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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

Online payment accepted

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Manufacturer/Marketer :

Nectar Biochem Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Kofradex Junior New Paediatric Orange Flavour Syrup

Kofradex Junior New Paediatric Orange Flavour Syrup belongs to a class of medication called 'cough and cold preparations' primarily used to treat dry cough. Coughing (dry or productive) is the body’s way of clearing irritants (like allergens, mucus, or smoke) from airways and preventing infection. There are two types of coughs: dry cough and chesty cough. A dry cough is tickly and doesn't produce any vicious or thick mucus, while a chesty cough (wet cough) means mucous or sputum is produced to help clear your airways. 

Kofradex Junior New Paediatric Orange Flavour Syrup is a combination of three drugs, namely: Chlorpheniramine maleate (antihistamine), Phenylephrine (decongestant), and Dextromethorphan (cough suppressant). Chlorpheniramine maleate works by blocking the action of histamine, a substance responsible for causing allergic reactions. Phenylephrine helps in shrinking the blood vessels located in the nasal passage, thereby reducing the stuffy nose. Dextromethorphan works by blocking the transmission of nerve signals from the cough center in the brain to the muscles that produce cough. Collectively, it helps to provide relief from dry cough.

Take Kofradex Junior New Paediatric Orange Flavour Syrup with or without food as advised by your doctor with the help of a measuring cup. Your doctor will recommend how often you take Kofradex Junior New Paediatric Orange Flavour Syrup based on your medical condition. Some people may experience dry mouth, throat or nose, drowsiness, blurred vision, constipation, dizziness, restlessness, or excitation. Most of these side effects of Kofradex Junior New Paediatric Orange Flavour Syrup do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Please inform your doctor if you are allergic to Kofradex Junior New Paediatric Orange Flavour Syrup or any other medicines. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Kofradex Junior New Paediatric Orange Flavour Syrup. Kofradex Junior New Paediatric Orange Flavour Syrup is not recommended for children below 12 years of age. If you are about to undergo any medical tests or surgery, please inform your doctor that you are taking Kofradex Junior New Paediatric Orange Flavour Syrup. Avoid using Kofradex Junior New Paediatric Orange Flavour Syrup if you have taken medicines such as linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine, and methylene blue injection in the past 14 days. Drink plenty of fluids while taking Kofradex Junior New Paediatric Orange Flavour Syrup to loosen mucus.

Uses of Kofradex Junior New Paediatric Orange Flavour Syrup

Dry Cough

Directions for Use

Shake the bottle well before use. Check the label for directions and take Kofradex Junior New Paediatric Orange Flavour Syrup with or without food in doses as prescribed by your doctor with the help of a measuring cup provided with the pack.

Medicinal Benefits

Kofradex Junior New Paediatric Orange Flavour Syrup contains Chlorpheniramine maleate, Phenylephrine, and Dextromethorphan used to treat dry cough. Chlorpheniramine maleate helps to provide relief from allergy symptoms such as sneezing, running nose, watery eyes, itching, swelling, congestion, or stiffness. Phenylephrine helps in shrinking the blood vessels located in the nasal passage, thereby reducing the stuffy nose. Dextromethorphan works by blocking the transmission of nerve signals from the cough center in the brain to the muscles that produce cough. Thus, Kofradex Junior New Paediatric Orange Flavour Syrup helps to relieve overall cough, cold and allergic symptoms.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Kofradex Junior New Paediatric Orange Flavour Syrup

  • Dry mouth, throat or nose
  • Drowsiness
  • Dizziness
  • Blurred vision
  • Headache
  • Constipation
  • Restlessness or excitation
  • Loss of appetite

Drug Warnings

Please inform your doctor if you are allergic to Kofradex Junior New Paediatric Orange Flavour Syrup or any other medicines. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Kofradex Junior New Paediatric Orange Flavour Syrup. Kofradex Junior New Paediatric Orange Flavour Syrup is not recommended for children below 4 years of age. If you are about to undergo any medical tests or surgery, please inform your doctor that you are taking Kofradex Junior New Paediatric Orange Flavour Syrup. Avoid using Kofradex Junior New Paediatric Orange Flavour Syrup if you have taken medicines such as linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine and methylene blue injection in the past 14 days. Drink plenty of fluids while taking Kofradex Junior New Paediatric Orange Flavour Syrup to loosen mucus. If you have glaucoma, urinary problems, enlarged prostate, cough with mucus or cough caused by asthma, smoking, chronic bronchitis or emphysema (a lung condition causing shortness of breath), inform your doctor before taking Kofradex Junior New Paediatric Orange Flavour Syrup.

