Lexa-H Tablet 10's

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Reviewed By Sunny S , MBBS

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Prescription drug

Whats That

About Lexa-H Tablet

Lexa-H Tablet is a combination medication containing 'sedative-hypnotics' used in the treatment of insomnia. Insomnia is a disorder of sleep that causes difficulty in falling asleep or staying asleep. It may be acute (short-term) or chronic (long-term) in nature due to various complications like stress, anxiety, and breathing problems.

Lexa-H Tablet contains Zolpidem and Melatonin, primarily used to treat insomnia. Zolpidem works by increasing the activity of GABA, which is a chemical messenger in the brain, acting as a natural nerve-calming agent, thereby inducing sleep. Melatonin is a natural hormone that helps to maintain the normal sleep cycle (waking up and falling asleep). Thus, Lexa-H Tablet relaxes muscles, reduces anxiety, and helps to fall asleep.

Take Lexa-H Tablet as prescribed by your doctor. You are advised to take Lexa-H Tablet for as long as your doctor has prescribed it for you, depending upon your medical condition. Preferably take Lexa-H Tablet empty stomach and just before bedtime. In some cases, you may experience nausea, headache, diarrhoea, drowsiness, and dizziness. Most of these side effects of Lexa-H Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

If you are pregnant, planning to become pregnant, or breastfeeding, please inform your doctor before starting Lexa-H Tablet . Do not stop taking Lexa-H Tablet even if you feel better, as it may lead to unpleasant side effects. Lexa-H Tablet is known to cause drowsiness, so do not drive or operate machinery. Avoid consumption of alcohol as it may reduce the effectiveness of Lexa-H Tablet . Lexa-H Tablet should not be used for daily naps.

Uses of Lexa-H Tablet

Insomnia (sleeplessness).

Directions for Use

Swallow Lexa-H Tablet as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Lexa-H Tablet is a sleeping pill used to treat insomnia (difficulty in falling or staying asleep). Zolpidem increases the activity of GABA (a chemical messenger in the brain that acts as a natural nerve-calming agent) that is involved in inducing sleep. Melatonin is a natural hormone that helps to maintain the normal sleep cycle (waking up and falling asleep). Thus, Lexa-H Tablet relaxes muscles, reduces anxiety, and helps to fall asleep. Appropriate lifestyle changes are recommended along with Lexa-H Tablet to improve the quality of sleep.

Storage

Keep Lexa-H Tablet out of the sight and reach of children.

Side effects of Lexa-H Tablet

Headache

Dealing with Medication-Induced Headache:

Hydrate your body: Drink enough water to prevent dehydration and headaches.
Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
Take rest: lie down in a quiet, dark environment.
Cold or warm compresses can help reduce tension.
Stay Upright: Maintain good posture to keep symptoms from getting worse.
To treat headaches naturally, try acupuncture or massage therapy.
Over-the-counter pain relievers include acetaminophen and ibuprofen.
Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
Frequent Headaches: If you get reoccurring headaches, consult your doctor.
Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Drowsiness

Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.

Dizziness

Here are the 7 steps to manage Dizziness caused by medication:

Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
When standing up, do so slowly and carefully to avoid sudden dizziness.
Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

Uncoordinated Muscle Movements

Uncoordinated muscle movements need immediate medical attention.
Observe your movements and try to understand and control the particular movement.
Regularly do strengthening exercises to improve blood flow throughout the body and avoid involuntary movements.
Implement massage techniques to enhance blood flow to organs.
Take a balanced diet and quit smoking.
Practice yoga and meditation to improve thought processes and reduce uncontrolled and involuntary movements.

Inability To Focus

Seeing Things That Are Not There

Hallucination is a major psychotic disorder that needs immediate medical attention.
Acknowledge your experience and put effort to control hallucinations. You can share what is being seen with a therapist to know whether they are real or imaginary.
Avoid smoking and alcohol intake as it can worsen the condition and increase your imagination.
Practice meditation and yoga to avoid anxiety, which can be one of the leading causes of hallucinations.
Talk to your dietician and consume food that can improve your mental health.

