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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

Online payment accepted

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Manufacturer/Marketer

Adley Pharmaceuticals Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About MDS-O 200 mg Tablet

MDS-O 200 mg Tablet belongs to the group of anti-cancer medicines called demethylation agents indicated for continued treatment of acute myeloid leukaemia in adults who improved after chemotherapy but could not complete intensive curative therapy. Acute myeloid leukaemia is a type of cancer that forms in the blood-forming cells of the bone marrow.

MDS-O 200 mg Tablet contains Azacitidine, which works by interfering with the growth of cancer cells, which are eventually destroyed by the body. It helps the bone marrow in the production of normal blood cells and kills abnormal cells in the bone marrow.
 
In some cases, MDS-O 200 mg Tablet may cause side effects such as nausea, vomiting, diarrhoea, constipation, fatigue and abdominal pain. Most of these side effects may not require medical attention and resolve gradually over time. Do not be reluctant to talk with your doctor if any of the side effects persist or worsen.
 
Do not use MDS-O 200 mg Tablet if you are pregnant or breastfeeding. Consult a doctor immediately if you become pregnant during treatment with MDS-O 200 mg Tablet . This medicine is not recommended for children as safety and effectiveness have not been established. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

Uses of MDS-O 200 mg Tablet

Acute myeloid leukaemia

Directions for Use

Take MDS-O 200 mg Tablet with or without food. Swallow the medicine as a whole with water; do not crush or chew it.

Medicinal Benefits

MDS-O 200 mg Tablet belongs to the group of anti-cancer medicines called demethylation agents indicated for continued treatment of adult patients with acute myeloid leukaemia who achieved first complete remission (all signs and symptoms of cancer have disappeared) or complete remission with incomplete blood count recovery following intensive induction chemotherapy and are not able to complete intensive curative therapy. MDS-O 200 mg Tablet contains Azacitidine, a nucleoside metabolic inhibitor which works by interfering with the growth of cancer cells, which are eventually destroyed by the body. It helps the bone marrow in the production of normal blood cells and kills abnormal cells in the bone marrow.

Storage

Store in a cool and dry place away from sunlight

Side Effects of MDS-O 200 mg Tablet

  • Nausea
  • Vomiting
  • Diarrhoea
  • Constipation
  • Dizziness
  • Fatigue
  • Abdominal pain
  • Decreased appetite
  • Arthralgia (joint pain)

Drug Warnings

Do not take MDS-O 200 mg Tablet if you are allergic to any of its components or if you are breastfeeding. Inform the doctor if you have liver or kidney problems. Seek medical attention if you experience symptoms of neutropenia/low white blood cells (fever or chills, feeling very tired or weak, body aches, and unusual headache) or thrombocytopenia/low platelet count (unusual bleeding or bruising). Consult the doctor if you are pregnant, plan to become pregnant, or if you plan to father a child.

Drug-Drug Interactions

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AzacitidineYellow fever vaccine
Critical
AzacitidineLeflunomide
Severe

Drug-Drug Interactions

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AzacitidineYellow fever vaccine
Critical
How does the drug interact with MDS-O 200 mg Tablet:
Taking Yellow fever vaccine with MDS-O 200 mg Tablet can increase the risk of infection.

How to manage the interaction:
Although there is a possible interaction between MDS-O 200 mg Tablet and the Yellow fever vaccine, you can take these medicines together if prescribed by a doctor. If you notice any signs of infection, it's important to contact a doctor right away. Do not stop using any medications without consulting a doctor.
AzacitidineLeflunomide
Severe
How does the drug interact with MDS-O 200 mg Tablet:
Taking MDS-O 200 mg Tablet and leflunomide together may increase the chances of developing severe infections.

How to manage the interaction:
Although there is an interaction between leflunomide and MDS-O 200 mg Tablet, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience fatigue, dizziness, lightheadedness, unusual bleeding or bruising, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting a doctor.
AzacitidineDeferiprone
Severe
How does the drug interact with MDS-O 200 mg Tablet:
Taking MDS-O 200 mg Tablet with Deferiprone can increase the risk of developing serious infections.

How to manage the interaction:
Co-administration of MDS-O 200 mg Tablet with Deferiprone can result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you have a fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination. Do not stop using any medications without talking to a doctor.
AzacitidineEfalizumab
Severe
How does the drug interact with MDS-O 200 mg Tablet:
Using efalizumab together with MDS-O 200 mg Tablet may increase the risk of serious infections.

