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Composition :
CLINDAMYCIN-150MG
Manufacturer/Marketer :
Alkem Laboratories Ltd
Consume Type :
PARENTERAL
Return Policy :
Not Returnable
Expires on or after :
Drug-Drug Interactions
Severe
Severe
Drug-Drug Interactions
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Severe
How does the drug interact with Kezlin 150Mg Inj 2Ml:
Co-administration of Kezlin 150Mg Inj 2Ml with Balsalazide may reduce the effectiveness of Balsalazide.
How to manage the interaction:
Although there is a possible interaction, Kezlin 150Mg Inj 2Ml can be taken with balsalazide if prescribed by the doctor. Consult the prescriber if you have any concerns, the doctor may prescribe alternatives that do not interact, dose adjustment, or more frequent monitoring to safely use both medications. Do not discontinue the medication without consulting a doctor.
Co-administration of Kezlin 150Mg Inj 2Ml with Balsalazide may reduce the effectiveness of Balsalazide.
How to manage the interaction:
Although there is a possible interaction, Kezlin 150Mg Inj 2Ml can be taken with balsalazide if prescribed by the doctor. Consult the prescriber if you have any concerns, the doctor may prescribe alternatives that do not interact, dose adjustment, or more frequent monitoring to safely use both medications. Do not discontinue the medication without consulting a doctor.
Severe
How does the drug interact with Kezlin 150Mg Inj 2Ml:
Co-administration of of Kezlin 150Mg Inj 2Ml with gentamicin may increase the risk of kidney and/or nerve damage.
How to manage the interaction:
Although there is a possible interaction, Kezlin 150Mg Inj 2Ml can be taken with gentamicin if prescribed by the doctor. Consult the prescriber if you experience signs and symptoms of kidney damage such as sudden weight gain or weight loss, nausea, vomiting, fluid retention, loss of appetite, increased or decreased urination, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. If you develop diarrhea or vomiting during treatment with these medications, drink plenty of fluids to prevent dehydration, as dehydration may also harm the kidney.
Co-administration of of Kezlin 150Mg Inj 2Ml with gentamicin may increase the risk of kidney and/or nerve damage.
How to manage the interaction:
Although there is a possible interaction, Kezlin 150Mg Inj 2Ml can be taken with gentamicin if prescribed by the doctor. Consult the prescriber if you experience signs and symptoms of kidney damage such as sudden weight gain or weight loss, nausea, vomiting, fluid retention, loss of appetite, increased or decreased urination, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. If you develop diarrhea or vomiting during treatment with these medications, drink plenty of fluids to prevent dehydration, as dehydration may also harm the kidney.
ClindamycinBacitracin
Severe
How does the drug interact with Kezlin 150Mg Inj 2Ml:
Co-administration of Kezlin 150Mg Inj 2Ml with Bacitracin may increase the risk of kidney and/or nerve damage.
How to manage the interaction:
Although there is a possible interaction, Kezlin 150Mg Inj 2Ml can be taken with bacitracin if prescribed by the doctor. Consult the prescriber if you experience signs and symptoms of kidney damage such as sudden weight gain or weight loss, nausea, vomiting, fluid retention, loss of appetite, increased or decreased urination, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Let your doctor know if you develop seizures; hearing problems; or numbness, burning or tingling in your hands and feet. If you develop diarrhoea or vomiting during treatment with these medications, drink plenty of fluids to prevent dehydration, as dehydration may harm the kidney.
Co-administration of Kezlin 150Mg Inj 2Ml with Bacitracin may increase the risk of kidney and/or nerve damage.
How to manage the interaction:
Although there is a possible interaction, Kezlin 150Mg Inj 2Ml can be taken with bacitracin if prescribed by the doctor. Consult the prescriber if you experience signs and symptoms of kidney damage such as sudden weight gain or weight loss, nausea, vomiting, fluid retention, loss of appetite, increased or decreased urination, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Let your doctor know if you develop seizures; hearing problems; or numbness, burning or tingling in your hands and feet. If you develop diarrhoea or vomiting during treatment with these medications, drink plenty of fluids to prevent dehydration, as dehydration may harm the kidney.
ClindamycinCholera, live attenuated
Severe
How does the drug interact with Kezlin 150Mg Inj 2Ml:
Co-administration of Kezlin 150Mg Inj 2Ml may reduce the activity of the cholera vaccine.
How to manage the interaction:
Talk to your doctor before receiving the Cholera vaccine if you are currently being treated with Kezlin 150Mg Inj 2Ml or have been treated within the last 14 days. To ensure adequate vaccine response, you should not receive cholera vaccine until at least 14 days after you complete antibiotic therapy. Do not discontinue the medication without consulting a doctor.