Loose And Watery Stools

Here are the precise steps to cope with diarrhoea caused by medication usage:

Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Drug Warnings

Do not take Lexa-H Tablet if you are allergic to Lexa-H Tablet or any of its ingredients. If you notice that the tablets are not working as well as they did in the beginning of the treatment, please consult a doctor as you might have developed tolerance to Lexa-H Tablet , and dose adjustment may be required. Lexa-H Tablet contains Zolpidem, a category C pregnancy drug, and is not recommended for use during pregnancy as it may cause adverse effects in the baby after birth. If you are a breastfeeding mother, it is advised to consult a doctor before using Lexa-H Tablet . If you have kidney, liver, or breathing problems, severe muscle weakness, sleep apnoea (a severe condition in which breathing stops and starts repeatedly in sleep), and if you have a history of depression or mental illness, please inform your doctor before taking Lexa-H Tablet . Maintain a time gap of a minimum of 8 hours between taking Lexa-H Tablet and driving to reduce the risk of increased adverse effects.

Drug-Drug Interactions

ZolpidemSodium oxybate

Critical

ZolpidemHydrocodone

Severe

Drug-Drug Interactions

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ZolpidemSodium oxybate

Critical

How does the drug interact with Lexa-H Tablet:
Using sodium oxybate together with Lexa-H Tablet can significantly increase the risk of severity of low blood pressure, breathing difficulties, fainting and unconsciousness.

How to manage the interaction:
Taking Sodium oxybate with Lexa-H Tablet is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate consult a doctor immediately. You should refrain from operating any dangerous machinery or driving a car. Do not stop using any medications without talking to a doctor.

ZolpidemHydrocodone

Severe

How does the drug interact with Lexa-H Tablet:
Using Lexa-H Tablet together with Hydrocodone can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Hydrocodone and Lexa-H Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, impairment in judgment, or reaction speed, consult a doctor. You should refrain from using dangerous machinery or driving a car. Do not discontinue any medications without consulting a doctor.

ZolpidemDezocine

Severe

How does the drug interact with Lexa-H Tablet:
Using Lexa-H Tablet together with Dezocine can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Dezocine and Lexa-H Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, impairment in judgment, or reaction speed, consult a doctor. You should refrain from using dangerous machinery or driving a car. Do not discontinue any medications without consulting a doctor.

ZolpidemEsketamine

Severe

How does the drug interact with Lexa-H Tablet:
Taking Lexa-H Tablet with Esketamine increases the effects of Lexa-H Tablet. This can increase the risk or severity of side effects.

How to manage the interaction:
Although taking Esketamine and Lexa-H Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, impairment in judgment, or reaction speed, consult a doctor. You should wait until the following day to operate any dangerous machinery or drive a car. Do not discontinue any medications without consulting a doctor.

ZolpidemCodeine

Severe

How does the drug interact with Lexa-H Tablet:
Using Lexa-H Tablet together with Codeine can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking codeine and Lexa-H Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, impairment in judgment, or reaction speed, consult a doctor. Do not discontinue any medications without consulting a doctor.

ZolpidemSufentanil

Severe

How does the drug interact with Lexa-H Tablet:
Using Lexa-H Tablet together with Sufentanil can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Sufentanil and Lexa-H Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, impairment in judgment, or reaction speed, consult a doctor. You should refrain from using dangerous machinery or driving a car. Do not discontinue any medications without consulting a doctor.

ZolpidemPindolol

Severe

How does the drug interact with Lexa-H Tablet:
Taking Lexa-H Tablet with Pindolol may increase the risk of low blood pressure.

How to manage the interaction:
Although taking Pindolol and Lexa-H Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.

ZolpidemMorphine

Severe

How does the drug interact with Lexa-H Tablet:
Using Lexa-H Tablet together with Morphine can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Morphine and Lexa-H Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, impairment in judgment, or reaction speed, consult a doctor. You should refrain from using dangerous machinery or driving a car. Do not discontinue any medications without consulting a doctor.

ZolpidemOxycodone

Severe

How does the drug interact with Lexa-H Tablet:
Using Lexa-H Tablet together with Oxycodone can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Oxycodone and Lexa-H Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, impairment in judgment, or reaction speed, consult a doctor. You should refrain from using dangerous machinery or driving a car. Do not discontinue any medications without consulting a doctor.

ZolpidemBuprenorphine

Severe

How does the drug interact with Lexa-H Tablet:
Taking Lexa-H Tablet with Buprenorphine can cause central nervous system depression, leading to breathing difficulty and unconsciousness.

How to manage the interaction:
Although taking Buprenorphine and Lexa-H Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, and impairment in judgment, or reaction speed, consult a doctor. You should avoid driving or operating dangerous machinery. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

MELATONIN+ZOLPIDEMCaffeine containing foods/drinks

Moderate

Drug-Food Interactions

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MELATONIN+ZOLPIDEMCaffeine containing foods/drinks

Moderate

Common Foods to Avoid:
Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu

How to manage the interaction:
Taking caffeine with Lexa-H Tablet may increase the blood levels and effects of Lexa-H Tablet. Avoid taking excessive caffeine consumption while being treated with Lexa-H Tablet.