Drug-Drug Interactions

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DextromethorphanPargyline
Critical
DextromethorphanProcarbazine
Critical

Drug-Drug Interactions

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DextromethorphanPargyline
Critical
How does the drug interact with Kofradex Junior New Paediatric Orange Flavour Syrup 60 ml:
Co-administration of Pargyline and Kofradex Junior New Paediatric Orange Flavour Syrup 60 ml can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Kofradex Junior New Paediatric Orange Flavour Syrup 60 ml and Pargyline can lead to an interaction. However, if you experience any symptoms like confusion, hallucination, seizure, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DextromethorphanProcarbazine
Critical
How does the drug interact with Kofradex Junior New Paediatric Orange Flavour Syrup 60 ml:
Co-administration of Kofradex Junior New Paediatric Orange Flavour Syrup 60 ml and Procarbazine may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Procarbazine with Kofradex Junior New Paediatric Orange Flavour Syrup 60 ml can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms - confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering, shaking, blurred vision, muscle spasm, stiffness, incoordination, stomach cramps, nausea, vomiting, or diarrhea - make sure to contact a doctor right away. Do not stop using any medications without talking to a doctor.
DextromethorphanPhenelzine
Critical
How does the drug interact with Kofradex Junior New Paediatric Orange Flavour Syrup 60 ml:
Co-administration of Phenelzine and Kofradex Junior New Paediatric Orange Flavour Syrup 60 ml can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Phenelzine and Kofradex Junior New Paediatric Orange Flavour Syrup 60 ml can lead to an interaction. However, if you experience any symptoms like confusion, hallucination, seizure, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DextromethorphanRasagiline
Critical
How does the drug interact with Kofradex Junior New Paediatric Orange Flavour Syrup 60 ml:
Taking Rasagiline with Kofradex Junior New Paediatric Orange Flavour Syrup 60 ml can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Kofradex Junior New Paediatric Orange Flavour Syrup 60 ml with Rasagiline is not recommended as it can possibly result in an interaction, it can be taken if a doctor has advised it. If you notice any of these symptoms like confusion, hallucination, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, shaking, incoordination, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor. Do not discontinue any medications without consulting a doctor.
DextromethorphanTranylcypromine
Critical
How does the drug interact with Kofradex Junior New Paediatric Orange Flavour Syrup 60 ml:
Taking Tranylcypromine with Kofradex Junior New Paediatric Orange Flavour Syrup 60 ml can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Kofradex Junior New Paediatric Orange Flavour Syrup 60 ml with Tranylcypromine is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fit blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
DextromethorphanIsocarboxazid
Critical
How does the drug interact with Kofradex Junior New Paediatric Orange Flavour Syrup 60 ml:
Co-administration of Isocarboxazid with Kofradex Junior New Paediatric Orange Flavour Syrup 60 ml can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Taking Kofradex Junior New Paediatric Orange Flavour Syrup 60 ml and Isocarboxazid can lead to an interaction. However, if you experience any symptoms like confusion, hallucination, seizure, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DextromethorphanSelegiline
Critical
How does the drug interact with Kofradex Junior New Paediatric Orange Flavour Syrup 60 ml:
Co-administration of Kofradex Junior New Paediatric Orange Flavour Syrup 60 ml and Selegiline may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Selegiline with Kofradex Junior New Paediatric Orange Flavour Syrup 60 ml can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms - confusion, hallucination, fits, increased heart rate, fever, excessive sweating, shivering, shaking, blurred vision, muscle spasm, stiffness, incoordination, stomach cramps, nausea, vomiting, or diarrhea - make sure to contact a doctor right away. Do not stop using any medications without talking to a doctor.
PhenylephrineSevoflurane
Critical
How does the drug interact with Kofradex Junior New Paediatric Orange Flavour Syrup 60 ml:
Co-administration of Kofradex Junior New Paediatric Orange Flavour Syrup 60 ml with Sevoflurane can increase the levels of Kofradex Junior New Paediatric Orange Flavour Syrup 60 ml and lead to side effects.

How to manage the interaction:
Taking Kofradex Junior New Paediatric Orange Flavour Syrup 60 ml with Sevoflurane is not recommended, it can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.
PhenylephrinePropofol
Critical
How does the drug interact with Kofradex Junior New Paediatric Orange Flavour Syrup 60 ml:
Taking Kofradex Junior New Paediatric Orange Flavour Syrup 60 ml with Propofol may lead to increased levels of Kofradex Junior New Paediatric Orange Flavour Syrup 60 ml leading to side effects like high blood pressure.

