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Reviewed By Sureshvarma D , MPharma
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Composition :

SORAFENIB-200MG

Manufacturer/Marketer :

Amps Biotech Biotech Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Mapsonib 200 Tablet 30's

Mapsonib 200 Tablet 30's belongs to the group of medicine called ‘anti-cancer’ that is primarily indicated in the treatment of kidney, liver, and thyroid cancer.  Kidney cancer is also known as renal cancer is a disease in which healthy cells of the kidney become malignant (cancerous), grow in an uncontrolled manner, and forms a tumour. Cancer of the liver is known as liver cancer. When cancer occurs in the liver, it destroys healthy cells of the liver and affects the ability of the liver to function normally. Thyroid cancer occurs when cells start multiplying in the thyroid gland and form a tumour. The tumour is a collection of abnormal cells.

Mapsonib 200 Tablet 30's contains 'Sorafenib' that falls in the category of medicines known as 'kinase inhibitors'. It works by stopping the action of an abnormal protein that causes the multiplication of cancerous cells. In this way, it stops the spread of cancerous cells.

Take Mapsonib 200 Tablet 30's as prescribed by your doctor. You are suggested to take Mapsonib 200 Tablet 30's as long as your doctor has prescribed it after checking your medical condition.  In some cases, you may experience certain common side-effects such as itching or skin rash, acne, dry skin, vomiting, diarrhoea, and loss of appetite. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

To treat your condition effectually, continue taking Mapsonib 200 Tablet 30's for as long as your doctor has prescribed. Do not take Mapsonib 200 Tablet 30's if you are pregnant or planning for pregnancy as Mapsonib 200 Tablet 30's causes serious birth defects. Mapsonib 200 Tablet 30's should not be taken by breastfeeding mothers as it passes into breast milk and may cause a possible risk to the infant. Elderly people are more sensitive to the medicine so the doctor may adjust the dosage according to the condition. Avoid consuming alcohol along with Mapsonib 200 Tablet 30's as it could lead to increased dizziness.

Uses of Mapsonib 200 Tablet 30's

 Cancer (kidney, liver, and thyroid)

Directions for Use

Take Mapsonib 200 Tablet 30's without food on an empty stomach at least one or two hours before taking a meal or take it as advised by a doctor. Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Mapsonib 200 Tablet 30's is a ' tyrosine kinase inhibitor (TKI)', that stops the uncontrolled growth and spread of cancerous cells. Mapsonib 200 Tablet 30's is effective in treating thyroid, liver and kidney cancer. It acts by stopping the action of the abnormal protein that is responsible for the multiplication of cancerous cells. Whenever a new healthy cell is formed it undergoes a usual process of maturity. Cancerous cells form new cells more quickly so Mapsonib 200 Tablet 30's targets cancerous cells and block the action of Tyrosine kinases enzymes (responsible for causing cancer). In this way, Mapsonib 200 Tablet 30's stops the production, spread and growth of cancerous cells in the body.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Mapsonib 200 Tablet 30's

  • Acne
  • Dry skin
  • Nausea
  • Vomiting
  • Diarrhea
  • Loss of appetite
  • Itching or skin rash

Drug Warnings

Mapsonib 200 Tablet 30's may make you more susceptible to infections; consult your doctor if you develop any signs of infections such as fever, sore throat, breathlessness, jaundice, unexplained bleeding, or bruising. Your doctor may advise you to undergo regular blood tests, kidney and liver tests to monitor your condition. Inform your doctor about your health condition and medicines to rule out any unpleasant side-effects. Before your doctor prescribes you Mapsonib 200 Tablet 30's, tell them if you have heart problems, high blood pressure, bleeding issues, surgery, or an electrolyte imbalance (like abnormal levels of magnesium, calcium,  or potassium in the blood). Mapsonib 200 Tablet 30's is restricted to use in persons who are sensitive to any of its constituent or have squamous cell lung cancer or already taking carboplatin and paclitaxel.
 

