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Reviewed By Sunny S , MBBS
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Composition :

MEFLOQUINE-250MG

Consume Type :

ORAL

Return Policy :

Not Returnable

About Rumef 250mg Tablet

Rumef 250mg Tablet comes into the category of 'Antimalarials' mainly used to treat or prevent malaria. Malaria is a life-threatening disease that is spread by the bite of an infected mosquito (anopheles mosquito). When an infected mosquito bites a healthy person, then it transmits the infections into the bloodstream, which after several days starts affecting the red blood cells & liver cells, breaking them in the process. Usually, an infected person starts noticing the symptoms of malaria within 10 days to 4 weeks after the infection that include shaking chills, high fever, profuse sweating, headache, nausea, vomiting, abdominal pain, diarrhea, anemia, muscle pain, convulsions, coma and bloody stools.

Rumef 250mg Tablet contains ‘mefloquine’, which acts by killing the malarial parasites. It works by enhancing the levels of heme in the blood. Haeme is a substance toxic to the malarial parasite. In this way, the parasite gets killed by its toxic by-products released during its metabolism of hemoglobin. This kills the parasite and prevents the infection from spreading.

Take Rumef 250mg Tablet as prescribed by your doctor. You are advised to take Rumef 250mg Tablet for as long as your doctor has prescribed it for you based on your medical condition. You may experience sleeping problems (bad dreams, sleepiness, unable to sleep), headache, dizziness, vertigo (loss of balance), itching, nausea, vomiting, stomach pain or diarrhoea. Most of these side effects of Rumef 250mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Before taking Rumef 250mg Tablet, please inform your doctor if you have any allergy to Rumef 250mg Tablet or its active part. Rumef 250mg Tablet should not be taken in conditions like liver disease, kidney disease, eye problems and epilepsy/ fits disorder. Rumef 250mg Tablet should not be given to children less than 3 months. If you are pregnant or breastfeeding, please inform your doctor before taking Rumef 250mg Tablet. Do not drive or use a machine while taking Rumef 250mg Tablet as it causes dizziness. If you have some tolerance for sugar, you should not take Rumef 250mg Tablet. Contact your doctor before taking Rumef 250mg Tablet.

Uses of Rumef 250mg Tablet

Malaria

Directions for Use

Take Rumef 250mg Tablet preferably after a meal or as advised by your doctor. Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Rumef 250mg Tablet falls into a group of medicines known as antimalarials, which are indicated for treating or preventing malaria. Rumef 250mg Tablet contains mefloquine, which is quinoline medicine, that works by enhancing the levels of heme in the blood. Haeme is a substance toxic to the malarial parasite. In this way, the parasite gets killed by its toxic by-products released during its metabolism of hemoglobin. This kills the parasite and prevents the infection from spreading.

Storage

Store in a cool and dry place away from sunlight
Side effects of Rumef 250mg Tablet
Managing Medication-Triggered Anxiety: A Comprehensive Approach:
  • Inform your doctor about your anxiety symptoms so that you doctor may explore potential drug interactions and alter your treatment plan.
  • Work with your doctor to adjust your medication regimen or dosage to minimize anxiety symptoms.
  • Reduce anxiety symptoms by practicing relaxation techniques like meditation, deep breathing, or yoga.
  • Regular self-care activities, such as exercise, healthy food, and adequate sleep, can assist control anxiety.
  • Surround yourself with a supportive network of friends, family, or a support group to help manage anxiety and stay motivated.
  • Regularly track anxiety symptoms and report any changes to your doctor to ensure your treatment plan is effective and adjusted as needed.
  • Concentration, stress and anxiety can be improved by meditation and deep breathing.
  • You can increase your energy, memory and capacity to avoid distractions by exercising regularly.
  • Avoiding multitasking is advised.
  • Fruits, vegetables, whole foods and oily fish help to improve your nutrition.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 step-by-step strategies to manage the side effect of "inability to sleep" caused by medication usage:
  • Prepare for a restful night's sleep: Develop a calming pre-sleep routine, like reading or meditation, to help your body relax and prepare for sleep.
  • Create a sleep-conducive Environment: Make bedroom a sleep haven by ensuring it is quiet, dark and calm.
  • Follow a Sleep Schedule: Go to bed and get up at the same time every day to help regulate your body's internal clock and increase sleep quality.
  • Try relaxing techniques like deep breathing, mindfulness meditation and any others.
  • Limit stimulating activities before bedtime: Avoid stimulating activities before bedtime to improve sleep quality.
  • Monitor Progress: Keep track of your sleep patterns to identify areas for improvement.
  • Consult a doctor if needed: If these steps don't improve your sleep, consult a doctor for further guidance and therapy.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Drug Warnings

Rumef 250mg Tablet should not be taken in conditions like epilepsy/fits, heart problems, liver/ kidney disease, eye problems, inflammation in the lungs, and low blood sugar level. Before taking Rumef 250mg Tablet inform your doctor if you have suicidal thoughts, severe anxiety, abnormal dreams, insomnia (difficulty in sleeping), depression, feeling restless and confusion. Before taking Rumef 250mg Tablet, please inform your doctor if you have any allergy to Rumef 250mg Tablet or its active part Rumef 250mg Tablet should not be given to children less than 3 months. If you are pregnant or breastfeeding, please inform your doctor before taking Rumef 250mg Tablet. Do not drive or use a machine while taking Rumef 250mg Tablet as it causes dizziness. If you have some tolerance for sugar, you should not take Rumef 250mg Tablet. Contact your doctor before taking Rumef 250mg Tablet.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Rumef 250mg Tablet:
Taking Rumef 250mg Tablet with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Rumef 250mg Tablet with Ziprasidone is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Rumef 250mg Tablet:
Coadministration of Rumef 250mg Tablet and ketoconazole can increase the blood levels and can result in a possibly harmful heart rhythm irregularity.

