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  3. Macdaxa 150 mg Capsule 10's

Macdaxa 150 mg Capsule 10's, Pack of 10 CAPSULES
Macdaxa 150 mg Capsule 10's, Pack of 10 CAPSULES
Written By ,
Reviewed By Hari Kumar , MBBS
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Whats That

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Composition :

DABIGATRAN ETEXILATE-150MG

Manufacturer/Marketer :

Macleods Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Macdaxa 150 mg Capsule

Macdaxa 150 mg Capsule belongs to a class of drugs known as anticoagulants or blood thinners used to prevent and treat the risk of stroke, heart attack in patients with atrial fibrillation (irregular heart rhythm) by reducing blood clot formation. Besides this, it is also used to prevent deep vein thrombosis (blood clots in leg veins), pulmonary embolism (blood clots in the lung), and to reduce the risk of clots in people who have undergone knee or hip replacement surgeries. 

Macdaxa 150 mg Capsule contains Dabigatran etexilate that works by inhibiting the production of clotting factor Xa, also called thrombin. This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clots formation. It makes the blood flow easily through the veins making it less likely to form a serious blood clot. Thus, Macdaxa 150 mg Capsule helps prevent blood clots thereby reducing the risk of heart attack/stroke.

Take Macdaxa 150 mg Capsule as prescribed by your doctor. You are advised to take Macdaxa 150 mg Capsule for as long as your doctor has prescribed it for you depending on your medical conditions. You may experience bleeding, anaemia (low number of red blood cells), nausea, stomach pain, and vomiting. Most of these side effects of Macdaxa 150 mg Capsule do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

If you are known to be allergic to Macdaxa 150 mg Capsule or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Macdaxa 150 mg Capsule . If you have a stomach ulcer, kidney or liver problems, high blood pressure, or bleeding problems, inform your doctor before taking Macdaxa 150 mg Capsule . Try not to stop taking this medicine on your own. Discontinuing Macdaxa 150 mg Capsule may worsen your condition and increase the risk of heart attack, and stroke.

Uses of Macdaxa 150 mg Capsule

Prevention of blood clot formation, deep vein thrombosis, pulmonary embolism.

Directions for Use

Take Macdaxa 150 mg Capsule exactly as your doctor has prescribed it. Swallow it as a whole with water; do not crush or chew it.

Medicinal Benefits

Macdaxa 150 mg Capsule belongs to a class of drugs known as anticoagulants or blood thinners. Macdaxa 150 mg Capsule is primarily used to prevent and treat the risk of stroke and heart attack by reducing blood clot formation. Besides this, it also reduces the risk of getting clots in people who have undergone knee or hip replacement surgeries. Macdaxa 150 mg Capsule works by stopping the action of clotting factor (thrombin). This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clots formation.

Storage

Store in a cool and dry place away from sunlight
Side effects of Macdaxa 150 mg Capsule
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • You can take your medicine with meals to lower the chances of getting stomach pain.
  • Avoid foods that are acidic, spicy, sugary, or greasy.
  • Eat foods that are easily digestible such as rice, toast, and bananas.
  • Eat your meals in smaller amounts throughout the day to prevent strain on your stomach and digestion.
  • Drink water or fluids to stay hydrated and prevent stomach upset.
  • Use a heating pad or massage your stomach area.
  • Engage in mild physical activities such as yoga and walking.

Drug Warnings

If you are known to be allergic to Macdaxa 150 mg Capsule or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Macdaxa 150 mg Capsule . Macdaxa 150 mg Capsule is not recommended for children less than 18 years of age as the Safety and effectiveness have not been established. If you have an artificial heart valve, stomach ulcer, kidney/liver problems, high blood pressure, or bleeding problems, inform your doctor before taking Macdaxa 150 mg Capsule . You should inform the doctor that you are taking Macdaxa 150 mg Capsule if you are due to undergo surgery. Avoid consumption of alcohol while taking Macdaxa 150 mg Capsule as it may increase the risk of stomach bleeding.

Drug-Drug Interactions

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Dabigatran etexilateMifepristone
Critical
Dabigatran etexilateDalteparin
Severe

Drug-Drug Interactions

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Dabigatran etexilateMifepristone
Critical
How does the drug interact with Macdaxa 150 mg Capsule:
When Mifepristone is taken with Macdaxa 150 mg Capsule, it may increase the risk of severe vaginal bleeding in women.

