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Written By Divya L , PharmaD
Reviewed By Veda Maddala , M Pharmacy

About Kezlin 150Mg Inj 2Ml

Kezlin 150Mg Inj 2Ml belongs to the class of 'antibiotics', primarily used to treat serious bacterial infections such as lower respiratory tract infections like pneumonia, empyema, and lung abscess; gynaecological infections like endometritis, nongonococcal tubo-ovarian abscess, pelvic cellulitis, and postsurgical vaginal cuff infection; intra-abdominal infections; septicaemia or sepsis (blood poisoning by bacteria), and bone and joint infections. Bacterial infection occurs when harmful bacteria grow in the body and causes illness. It can infect any part of the body and multiply very quickly. 

Kezlin 150Mg Inj 2Ml contains 'Clindamycin' that works by preventing bacterial protein synthesis, leading to the inhibition of bacterial growth. It shows a bacteriostatic effect that stops bacterial reproduction. Kezlin 150Mg Inj 2Ml effectively treats infections caused by gram-positive and anaerobic (living without air) bacteria, including susceptible strains of Staphylococcus aureus, Streptococcus pneumoniae, and Clostridium perfringens.

Kezlin 150Mg Inj 2Ml will be administered by a healthcare professional. Kezlin 150Mg Inj 2Ml may cause side effects, although not everybody gets them. Common side effects of Kezlin 150Mg Inj 2Ml include stomach pain, nausea, vomiting, diarrhoea, heartburn, skin rash, pain and swelling at the injection site, and vaginal itching or discharge. Most of these side effects do not require medical attention and gradually resolve over time. If these side effects persist longer, please consult your doctor.

Brief your medical history to the doctor if you are allergic to any of the components in Kezlin 150Mg Inj 2Ml. Let your doctor know if you have any liver disease, kidney disease, yellow food dye allergy, colitis (colon inflammation), severe stomach cramps, diarrhoea, and allergic conditions (asthma, hay fever, eczema). Do not use Kezlin 150Mg Inj 2Ml while getting vaccinated with live bacterial vaccines (typhoid vaccine) since Kezlin 150Mg Inj 2Ml may affect the vaccine's activity. Kezlin 150Mg Inj 2Ml should be used only with a doctor's advice during pregnancy and breastfeeding.

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Non returnable*
COD available

Online payment accepted

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

Uses of Kezlin 150Mg Inj 2Ml

Bacterial infections.

Medicinal Benefits

Kezlin 150Mg Inj 2Ml is an antibiotic that treats severe/serious bacterial infections. It works by inhibiting bacterial protein synthesis, which inhibits bacterial growth. It shows a bacteriostatic effect, which stops bacterial reproduction but doesn't kill them. Kezlin 150Mg Inj 2Ml effectively treats infections caused by gram-positive and anaerobic (living without air) bacteria, including susceptible strains of Staphylococcus aureus, Streptococcus pneumoniae, and Clostridium perfringens. Kezlin 150Mg Inj 2Ml is useful in treating lower respiratory tract infections like pneumonia, empyema, and lung abscess; gynaecological infections like endometritis, nongonococcal tubo-ovarian abscess, pelvic cellulitis, and postsurgical vaginal cuff infection; intra-abdominal infections; septicaemia or sepsis (blood poisoning by bacteria), and bone and joint infections.

Side Effects of Kezlin 150Mg Inj 2Ml

  • Pain and swelling at the injection site
  • Stomach pain
  • Nausea
  • Vomiting
  • Diarrhoea
  • Heartburn
  • Skin rash
  • Vaginal itching or discharge 

Directions for Use

Kezlin 150Mg Inj 2Ml will be injected by a healthcare professional. Do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not use Kezlin 150Mg Inj 2Ml if you are allergic to any of its components. Let your doctor know if you have any liver or kidney diseases, gastrointestinal diseases (colitis, Clostridium difficile-associated diarrhoea), yellow food dye allergy, and allergic conditions (asthma, hay fever, eczema). Do not use Kezlin 150Mg Inj 2Ml while getting vaccinated with live bacterial vaccines (typhoid vaccine) since Kezlin 150Mg Inj 2Ml may affect the vaccine's activity. Pregnant and breastfeeding women should consult their doctor before taking Kezlin 150Mg Inj 2Ml. Avoid alcohol consumption to prevent any undesired effects while using Kezlin 150Mg Inj 2Ml.