How to manage the interaction:
Although taking Ketoconazole and Rumef 250mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you have sudden dizziness, lightheadedness, fainting, or fast or pounding heartbeats, you should consult a doctor immediately. Ketoconazole should not be taken with Rumef 250mg Tablet or within 15 weeks of your last dose of Rumef 250mg Tablet. Do not stop using any medications without a doctor's advice.
How does the drug interact with Rumef 250mg Tablet:
The combined use of Rumef 250mg Tablet and Disopyramide can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Rumef 250mg Tablet and Disopyramide can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Rumef 250mg Tablet:
The combined use of Rumef 250mg Tablet and Olanzapine can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Rumef 250mg Tablet and Olanzapine can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Rumef 250mg Tablet:
Combining Rumef 250mg Tablet with Galantamine can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Galantamine with Rumef 250mg Tablet together can result in an interaction, but it can be taken if your doctor has advised it. If you experience symptoms like a very slow heart rate, low blood pressure, dizziness, fainting, or an irregular heartbeat, call your doctor right away. Do not stop using any medications without talking to a doctor.
How does the drug interact with Rumef 250mg Tablet:
Coadministration of Ivabradine with Rumef 250mg Tablet can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Ivabradine with Rumef 250mg Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Rumef 250mg Tablet:
Taking oxytocin with Rumef 250mg Tablet can increase the risk of irregular heart rhythm.

How to manage the interaction:
Co-administration of Oxytocin with Rumef 250mg Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience if you develop sudden dizziness, lightheadedness, fainting, shortness of breath contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Rumef 250mg Tablet:
Taking Gatifloxacin with Rumef 250mg Tablet can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Gatifloxacin with Rumef 250mg Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Rumef 250mg Tablet:
Using Rumef 250mg Tablet together with sotalol can increase the risk of an irregular heart rhythm. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Although there is a possible interaction between Sotalol and Rumef 250mg Tablet, you can take these medicines together if prescribed by a doctor. If you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations consult a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Rumef 250mg Tablet:
Using Moxifloxacin together with Rumef 250mg Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
There may be a possibility of interaction between Moxifloxacin and Rumef 250mg Tablet, but it can be taken if prescribed by a doctor. If you experience irregular heart rhythm, dizziness, or difficulty breathing, contact a doctor right away. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A person should take nutritious food as when a person has a malarial fever, their body's requirement gets increased, and also taking high carbohydrate diet, Fresh fruits and vegetables help in recovering the body fast.
  • During fever, a person may experience appetite loss, thus eating food becomes a challenge. To deal with this, one should drink glucose water, fresh fruit juices, coconut water, to supplying the body's requirements through liquids.
  • High malaria fever makes the body weak and reduces appetite to take food that helps to synthesize immune bodies and help the body deal with parasites.
  • A person should not take very high-fiber foods like green leafy vegetables, and fruits with thick skin, as the body is already in the healing stage and it also has to digest these complex foods.
  • Take proper rest, which helps the body to relax and heal faster.

Habit Forming

No

Therapeutic Class

ANTI- MALARIALS

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Rumef 250mg Tablet is safe if used in the dose and duration recommended by your doctor. Take it just as instructed and do not skip any dose. Follow your doctor's directions carefully and inform your doctor if any of the side effects disturb you.

No, do not stop taking Rumef 250mg Tablet without asking your doctor even if you are feeling better. Your symptoms may enhance before the infection is completely cured. Thus, for better and complete treatment, it is instructed to continue your treatment for the recommended duration.

It has been reported that taking Rumef 250mg Tablet for a long time may cause irreversible damage to the retina of your eye which can even lead to vision loss, so take this medicine for the time suggested by the doctor.

High fever with chills is the main symptom of malaria. The symptoms include feeling of cold and shivering, high fever, sweating. It also includes headache, nausea, body pain and weakness.

No, do not take antifungal (ketoconazole) with Rumef 250mg Tablet and for at least 15 weeks after you stop taking it. Serious, life-threatening side effects on your heart can occur. Consult your doctor for further advice.

Drug-Drug Interactions Checker List

  • CHLOROQUINE
  • QUINIDINE
  • QUININE
  • AMITRIPTYLINE
  • PHENOTHIAZINE
  • CARBAMAZEPINE
  • PHENYTOIN
  • PHENOBARBITAL
  • VALPROATE
  • RIFAMPICIN
  • PENICILLIN
  • KETOCONAZOLE
  • EFAVIRENZ
  • TRAMADOL
  • WARFARIN

Special Advise

  • Take Rumef 250mg Tablet as prescribed by your doctor, do not stop takin if you feel better.
  • Your doctor may advice regular eye check up, during the treatment with Rumef 250mg Tablet as it may cause damage to the retina.

Disease/Condition Glossary

Malaria: It is a life-threatening disease caused by parasites that enter the body through the bite of a mosquito. This is a common disease in countries like Africa, South America and Southeast Asia. This disease usually occurs when an infected mosquito (infected with the parasite 'Plasmodium', parasites are organisms that live in other living organisms for their survival) bites a healthy individual then this parasite gets transferred into the bloodstream and starts growing and destroying the red blood cells of the body. There are four parasites responsible for causing malaria that include Plasmodium vivax, P. ovale, P. malaria and P. falciparum. Generally, an infected person starts noticing the symptoms within 10 days to 4 weeks after the mosquito bite, which include shaking chills that can range from moderate to high fever, profuse sweating, headache, nausea, vomiting, abdominal pain, diarrhea, anemia, muscle pain, convulsions, coma and bloody stools.

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