How to manage the interaction:
Taking Kofradex Junior New Paediatric Orange Flavour Syrup 60 ml with Propofol is not recommended, but it can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.
PhenylephrineTranylcypromine
Critical
How does the drug interact with Kofradex Junior New Paediatric Orange Flavour Syrup 60 ml:
Taking Tranylcypromine with Kofradex Junior New Paediatric Orange Flavour Syrup 60 ml can increase the risk of high blood pressure.

How to manage the interaction:
Taking Tranylcypromine with Kofradex Junior New Paediatric Orange Flavour Syrup 60 ml is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and fainting Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid dairy products such as milk, as it may increase mucus production. Also, avoid processed or refined foods to have relief from cough. 
  • Drink plenty of fluids to avoid dry throat while you have a cough and loosen mucus.
  • Avoid citrus fruits as they may worsen the cough. Eat fruits rich in water content, such as pears, watermelon, peaches and pineapples.

Habit Forming

No

Therapeutic Class

COUGH AND COLD PREPARATIONS

Kofradex Junior New Paediatric Orange Flavour Syrup Substitute

Substitutes safety advice
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  • Tusq-DX Tablet 10's

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  • Bericoff-D Syrup 100 ml

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    0.96per tablet
  • Brozy D Syrup 100 ml

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  • Drycof Syrup 60 ml

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Author Details

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Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Kofradex Junior New Paediatric Orange Flavour Syrup contains Chlorpheniramine maleate, Phenylephrine, and Dextromethorphan. Chlorpheniramine works by blocking the action of histamine, a substance responsible for causing allergic reactions. Phenylephrine is a 'decongestant' that helps in shrinking the blood vessels located in the nasal passage, thereby reducing stuffy nose. Dextromethorphan works by blocking the transmission of nerve signals from the cough center in the brain to the muscles that produce cough.

No, you should not take Kofradex Junior New Paediatric Orange Flavour Syrup if you need to undergo surgery as it may lead to excessive drowsiness and sleepiness when given along with anaesthesia. Therefore, if you are about to undergo any surgery, please inform your doctor that you are taking Kofradex Junior New Paediatric Orange Flavour Syrup. Your doctor may advise you to stop taking Kofradex Junior New Paediatric Orange Flavour Syrup 72 hours before the surgery.

It is not recommended to take Kofradex Junior New Paediatric Orange Flavour Syrup along with any anti-depressant medication, especially MAO inhibitors (linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine), as it may lead to unpleasant side-effects or any drug interaction. Also, Kofradex Junior New Paediatric Orange Flavour Syrup should be taken at least 15 days after your last dose of anti-depressants.

Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take Kofradex Junior New Paediatric Orange Flavour Syrup and skip the missed dose. Do not take extra medicine to make up for the missed dose.

Kofradex Junior New Paediatric Orange Flavour Syrup should be used with caution and only when prescribed by a doctor in patients with glaucoma, as Kofradex Junior New Paediatric Orange Flavour Syrup may rarely worsen the symptoms of glaucoma.

Drug-Drug Interactions Checker List

  • DIPHENHYDRAMINE
  • ESCITALOPRAM
  • DESVENLAFAXINE
  • VILAZODONE
  • ACETAMINOPHEN
  • AMOXICILLIN
  • LINEZOLID
  • PHENELZINE
  • SELEGILINE
  • RASAGILINE
  • ISOCARBOXAZID
  • TRANYLCYPROMINE
  • METOPROLOL
  • ATENOLOL
  • CARISOPRODOL
  • CYCLOBENZAPRINE
  • CETIRIZINE

Special Advise

  • Do not use Kofradex Junior New Paediatric Orange Flavour Syrup only to make a child sleepy. 
  • Contact a doctor if your symptoms do not improve even after 7 days.
  • Contact a doctor immediately if you develop fever, rash or headaches after taking Kofradex Junior New Paediatric Orange Flavour Syrup. 

Disease/Condition Glossary

Cough: Coughing is the body's way of clearing irritants from the airways (such as allergens, mucus, or smoke) and preventing infection. Coughs can be productive or dry. A productive cough (wet cough) causes sputum (phlegm, mucus, and other matter) to be expelled from the lungs. Coughing is commonly caused by an allergic reaction or a viral infection, but coughing up mucus could indicate a respiratory infection. You may have a bacterial infection in your airways if you cough up thick, solid white mucus. If your mucus is clear or light-coloured, you may have allergies or minor respiratory infections, whereas yellow or green mucus indicates a respiratory infection.

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