Drug-Drug Interactions

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SorafenibPimozide
Critical
SorafenibZiprasidone
Critical

Drug-Drug Interactions

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SorafenibPimozide
Critical
How does the drug interact with Mapsonib 200 Tablet:
Using Pimozide together with Mapsonib 200 Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Mapsonib 200 Tablet with Pimozide can cause an interaction, consult a doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop any medication without consulting a doctor.
SorafenibZiprasidone
Critical
How does the drug interact with Mapsonib 200 Tablet:
Co-administration of Mapsonib 200 Tablet with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Mapsonib 200 Tablet with Ziprasidone together can result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
SorafenibMesoridazine
Critical
How does the drug interact with Mapsonib 200 Tablet:
Using mesoridazine together with Mapsonib 200 Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Mesoridazine with Mapsonib 200 Tablet can cause an interaction, please consult a doctor before taking it. However, if you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations call a doctor. Do not stop using any medications without consulting a doctor.
SorafenibSparfloxacin
Critical
How does the drug interact with Mapsonib 200 Tablet:
Coadministration of Mapsonib 200 Tablet with Sparfloxacin can prolong the QT interval (QT interval is a measurement made on an electrocardiogram used to assess some of the electrical properties of the heart) may result in additive effects and increased risk of ventricular arrhythmias (abnormal heart rhythm).

How to manage the interaction:
Co-administration of Sumatriptan with Sparfloxacin can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without talking to a doctor.
SorafenibDronedarone
Critical
How does the drug interact with Mapsonib 200 Tablet:
Using dronedarone together with Mapsonib 200 Tablet can increase the risk of an irregular heart rhythm. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Mapsonib 200 Tablet with Dronedarone is generally avoided as it can cause an interaction, consult a doctor before taking it. However, if you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations call a doctor. Do not stop using any medications without consulting a doctor.
SorafenibCarboplatin
Critical
How does the drug interact with Mapsonib 200 Tablet:
Co-administration of Mapsonib 200 Tablet with Carboplatin can increase the risk or severity of serious side effects.

How to manage the interaction:
Taking Mapsonib 200 Tablet with Carboplatin together is not recommended as it can cause an interaction, consult a doctor before taking it. However if you experience any unusual symptoms, consult the doctor. Do not stop using any medications without consulting a doctor.
SorafenibSaquinavir
Critical
How does the drug interact with Mapsonib 200 Tablet:
Using saquinavir together with Mapsonib 200 Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although Mapsonib 200 Tablet and Saquinavir is not recommended as it leads to an interaction, contact a doctor before you take Mapsonib 200 Tablet. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
SorafenibThioridazine
Critical
How does the drug interact with Mapsonib 200 Tablet:
Using thioridazine together with Mapsonib 200 Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Mapsonib 200 Tablet with Thioridazine together is not recommended as it can cause an interaction, consult a doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
SorafenibPimozide
Critical
How does the drug interact with Mapsonib 200 Tablet:
Using Pimozide together with Mapsonib 200 Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Mapsonib 200 Tablet with Pimozide can cause an interaction, consult a doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
SorafenibBepridil
Severe
How does the drug interact with Mapsonib 200 Tablet:
Coadministration of Bepridil with Mapsonib 200 Tablet can increase the risk of irregular heart rhythms.

How to manage the interaction:
Taking Bepridil with Mapsonib 200 Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or irregular heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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SORAFENIB-200MGHigh fat foods
Moderate

Drug-Food Interactions

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SORAFENIB-200MGHigh fat foods
Moderate
Common Foods to Avoid:
Frozen Meals, Cheese, Red Meat, Potato Chips, Hamburgers, Hot Dogs, Ice Cream

How to manage the interaction:
Food may reduce the oral absorption and bioavailability of Mapsonib 200 Tablet. Avoid taking Mapsonib 200 Tablet with high fat foods.