Co-administration of Kezlin 150Mg Inj 2Ml may reduce the activity of the cholera vaccine.
How to manage the interaction:
Talk to your doctor before receiving the Cholera vaccine if you are currently being treated with Kezlin 150Mg Inj 2Ml or have been treated within the last 14 days. To ensure adequate vaccine response, you should not receive cholera vaccine until at least 14 days after you complete antibiotic therapy. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Kezlin 150Mg Inj 2Ml:
Taking Kezlin 150Mg Inj 2Ml with Botulinum toxin can increase the risk or severity of side effects.
How to manage the interaction:
Taking Kezlin 150Mg Inj 2Ml with Botulinum toxin together can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Taking Kezlin 150Mg Inj 2Ml with Botulinum toxin can increase the risk or severity of side effects.
How to manage the interaction:
Taking Kezlin 150Mg Inj 2Ml with Botulinum toxin together can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ClindamycinAmprenavir
Severe
How does the drug interact with Kezlin 150Mg Inj 2Ml:
Co-administration of Amprenavir together with Kezlin 150Mg Inj 2Ml can increase the effects of Kezlin 150Mg Inj 2Ml.
How to manage the interaction:
Co-administration of Kezlin 150Mg Inj 2Ml with Amprenavir can possibly result in an interaction, but it can be taken if a doctor has advised it. If you have ongoing feelings of sickness, throwing up, having loose stools, or pain in your stomach, it's important to contact your doctor right away. Do not stop using any medications without talking to a doctor.
Co-administration of Amprenavir together with Kezlin 150Mg Inj 2Ml can increase the effects of Kezlin 150Mg Inj 2Ml.
How to manage the interaction:
Co-administration of Kezlin 150Mg Inj 2Ml with Amprenavir can possibly result in an interaction, but it can be taken if a doctor has advised it. If you have ongoing feelings of sickness, throwing up, having loose stools, or pain in your stomach, it's important to contact your doctor right away. Do not stop using any medications without talking to a doctor.
How does the drug interact with Kezlin 150Mg Inj 2Ml:
Taking Kezlin 150Mg Inj 2Ml with clarithromycin may increase the effects of Kezlin 150Mg Inj 2Ml.
How to manage the interaction:
Although there is a possible interaction, Kezlin 150Mg Inj 2Ml can be taken with clarithromycin if prescribed by the doctor. Consult the prescriber if you experience persistent vomiting, nausea, abdominal pain, or diarrhea. Do not discontinue the medication without consulting a doctor.
Taking Kezlin 150Mg Inj 2Ml with clarithromycin may increase the effects of Kezlin 150Mg Inj 2Ml.
How to manage the interaction:
Although there is a possible interaction, Kezlin 150Mg Inj 2Ml can be taken with clarithromycin if prescribed by the doctor. Consult the prescriber if you experience persistent vomiting, nausea, abdominal pain, or diarrhea. Do not discontinue the medication without consulting a doctor.
Severe
How does the drug interact with Kezlin 150Mg Inj 2Ml:
Concomitant use of Kezlin 150Mg Inj 2Ml with ceritinib can increase the effects of Kezlin 150Mg Inj 2Ml
How to manage the interaction:
Although there is a possible interaction, Kezlin 150Mg Inj 2Ml can be taken with ceritinib if prescribed by the doctor. Consult the prescriber if you experience persistent vomiting, nausea, abdominal pain, or diarrhoea.
Concomitant use of Kezlin 150Mg Inj 2Ml with ceritinib can increase the effects of Kezlin 150Mg Inj 2Ml
How to manage the interaction:
Although there is a possible interaction, Kezlin 150Mg Inj 2Ml can be taken with ceritinib if prescribed by the doctor. Consult the prescriber if you experience persistent vomiting, nausea, abdominal pain, or diarrhoea.
Severe
How does the drug interact with Kezlin 150Mg Inj 2Ml:
Coadministration of use of Kezlin 150Mg Inj 2Ml with ketoconazole can increase the effects of Kezlin 150Mg Inj 2Ml.
How to manage the interaction:
Although there is a possible interaction, Kezlin 150Mg Inj 2Ml can be taken with ketoconazole if prescribed by the doctor. Consult the prescriber if you experience persistent vomiting, nausea, abdominal pain or diarrhea. Do not discontinue any medication without consulting a doctor. Do not discontinue any medication without consulting a doctor.
