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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Non returnable*
COD available

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Composition :

HEPARIN-1000IU

Manufacturer/Marketer :

Ellan Pharma

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About Medhep Injection 5 ml

Medhep Injection 5 ml belongs to a class of drugs called anticoagulants or blood thinners. Medhep Injection 5 ml is primarily used to prevent and treat deep vein thrombosis (blood clots in leg veins), pulmonary embolism (blood clots in the lung), stroke, Transient ischaemic attack (TIA), and heart attacks.  Deep vein thrombosis is a medical condition in which blood clots form in deep veins usually in the legs. Pulmonary embolism is a condition in which a blood clot blocks the arteries in the lungs. A stroke is a condition where a blood clot restricts the flow of blood to your brain, causing brain cells to die and possibly resulting in permanent brain damage or death. Transient ischaemic attack (TIA) is a condition also called 'mini-strokes', these have similar symptoms to a stroke, but the effects usually last less than 24 hours. Heart attack is a condition where a blood clot blocks a blood vessel supplying your heart, starving it of oxygen and causing chest pain and sometimes death.

Blood clots are formed to stop bleeding that occurs due to tissue injury. Though blood clots are useful to stop bleeding, they may be harmful when abnormally formed within blood vessels as they block blood vessels and inhibit blood flow to essential organs such as the brain, heart, or lungs. Medhep Injection 5 ml works by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot) preventing blood clot formation.

Medhep Injection 5 ml will be administered by a healthcare professional; do not self-administer. Some people may experience hemorrhage, thrombocytopenia (low platelets), hypersensitivity reactions, and elevations of liver enzyme (aminotransferase) levels. Most of these side effects of Medhep Injection 5 ml do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Medhep Injection 5 ml or any other medicines, please tell your doctor. It is not known whether Medhep Injection 5 ml harms the baby or passes into breast milk in pregnancy and breastfeeding state. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Medhep Injection 5 ml. Medhep Injection 5 ml is not recommended for children below 2 months of age. If you have diabetes, kidney or liver problems, bleeding problems, or are aged above 60 years, inform your doctor before taking Medhep Injection 5 ml.

Uses of Medhep Injection 5 ml

Prevention of blood clots.

Directions for Use

Medhep Injection 5 ml will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Medhep Injection 5 ml is primarily used to prevent and treat blood clots by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot). Medhep Injection 5 ml also reduces the risk of blood clots during surgeries (like heart surgery). Medhep Injection 5 ml is used as an anticoagulant in blood transfusion and in a dialysis procedure.

Storage

Keep Medhep Injection 5 ml out of the sight and reach of children.
Side effects of Medhep Injection 5 ml
  • Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
  • Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
  • Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
  • Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
  • If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
  • In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
  • Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
  • If you experience severe bleeding or bruising, seek emergency medical attention immediately.

Drug Warnings

Use Medhep Injection 5 ml cautiously in conditions with increased risk of bleeding. Use of name contraindicated in patients with HIT - Heparin-induced thrombosis (the abnormal formation of blood clots inside a blood vessel) and HITT (heparin-induced thrombocytopenia and thrombosis) might occur. Monitoring of blood coagulation tests like platelet count and haematocrit should be done in all patients receiving Medhep Injection 5 ml. Patients should inform the doctor that they are receiving Medhep Injection 5 ml before any surgery is scheduled.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Medhep Injection 5 ml:
Taking Alteplase with Medhep Injection 5 ml can increase the risk of bleeding.

How to manage the interaction:
Taking Medhep Injection 5 ml with Alteplase is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you have unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Medhep Injection 5 ml:
Taking Tenecteplase with Medhep Injection 5 ml can increase the risk of bleeding.

How to manage the interaction:
Taking Medhep Injection 5 ml with Tenecteplase is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you notice unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
HeparinOritavancin
Critical
How does the drug interact with Medhep Injection 5 ml:
Using Medhep Injection 5 ml with Oritavancin can make Medhep Injection 5 ml less effective as a therapy.

How to manage the interaction:
Medhep Injection 5 ml is not recommended within 120 hours (5 days) of taking oritavancin. Oritavancin can interfere with certain of the major coagulation tests used to assess Medhep Injection 5 ml's effectiveness and safety, it can be taken only if prescribed by a doctor. Do not discontinue any medications without a doctor's advice.
HeparinBazedoxifene
Critical
How does the drug interact with Medhep Injection 5 ml:
When Medhep Injection 5 ml is taken with bazedoxifene the effects of Medhep Injection 5 ml are reduced by bazedoxifene.

