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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sunny S , MBBS

About Liofen Liquid 100 ml

Liofen Liquid 100 ml belongs to the group of medicines called 'muscle relaxants' used to reduce and relieve the muscle spasms (excessive tension in the muscles) occurring in various illnesses. Muscle spasm is the sudden involuntary contractions of the muscle, which can be painful and uncomfortable. When the nerve impulses that control the muscle movements are damaged or interrupted, it could lead to muscle spasms.

Liofen Liquid 100 ml works by inhibiting the reflexes at the spinal level and helps in relieving pain and improves muscle movements. Liofen Liquid 100 ml works on the spinal cord and brain, thereby helps in maintaining muscle strength and relieves muscle spasms or stiffness. Thus Liofen Liquid 100 ml reduces muscle spasm in the conditions of multiple sclerosis (a disorder which affects the brain and spinal cord), cerebrovascular accidents (damage to the brain due to lack of blood supply), cerebral palsy (a disorder of movement, posture and muscle tone), spinal cord diseases and other nervous system disorders.

Take Liofen Liquid 100 ml with food. You are advised to take Liofen Liquid 100 ml for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as sleepiness, drowsiness, nausea, headache, weakness, and dry mouth. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are suggested to talk to your doctor if you experience these side-effects persistently.

Do not discontinue Liofen Liquid 100 ml suddenly as it could lead to unpleasant side-effects such as rigidity, increased heart rate, changes in mood, fever, mental disorders, confusion, hallucinations, and fits (seizures). Consult your doctor before taking Liofen Liquid 100 ml if you are pregnant or breastfeeding. Liofen Liquid 100 ml is not recommended for children below 4 years of age and those who weigh below 33kgs. Inform your doctor about all the current medicines you are taking and about your health condition to rule out any unpleasant side-effects. Please speak to your doctor immediately if you experience mood swings, depression, or if you have any suicidal thoughts.

rxMedicinePrescription drug

Whats That

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Non returnable*
COD available

Online payment accepted

Composition

BACLOFEN-5MG

Consume Type

ORAL

Return Policy

3 Days Returnable

Expires on or after

Apr-24

for this medicine

Uses of Liofen Liquid 100 ml

Muscle spasm

Medicinal Benefits

Liofen Liquid 100 ml belongs to the group of medicines called muscle relaxants used to reduce and relieve the muscle spasms (excessive tension in the muscles) occurring in various illnesses such as multiple sclerosis (a disorder which affects the brain and spinal cord), cerebrovascular accidents (damage to the brain due to lack of blood supply), cerebral palsy (a disorder of movement, posture and muscle tone), spinal cord diseases and other nervous system disorders. Liofen Liquid 100 ml works by inhibiting the reflexes at the spinal level and helps in relieving pain and improves muscle movements. Liofen Liquid 100 ml is particularly effective for relieving involuntary muscle spasms in the ankle, hip, and knee. Liofen Liquid 100 ml also helps in restoring muscle function; however, Liofen Liquid 100 ml is not effective for muscle spasms caused by stroke, Parkinson’s disease, or rheumatoid arthritis. Liofen Liquid 100 ml works on the centres of the spinal cord and brain, thereby helps in maintaining muscle strength and relieving muscle spasms or stiffness. Liofen Liquid 100 ml is used off-label to treat hiccups or Tourette’s syndrome (a nervous problem which causes people to make uncontrollable sudden movements or sounds).

Side Effects of Liofen Liquid 100 ml

  • Sleepiness
  • Drowsiness
  • Nausea
  • Headache
  • Weakness
  • Dry mouth

Directions for Use

Tablet/Capsule: Swallow it as a whole with a glass of water or milk; do not crush, chew, or break the tablet/capsule. Liquid: Shake the bottle well and take the prescribed dose/quantity by mouth using the measuring cup/dosing syringe.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Liofen Liquid 100 ml if you are allergic to any of its contents or if you ever had a stomach ulcer. Talk to your doctor before taking Liofen Liquid 100 ml if you have kidney or liver problems, mental disorders, breathing difficulty or lung disease, diabetes, difficulty in urination, high blood pressure, Parkinson’s disease, or if you ever had a stroke. Consult your doctor before taking Liofen Liquid 100 ml if you are pregnant or breastfeeding. Liofen Liquid 100 ml is not recommended for children below four years of age and those who weigh below 33 kg.

Therapeutic Class

SKELETAL MUSCLE RELAXANTS

Drug-Drug Interactions

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BaclofenHydrocodone
Severe
BaclofenSodium oxybate
Severe

Drug-Drug Interactions

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BaclofenHydrocodone
Severe
How does the drug interact with Liofen Liquid 100 ml:
Co-administration of Liofen Liquid 100 ml with Hydrocodone may increase sedation and respiratory distress (fluid collects in the air sacs of the lungs)

How to manage the interaction:
Although there is an interaction, Liofen Liquid 100 ml can be used with Hydrocodone if prescribed by the doctor. Co-administration of these medications may cause dizziness, drowsiness, difficulty in concentrating, and impaired judgment. Do not stop any medication without doctor's consultation.
BaclofenSodium oxybate
Severe
How does the drug interact with Liofen Liquid 100 ml:
Co-administration of Sodium oxybate with Liofen Liquid 100 ml may increase side effects.