How to manage the interaction:
Taking Mifepristone with Macdaxa 150 mg Capsule is not recommended, but it can be taken if prescribed by the doctor. However, if you experience heavy, persistent vaginal bleeding, consult the door. Do not stop using any medications without talking to a doctor.
Dabigatran etexilateDalteparin
Severe
How does the drug interact with Macdaxa 150 mg Capsule:
Using dabigatran together with dalteparin may increase the risk of bleeding.

How to manage the interaction:
Although taking Dalteparin with Macdaxa 150 mg Capsule may possibly lead to an interaction, they can be taken if a doctor prescribes it. Consult a doctor if you have any symptoms including dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that resembles coffee grounds, severe headache, and weakness. Without consulting a doctor, never stop taking any medication.
Dabigatran etexilateFlurbiprofen
Severe
How does the drug interact with Macdaxa 150 mg Capsule:
Taking Flurbiprofen with Macdaxa 150 mg Capsule can increase the risk of bleeding and hemorrhage.

How to manage the interaction:
Although taking Flurbiprofen and Macdaxa 150 mg Capsule together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you experience bleeding, feeling dizzy or lightheaded, dark or sticky stools, throwing up blood, severe headache, or feeling weak contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
Dabigatran etexilateEnoxaparin
Severe
How does the drug interact with Macdaxa 150 mg Capsule:
Macdaxa 150 mg Capsule can make Enoxaparin more effective at preventing blood clotting, this can increase the risk or severity of bleeding.

How to manage the interaction:
There may be a possibility of interaction between Enoxaparin and Macdaxa 150 mg Capsule, but it can be taken if prescribed by a doctor. If you notice any of these signs, it's important to contact a doctor right away: bleeding that doesn't stop, blood in your stool, dizziness, dark or bloody stools, headache, weakness, or vomiting blood. Do not stop using any medications without talking to a doctor.
Dabigatran etexilateClopidogrel
Severe
How does the drug interact with Macdaxa 150 mg Capsule:
Taking Clopidogrel with Dabigatran may increase the risk of bleeding.

How to manage the interaction:
Although there may be an interaction between clopidogrel and Apixaban, they can be taken together if advised by your doctor. However, consult your doctor immediately if you experience any unusual bleeding, dizziness or lightheadedness, red or black, sticky stools, or headaches. Do not discontinue any medication without consulting your doctor.
Dabigatran etexilateDiclofenac
Severe
How does the drug interact with Macdaxa 150 mg Capsule:
Concomitant use of diclofenac with dabigatran may increase the risk of stomach bleeding.

How to manage the interaction:
Taking diclofenac with dabigatran together possibly results in an interaction, it can be taken if your doctor has advised it. You should consult a doctor immediately if you experience any unusual bleeding or bruising or have other signs and symptoms of bleeding such as dizziness, light headedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache and weakness. Do not stop using any medications without first talking to your doctor.
Dabigatran etexilateDeferasirox
Severe
How does the drug interact with Macdaxa 150 mg Capsule:
Combining Macdaxa 150 mg Capsule with Deferasirox can increase the risk of gastrointestinal bleeding.

How to manage the interaction:
Co-administration of Macdaxa 150 mg Capsule with Deferasirox can possibly result in an interaction, but it can be taken if your doctor has advised it. This risk is higher in older people with certain blood disorders or low platelet counts.If you have symptoms like stomach pain, bloating, dizziness, or black stools, it's important to consult a doctor. Do not stop using any medications without a doctor's advice.
Dabigatran etexilateMefenamic acid
Severe
How does the drug interact with Macdaxa 150 mg Capsule:
Coadministration of Mefenamic acid with Dabigatran can increase the risk or severity of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Mefenamic acid with Macdaxa 150 mg Capsule together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Dabigatran etexilateCilostazol
Severe
How does the drug interact with Macdaxa 150 mg Capsule:
Co-administration of dabigatron etexilate with cilostazol can increase the risk or severity of bleeding.

How to manage the interaction:
Taking dabigatron etexilate with cilostazol together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience any symptoms such as unusual bleeding or bruising, dizziness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not discontinue any medications without consulting a doctor.
Dabigatran etexilateIndometacin
Severe
How does the drug interact with Macdaxa 150 mg Capsule:
Using Indomethacin with Macdaxa 150 mg Capsule can increase the risk of bleeding.

