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  3. MEFQUE 250MG TABLET

Written By ,
Reviewed By Sunny S , MBBS
Non returnable*
COD available

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Composition :

MEFLOQUINE-250MG

Manufacturer/Marketer :

Zydus Healthcare Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About Mefque Tablet

Mefque Tablet comes into the category of 'Antimalarials' mainly used to treat or prevent malaria. Malaria is a life-threatening disease that is spread by the bite of an infected mosquito (anopheles mosquito). When an infected mosquito bites a healthy person, then it transmits the infections into the bloodstream, which after several days starts affecting the red blood cells & liver cells, breaking them in the process. Usually, an infected person starts noticing the symptoms of malaria within 10 days to 4 weeks after the infection that include shaking chills, high fever, profuse sweating, headache, nausea, vomiting, abdominal pain, diarrhea, anemia, muscle pain, convulsions, coma and bloody stools.

Mefque Tablet contains ‘mefloquine’, which acts by killing the malarial parasites. It works by enhancing the levels of heme in the blood. Haeme is a substance toxic to the malarial parasite. In this way, the parasite gets killed by its toxic by-products released during its metabolism of hemoglobin. This kills the parasite and prevents the infection from spreading.

Take Mefque Tablet as prescribed by your doctor. You are advised to take Mefque Tablet for as long as your doctor has prescribed it for you based on your medical condition. You may experience sleeping problems (bad dreams, sleepiness, unable to sleep), headache, dizziness, vertigo (loss of balance), itching, nausea, vomiting, stomach pain or diarrhoea. Most of these side effects of Mefque Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Before taking Mefque Tablet, please inform your doctor if you have any allergy to Mefque Tablet or its active part. Mefque Tablet should not be taken in conditions like liver disease, kidney disease, eye problems and epilepsy/ fits disorder. Mefque Tablet should not be given to children less than 3 months. If you are pregnant or breastfeeding, please inform your doctor before taking Mefque Tablet. Do not drive or use a machine while taking Mefque Tablet as it causes dizziness. If you have some tolerance for sugar, you should not take Mefque Tablet. Contact your doctor before taking Mefque Tablet.

Uses of Mefque Tablet

Malaria

Directions for Use

Take Mefque Tablet preferably after a meal or as advised by your doctor. Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Mefque Tablet falls into a group of medicines known as antimalarials, which are indicated for treating or preventing malaria. Mefque Tablet contains mefloquine, which is quinoline medicine, that works by enhancing the levels of heme in the blood. Haeme is a substance toxic to the malarial parasite. In this way, the parasite gets killed by its toxic by-products released during its metabolism of hemoglobin. This kills the parasite and prevents the infection from spreading.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Mefque Tablet should not be taken in conditions like epilepsy/fits, heart problems, liver/ kidney disease, eye problems, inflammation in the lungs, and low blood sugar level. Before taking Mefque Tablet inform your doctor if you have suicidal thoughts, severe anxiety, abnormal dreams, insomnia (difficulty in sleeping), depression, feeling restless and confusion. Before taking Mefque Tablet, please inform your doctor if you have any allergy to Mefque Tablet or its active part Mefque Tablet should not be given to children less than 3 months. If you are pregnant or breastfeeding, please inform your doctor before taking Mefque Tablet. Do not drive or use a machine while taking Mefque Tablet as it causes dizziness. If you have some tolerance for sugar, you should not take Mefque Tablet. Contact your doctor before taking Mefque Tablet.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Mefque Tablet:
Taking Mefque Tablet with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Mefque Tablet with Ziprasidone is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Mefque Tablet:
Coadministration of Mefque Tablet and ketoconazole can increase the blood levels and can result in a possibly harmful heart rhythm irregularity.

How to manage the interaction:
Although taking Ketoconazole and Mefque Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you have sudden dizziness, lightheadedness, fainting, or fast or pounding heartbeats, you should consult a doctor immediately. Ketoconazole should not be taken with Mefque Tablet or within 15 weeks of your last dose of Mefque Tablet. Do not stop using any medications without a doctor's advice.
How does the drug interact with Mefque Tablet:
The combined use of Mefque Tablet and Disopyramide can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Mefque Tablet and Disopyramide can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Mefque Tablet:
The combined use of Mefque Tablet and Olanzapine can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Mefque Tablet and Olanzapine can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Mefque Tablet:
Combining Mefque Tablet with Galantamine can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Galantamine with Mefque Tablet together can result in an interaction, but it can be taken if your doctor has advised it. If you experience symptoms like a very slow heart rate, low blood pressure, dizziness, fainting, or an irregular heartbeat, call your doctor right away. Do not stop using any medications without talking to a doctor.
How does the drug interact with Mefque Tablet:
Coadministration of Ivabradine with Mefque Tablet can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Ivabradine with Mefque Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Mefque Tablet:
Taking oxytocin with Mefque Tablet can increase the risk of irregular heart rhythm.

