Koffel Syrup

Koffel Syrup belongs to a class of medication called 'cough and cold preparations' primarily used to treat dry cough. Coughing (dry or productive) is the body’s way of clearing irritants (like allergens, mucus, or smoke) from airways and preventing infection. There are two types of coughs: dry cough and chesty cough. A dry cough is tickly and doesn't produce any vicious or thick mucus, while a chesty cough (wet cough) means mucous or sputum is produced to help clear your airways. 

Koffel Syrup is a combination of three drugs, namely: Chlorpheniramine maleate (antihistamine), Phenylephrine (decongestant), and Dextromethorphan (cough suppressant). Chlorpheniramine maleate works by blocking the action of histamine, a substance responsible for causing allergic reactions. Phenylephrine helps in shrinking the blood vessels located in the nasal passage, thereby reducing the stuffy nose. Dextromethorphan works by blocking the transmission of nerve signals from the cough center in the brain to the muscles that produce cough. Collectively, it helps to provide relief from dry cough.

Take Koffel Syrup with or without food as advised by your doctor with the help of a measuring cup. Your doctor will recommend how often you take Koffel Syrup based on your medical condition. Some people may experience dry mouth, throat or nose, drowsiness, blurred vision, constipation, dizziness, restlessness, or excitation. Most of these side effects of Koffel Syrup do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Please inform your doctor if you are allergic to Koffel Syrup or any other medicines. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Koffel Syrup. Koffel Syrup is not recommended for children below 12 years of age. If you are about to undergo any medical tests or surgery, please inform your doctor that you are taking Koffel Syrup. Avoid using Koffel Syrup if you have taken medicines such as linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine, and methylene blue injection in the past 14 days. Drink plenty of fluids while taking Koffel Syrup to loosen mucus.

Koffel Syrup contains Chlorpheniramine maleate, Phenylephrine, and Dextromethorphan used to treat dry cough. Chlorpheniramine maleate helps to provide relief from allergy symptoms such as sneezing, running nose, watery eyes, itching, swelling, congestion, or stiffness. Phenylephrine helps in shrinking the blood vessels located in the nasal passage, thereby reducing the stuffy nose. Dextromethorphan works by blocking the transmission of nerve signals from the cough center in the brain to the muscles that produce cough. Thus, Koffel Syrup helps to relieve overall cough, cold and allergic symptoms.

• Dry mouth, throat or nose
• Drowsiness
• Dizziness
• Blurred vision
• Headache
• Constipation
• Restlessness or excitation
• Loss of appetite

Please inform your doctor if you are allergic to Koffel Syrup or any other medicines. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Koffel Syrup. Koffel Syrup is not recommended for children below 4 years of age. If you are about to undergo any medical tests or surgery, please inform your doctor that you are taking Koffel Syrup. Avoid using Koffel Syrup if you have taken medicines such as linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine and methylene blue injection in the past 14 days. Drink plenty of fluids while taking Koffel Syrup to loosen mucus. If you have glaucoma, urinary problems, enlarged prostate, cough with mucus or cough caused by asthma, smoking, chronic bronchitis or emphysema (a lung condition causing shortness of breath), inform your doctor before taking Koffel Syrup.

Drug-Drug Interaction: Koffel Syrup may have interaction with anti-allergic drugs (diphenhydramine), anti-psychotic (escitalopram, desvenlafaxine, vilazodone), pain killer (aspirin), cold medicines (acetaminophen), antibiotics (amoxicillin), anti-depressants (linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine), beta-blockers (metoprolol, atenolol), muscle relaxants (carisoprodol, cyclobenzaprine).

Drug-Food Interaction: Koffel Syrup may interact with alcohol. Therefore, avoid alcohol consumption with Koffel Syrup as it may increase the risk of adverse effects such as drowsiness, dizziness or difficulty in concentrating.

Drug-Disease Interaction: Koffel Syrup is known to interact in patients with liver or kidney disease, asthma, diabetes, glaucoma, cardiovascular diseases, enlarged prostate gland, chronic bronchitis or emphysema (a lung condition causing shortness of breath).

• DIPHENHYDRAMINE
• ESCITALOPRAM
• DESVENLAFAXINE
• VILAZODONE
• ACETAMINOPHEN
• AMOXICILLIN
• LINEZOLID
• PHENELZINE
• SELEGILINE
• RASAGILINE
• ISOCARBOXAZID
• TRANYLCYPROMINE
• METOPROLOL
• ATENOLOL
• CARISOPRODOL
• CYCLOBENZAPRINE
• CETIRIZINE

• Avoid dairy products such as milk, as it may increase mucus production. Also, avoid processed or refined foods to have relief from cough. 
• Drink plenty of fluids to avoid dry throat while you have a cough and loosen mucus.
• Avoid citrus fruits as they may worsen the cough. Eat fruits rich in water content, such as pears, watermelon, peaches and pineapples.

• Do not use Koffel Syrup only to make a child sleepy. 
• Contact a doctor if your symptoms do not improve even after 7 days.
• Contact a doctor immediately if you develop fever, rash or headaches after taking Koffel Syrup. 

Cough: Coughing is the body's way of clearing irritants from the airways (such as allergens, mucus, or smoke) and preventing infection. Coughs can be productive or dry. A productive cough (wet cough) causes sputum (phlegm, mucus, and other matter) to be expelled from the lungs. Coughing is commonly caused by an allergic reaction or a viral infection, but coughing up mucus could indicate a respiratory infection. You may have a bacterial infection in your airways if you cough up thick, solid white mucus. If your mucus is clear or light-coloured, you may have allergies or minor respiratory infections, whereas yellow or green mucus indicates a respiratory infection.