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About Macitent Tablet
Macitent Tablet belongs to the class of 'anti-hypertensive drugs', primarily used to treat high blood pressure in the lungs' arteries (pulmonary arterial hypertension). Hypertension is a medical condition in which the blood exerts high pressure (force exerted by circulating blood) against the walls of blood vessels. This condition makes the heart work harder in pumping blood to the whole body. Pulmonary hypertension affects arteries in the lungs and the right side of the heart.
Macitent Tablet contains 'macitentan', which works by inhibiting the action of Endothelin, a natural substance that constricts blood vessels and raises blood pressure. Macitent Tablet widens the constricted pulmonary arteries (blood vessels that carry blood from the heart to the lungs) and increases blood supply, thus lowering blood pressure.
Take Macitent Tablet as prescribed by your doctor. Your dose and duration of Macitent Tablet will be advised by your doctor, depending upon your medical condition. In some cases, you may experience headaches, inflammation of the airways, and oedema. Most of these side effects of Macitent Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.
Please inform your doctor if you are using any prescription, or non-prescription drugs, including vitamins and herbal products. Before starting Macitent Tablet , let your doctor know if you have allergic reactions to Macitent Tablet or other medicines. Inform your doctor if you have low blood pressure, lung, heart, kidney, liver problems, and anaemia (lack of blood cells). It is advised to consult a doctor if you are a pregnant or breastfeeding mother. Do not stop taking Macitent Tablet without consulting your doctor since it may worsen your condition and increase the risk of future heart problems. Do not consume alcohol with Macitent Tablet as it may increase the risk of low blood pressure.
Uses of Macitent Tablet
Directions for Use
Key Benefits
Macitent Tablet is an anti-hypertensive medicine that treats high blood pressure in the lungs' arteries (pulmonary arterial hypertension (PAH)). It contains 'Macitentan,' which works by inhibiting the action of Endothelin, a natural substance that constricts blood vessels and raises blood pressure. In people with PAH, the pulmonary arteries get narrower making the heart work harder to pump blood through them. Macitent Tablet widens these constricted arteries and makes it easier for the heart to pump blood, thus lowering the blood pressure.
Storage
Drug Warnings
Please inform your doctor beforehand if you are allergic to Macitent Tablet or other medicines. Brief your medical history if you have heart failure, liver or kidney diseases, lung conditions (pulmonary fibrosis), anaemia, oedema (fluid retention) and hypotension (low blood pressure) before starting Macitent Tablet . Macitent Tablet is contraindicated during pregnancy since it harms the foetus. Please get a pregnancy test done before starting Macitent Tablet . You should get a negative pregnancy test for sure before using Macitent Tablet . Also, please use reliable forms of birth control if you are undergoing treatment with Macitent Tablet to avoid pregnancy. Consult your doctor before using Macitent Tablet if you are a breastfeeding mother. Complete the course strictly as the doctor advises, even if you feel better, to avoid the recurrence of the disease. Do not drive or operate machinery since Macitent Tablet may cause side effects like dizziness and weakness, affecting your ability to concentrate and drive. Avoid consumption of alcohol with Macitent Tablet as it may increase the risk of low blood pressure. Macitent Tablet is not recommended in patients younger than 18 years of age.
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Disease/Condition Glossary
Pulmonary Arterial Hypertension: It is referred to as high blood pressure in the blood vessels (the pulmonary arteries) that carry blood from the heart to the lungs. It's a serious condition that can harm the heart's right side. The walls of the pulmonary arteries thicken and stiffen, making it difficult for blood to flow through. Because of the reduced blood flow, the right side of the heart has a harder time pumping blood through the arteries which may lead to heart failure. The common symptoms of pulmonary hypertension are shortness of breath, dizziness, palpitations, and chest pressure. It can affect people of all ages, but it is more common in people who already have a heart or lung problem.

Have a query?
Alcohol
Safe if prescribed
It is advised to limit alcohol intake since alcohol consumption with Macitent Tablet may increase the risk of low blood pressure and cause adverse effects, such as dizziness, fainting, light-headedness or headache.
Pregnancy
Consult your doctor
Macitent Tablet is not recommended in pregnancy. It can affect and harm the developing baby. You are advised to get a pregnancy test done before starting Macitent Tablet . You should get a negative pregnancy test for sure before using Macitent Tablet . Also, please use reliable forms of birth control if you are undergoing treatment with Macitent Tablet to avoid pregnancy.
Breast Feeding
Consult your doctor
Consult your doctor, and there is no substantial research yet on the use of Macitent Tablet in breastfeeding/nursing mothers.
Driving
Safe if prescribed
Macitent Tablet can cause side effects such as headaches and hypotension, and the symptoms of your condition can also make you less fit to drive.
Liver
Consult your doctor
Let your doctor know before taking Macitent Tablet if you have any history of liver diseases or very high levels of liver enzymes in your blood. Your doctor will weigh the benefits and any potential risks before prescribing Macitent Tablet .
Kidney
Consult your doctor
If you have kidney problems, talk to your doctor before using Macitent Tablet . Macitentan may lead to more blood pressure reduction and a decrease in haemoglobin in patients with kidney problems. Please consult the doctor, and your doctor will weigh the benefits and any potential risks before prescribing Macitent Tablet .
Children
Safe if prescribed
Safety and effectiveness of Macitent Tablet have not been established in patients below 18 years of age.
Recommended for a 30-day course: 3 Strips