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Reviewed By Sunny S , MBBS
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Manufacturer/Marketer :

Seagull Pharmaceutical Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Lexa-H Tablet

Lexa-H Tablet is a combination medication containing 'sedative-hypnotics' used in the treatment of insomnia. Insomnia is a disorder of sleep that causes difficulty in falling asleep or staying asleep. It may be acute (short-term) or chronic (long-term) in nature due to various complications like stress, anxiety, and breathing problems.

Lexa-H Tablet contains Zolpidem and Melatonin, primarily used to treat insomnia. Zolpidem works by increasing the activity of GABA, which is a chemical messenger in the brain, acting as a natural nerve-calming agent, thereby inducing sleep. Melatonin is a natural hormone that helps to maintain the normal sleep cycle (waking up and falling asleep).  Thus, Lexa-H Tablet relaxes muscles, reduces anxiety, and helps to fall asleep.

Take Lexa-H Tablet as prescribed by your doctor. You are advised to take Lexa-H Tablet for as long as your doctor has prescribed it for you, depending upon your medical condition. Preferably take Lexa-H Tablet empty stomach and just before bedtime. In some cases, you may experience nausea, headache, diarrhoea, drowsiness, and dizziness. Most of these side effects of Lexa-H Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

If you are pregnant, planning to become pregnant, or breastfeeding, please inform your doctor before starting Lexa-H Tablet . Do not stop taking Lexa-H Tablet even if you feel better, as it may lead to unpleasant side effects. Lexa-H Tablet is known to cause drowsiness, so do not drive or operate machinery. Avoid consumption of alcohol as it may reduce the effectiveness of Lexa-H Tablet . Lexa-H Tablet should not be used for daily naps.

Uses of Lexa-H Tablet

Insomnia (sleeplessness).

Directions for Use

Swallow Lexa-H Tablet as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Lexa-H Tablet is a sleeping pill used to treat insomnia (difficulty in falling or staying asleep). Zolpidem increases the activity of GABA (a chemical messenger in the brain that acts as a natural nerve-calming agent) that is involved in inducing sleep. Melatonin is a natural hormone that helps to maintain the normal sleep cycle (waking up and falling asleep). Thus, Lexa-H Tablet relaxes muscles, reduces anxiety, and helps to fall asleep. Appropriate lifestyle changes are recommended along with Lexa-H Tablet to improve the quality of sleep.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Lexa-H Tablet if you are allergic to Lexa-H Tablet or any of its ingredients. If you notice that the tablets are not working as well as they did in the beginning of the treatment, please consult a doctor as you might have developed tolerance to Lexa-H Tablet , and dose adjustment may be required. Lexa-H Tablet contains Zolpidem, a category C pregnancy drug, and is not recommended for use during pregnancy as it may cause adverse effects in the baby after birth. If you are a breastfeeding mother, it is advised to consult a doctor before using Lexa-H Tablet . If you have kidney, liver, or breathing problems, severe muscle weakness, sleep apnoea (a severe condition in which breathing stops and starts repeatedly in sleep), and if you have a history of depression or mental illness, please inform your doctor before taking Lexa-H Tablet . Maintain a time gap of a minimum of 8 hours between taking Lexa-H Tablet and driving to reduce the risk of increased adverse effects.

Drug-Drug Interactions

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ZolpidemSodium oxybate
Critical
ZolpidemCiprofloxacin
Severe

Drug-Drug Interactions

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ZolpidemSodium oxybate
Critical
How does the drug interact with Lexa-H Tablet:
Using sodium oxybate together with Lexa-H Tablet can significantly increase the risk of severity of low blood pressure, breathing difficulties, fainting and unconsciousness.