Coadministration of use of Kezlin 150Mg Inj 2Ml with ketoconazole can increase the effects of Kezlin 150Mg Inj 2Ml.
How to manage the interaction:
Although there is a possible interaction, Kezlin 150Mg Inj 2Ml can be taken with ketoconazole if prescribed by the doctor. Consult the prescriber if you experience persistent vomiting, nausea, abdominal pain or diarrhea. Do not discontinue any medication without consulting a doctor. Do not discontinue any medication without consulting a doctor.
Severe
How does the drug interact with Kezlin 150Mg Inj 2Ml:
Co-administration of Capreomycin with Kezlin 150Mg Inj 2Ml can increase the risk of kidney or nerve damage.
How to manage the interaction:
There may be a possibility of interaction between Kezlin 150Mg Inj 2Ml and Capreomycin, but it can be taken if prescribed by a doctor. Do not discontinue any medications without first consulting your doctor.
Co-administration of Capreomycin with Kezlin 150Mg Inj 2Ml can increase the risk of kidney or nerve damage.
How to manage the interaction:
There may be a possibility of interaction between Kezlin 150Mg Inj 2Ml and Capreomycin, but it can be taken if prescribed by a doctor. Do not discontinue any medications without first consulting your doctor.
Drug-Food Interactions
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.
Drug-Food Interactions
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Product Substitutes
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Drug-Diseases Interactions
CLINDAMYCIN-150MGOther bacterial intestinal infections
Severe
CLINDAMYCIN-150MGDisorders related to short gestation and low birth weight, not elsewhere classified
Severe
Drug-Diseases Interactions
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CLINDAMYCIN-150MGOther bacterial intestinal infections
Severe
How does the disease interact with Kezlin 150Mg Inj 2Ml:
Almost all antibacterial medications have been associated with reports of Clostridioides difficile-associated diarrhoea (CDAD), formerly known as pseudomembranous colitis. It can vary from mild diarrhoea to deadly colitis.
How to manage the interaction:
Clostridioides difficile-associated diarrhea (CDAD) ranging from mild diarrhoea to colitis has been reported during treatment with antibacterial agents. Therapy should be administered cautiously in patients with history of gastrointestinal disease, particularly colitis and pseudomembranous colitis. Appropriate fluid and electrolyte management, protein supplementation, and antibacterial treatment of C difficile is advised.
Almost all antibacterial medications have been associated with reports of Clostridioides difficile-associated diarrhoea (CDAD), formerly known as pseudomembranous colitis. It can vary from mild diarrhoea to deadly colitis.
How to manage the interaction:
Clostridioides difficile-associated diarrhea (CDAD) ranging from mild diarrhoea to colitis has been reported during treatment with antibacterial agents. Therapy should be administered cautiously in patients with history of gastrointestinal disease, particularly colitis and pseudomembranous colitis. Appropriate fluid and electrolyte management, protein supplementation, and antibacterial treatment of C difficile is advised.
CLINDAMYCIN-150MGDisorders related to short gestation and low birth weight, not elsewhere classified
Severe
How does the disease interact with Kezlin 150Mg Inj 2Ml:
Benzyl alcohol is frequently used as a preservative in the formulation of multidose vials for parenteral medicines. Manufacturers of pharmaceuticals believe that using them in neonates, especially preterm and underweight newborns, is contraindicated. In low birth weight preterm newborns, the use of benzyl alcohol in bacteriostatic saline intravascular flush and endotracheal tube lavage solutions has been linked to mortality and serious respiratory and metabolic problems.
How to manage the interaction:
Parenteral medications containing benzyl alcohol as a preservative are contraindicated in neonates, particularly premature infants and infants of low birth weight.
Benzyl alcohol is frequently used as a preservative in the formulation of multidose vials for parenteral medicines. Manufacturers of pharmaceuticals believe that using them in neonates, especially preterm and underweight newborns, is contraindicated. In low birth weight preterm newborns, the use of benzyl alcohol in bacteriostatic saline intravascular flush and endotracheal tube lavage solutions has been linked to mortality and serious respiratory and metabolic problems.
How to manage the interaction:
Parenteral medications containing benzyl alcohol as a preservative are contraindicated in neonates, particularly premature infants and infants of low birth weight.