How to manage the interaction:
Taking MDS-O 200 mg Tablet with Efalizumab together can result in an interaction, but it can be taken if a doctor has advised it. If you have any of these symptoms - complications, infection, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, pain or burning during urination - make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.
AzacitidineThalidomide
Severe
How does the drug interact with MDS-O 200 mg Tablet:
Taking thalidomide together with MDS-O 200 mg Tablet may increase the risk of blood clots and other complications.

How to manage the interaction:
Although taking thalidomide and MDS-O 200 mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
AzacitidineGolimumab
Severe
How does the drug interact with MDS-O 200 mg Tablet:
Taking MDS-O 200 mg Tablet with Golimumab can raise the risk of severe infections.

How to manage the interaction:
Co-administration of MDS-O 200 mg Tablet with Golimumab can result in an interaction, but it can be taken if a doctor has advised it. However, if you have any of these symptom's fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, pain or burning while peeing - make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.
AzacitidineBCG vaccine
Severe
How does the drug interact with MDS-O 200 mg Tablet:
Taking BCG vaccine with MDS-O 200 mg Tablet can increase the risk of infection.

How to manage the interaction:
Co-administration of MDS-O 200 mg Tablet with BCG vaccine can result in an interaction, but it can be taken if a doctor has advised it. If you notice any signs of infection, it's important to contact a doctor right away. Do not stop using any medications without consulting a doctor.
AzacitidineFingolimod
Severe
How does the drug interact with MDS-O 200 mg Tablet:
The use of fingolimod in conjunction with MDS-O 200 mg Tablet may raise the risk of severe infections.

How to manage the interaction:
Co-administration of MDS-O 200 mg Tablet with Fingolimod can possibly result in an interaction, but it can be taken if your doctor has advised it. However, Consult a doctor immediately if you have a fever, chills, diarrhoea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination. Do not discontinue any medications without consulting a doctor.
AzacitidineTofacitinib
Severe
How does the drug interact with MDS-O 200 mg Tablet:
Taking MDS-O 200 mg Tablet with tofacitinib can increase the risk of developing serious infections.

How to manage the interaction:
Although there is a possible interaction between MDS-O 200 mg Tablet and Tofacitinib, you can take these medicines together if prescribed by a doctor. However, consult a doctor immediately if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or irritated skin, body sores, or discomfort or burning during urination. Do not discontinue any medications without consulting a doctor.
AzacitidineCertolizumab
Severe
How does the drug interact with MDS-O 200 mg Tablet:
Taking MDS-O 200 mg Tablet with Certolizumab may raise the risk of severe infections.

How to manage the interaction:
Co-administration of MDS-O 200 mg Tablet with Certolizumab can result in an interaction, but it can be taken if a doctor has advised it. However, if you have any of these symptom's fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, pain or burning while peeing - make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly as it helps maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include vegetables and fruits in your diet.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugar.
  • Get optimal sleep; rest well.
  • Drink enough water and eat fibre-rich foods, vegetables and fruits.

Habit Forming

No

Therapeutic Class

CHEMOTHERAPY

MDS-O 200 mg Tablet Substitute

Substitutes safety advice
  • Azatend-O 200 mg Tablet 14's

    by Others

    1158.31per tablet
  • Xpreza 200 mg Tablet 14's

    by Others

    937.14per tablet
  • MDS-O 200mg Tablet

    by Others

    425.23per tablet

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Special Advise

  • If you are a female, you should take a pregnancy test prior to the start of the treatment. Use reliable contraception to prevent pregnancy during treatment and for 6 months after the last dose.
  • Male patients with partners of reproductive potential should use effective contraception during treatment and for 3 months after stopping the treatment.
  • If the powder from the medicine comes in contact with your skin, wash the area well with soap and water immediately.
  • If the powder from the medicine comes in contact with mucous membranes (eyes or mouth), flush the area with water immediately.

Disease/Condition Glossary

Acute myeloid leukaemia: Acute myeloid leukaemia, also called acute myelogenous leukaemia or acute nonlymphocytic leukaemia, is the cancer of blood and bone marrow with excess immature white blood cells. Symptoms include fever, recurrent infections, fatigue, and easy bruising.

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