How to manage the interaction:
Although there is an interaction, Liofen Liquid 100 ml can be used with Sodium oxybate if prescribed by the doctor. Consult the prescriber if you experience drowsiness, dizziness, lightheadedness, confusion, depression, low blood pressure, slow or shallow breathing, and impairment in thinking, judgment, and motor coordination.
BaclofenPentazocine
Severe
How does the drug interact with Liofen Liquid 100 ml:
Co-administration of Liofen Liquid 100 ml can enhance the sedative effects of Pentazocine on the central nervous system which can lead to side effects such as respiratory distress (a condition in which fluid builds up in the lungs).

How to manage the interaction:
Although there is a possible interaction between Pentazocine and Liofen Liquid 100 ml, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
BaclofenBuprenorphine
Severe
How does the drug interact with Liofen Liquid 100 ml:
Co-administration of Buprenorphine with Liofen Liquid 100 ml can increase the risk of side effects.

How to manage the interaction:
Co-administration of Buprenorphine alongside Liofen Liquid 100 ml can result in an interaction. However, it can be taken if a doctor has advised it. If you experience shortness of breath, chest discomfort, dizziness, or palpitations consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
BaclofenButorphanol
Severe
How does the drug interact with Liofen Liquid 100 ml:
Co-administration of Liofen Liquid 100 ml with Butorphanol can increase the risk of developing side effects.

How to manage the interaction:
Although there is a possible interaction between Liofen Liquid 100 ml and Butorphanol, you can take these medicines together if prescribed by your doctor. If you notice any symptoms like dizziness, shortness of breath, palpitations, or chest discomfort, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
BaclofenTapentadol
Severe
How does the drug interact with Liofen Liquid 100 ml:
Co-administration of Tapentadol together with Liofen Liquid 100 ml can increase the risk or severity of side effects like decreased breathing rate, irregular heart rhythms, or problems with movement and memory.

How to manage the interaction:
Taking Liofen Liquid 100 ml with Tapentadol can result in an interaction, it can be taken if a doctor has advised it. Contact a doctor immediately if you experience signs such as drowsiness, lightheadedness, palpitations, confusion, severe weakness, or difficulty breathing. Do not discontinue any medications without consulting a doctor.
BaclofenHydromorphone
Severe
How does the drug interact with Liofen Liquid 100 ml:
Co-administration of Liofen Liquid 100 ml with Hydromorphone may increase the central nervous system and can lead to serious side effects including respiratory distress (a condition in which fluid builds up in the lungs).

How to manage the interaction:
Although there is an interaction, Liofen Liquid 100 ml can be used with Hydromorphone if prescribed by the doctor. Inform the prescriber if you are taking these two medicines, the doctor may prescribe alternate medicines or a dose adjustment, or more frequent monitoring to safely use both medications. Do not discontinue any medications without consulting a doctor.
BaclofenMethadone
Severe
How does the drug interact with Liofen Liquid 100 ml:
Co-administration of Liofen Liquid 100 ml with Methadone may cause serious side effects such as central nervous system depression can lead to serious side effects including respiratory distress (a condition in which fluid builds up in the lungs).

How to manage the interaction:
Although there is an interaction, Liofen Liquid 100 ml can be used with Methadone if prescribed by the doctor. Inform the prescriber if you are taking these two medicines, the doctor may prescribe alternate medicines a dose adjustment, or more frequent monitoring to safely use both medications. Do not discontinue any medications without consulting a doctor.
BaclofenDezocine
Severe
How does the drug interact with Liofen Liquid 100 ml:
Co-administration of Liofen Liquid 100 ml with Dezocine can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction, Liofen Liquid 100 ml can be used with Dezocine if prescribed by the doctor. These may cause dizziness, drowsiness, palpitations, or chest discomfort. Do not stop taking the medications without a doctor's advice.
BaclofenRemifentanil
Severe
How does the drug interact with Liofen Liquid 100 ml:
Co-administration of Liofen Liquid 100 ml can enhance the sedative effects of Remifentanil on the central nervous system which can lead to serious side effects such as respiratory distress (a condition in which fluid builds up in the lungs).