Diet & Lifestyle Advise

  • Physical activity helps in strengthening muscles reduce fatigue, helps in weight loss, and give strength. Gentle activities like 20-30minutes of walking or swimming would be helpful.
  • Performing yoga and other relaxation techniques may also help in improving physical and mental health and may reduce your stress levels.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep as resting helps in improving your health, mental ability, and improves attention.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath, or listen to soothing music.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing fibre help in better digestion. These include beans, peas, lentils, whole grains,  nuts, and seeds.
  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

Mapsonib 200 Tablet 30's Substitute

Substitutes safety advice
  • Soranib Tablet 30's

    by Others

    75.11per tablet
  • Sorafenat 200 mg Tablet 60's

    by AYUR

    65.12per tablet
  • Sorafenat Tablet 30's

    by AYUR

    70.50per tablet
  • Cadsonib Tablet

    by Others

    56.57per tablet
  • Adtrinib 200mg Tablet

    by Others

    70.50per tablet

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Mapsonib 200 Tablet 30's is safe to be taken by a diabetic person. However, take Mapsonib 200 Tablet 30's only after asking with a doctor as they may adjust the dosing according to the condition of the patient.

Mapsonib 200 Tablet 30's is restricted to use in pregnancy. A woman needs to have a negative pregnancy test before starting treatment with this medicine. It is better to use effective birth control methods to prevent pregnancy while taking this medicine or for at least 6 months after taking the last dose of Mapsonib 200 Tablet 30's.

Mapsonib 200 Tablet 30's should be stopped in cases where a person faces a serious side effect that affects the quality of life. Otherwise, you need to keep taking Mapsonib 200 Tablet 30's until your doctor asks you to stop it.

Liver cancer may spread fast depending upon the type of cancer. Hemangiosarcoma and angiosarcoma (the type of liver cancer) spread quickly while hepatocellular carcinoma spreads slowly in the disease.

Before your doctor prescribes you Mapsonib 200 Tablet 30's, tell them if you have heart problems, high blood pressure, bleeding issues, surgery, or an electrolyte imbalance (like abnormal levels of magnesium, calcium, or potassium in the blood).

Mapsonib 200 Tablet 30's is restricted to use in persons who are sensitive to any of its constituents or have squamous cell lung cancer or already taking carboplatin and paclitaxel.

If you are going for surgery tell your dentist ahead that you are taking this medicine. You need to stop taking it at least 10 days after having surgery.

Drug-Drug Interactions Checker List

  • SORAFENIB
  • PACLITAXEL
  • NEOMYCIN
  • CARBAMAZEPINE
  • PHENYTOIN
  • OMEPRAZOLE

Special Advise

  • Seek medical attention immediately if you have swelling in your lower legs,  fast heartbeats, or trouble breathing. It may be a sign of a heart problem.
  • Mapsonib 200 Tablet 30's may cause bleeding so tell your doctor if you see blood in urine or stools.

Disease/Condition Glossary

Cancer: It is a genetic change in which our cells divide uncontrollably and spread into surrounding tissues. There are two types of cancer, namely benign (localized) and metastatic (spread to the whole body). There are more than 100 types of cancer, including blood cancer, lung cancer, breast cancer, etc. Cancer growth can be prevented by chemotherapy (by strong antibiotics), radiation and stem cell therapy. To date, there is no cure for cancer.

Renal cancer: Kidneys help to get rid of waste by filtering blood, regulate fluid balance, and helps in making urine. Kidney cancer occurs when cancerous cells start growing uncontrollably in the kidneys.

Liver cancer: The liver is responsible for making bile that is a substance that helps in digesting fats, nutrients, and other vitamins. When the liver gets infected with cancerous cells, it destroys the liver cells and affects the ability of the liver to work properly.

Thyroid cancer: The thyroid is the gland of the body that produces hormones responsible for the functioning of the body. When thyroid cancer occurs when a person does not remain able to feel the thyroid gland.

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