Mela 3 Cream 15 gm is a skin-related medication primarily used to treat melasma (dark brown patch on skin). Melasma also known as chloasma or mask of pregnancy, is a common skin condition that causes brown patches on the face. It is more common in women than in men. The discolored (grey-brown) patches occur mostly on the forehead, chin, nose, and cheeks.

Mela 3 Cream 15 gm contains three medicines, namely: Hydroquinone (skin lightening or bleaching agent), Mometasone (corticosteroid), and Tretinoin (a form of Vitamin A or retinoids). Hydroquinone belongs to the class of skin lightening agents that works by decreasing the amount of melanin (a skin pigment) that is responsible for the darkening of the skin. Mometasone belongs to the class of corticosteroids that works by acting inside skin cells and inhibits the release of certain chemical messengers in the body that cause redness, itching, and swelling. Tretinoin belongs to the class of retinoids (man-made vitamin A) that works by increasing the renewal of skin cells, which helps in the natural exfoliation of the skin’s outer layers.

Mela 3 Cream 15 gm is only for external use. Use Mela 3 Cream 15 gm as prescribed. Avoid contact of Mela 3 Cream 15 gm with nose, mouth, eyes, ears, or vagina. Do not apply on a cut, open wound, or burn skin area. In case Mela 3 Cream 15 gm comes in contact with these areas accidentally, rinse with water thoroughly. Some people may experience skin pain, acne, redness, irritation, burning, itching, or stinging sensation of the skin. Most of these side effects of Mela 3 Cream 15 gm do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Mela 3 Cream 15 gm or any other medicines, please tell your doctor. If you are pregnant, a nursing mother, or planning for pregnancy, it is advised to consult a doctor before using Mela 3 Cream 15 gm. Mela 3 Cream 15 gm is not recommended for children below 12 years of age. Do not apply Mela 3 Cream 15 gm on ulcerated skin or wounds. Avoid sun exposure while using Mela 3 Cream 15 gm as it may make the skin more sensitive to sunlight and cause sunburn. Wear protective clothing and use sunscreen while going out to protect your skin from sunburn. Do not cover or wrap the treated area with a bandage unless advised by your doctor. Avoid smoking or going near naked flames as the fabric (bedding, clothing, dressings) that is in contact with Mela 3 Cream 15 gm catches fire and burns easily. If you have a sulfite allergy, asthma, rosacea (redness and often red, small, pus-filled bumps on the face), acne, skin thinning, perioral dermatitis (redness and swelling of the skin around the mouth), genital itching, chickenpox, diabetes, cold sores, ulcerated skin, warts, shingles (a viral infection causing painful rash), eczema (itchy, swelling of the skin) or any other skin condition, inform your doctor before taking Mela 3 Cream 15 gm.

Mela 3 Cream 15 gm is a combination of three drugs, namely: Hydroquinone, Mometasone, and Tretinoin. Hydroquinone belongs to the class of skin lightening agents that works by decreasing the amount of melanin (a skin pigment) that is responsible for the darkening of the skin. Mometasone is a corticosteroid that acts inside skin cells and inhibits the release of certain chemical messengers in the body that cause redness, itching, and swelling. When the skin reacts to any allergens, such chemicals are released normally. Tretinoin belongs to the class of retinoids (man-made vitamin A) that works by increasing the renewal of skin cells, which helps in the natural exfoliation of the skin’s outer layers. Also, tretinoin loosens the cells on the skin’s surface and unblocks pores by reducing the production of oil in the skin. Thereby, decreases pimples, whiteheads, and blackheads.

