Macirol Tablet 10's
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MRP ₹1750
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₹1487*
MRP ₹1750
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Macirol Tablet 10's belongs to the class of 'anti-hypertensive drugs', primarily used to treat high blood pressure in the lungs' arteries (pulmonary arterial hypertension). Hypertension is a medical condition in which the blood exerts high pressure (force exerted by circulating blood) against the walls of blood vessels. This condition makes the heart work harder in pumping blood to the whole body. Pulmonary hypertension affects arteries in the lungs and the right side of the heart.
Macirol Tablet 10's contains 'macitentan', which works by inhibiting the action of Endothelin, a natural substance that constricts blood vessels and raises blood pressure. Macirol Tablet 10's widens the constricted pulmonary arteries (blood vessels that carry blood from the heart to the lungs) and increases blood supply, thus lowering blood pressure.
Take Macirol Tablet 10's as prescribed by your doctor. Your dose and duration of Macirol Tablet 10's will be advised by your doctor, depending upon your medical condition. In some cases, you may experience headaches, inflammation of the airways, and oedema. Most of these side effects of Macirol Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.
Please inform your doctor if you are using any prescription, or non-prescription drugs, including vitamins and herbal products. Before starting Macirol Tablet 10's, let your doctor know if you have allergic reactions to Macirol Tablet 10's or other medicines. Inform your doctor if you have low blood pressure, lung, heart, kidney, liver problems, and anaemia (lack of blood cells). It is advised to consult a doctor if you are a pregnant or breastfeeding mother. Do not stop taking Macirol Tablet 10's without consulting your doctor since it may worsen your condition and increase the risk of future heart problems. Do not consume alcohol with Macirol Tablet 10's as it may increase the risk of low blood pressure.
Macirol Tablet 10's is an anti-hypertensive medicine that treats high blood pressure in the lungs' arteries (pulmonary arterial hypertension (PAH)). It contains 'Macitentan,' which works by inhibiting the action of Endothelin, a natural substance that constricts blood vessels and raises blood pressure. In people with PAH, the pulmonary arteries get narrower making the heart work harder to pump blood through them. Macirol Tablet 10's widens these constricted arteries and makes it easier for the heart to pump blood, thus lowering the blood pressure.
Please inform your doctor beforehand if you are allergic to Macirol Tablet 10's or other medicines. Brief your medical history if you have heart failure, liver or kidney diseases, lung conditions (pulmonary fibrosis), anaemia, oedema (fluid retention) and hypotension (low blood pressure) before starting Macirol Tablet 10's. Macirol Tablet 10's is contraindicated during pregnancy since it harms the foetus. Please get a pregnancy test done before starting Macirol Tablet 10's. You should get a negative pregnancy test for sure before using Macirol Tablet 10's. Also, please use reliable forms of birth control if you are undergoing treatment with Macirol Tablet 10's to avoid pregnancy. Consult your doctor before using Macirol Tablet 10's if you are a breastfeeding mother. Complete the course strictly as the doctor advises, even if you feel better, to avoid the recurrence of the disease. Do not drive or operate machinery since Macirol Tablet 10's may cause side effects like dizziness and weakness, affecting your ability to concentrate and drive. Avoid consumption of alcohol with Macirol Tablet 10's as it may increase the risk of low blood pressure. Macirol Tablet 10's is not recommended in patients younger than 18 years of age.
Drug-Drug Interactions: Macirol Tablet 10's may interact with antibiotics (e.g. rifampicin, clarithromycin), a medicine used to treat seizures (e.g. phenytoin), a medicine used to treat depression and epilepsy (e.g. carbamazepine), medications used to treat HIV infections (e.g. ritonavir, saquinavir), anti-fungal medicines (e.g. fluconazole, itraconazole), a drug used to control the heartbeat (e.g. amiodarone), a medicine used to prevent organ rejection after transplant (e.g. cyclosporine), medications used to treat high blood pressure or specific heart problems (e.g. diltiazem, verapamil).
Drug-Food Interactions: Alcohol may increase the side effects of Macirol Tablet 10's. Hence, it is advised to limit the intake of alcohol while using Macirol Tablet 10's.
Drug-Disease Interactions: People with heart failure, liver or kidney diseases, lung conditions (pulmonary fibrosis), anaemia, oedema (fluid retention), low blood pressure, and severe dehydration should consult the doctor before taking Macirol Tablet 10's.
Pulmonary Arterial Hypertension: It is referred to as high blood pressure in the blood vessels (the pulmonary arteries) that carry blood from the heart to the lungs. It's a serious condition that can harm the heart's right side. The walls of the pulmonary arteries thicken and stiffen, making it difficult for blood to flow through. Because of the reduced blood flow, the right side of the heart has a harder time pumping blood through the arteries which may lead to heart failure. The common symptoms of pulmonary hypertension are shortness of breath, dizziness, palpitations, and chest pressure. It can affect people of all ages, but it is more common in people who already have a heart or lung problem.
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Alcohol
Caution
It is advised to limit alcohol intake since alcohol consumption with Macirol Tablet 10's may increase the risk of low blood pressure and cause adverse effects, such as dizziness, fainting, light-headedness or headache.
Pregnancy
Unsafe
Macirol Tablet 10's is not recommended in pregnancy. It can affect and harm the developing baby. You are advised to get a pregnancy test done before starting Macirol Tablet 10's. You should get a negative pregnancy test for sure before using Macirol Tablet 10's. Also, please use reliable forms of birth control if you are undergoing treatment with Macirol Tablet 10's to avoid pregnancy.
Breast Feeding
Caution
Consult your doctor, and there is no substantial research yet on the use of Macirol Tablet 10's in breastfeeding/nursing mothers.
Driving
Unsafe
Macirol Tablet 10's can cause side effects such as headaches and hypotension, and the symptoms of your condition can also make you less fit to drive.
Liver
Caution
Let your doctor know before taking Macirol Tablet 10's if you have any history of liver diseases or very high levels of liver enzymes in your blood. Your doctor will weigh the benefits and any potential risks before prescribing Macirol Tablet 10's.
Kidney
Caution
If you have kidney problems, talk to your doctor before using Macirol Tablet 10's. Macitentan may lead to more blood pressure reduction and a decrease in haemoglobin in patients with kidney problems. Please consult the doctor, and your doctor will weigh the benefits and any potential risks before prescribing Macirol Tablet 10's.
Children
Unsafe
Safety and effectiveness of Macirol Tablet 10's have not been established in patients below 18 years of age.
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