not discontinue any medications without consulting a doctor.
DextromethorphanTranylcypromine
Critical
How does the drug interact with Kafodex Syrup 100 ml:
Taking Tranylcypromine with Kafodex Syrup 100 ml can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Kafodex Syrup 100 ml with Tranylcypromine is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fit blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
DextromethorphanIsocarboxazid
Critical
How does the drug interact with Kafodex Syrup 100 ml:
Co-administration of Isocarboxazid with Kafodex Syrup 100 ml can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Taking Kafodex Syrup 100 ml and Isocarboxazid can lead to an interaction. However, if you experience any symptoms like confusion, hallucination, seizure, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DextromethorphanSelegiline
Critical
How does the drug interact with Kafodex Syrup 100 ml:
Co-administration of Kafodex Syrup 100 ml and Selegiline may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Selegiline with Kafodex Syrup 100 ml can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms - confusion, hallucination, fits, increased heart rate, fever, excessive sweating, shivering, shaking, blurred vision, muscle spasm, stiffness, incoordination, stomach cramps, nausea, vomiting, or diarrhea - make sure to contact a doctor right away. Do not stop using any medications without talking to a doctor.
PhenylephrineSevoflurane
Critical
How does the drug interact with Kafodex Syrup 100 ml:
Co-administration of Kafodex Syrup 100 ml with Sevoflurane can increase the levels of Kafodex Syrup 100 ml and lead to side effects.

How to manage the interaction:
Taking Kafodex Syrup 100 ml with Sevoflurane is not recommended, it can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.
PhenylephrinePropofol
Critical
How does the drug interact with Kafodex Syrup 100 ml:
Taking Kafodex Syrup 100 ml with Propofol may lead to increased levels of Kafodex Syrup 100 ml leading to side effects like high blood pressure.

How to manage the interaction:
Taking Kafodex Syrup 100 ml with Propofol is not recommended, but it can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.
PhenylephrineTranylcypromine
Critical
How does the drug interact with Kafodex Syrup 100 ml:
Taking Tranylcypromine with Kafodex Syrup 100 ml can increase the risk of high blood pressure.

How to manage the interaction:
Taking Tranylcypromine with Kafodex Syrup 100 ml is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and fainting Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid dairy products such as milk as it may increase mucus production. Also, avoid processed or refined foods. 
  • Drink plenty of fluids to avoid a dry throat while you have a cough. It also helps loosen mucus.
  • Avoid citrus fruits as they may worsen the cough. Eat fruits rich in water content, such as pears, watermelon, peaches and pineapples.

Habit Forming

No

Therapeutic Class

COUGH AND COLD PREPARATIONS

Kafodex Syrup Substitute

Substitutes safety advice
  • Alex Sugar Free Syrup 100 ml

    by Others

    1.39per tablet
  • Respicure D Syrup 100 ml

    by AYUR

    1.03per tablet
  • Alkof Junior Syrup 100 ml

    by Others

    1.06per tablet
  • Eascof-D Sugar Free Mixed Fruit Syrup 100 ml

    by AYUR

    1.08per tablet
  • XL-90 Plus Cough Syrup 100 ml

    by XL9

    1.08per tablet

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Kafodex Syrup contains Chlorpheniramine maleate, Phenylephrine hydrochloride, and Dextromethorphan hydrobromide. Chlorpheniramine maleate works by blocking the action of histamine, a substance responsible for causing allergic reactions. Phenylephrine hydrochloride helps in shrinking the blood vessels located in the nasal passage, thereby reducing the stuffy nose. Dextromethorphan hydrobromide works by blocking the transmission of nerve signals from the cough centre in the brain to the muscles that produce cough.

Consult your doctor before taking Kafodex Syrup if you need to undergo surgery as it may lead to excessive drowsiness and sleepiness when given along with anaesthesia. Your doctor may advise you to stop taking Kafodex Syrup 72 hours prior to the surgery.

It is not recommended to take Kafodex Syrup along with any anti-depressant medication, especially MAO inhibitors (linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine), as it may lead to unpleasant side-effects or drug interaction. Also, Kafodex Syrup should be taken at least 14days after your last dose of anti-depressants.

Take the missed dose as soon as you remember. However, if it is almost time for your next dose, wait until then to take Kafodex Syrup and skip the missed dose. Do not take extra medicine to make up for the missed dose.

Kafodex Syrup may rarely worsen the symptoms of glaucoma. Therefore, Kafodex Syrup should be used with caution and only when prescribed by a doctor in patients with glaucoma.

Drug-Drug Interactions Checker List

  • DIPHENHYDRAMINE
  • ESCITALOPRAM
  • DESVENLAFAXINE
  • VILAZODONE
  • ASPIRIN
  • ACETAMINOPHEN
  • AMOXICILLIN
  • LINEZOLID
  • PHENELZINE
  • SELEGILINE
  • RASAGILINE
  • ISOCARBOXAZID
  • TRANYLCYPROMINE
  • METOPROLOL
  • ATENOLOL
  • CARISOPRODOL
  • CYCLOBENZAPRINE

Special Advise

  • Talk to your doctor if your symptoms do not improve even after taking Kafodex Syrup for 7 days.
  • Contact a doctor immediately if you develop fever, rash or headaches after taking Kafodex Syrup . 

Disease/Condition Glossary

Cough: Coughing is a body's way of clearing irritants (like allergens, mucus, or smoke) from airways and preventing infection. Coughs may be dry or productive. A productive cough (wet cough) brings up sputum (phlegm, mucus, and other matter) from the lungs. Cough is commonly caused as a response to allergy or viral infection but coughing up mucus is possibly an infection in the respiratory tract. If you are coughing thick, solid white mucus, you may have a bacterial infection in the airways. If the mucus is clear or light-coloured, you may have allergies or a minor infection in the respiratory tract, and yellow or green mucus indicates a respiratory infection.

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