• Skin pain
• Acne
• Redness, irritation, burning, itching or stinging sensation of the skin

If you are allergic to Mela 3 Cream 15 gm or any other medicines, please tell your doctor. If you are pregnant, a nursing mother, or planning for pregnancy, it is advised to consult a doctor before using Mela 3 Cream 15 gm. Mela 3 Cream 15 gm is not recommended for children below 12 years of age. Do not apply Mela 3 Cream 15 gm on ulcerated skin or wounds. Avoid sun exposure while using Mela 3 Cream 15 gm as it may make the skin more sensitive to sunlight and cause sunburn. Do not cover or wrap the treated area with a bandage unless advised by your doctor. Avoid smoking or going near naked flames as the fabric (bedding, clothing, dressings) that is in contact with Mela 3 Cream 15 gm catches fire and burns easily. If you have a sulfite allergy, asthma, rosacea (redness and often red, small, pus-filled bumps on the face), acne, skin thinning, perioral dermatitis (redness and swelling of the skin around the mouth), genital itching, chickenpox, diabetes, cold sores, ulcerated skin, warts, shingles (a viral infection causing painful rash), eczema (itchy, swelling of the skin) or any other skin condition, inform your doctor before taking Mela 3 Cream 15 gm.

Drug-Drug Interaction: Mela 3 Cream 15 gm may interact with photosensitizing agents (aminolevulinic acid, porfirmer, verteporfin), topical antibiotics (benzoyl peroxide), retinoids (isotretinoin), psoralens (methoxsalen), sensitizer (methyl aminolevulinate), antiseptic (resorcinol), keratolytic agents (salicylic acid, sulfur).

Drug-Food Interaction: No interactions found.

Drug-Disease Interaction: If you have a sulfite allergy, asthma, rosacea (redness and often red, small, pus-filled bumps on the face), acne, skin thinning, perioral dermatitis (redness and swelling of the skin around the mouth), genital itching, chickenpox, diabetes, cold sores, ulcerated skin, warts, shingles (a viral infection causing painful rash), eczema (itchy, swelling of the skin) or any other skin condition, inform your doctor before taking Mela 3 Cream 15 gm.

• AMINOLEVULINIC ACID
• BENZOYL PEROXIDE
• ISOTRETINOIN
• METHOXSALEN
• SALICYLIC ACID
• PORFIRMER
• VERTEPORFIN
• METHYL AMINOLEVULINATE
• RESORCINOL
• SULFUR

• Avoid sun exposure while using Mela 3 Cream 15 gm as it may make the skin more sensitive to sunlight and cause sunburn. Wear protective clothing and use sunscreen while going out to protect your skin from sunburn.
• Regular exercise can improve your mood and self-esteem though it doesn’t clear spots. Take a shower immediately after finishing the exercise.
• Wear a wide-brimmed hat to protect your face from sun exposure.
• Avoid using skin products that cause irritation such as skin cleansers or shampoos, harsh soaps, hair removers or waxes, hair colors or permanent chemicals, and skin products with astringents, lime, spices, or alcohol.

• Avoid using Mela 3 Cream 15 gm for more than 6-8 weeks without a doctor’s advice. Please consult a dermatologist if the skin condition does not improve after 2-3 months of treatment with Mela 3 Cream 15 gm.
• Do not take Mela 3 Cream 15 gm by mouth. Mela 3 Cream 15 gm is for use only on the skin (topical use). Accidently if Mela 3 Cream 15 gm gets in your eyes or mouth, immediately rinse with cold water.
• Do not take Mela 3 Cream 15 gm if you allergic sulfa containing medicines and have asthma. It is better to contact a doctor in these conditions and take Mela 3 Cream 15 gm. 

Melasma: It is also known as chloasma, a common skin condition that causes brown patches on the face. The discolored (grey-brown) patches occur mostly on the forehead, chin, nose, and cheeks. Melasma may be caused due to sun exposure, hormone therapy, pregnancy, birth control pills, thyroid, or even stress. It is more common in women than in men. It may occur in pregnant women, due to hormonal changes during pregnancy and is called a ‘mask of pregnancy and fades away after pregnancy on its own or after stopping the usage of contraceptive pills. It can be treated by using skin lightening creams, topical steroids, dermabrasion, or chemical peels.