How to manage the interaction:
Co-administration of Oxytocin with Mefque Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience if you develop sudden dizziness, lightheadedness, fainting, shortness of breath contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Mefque Tablet:
Taking Gatifloxacin with Mefque Tablet can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Gatifloxacin with Mefque Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Mefque Tablet:
Using Mefque Tablet together with sotalol can increase the risk of an irregular heart rhythm. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Although there is a possible interaction between Sotalol and Mefque Tablet, you can take these medicines together if prescribed by a doctor. If you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations consult a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Mefque Tablet:
Using Moxifloxacin together with Mefque Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
There may be a possibility of interaction between Moxifloxacin and Mefque Tablet, but it can be taken if prescribed by a doctor. If you experience irregular heart rhythm, dizziness, or difficulty breathing, contact a doctor right away. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A person should take nutritious food as when a person has a malarial fever, their body's requirement gets increased, and also taking high carbohydrate diet, Fresh fruits and vegetables help in recovering the body fast.
  • During fever, a person may experience appetite loss, thus eating food becomes a challenge. To deal with this, one should drink glucose water, fresh fruit juices, coconut water, to supplying the body's requirements through liquids.
  • High malaria fever makes the body weak and reduces appetite to take food that helps to synthesize immune bodies and help the body deal with parasites.
  • A person should not take very high-fiber foods like green leafy vegetables, and fruits with thick skin, as the body is already in the healing stage and it also has to digest these complex foods.
  • Take proper rest, which helps the body to relax and heal faster.

Habit Forming

No

Therapeutic Class

ANTI- MALARIALS

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Mefque Tablet is safe if used in the dose and duration recommended by your doctor. Take it just as instructed and do not skip any dose. Follow your doctor's directions carefully and inform your doctor if any of the side effects disturb you.

No, do not stop taking Mefque Tablet without asking your doctor even if you are feeling better. Your symptoms may enhance before the infection is completely cured. Thus, for better and complete treatment, it is instructed to continue your treatment for the recommended duration.

It has been reported that taking Mefque Tablet for a long time may cause irreversible damage to the retina of your eye which can even lead to vision loss, so take this medicine for the time suggested by the doctor.

High fever with chills is the main symptom of malaria. The symptoms include feeling of cold and shivering, high fever, sweating. It also includes headache, nausea, body pain and weakness.

No, do not take antifungal (ketoconazole) with Mefque Tablet and for at least 15 weeks after you stop taking it. Serious, life-threatening side effects on your heart can occur. Consult your doctor for further advice.

Drug-Drug Interactions Checker List

  • CHLOROQUINE
  • QUINIDINE
  • QUININE
  • AMITRIPTYLINE
  • PHENOTHIAZINE
  • CARBAMAZEPINE
  • PHENYTOIN
  • PHENOBARBITAL
  • VALPROATE
  • RIFAMPICIN
  • PENICILLIN
  • KETOCONAZOLE
  • EFAVIRENZ
  • TRAMADOL
  • WARFARIN

Special Advise

  • Take Mefque Tablet as prescribed by your doctor, do not stop takin if you feel better.
  • Your doctor may advice regular eye check up, during the treatment with Mefque Tablet as it may cause damage to the retina.

Disease/Condition Glossary

Malaria: It is a life-threatening disease caused by parasites that enter the body through the bite of a mosquito. This is a common disease in countries like Africa, South America and Southeast Asia. This disease usually occurs when an infected mosquito (infected with the parasite 'Plasmodium', parasites are organisms that live in other living organisms for their survival) bites a healthy individual then this parasite gets transferred into the bloodstream and starts growing and destroying the red blood cells of the body. There are four parasites responsible for causing malaria that include Plasmodium vivax, P. ovale, P. malaria and P. falciparum. Generally, an infected person starts noticing the symptoms within 10 days to 4 weeks after the mosquito bite, which include shaking chills that can range from moderate to high fever, profuse sweating, headache, nausea, vomiting, abdominal pain, diarrhea, anemia, muscle pain, convulsions, coma and bloody stools.

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