How to manage the interaction:
Taking Sodium oxybate with Lexa-H Tablet is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate consult a doctor immediately. You should refrain from operating any dangerous machinery or driving a car. Do not stop using any medications without talking to a doctor.
ZolpidemCiprofloxacin
Severe
How does the drug interact with Lexa-H Tablet:
Coadministration of Lexa-H Tablet with ciprofloxacin can increase the blood levels and effects of Lexa-H Tablet. This can increase the risk or severity of side effects.

How to manage the interaction:
Although taking ciprofloxacin and Lexa-H Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience drowsiness, dizziness, or sleep disturbances, consult a doctor. Do not discontinue any medications without consulting a doctor.
ZolpidemFentanyl
Severe
How does the drug interact with Lexa-H Tablet:
Using Lexa-H Tablet together with Fentanyl can cause central nervous system depression.

How to manage the interaction:
Although taking Fentanyl and Lexa-H Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor if you experience dizziness, sleepiness, difficulty concentrating, and impaired judgment. Do not discontinue any medications without consulting a doctor.
ZolpidemOxycodone
Severe
How does the drug interact with Lexa-H Tablet:
Using Lexa-H Tablet together with Oxycodone can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Oxycodone and Lexa-H Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, impairment in judgment, or reaction speed, consult a doctor. You should refrain from using dangerous machinery or driving a car. Do not discontinue any medications without consulting a doctor.
ZolpidemPethidine
Severe
How does the drug interact with Lexa-H Tablet:
Taking Lexa-H Tablet with Pethidine may increase the risk of central nervous system depression, which can lead to breathing difficulty and unconsciousness.

How to manage the interaction:
Although taking Pethidine and Lexa-H Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, impairment in judgment, or reaction speed, consult a doctor. Do not discontinue any medications without consulting a doctor.
ZolpidemDezocine
Severe
How does the drug interact with Lexa-H Tablet:
Using Lexa-H Tablet together with Dezocine can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Dezocine and Lexa-H Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, impairment in judgment, or reaction speed, consult a doctor. You should refrain from using dangerous machinery or driving a car. Do not discontinue any medications without consulting a doctor.
ZolpidemPentazocine
Severe
How does the drug interact with Lexa-H Tablet:
Using Lexa-H Tablet together with Pentazocine can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Pentazocine and Lexa-H Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, impairment in judgment, or reaction speed, consult a doctor. You should refrain from using dangerous machinery or driving a car. Do not discontinue any medications without consulting a doctor.
ZolpidemKetamine
Severe
How does the drug interact with Lexa-H Tablet:
Taking Lexa-H Tablet with Ketamine increases the effects of Lexa-H Tablet. This can increase the risk or severity of side effects.

How to manage the interaction:
Although taking Ketamine and Lexa-H Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, impairment in judgment, or reaction speed, consult a doctor. You should wait until the following day to operate any dangerous machinery or drive a car. Do not discontinue any medications without consulting a doctor.
ZolpidemButorphanol
Severe
How does the drug interact with Lexa-H Tablet:
Using Lexa-H Tablet together with Butorphanol can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Butorphanol and Lexa-H Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, and impairment in judgment, or reaction speed, avoid driving or operating hazardous machinery consult a doctor. Do not stop using any medications without a doctor's advice.
ZolpidemHydrocodone
Severe
How does the drug interact with Lexa-H Tablet:
Using Lexa-H Tablet together with Hydrocodone can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Hydrocodone and Lexa-H Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, impairment in judgment, or reaction speed, consult a doctor. You should refrain from using dangerous machinery or driving a car. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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MELATONIN+ZOLPIDEMCaffeine containing foods/drinks
Moderate

Drug-Food Interactions

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MELATONIN+ZOLPIDEMCaffeine containing foods/drinks
Moderate
Common Foods to Avoid:
Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu

How to manage the interaction:
Taking caffeine with Lexa-H Tablet may increase the blood levels and effects of Lexa-H Tablet. Avoid taking excessive caffeine consumption while being treated with Lexa-H Tablet.