Therapeutic Class

ANTIBIOTICS

Drug-Drug Interactions

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ClindamycinItraconazole
Severe
ClindamycinCeritinib
Severe

Drug-Drug Interactions

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ClindamycinItraconazole
Severe
How does the drug interact with Kezlin 150Mg Inj 2Ml:
Concomitant use of Kezlin 150Mg Inj 2Ml with itraconazole can reduce the metabolism and increase the levels of Kezlin 150Mg Inj 2Ml in the body. This may increase the risk or severity of side effects.

How to manage the interaction:
Although there is a possible interaction, Kezlin 150Mg Inj 2Ml can be taken with itraconazole if prescribed by the doctor. Consult a doctor immediately if you experience persistent vomiting, nausea, abdominal pain, or diarrhea. Do not stop using any medications without first talking to your doctor.
ClindamycinCeritinib
Severe
How does the drug interact with Kezlin 150Mg Inj 2Ml:
Concomitant use of Kezlin 150Mg Inj 2Ml with ceritinib can increase the effects of Kezlin 150Mg Inj 2Ml

How to manage the interaction:
Although there is a possible interaction, Kezlin 150Mg Inj 2Ml can be taken with ceritinib if prescribed by the doctor. Consult the prescriber if you experience persistent vomiting, nausea, abdominal pain, or diarrhoea.
ClindamycinBotulinum toxin
Severe
How does the drug interact with Kezlin 150Mg Inj 2Ml:
Taking Kezlin 150Mg Inj 2Ml with Botulinum toxin can increase the risk or severity of side effects.

How to manage the interaction:
Taking Kezlin 150Mg Inj 2Ml with Botulinum toxin together can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ClindamycinAmprenavir
Severe
How does the drug interact with Kezlin 150Mg Inj 2Ml:
Co-administration of Amprenavir together with Kezlin 150Mg Inj 2Ml can increase the effects of Kezlin 150Mg Inj 2Ml.

How to manage the interaction:
Co-administration of Kezlin 150Mg Inj 2Ml with Amprenavir can possibly result in an interaction, but it can be taken if a doctor has advised it. If you have ongoing feelings of sickness, throwing up, having loose stools, or pain in your stomach, it's important to contact your doctor right away. Do not stop using any medications without talking to a doctor.
ClindamycinAtracurium
Severe
How does the drug interact with Kezlin 150Mg Inj 2Ml:
Co-administration of Kezlin 150Mg Inj 2Ml with Atracurium can increase the risk of muscle weakness.

How to manage the interaction:
Taking Kezlin 150Mg Inj 2Ml with Atracurium together can possibly result in an interaction, but it can be taken if a doctor has advised it. "Kezlin 150Mg Inj 2Ml can affect the muscles and nerves in your body. When used with other medications that also affect the muscles and nerves, it can cause a serious problem called neuromuscular blockade. If you have trouble breathing or can't breathe at all, please call your doctor right away." Do not stop using any medications without a doctor's advice.
ClindamycinCapreomycin
Severe
How does the drug interact with Kezlin 150Mg Inj 2Ml:
Co-administration of Capreomycin with Kezlin 150Mg Inj 2Ml can increase the risk of kidney or nerve damage.

How to manage the interaction:
There may be a possibility of interaction between Kezlin 150Mg Inj 2Ml and Capreomycin, but it can be taken if prescribed by a doctor. Do not discontinue any medications without first consulting your doctor.
ClindamycinBalsalazide
Severe
How does the drug interact with Kezlin 150Mg Inj 2Ml:
Co-administration of Kezlin 150Mg Inj 2Ml with Balsalazide may reduce the effectiveness of Balsalazide.

How to manage the interaction:
Although there is a possible interaction, Kezlin 150Mg Inj 2Ml can be taken with balsalazide if prescribed by the doctor. Consult the prescriber if you have any concerns, the doctor may prescribe alternatives that do not interact, dose adjustment, or more frequent monitoring to safely use both medications. Do not discontinue the medication without consulting a doctor.
ClindamycinFosphenytoin
Severe
How does the drug interact with Kezlin 150Mg Inj 2Ml:
When Kezlin 150Mg Inj 2Ml is taken with Fosphenytoin, it can cause the body to process Kezlin 150Mg Inj 2Ml faster.