Diet & Lifestyle Advise

Do regular exercise during day time.
Do not take a nap during day time. Set regular timings to go to bed and wake up.
Relax at least 1 hour before bedtime by bathing with warm water, listening to music, or reading a book.
Make the bedroom dark and quiet, and ensure that your pillows and mattresses are comfortable.
Avoid watching tv, using mobiles or laptops just before bedtime.
Limit caffeine intake, including tea, coffee, hot chocolate, cola, and energy drinks, as it may reduce the effectiveness of Lexa-H Tablet .
Avoid alcohol consumption as it may increase the risk of psychomotor impairment (slowdown of thought process and reduced physical movements), dependence, sleepwalking, or sleep-driving.

Side Effects of Lexa-H Tablet

Nausea
Headache
Diarrhoea
Drowsiness
Dizziness

Habit Forming

Yes

Therapeutic Class

SEDATIVE-HYPNOTIC DRUGS

Drug-Diseases Interactions

No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

How does Lexa-H Tablet work?

Lexa-H Tablet is a sleeping pill used to treat insomnia (difficulty in falling or staying asleep). Zolpidem increases the activity of GABA (a chemical messenger in the brain that acts as a natural nerve-calming agent) that is involved in inducing sleep. Melatonin is a natural hormone that helps to maintain the normal sleep cycle (waking up and falling asleep)

Is Lexa-H Tablet safe for depression patients?

No, Lexa-H Tablet is not recommended for depression patients as it may worsen the condition and increase self-harming or suicidal thoughts. Therefore, if you are suffering from depression or have a history of depression, please inform your doctor before taking Lexa-H Tablet .

What is the best time to take Lexa-H Tablet ?

You are recommended to take Lexa-H Tablet just before bedtime as it helps to sleep quickly and improves sleep quality. If you forget to take Lexa-H Tablet at night, do not take it in the day time as it may cause drowsiness, confusion and dizziness.

Can I take Lexa-H Tablet with hydrocodone (pain killer)?

No, you are not recommended to take Lexa-H Tablet with hydrocodone or other opioid pain killers such as oxycodone, naloxone, and tramadol as co-administration of these medicines with Lexa-H Tablet may increase the risk of difficulty in breathing, drowsiness, coma, and even death. However, before using Lexa-H Tablet with any other medicines, you are advised to contact your doctor so that the dose may be adjusted to use safely.

Does Lexa-H Tablet cause dependence?

Yes, Lexa-H Tablet may cause dependence (mental and physical effects caused due to compulsion of taking Lexa-H Tablet ) if used in high doses and for a prolonged time. This risk of dependency on Lexa-H Tablet increases in patients who have a history of drug or alcohol abuse.

Drug-Drug Interactions Checker List

METOPROLOL
HYDROCODONE
SERTRALINE
CIPROFLOXACIN
RIFAMPICIN
KETOCONAZOLE
ALPRAZOLAM
DIPHENHYDRAMINE
CYCLOBENZAPRINE
GABAPENTIN
CIMETIDINE
MIDAZOLAM

Special Advise

You are advised to take Lexa-H Tablet on an empty stomach as taking Lexa-H Tablet with food may reduce the effect of Lexa-H Tablet .
If you are depressed or have depression in the past, please inform your doctor before taking Lexa-H Tablet as it may increase self-harming or suicidal thoughts.
If you notice any behavioural side effects such as delusions (false belief), nightmares, irritability, restlessness, aggressiveness, or hallucinations (hear, feel or see things that are actually not present), please contact your doctor.
If you are allergic to any sugars, inform your doctor as Lexa-H Tablet contains lactose.

Disease/Condition Glossary

Insomnia: It is a disorder of sleep associated with problems in falling asleep or staying asleep. It may be acute (short-term) or chronic (long-term) in nature. Acute insomnia may last from one night to a few weeks and occurs due to stress or life changes. Chronic insomnia may last from more than 3 nights per week to more than 3 months. Insomnia is mostly caused due to depression, stress, anxiety, jet lag, shift work, uncomfortable beds, chronic illness, caffeine, nicotine, alcohol intake, or certain medicines. It may be treated using sleeping pills, behaviour therapy, sleep habits changes, and identifying and treating chronic conditions.