How to manage the interaction:
Co-administration of Liofen Liquid 100 ml with Remifentanil can possibly result in an interaction, but it can be taken if a doctor has advised it. They can recommend other options that won't cause any problems. If you notice any symptoms like feeling tired, dizzy, or having trouble focusing, make sure to contact a doctor right away. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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BACLOFEN-5MGOther disorders of kidney and ureter, not elsewhere classified
Severe
BACLOFEN-5MGDisorders of autonomic nervous system
Moderate

Drug-Diseases Interactions

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BACLOFEN-5MGOther disorders of kidney and ureter, not elsewhere classified
Severe
How does the disease interact with Liofen Liquid 100 ml:
The kidney is the main organ used to remove Liofen Liquid 100 ml. Liofen Liquid 100 ml side effects may be more likely to occur in patients with poor renal function due to decreased medication clearance. In these patients, Liofen Liquid 100 ml therapy should be used with caution. It could be required to modify the dosage.

How to manage the interaction:
Therapy with Liofen Liquid 100 ml should be administered cautiously in such patients. Dosage adjustments may be necessary.
BACLOFEN-5MGDisorders of autonomic nervous system
Moderate
How does the disease interact with Liofen Liquid 100 ml:
Patients with a history of autonomic dysreflexia should be treated with intrathecal Liofen Liquid 100 ml with caution because the drug's rapid withdrawal or the presence of nociceptive stimuli can cause an episode of dysreflexia.

How to manage the interaction:
Liofen Liquid 100 ml should be administered cautiously in patients with autonomic dysreflexia.
BACLOFEN-5MGMental disorder, not otherwise specified
Moderate
How does the disease interact with Liofen Liquid 100 ml:
Both during therapy and after an abrupt withdrawal from the drug, Liofen Liquid 100 ml may cause or aggravate psychotic symptoms. Patients having a history of psychiatric illnesses should be treated with Liofen Liquid 100 ml with caution.

How to manage the interaction:
Liofen Liquid 100 ml may precipitate or exacerbate psychotic symptoms, both during therapy and following abrupt withdrawal of the drug. Therapy with Liofen Liquid 100 ml should be administered cautiously in patients with a history of psychiatric disorders.
BACLOFEN-5MGConvulsions, not elsewhere classified
Moderate
How does the disease interact with Liofen Liquid 100 ml:
Liofen Liquid 100 ml treatment for epilepsy has occasionally been associated with electroencephalographic (EEG) abnormalities and a decline in seizure control. Patients having a history of seizures should receive Liofen Liquid 100 ml therapy with caution. Throughout treatment, clinical conditions and EEG should be monitored often.

How to manage the interaction:
Liofen Liquid 100 ml may occasionally cause decrease in seizure control. Therapy with Liofen Liquid 100 ml should be administered cautiously in patients with a history of seizures.

Drug-Drug Interactions Checker List

  • HYDROCODONE
  • ACETAMINOPHEN
  • IBUPROFEN
  • MORPHINE
  • FENTANYL
  • TRAMADOL
  • NALOXONE
  • TIZANIDINE
  • LITHIUM
  • AMITRIPTYLINE
  • DILTIAZEM
  • LEVODOPA
  • PROMETHAZINE
  • CARBAMAZEPINE

Diet & Lifestyle Advise

  • Exercising regularly helps in muscle stretching so that they are less likely to spasm, tear, and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.
  • Massages can also be helpful.
  • Avoid extremely cold and hot temperatures.
  • Avoid wearing tight-fitting clothes, instead, wear loose garments.
  • Rest well, get plenty of sleep.
  • To avoid developing pressure sores, change your position at least every two hours.
  • Hot or cold therapy can be helpful in treating muscle spasms. Apply an ice-pack or hot-pack on the muscle for 15-20minutes.
  • Stay hydrated, drink plenty of water.

Habit Forming

No

Special Advise

  • Your doctor may advise you to undergo regular blood tests to monitor liver function.
  • Inform your doctor that you are taking Liofen Liquid 100 ml if you are due to undergo any surgery which requires a general anaesthetic.
  • Please talk to your doctor immediately if you experience mood swings, depression, or if you have any suicidal thoughts.

Author Details

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Disease/Condition Glossary

Muscle spasm: It is the sudden involuntary contractions of the muscle, which can be painful and uncomfortable. When the nerve impulses that control the muscle movements are damaged or interrupted, it could lead to muscle spasms. Symptoms include muscle tightness, joint stiffness, unusual posture, difficulty in moving, pain in affected muscles, and joints. Fatigue (weakness), stress, extreme heat or cold, infection, and tight clothing can trigger muscle spasms. Muscle relaxants and exercise can treat muscle spasms. Muscle relaxants sedate the muscle and help in inhibiting painful contractions. Exercise helps in muscle stretching so that they are less likely to spasm, tear, and sprain.

Liofen Liquid 100 ml Substitute

Substitutes safety advice
  • Liofen 5 Tablet 10's

    5.99per tablet
  • Bacfen 5 Tablet 10's

    5.99per tablet
  • BACLOTABLETS 5MG TABLETS 15'S

    by AYUR

    6.36per tablet
  • Bacwell-5 Tablet 10's

    5.72per tablet
  • Bolofen-5 Tablet 10's

    6.35per tablet
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