How to manage the interaction:
Although there is a possible interaction between Kezlin 150Mg Inj 2Ml and Fosphenytoin, you can take these medicines together if prescribed by your doctor. If you notice any symptoms like sudden drowsiness, fatigue, confusion, itching, burning, or tingling sensation, abnormal body movements, or loss of coordination, make sure to contact your doctor right away. Do not stop using any medications without first talking to your doctor.
ClindamycinGentamicin
Severe
How does the drug interact with Kezlin 150Mg Inj 2Ml:
Co-administration of of Kezlin 150Mg Inj 2Ml with gentamicin may increase the risk of kidney and/or nerve damage.

How to manage the interaction:
Although there is a possible interaction, Kezlin 150Mg Inj 2Ml can be taken with gentamicin if prescribed by the doctor. Consult the prescriber if you experience signs and symptoms of kidney damage such as sudden weight gain or weight loss, nausea, vomiting, fluid retention, loss of appetite, increased or decreased urination, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. If you develop diarrhea or vomiting during treatment with these medications, drink plenty of fluids to prevent dehydration, as dehydration may also harm the kidney.
ClindamycinBoceprevir
Severe
How does the drug interact with Kezlin 150Mg Inj 2Ml:
Co-administration of Boceprevir together with Kezlin 150Mg Inj 2Ml can increase the effects of Kezlin 150Mg Inj 2Ml.

How to manage the interaction:
Although there is a possible interaction between Kezlin 150Mg Inj 2Ml and Boceprevir, you can take these medicines together if prescribed by your doctor. If you have ongoing feelings of sickness, throwing up, having loose stools, or pain in your stomach, it's important to contact your doctor right away. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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CLINDAMYCIN-150MGOther bacterial intestinal infections
Severe
CLINDAMYCIN-150MGDisorders related to short gestation and low birth weight, not elsewhere classified
Severe

Drug-Diseases Interactions

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CLINDAMYCIN-150MGOther bacterial intestinal infections
Severe
How does the disease interact with Kezlin 150Mg Inj 2Ml:
Almost all antibacterial medications have been associated with reports of Clostridioides difficile-associated diarrhoea (CDAD), formerly known as pseudomembranous colitis. It can vary from mild diarrhoea to deadly colitis.

How to manage the interaction:
Clostridioides difficile-associated diarrhea (CDAD) ranging from mild diarrhoea to colitis has been reported during treatment with antibacterial agents. Therapy should be administered cautiously in patients with history of gastrointestinal disease, particularly colitis and pseudomembranous colitis. Appropriate fluid and electrolyte management, protein supplementation, and antibacterial treatment of C difficile is advised.
CLINDAMYCIN-150MGDisorders related to short gestation and low birth weight, not elsewhere classified
Severe
How does the disease interact with Kezlin 150Mg Inj 2Ml:
Benzyl alcohol is frequently used as a preservative in the formulation of multidose vials for parenteral medicines. Manufacturers of pharmaceuticals believe that using them in neonates, especially preterm and underweight newborns, is contraindicated. In low birth weight preterm newborns, the use of benzyl alcohol in bacteriostatic saline intravascular flush and endotracheal tube lavage solutions has been linked to mortality and serious respiratory and metabolic problems.

How to manage the interaction:
Parenteral medications containing benzyl alcohol as a preservative are contraindicated in neonates, particularly premature infants and infants of low birth weight.
CLINDAMYCIN-150MGOther diseases of liver
Moderate
How does the disease interact with Kezlin 150Mg Inj 2Ml:
The liver is the primary site of Kezlin 150Mg Inj 2Ml metabolism. Patients with significantly impaired hepatic function may have a rise in the blood concentration of Kezlin 150Mg Inj 2Ml and a prolongation of the half-life. Additionally, the drug's usage may result in abnormal liver enzyme levels and jaundice. Patients with liver problems should receive Kezlin 150Mg Inj 2Ml therapy with caution. When given every 8 hours, dosage modifications might not be required. However, with high-dose therapy, serum concentrations should be observed, and during prolonged therapy, regular liver function tests should be carried out.