Diet & Lifestyle Advise

  • Do regular exercise during day time.
  • Do not take a nap during day time. Set regular timings to go to bed and wake up.
  • Relax at least 1 hour before bedtime by bathing with warm water, listening to music, or reading a book.
  • Make the bedroom dark and quiet, and ensure that your pillows and mattresses are comfortable.
  • Avoid watching tv, using mobiles or laptops just before bedtime.
  • Limit caffeine intake, including tea, coffee, hot chocolate, cola, and energy drinks, as it may reduce the effectiveness of Lexa-H Tablet .
  • Avoid alcohol consumption as it may increase the risk of psychomotor impairment (slowdown of thought process and reduced physical movements), dependence, sleepwalking, or sleep-driving.

Habit Forming

Yes

Therapeutic Class

SEDATIVE-HYPNOTIC DRUGS

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Lexa-H Tablet is a sleeping pill used to treat insomnia (difficulty in falling or staying asleep). Zolpidem increases the activity of GABA (a chemical messenger in the brain that acts as a natural nerve-calming agent) that is involved in inducing sleep. Melatonin is a natural hormone that helps to maintain the normal sleep cycle (waking up and falling asleep)

No, Lexa-H Tablet is not recommended for depression patients as it may worsen the condition and increase self-harming or suicidal thoughts. Therefore, if you are suffering from depression or have a history of depression, please inform your doctor before taking Lexa-H Tablet .

You are recommended to take Lexa-H Tablet just before bedtime as it helps to sleep quickly and improves sleep quality. If you forget to take Lexa-H Tablet at night, do not take it in the day time as it may cause drowsiness, confusion and dizziness.

No, you are not recommended to take Lexa-H Tablet with hydrocodone or other opioid pain killers such as oxycodone, naloxone, and tramadol as co-administration of these medicines with Lexa-H Tablet may increase the risk of difficulty in breathing, drowsiness, coma, and even death. However, before using Lexa-H Tablet with any other medicines, you are advised to contact your doctor so that the dose may be adjusted to use safely.

Yes, Lexa-H Tablet may cause dependence (mental and physical effects caused due to compulsion of taking Lexa-H Tablet ) if used in high doses and for a prolonged time. This risk of dependency on Lexa-H Tablet increases in patients who have a history of drug or alcohol abuse.

Drug-Drug Interactions Checker List

  • METOPROLOL
  • HYDROCODONE
  • SERTRALINE
  • CIPROFLOXACIN
  • RIFAMPICIN
  • KETOCONAZOLE
  • ALPRAZOLAM
  • DIPHENHYDRAMINE
  • CYCLOBENZAPRINE
  • GABAPENTIN
  • CIMETIDINE
  • MIDAZOLAM

Special Advise

  • You are advised to take Lexa-H Tablet on an empty stomach as taking Lexa-H Tablet with food may reduce the effect of Lexa-H Tablet .
  • If you are depressed or have depression in the past, please inform your doctor before taking Lexa-H Tablet as it may increase self-harming or suicidal thoughts.
  • If you notice any behavioural side effects such as delusions (false belief), nightmares, irritability, restlessness, aggressiveness, or hallucinations (hear, feel or see things that are actually not present), please contact your doctor.
  • If you are allergic to any sugars, inform your doctor as Lexa-H Tablet contains lactose.

Disease/Condition Glossary

Insomnia: It is a disorder of sleep associated with problems in falling asleep or staying asleep. It may be acute (short-term) or chronic (long-term) in nature. Acute insomnia may last from one night to a few weeks and occurs due to stress or life changes. Chronic insomnia may last from more than 3 nights per week to more than 3 months. Insomnia is mostly caused due to depression, stress, anxiety, jet lag, shift work, uncomfortable beds, chronic illness, caffeine, nicotine, alcohol intake, or certain medicines. It may be treated using sleeping pills, behaviour therapy, sleep habits changes, and identifying and treating chronic conditions.

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