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Written By Divya L , PharmaD
Reviewed By Veda Maddala , M Pharmacy
Non returnable*
COD available

Online payment accepted

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Manufacturer/Marketer

Ipca Laboratories Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About Lariago Injection 5 ml

Lariago Injection 5 ml belongs to the class of 'anti-malarial drugs', primarily used to treat and prevent malaria. It may also be used to treat extraintestinal amebiasis/amoebiasis. Malaria is a disease caused by a plasmodium parasite transmitted by the bite of infected Anopheles mosquitoes. When an infected mosquito bites a healthy person, it transmits the 'Plasmodium parasite' into the bloodstream, which affects the red blood cells and liver cells. Extraintestinal amebiasis is a parasitic infection caused by Entamoeba histolytica that spreads to various organs, most commonly the liver.

Lariago Injection 5 ml contains Chloroquine. It works by increasing the concentration of a toxic compound in the parasite that leads to its death. It is also amoebicidal in action and destroys the parasitic amoebas causing amoebiasis. Thereby treats malaria ans extraintestinal amebiasis.

Your doctor will decide the dose and duration based on your medical condition. Common side effects of Lariago Injection 5 ml include nausea, vomiting, diarrhoea, stomach cramps, headache, hair loss, changes in mood/confusion, vision changes/blurred vision, black or tarry stools, bleeding gums, and dizziness. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Let your doctor know if you are allergic to any of the components in Lariago Injection 5 ml. Inform your doctor if you have any liver or kidney problems, fits, heart diseases, hearing problems, vision-related issues, fits, and damaged retina or vision problems before starting Lariago Injection 5 ml. It is essential to let your doctor know if you are pregnant, planning to conceive, or are a breastfeeding mother. Lariago Injection 5 ml may cause dizziness; hence do not drive or operate machinery until you are alert. Avoiding alcohol during the treatment is recommended to rule out any possibility of worsening side effects. Lariago Injection 5 ml should be used for children only when prescribed by a doctor.

Uses of Lariago Injection 5 ml

Malaria and Extraintestinal Amebiasis.

Directions for Use

Lariago Injection 5 ml will be injected by a healthcare professional. Do not self-administer.

Medicinal Benefits

Lariago Injection 5 ml contains Chloroquine. It works by increasing the concentration of a toxic compound in the parasite that leads to its death. It is effective against parasitic species, including Plasmodium vivax, Plasmodium malariae, and susceptible strains of Plasmodium falciparum. Lariago Injection 5 ml is useful in extending the interval between treatment and relapse in patients with malaria or vivax malaria. It is also amoebicidal in action and destroys the parasitic amoebas causing amoebiasis. Chloroquine also has off-label uses in treating autoimmune diseases, such as rheumatoid arthritis and systemic lupus erythematosus.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Lariago Injection 5 ml

  • Nausea 
  • Vomiting 
  • Diarrhoea 
  • Stomach cramps 
  • Headache 
  • Hair loss 
  • Changes in mood/confusion 
  • Vision changes/blurred vision 
  • Black or tarry stools 
  • Bleeding gums 
  • Dizziness 

Drug Warnings

Before using Lariago Injection 5 ml, inform your doctor if you have recently used any prescription and non-prescription medications, including other anti-malarial drugs. Inform your doctor if you have any allergic reactions, liver or kidney problems, heart diseases, diabetes, G-6-PD (glucose-6 phosphate dehydrogenase) deficiency, electrolyte imbalance, psoriasis, alcoholism, porphyria, hearing problems, vision-related issues, fits, and damaged retina or vision problems. Please seek medical advice if you are pregnant or breastfeeding before taking Lariago Injection 5 ml. This medicine may cause dizziness; hence drive or operate machinery only when you are alert. Do not consume alcohol while being treated with Lariago Injection 5 ml.

Drug-Drug Interactions

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ChloroquineCisapride
Critical
ChloroquineThioridazine
Critical

Drug-Drug Interactions

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ChloroquineCisapride
Critical
How does the drug interact with Lariago Injection 5 ml:
Taking Lariago Injection 5 ml with Cisapride can increase the risk of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Lariago Injection 5 ml with Cisapride is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately.
ChloroquineThioridazine
Critical
How does the drug interact with Lariago Injection 5 ml:
When Thioridazine and Lariago Injection 5 ml are taken together, can increase the chance of a serious abnormal heart rhythm

How to manage the interaction:
Taking Lariago Injection 5 ml with Thioridazine is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
ChloroquineAgalsidase beta
Critical
How does the drug interact with Lariago Injection 5 ml:
Using Lariago Injection 5 ml with Agalsidase beta can reduce the effectiveness of agalsidase beta.