How to manage the interaction:
Taking Bazedoxifene with Medhep Injection 5 ml is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Medhep Injection 5 ml:
Taking Ticlopidine with Medhep Injection 5 ml can increase the risk of bleeding.

How to manage the interaction:
Taking Ticlopidine with Medhep Injection 5 ml is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Medhep Injection 5 ml:
Taking Mifepristone with Medhep Injection 5 ml can increase the risk of negative side effects.

How to manage the interaction:
Taking Medhep Injection 5 ml with Mifepristone is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Medhep Injection 5 ml:
Taking Medhep Injection 5 ml with Urokinase can increase the risk of bleeding.

How to manage the interaction:
Co-administration of Medhep Injection 5 ml with Urokinase can result in an interaction, but it can be taken if a doctor has advised it. However, if you have unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Medhep Injection 5 ml:
Sulfadiazine enhances the effects of Medhep Injection 5 ml by slowing its breakdown.

How to manage the interaction:
Co-administration of Sulfadiazine with Medhep Injection 5 ml can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without talking to a doctor.
How does the drug interact with Medhep Injection 5 ml:
Co-administration of Cefpodoxime with Medhep Injection 5 ml may enhance the levels or effects of Medhep Injection 5 ml by anticoagulation (preventing blood from clotting).

How to manage the interaction:
Although there is an interaction, Cefpodoxime can be taken with Medhep Injection 5 ml if prescribed by the doctor. Do not stop using any medications without a doctor's advice. Do not discontinue the medication without consulting a doctor.
HeparinDicoumarol
Severe
How does the drug interact with Medhep Injection 5 ml:
Coadministration of Medhep Injection 5 ml and dicumarol may increase the risk of bleeding.

How to manage the interaction:
Although taking Medhep Injection 5 ml and Dicoumarol together can cause an interaction, it can be taken if a doctor has suggested it. However, if you have unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, contact a doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

ANTICOAGULANTS / ANTITHROMBOTICS. ANTICONVULSANTS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

No, you are not recommended to take ibuprofen with Medhep Injection 5 ml as co-administration of these two medicines may increase the risk of bleeding more easily. However, please consult a doctor before taking other medicines with Medhep Injection 5 ml.

Yes, Medhep Injection 5 ml may increase potassium levels in the blood (hyperkalaemia), especially when given for a long period. Therefore, it is advised to inform your doctor if you are taking any medicines that increase potassium levels in the blood.

Yes, Medhep Injection 5 ml may cause bleeding. If you notice purple spots on the skin or unusual bruising, blood in urine, black tarry stools, unusual bleeding from gums or nose, please inform your doctor immediately as these are signs of bleeding more easily.

Yes, Medhep Injection 5 ml may cause allergic reactions such as fever, chills, difficulty in breathing, wheezing, blue shade to the lips, swelling of lips, and eyes. It is not necessary for everyone taking Medhep Injection 5 ml to experience an allergic reaction. However, if you notice any of these signs, please inform your doctor immediately.

Drug-Drug Interactions Checker List

  • SALICYLIC ACID
  • IBUPROFEN
  • INDOMETHACIN
  • PHENYLBUTAZONE
  • CELECOXIB
  • HYDROXYCHLOROQUINE
  • ABCIXIMAB
  • DIPYRIDAMOLE
  • DIGITALIS
  • TETRACYCLINE
  • NITROGLYCERIN

Special Advise

Regular blood tests are advised while taking Medhep Injection 5 ml to monitor prothrombin, platelets and coagulation time on regular basis.

Disease/Condition Glossary

Deep vein thrombosis (blood clots in legs) is a medical condition in which blood clots form in deep veins usually in the legs. The symptoms include leg pain or swelling.

Pulmonary embolism (blood clots in the lung) is a condition that occurs as the blood clots break and travel to the lungs from deep veins in the legs or other parts of the body. The symptoms of pulmonary embolism include chest pain, cough, and shortness of breath. 

Stroke is a condition where a blood clot restricts the flow of blood to your brain, causing brain cells to die and possibly resulting in permanent brain damage or death.

Transient ischaemic attack (TIA) is a condition also called 'mini-strokes', these have similar symptoms to a stroke, but the effects usually last less than 24 hours.

Heart attack is a condition where a blood clot blocks a blood vessel supplying your heart, starving it of oxygen and causing chest pain and sometimes death. Quick medication is advised to reduce the risk of serious conditions due to blood clots.

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