CLINDAMYCIN-150MGOther diseases of liver
Moderate
How does the disease interact with Kezlin 150Mg Inj 2Ml:
The liver is the primary site of Kezlin 150Mg Inj 2Ml metabolism. Patients with significantly impaired hepatic function may have a rise in the blood concentration of Kezlin 150Mg Inj 2Ml and a prolongation of the half-life. Additionally, the drug's usage may result in abnormal liver enzyme levels and jaundice. Patients with liver problems should receive Kezlin 150Mg Inj 2Ml therapy with caution. When given every 8 hours, dosage modifications might not be required. However, with high-dose therapy, serum concentrations should be observed, and during prolonged therapy, regular liver function tests should be carried out.
How to manage the interaction:
Kezlin 150Mg Inj 2Ml is primarily metabolized by the liver. Therapy with Kezlin 150Mg Inj 2Ml should be administered cautiously in patients with liver disease. Serum concentrations should be monitored during high-dose therapy, and periodic liver function tests should be performed during prolonged therapy.
The liver is the primary site of Kezlin 150Mg Inj 2Ml metabolism. Patients with significantly impaired hepatic function may have a rise in the blood concentration of Kezlin 150Mg Inj 2Ml and a prolongation of the half-life. Additionally, the drug's usage may result in abnormal liver enzyme levels and jaundice. Patients with liver problems should receive Kezlin 150Mg Inj 2Ml therapy with caution. When given every 8 hours, dosage modifications might not be required. However, with high-dose therapy, serum concentrations should be observed, and during prolonged therapy, regular liver function tests should be carried out.
How to manage the interaction:
Kezlin 150Mg Inj 2Ml is primarily metabolized by the liver. Therapy with Kezlin 150Mg Inj 2Ml should be administered cautiously in patients with liver disease. Serum concentrations should be monitored during high-dose therapy, and periodic liver function tests should be performed during prolonged therapy.
CLINDAMYCIN-150MGOther disorders of kidney and ureter, not elsewhere classified
Moderate
How does the disease interact with Kezlin 150Mg Inj 2Ml:
Kezlin 150Mg Inj 2Ml is partially removed by the kidney. Kezlin 150Mg Inj 2Ml should be used with caution in individuals with significantly impaired renal function. Dosage changes are probably to be required. Serum Kezlin 150Mg Inj 2Ml concentrations should be monitored throughout high-dose therapy, and renal function tests should be conducted on a regular basis during extended medication.
How to manage the interaction:
Therapy with Kezlin 150Mg Inj 2Ml should be administered cautiously in patients with severely impaired renal function. Serum Kezlin 150Mg Inj 2Ml concentrations should be monitored during high-dose therapy, and periodic renal function tests should be performed during prolonged therapy.
Kezlin 150Mg Inj 2Ml is partially removed by the kidney. Kezlin 150Mg Inj 2Ml should be used with caution in individuals with significantly impaired renal function. Dosage changes are probably to be required. Serum Kezlin 150Mg Inj 2Ml concentrations should be monitored throughout high-dose therapy, and renal function tests should be conducted on a regular basis during extended medication.
How to manage the interaction:
Therapy with Kezlin 150Mg Inj 2Ml should be administered cautiously in patients with severely impaired renal function. Serum Kezlin 150Mg Inj 2Ml concentrations should be monitored during high-dose therapy, and periodic renal function tests should be performed during prolonged therapy.
CLINDAMYCIN-150MGOther disorders of kidney and ureter, not elsewhere classified
Moderate
How does the disease interact with Kezlin 150Mg Inj 2Ml:
Kezlin 150Mg Inj 2Ml is partially removed by the kidney. Kezlin 150Mg Inj 2Ml should be used with caution in individuals with significantly impaired renal function. Dosage changes are probably to be required. Serum Kezlin 150Mg Inj 2Ml concentrations should be monitored throughout high-dose therapy, and renal function tests should be conducted on a regular basis during extended medication.
How to manage the interaction:
Therapy with Kezlin 150Mg Inj 2Ml should be administered cautiously in patients with severely impaired renal function. Serum Kezlin 150Mg Inj 2Ml concentrations should be monitored during high-dose therapy, and periodic renal function tests should be performed during prolonged therapy.
Kezlin 150Mg Inj 2Ml is partially removed by the kidney. Kezlin 150Mg Inj 2Ml should be used with caution in individuals with significantly impaired renal function. Dosage changes are probably to be required. Serum Kezlin 150Mg Inj 2Ml concentrations should be monitored throughout high-dose therapy, and renal function tests should be conducted on a regular basis during extended medication.
How to manage the interaction:
Therapy with Kezlin 150Mg Inj 2Ml should be administered cautiously in patients with severely impaired renal function. Serum Kezlin 150Mg Inj 2Ml concentrations should be monitored during high-dose therapy, and periodic renal function tests should be performed during prolonged therapy.
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