How to manage the interaction:
Taking Agalsidase beta with Lariago Injection 5 ml is not recommended, but can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
ChloroquineZiprasidone
Critical
How does the drug interact with Lariago Injection 5 ml:
Taking Lariago Injection 5 ml with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Lariago Injection 5 ml with Ziprasidone is not recommended, it can be taken together if prescribed by a doctor. However, consult a doctor if you experience dizziness, drowsiness, confusion, and difficulty concentrating. Do not discontinue any medications without consulting a doctor.
ChloroquineMesoridazine
Critical
How does the drug interact with Lariago Injection 5 ml:
Taking Lariago Injection 5 ml with Mesoridazine together can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Lariago Injection 5 ml with Mesoridazine is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
ChloroquineAgalsidase alfa
Critical
How does the drug interact with Lariago Injection 5 ml:
When Agalsidase alfa is used with Lariago Injection 5 ml, it may decrease the effectiveness of the Agalsidase alfa.

How to manage the interaction:
Taking Agalsidase alfa with Lariago Injection 5 ml is not recommended, it can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not stop using any medications without talking to a doctor.
ChloroquineAurothioglucose
Critical
How does the drug interact with Lariago Injection 5 ml:
Taking Aurothioglucose with Lariago Injection 5 ml can cause blood disorders and other severe side effects

How to manage the interaction:
Taking Aurothioglucose with Lariago Injection 5 ml is not recommended, as it can cause an interaction, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience unusual symptoms. Do not discontinue any medications without consulting a doctor.
ChloroquineBepridil
Critical
How does the drug interact with Lariago Injection 5 ml:
Using Lariago Injection 5 ml together with bepridil can increase the risk of an irregular heart rhythm

How to manage the interaction:
Taking Lariago Injection 5 ml with Bepridil is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately.
ChloroquineSaquinavir
Critical
How does the drug interact with Lariago Injection 5 ml:
Using saquinavir together with Lariago Injection 5 ml can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Lariago Injection 5 ml with Saquinavir is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
ChloroquinePimozide
Critical
How does the drug interact with Lariago Injection 5 ml:
When Pimozide and Lariago Injection 5 ml are taken together, it can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Lariago Injection 5 ml with Pimozide is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Malaria:

  • Take nutritious food, including fresh fruits and vegetables, to help recover from malarial fever.
  • During malarial fever, the patient may experience appetite loss. In such cases, drink glucose water, fresh fruit juices, and coconut water.
  • Include high-fibre foods like green leafy vegetables and fruits to aid digestion.
  • Take proper rest to help your body relax and heal faster.
  • Avoid or limit the intake of alcohol and caffeine.

Extra intestinal Amebiasis:

  • Include fruits, vegetables, whole-grain bread, low-fat dairy products, beans, lean meats, and fish in your diet.
  • Avoid alcohol consumption that can further damage your liver in liver abscess.
  • Wash your hands often to prevent infection.
  • Stay away from patients who are infected with amebiasis.

Habit Forming

No

Therapeutic Class

ANTI- MALARIALS

Author Details

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Drug-Diseases Interactions

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CHLOROQUINE-64.5MGDisorders of porphyrin and bilirubin metabolism
Severe
CHLOROQUINE-64.5MGOther cardiac arrhythmias
Moderate

Drug-Diseases Interactions

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CHLOROQUINE-64.5MGDisorders of porphyrin and bilirubin metabolism
Severe
How does the disease interact with Lariago Injection 5 ml:
Porphyria: In porphyria the use of Lariago Injection 5 ml may aggravate this condition. Avoid Lariago Injection 5 ml use until it is required.

How to manage the interaction:
If the risks aren't expected to outweigh the possible advantages, Lariago Injection 5 ml shouldn't be utilized on these patients.
CHLOROQUINE-64.5MGOther cardiac arrhythmias
Moderate
How does the disease interact with Lariago Injection 5 ml:
Arrhythmias:Lariago Injection 5 ml has adverse effect like prolongation of QT interval, ventricular arrhythmias and torsades de pointes. Monitor ECG before initiation and during the therapy.

How to manage the interaction:
If you have sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat while taking these medications, whether they are taken together or separately, you should seek immediate assistance from a doctor. A close monitoring of ECG is required.
CHLOROQUINE-64.5MGEpilepsy
Moderate
How does the disease interact with Lariago Injection 5 ml:
Seizures: Lariago Injection 5 ml may cause epileptic seizures in susceptible patients. Administer Lariago Injection 5 ml in patients with history of epilepsy.