How to manage the interaction:
Kezlin 150Mg Inj 2Ml is primarily metabolized by the liver. Therapy with Kezlin 150Mg Inj 2Ml should be administered cautiously in patients with liver disease. Serum concentrations should be monitored during high-dose therapy, and periodic liver function tests should be performed during prolonged therapy.
CLINDAMYCIN-150MGOther disorders of kidney and ureter, not elsewhere classified
Moderate
How does the disease interact with Kezlin 150Mg Inj 2Ml:
Kezlin 150Mg Inj 2Ml is partially removed by the kidney. Kezlin 150Mg Inj 2Ml should be used with caution in individuals with significantly impaired renal function. Dosage changes are probably to be required. Serum Kezlin 150Mg Inj 2Ml concentrations should be monitored throughout high-dose therapy, and renal function tests should be conducted on a regular basis during extended medication.

How to manage the interaction:
Therapy with Kezlin 150Mg Inj 2Ml should be administered cautiously in patients with severely impaired renal function. Serum Kezlin 150Mg Inj 2Ml concentrations should be monitored during high-dose therapy, and periodic renal function tests should be performed during prolonged therapy.
CLINDAMYCIN-150MGOther disorders of kidney and ureter, not elsewhere classified
Moderate
How does the disease interact with Kezlin 150Mg Inj 2Ml:
Kezlin 150Mg Inj 2Ml is partially removed by the kidney. Kezlin 150Mg Inj 2Ml should be used with caution in individuals with significantly impaired renal function. Dosage changes are probably to be required. Serum Kezlin 150Mg Inj 2Ml concentrations should be monitored throughout high-dose therapy, and renal function tests should be conducted on a regular basis during extended medication.

How to manage the interaction:
Therapy with Kezlin 150Mg Inj 2Ml should be administered cautiously in patients with severely impaired renal function. Serum Kezlin 150Mg Inj 2Ml concentrations should be monitored during high-dose therapy, and periodic renal function tests should be performed during prolonged therapy.

Drug-Drug Interactions Checker List

  • ERYTHROMYCIN
  • RIFAMPIN
  • ATRACURIUM
  • VECURONIUM

Diet & Lifestyle Advise

  • Wash your hands often to maintain cleanliness.
  • Avoid sharing personal items like shaving razors.
  • Include whole-grain foods like multigrain bread and brown rice in your diet. 
  • Taking probiotics after an antibiotic treatment reduces the risk of antibiotic-associated diarrhoea. 
  • Try taking yoghurt, cheese, sauerkraut, and kimchi that help restore the intestine's good bacteria.
  • Include more fibre-enriched food in your diet that is easily digested by your gut bacteria. Fibre foods may also help restore healthy gut bacteria after a course of antibiotics. 
  • Avoid intake of alcoholic beverages as it may cause dehydration and affect your sleep. 
  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep. 

Habit Forming

No

Special Advise

  • Liver and kidney function monitoring (Liver and kidney function tests) are recommended in patients with severe liver and kidney diseases.
  • Clostridium difficile-associated diarrhoea (CDAD) is reported during the usage of antibiotics. Please consult your doctor if you experience prolonged diarrhoea.

Author Details

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Disease/Condition Glossary

Bacterial infection: It occurs when harmful bacteria grow in the body and causes illness. It can infect any part of the body and multiply very quickly. Bacteria may be gram-positive (have a thick cell wall) or gram-negative (do not have a cell wall). Some common symptoms of a bacterial infection include cough, fever, shortness of breath, chills, muscle pain, fatigue, and tiredness. Untreated bacterial infections may lead to serious life-threatening conditions like sepsis.

Kezlin 150Mg Inj 2Ml Substitute

Substitutes safety advice
  • Dalacin C 150 Capsule 10's

    15.44per tablet
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    12.17per tablet
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    24.30per tablet
  • Clindum-300Mg/2Ml Injection

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  • Kezlin 150mg Injection 4ml

    by AYUR

    57.27per tablet
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