How to manage the interaction:
Taking Indometacin with Macdaxa 150 mg Capsule together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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DABIGATRAN ETEXILATE-150MGHerbal products/medicines

Drug-Food Interactions

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DABIGATRAN ETEXILATE-150MGHerbal products/medicines
Common Foods to Avoid:
St. John’S Wort, Garlic Pill

How to manage the interaction:
Herbs and supplements may interact with Macdaxa 150 mg Capsule. Avoid St. John's Wort, herbs including garlic, ginger, bilberry, danshen, piracetam, and ginkgo biloba during Macdaxa 150 mg Capsule treatment.

Diet & Lifestyle Advise

  • Keep your cholesterol and triglyceride levels under control.
  • Eat at regular intervals, and maintain a healthy diet that includes fresh fruits, vegetables.
  • Limit alcohol intake since it raises blood pressure and increases the risk of heart diseases.
  • Keep a check on your weight and exercise regularly to keep your heart healthy.

Habit Forming

No

Therapeutic Class

ANTICOAGULANT/ANTITHROMBOTIC

Product Substitutes

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Macdaxa 150 mg Capsule is a thrombin inhibitor. The inhibition of thrombin, reduces the formation of blood-clotting material fibrin, thereby leading to fewer clots and aiding the free flow of blood.

No, you are not recommended to stop taking Macdaxa 150 mg Capsule without consulting your doctor as it may worsen the condition. Therefore, take Macdaxa 150 mg Capsule for as long as your doctor has prescribed it.

Please consult your doctor if you are due to undergo surgery. The doctor might ask you to stop taking Macdaxa 150 mg Capsule a few days before surgery since it can cause an increased risk of bleeding during surgery.

Taking Macdaxa 150 mg Capsule during pregnancy may cause bleeding in the mother or the newborn baby. However, please consult your doctor if you are planning to become pregnant or already pregnant before starting Macdaxa 150 mg Capsule .

Macdaxa 150 mg Capsule may increase the risk of bleeding. It is advised to be cautious during your daily activities like shaving, cutting fingernails, or using sharp objects. Inform your doctor immediately if you notice any abnormal staining or bleeding.

Drug-Drug Interactions Checker List

  • WARFARIN
  • PHENPROCOUMON
  • ACENOCOUMAROL
  • HEPARIN
  • CLOPIDOGREL
  • PRASUGREL
  • TICAGRELOR
  • RIVAROXABAN
  • AMIODARONE
  • DRONEDARONE
  • QUINIDINE
  • VERAPAMIL
  • ITRACONAZOLE
  • KETOCONAZOLE
  • TACROLIMUS
  • CYCLOSPORINE
  • INDINAVIR
  • RITONAVIR
  • RIFAMPICIN
  • CLARITHROMYCIN
  • GLECAPREVIR
  • PIBRENTASVIR
  • IBUPROFEN
  • DICLOFENAC
  • PHENYTOIN
  • CARBAMAZEPINE

Special Advise

  • You should have regular platelet count, factor V assay, fibrinogen level test, prothrombin time test (PT or PT-INR), and the INR (international normalized ratio) to analyze your blood clotting time.

  • In case you miss a dose of Macdaxa 150 mg Capsule , take it as soon as possible. However, if it is too close to the next dose, revert to the original schedule.

Disease/Condition Glossary

Thrombosis/Blood Clot: A blood clot can occur in any part of the body and can lead to a heart attack, stroke, or damage to organs. Blood clots can reach the arteries or veins in the organs like the brain, kidney, heart, lungs, and limbs. Conditions like atherosclerosis, diabetes, heart failure, irregular heartbeat (arrhythmia), and obesity/overweight can trigger excessive blood clotting in the brain and heart. 

Deep vein thrombosis (blood clots in legs): It is a medical condition in which blood clots form in deep veins, usually in the legs. The symptoms include leg pain or swelling. 

Pulmonary embolism (blood clots in the lung): It is a chronic condition that occurs as the blood clots break and travel to the lungs from deep veins in the legs or other parts of the body. The symptoms of pulmonary embolism include cough, chest pain, and shortness of breath.

Stroke (blood clots in the brain): It occurs when the supply of blood to part of your brain is stopped or reduced. This prevents brain tissue from getting nutrients and oxygen leading to the death of brain cells.

Heart attack: A heart attack means the death of heart tissue due to a shortage of blood supply to the heart muscles. This can occur when there is an accumulation of cholesterol or fat narrowing the heart's major veins or when other substances like a blood clot are blocking the flow of blood. 

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