How to manage the interaction:
In those who are vulnerable, Lariago Injection 5 ml may result in epileptic fits. Patients who already have epileptic fits or have a low tolerance for seizures may be at greater risk.
CHLOROQUINE-64.5MGOther diseases of blood and blood-forming organs
Moderate
How does the disease interact with Lariago Injection 5 ml:
Bone marrow suppression: With the use of Lariago Injection 5 ml adverse effects such as neutropenia, agranulocytosis, aplastic anemia, and thrombocytopenia. In patients with preexisting bone marrow suppression use cautiously and monitor for complete blood count. Discontinue the Lariago Injection 5 ml if any serious blood disorder is suspected.

How to manage the interaction:
It is important to inform your doctor if you have prior conditions like bone marrow suppression, a complete blood picture is advised to be taken if you are on a long term therapy with Lariago Injection 5 ml. If you suspect any blood disorders, please inform it to your doctor immediately.
CHLOROQUINE-64.5MGOther hearing loss
Moderate
How does the disease interact with Lariago Injection 5 ml:
Ototoxicity: Rarely, Lariago Injection 5 ml was been associated with ototoxicity.The use of Lariago Injection 5 ml has been associated rarely with ototoxicity. With long-term, high-dose Lariago Injection 5 ml therapy which is irreversible nerve-type deafness may occur. In some patients with preexisting auditory damage, tinnitus, decrease in hearing may occur. Use with caution and discontinue therapy if new auditory defects occur or if hearing loss becomes worse.

How to manage the interaction:
If you any existing hearing damage, do not forget to inform it your doctor, so that a close monitoring can be done during the treatment with Lariago Injection 5 ml.
CHLOROQUINE-64.5MGPsoriasis
Moderate
How does the disease interact with Lariago Injection 5 ml:
In psoriasis patients, the Lariago Injection 5 ml use may exacerbate severe attack of psoriasis. Do not use Lariago Injection 5 ml unless the potential benefits vs risks outweighs.

How to manage the interaction:
It is important to tell your doctor if you have any existing skin conditions like psoriasis. Your doctor may prescribe the medication, if the benefits are more than the risks.
CHLOROQUINE-64.5MGMyasthenia gravis and other myoneural disorders
Moderate
How does the disease interact with Lariago Injection 5 ml:
myasthenia gravis Use of Lariago Injection 5 ml may exacerbate new onset of symptoms in patients with previously diagnosed myasthenia gravis. Use cautiously.

How to manage the interaction:
If you are suffering from myasthenia gravis, do not forget to tell it to your doctor. If you are taking Lariago Injection 5 ml and experiencing symptoms like muscle weakness or weakness of the arms and legs, drooping of upper eyelid, difficulty speaking, difficulty swallowing, double vision, tiredness, or shortness of breath please inform your doctor.

Drug-Drug Interactions Checker List

  • CIMETIDINE
  • AMPICILLIN
  • CYCLOSPORIN
  • KAOLIN

Special Advise

Let your doctor/laboratory staff know that you are taking Lariago Injection 5 ml if you are undergoing any medical tests.

Disease/Condition Glossary

Malaria: It is a life-threatening disease caused by parasites that enter the body through a mosquito's bite. This is a common disease in Africa, South America, and Southern Asia. This disease usually occurs when an Anopheles mosquito (infected with the parasite 'Plasmodium') bites a healthy individual and transfers the parasite into the bloodstream. Parasites that cause malaria include Plasmodium vivax, P. ovale, P. malaria, and P. falciparum. Malaria symptoms usually start ten days to 4 weeks after the infection. They include chills, high fever, profuse sweating, headache, nausea, vomiting, abdominal pain, diarrhoea, anaemia, muscle pain, convulsions, coma, and bloody stools.

Extraintestinal Amebiasis: It is a parasitic infection caused by Entamoeba histolytica that spreads to various organs, most commonly the liver. When the parasite infects the liver, it leads to an amoebic liver abscess (collection of pus in the liver). An amoebic liver abscess can further cause fever and right upper quadrant abdominal pain. Apart from the liver, other body areas that can be affected by extraintestinal amebiasis include pleuropulmonary (pleura and the lungs), cardiac (heart), cerebral (brain), renal (kidneys), genitourinary (genital and urinary tracts), and cutaneous (related to skin) sites.

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