Hydroquinone+mometasone+tretinoin
About
Hydroquinone+mometasone+tretinoin is a skin-related medication primarily used to treat melasma (dark brown patch on skin). Melasma also known as chloasma or mask of pregnancy, is a common skin condition that causes brown patches on the face. It is more common in women than in men. The discolored (grey-brown) patches occur mostly on the forehead, chin, nose, and cheeks.
Hydroquinone+mometasone+tretinoin contains three medicines, namely: Hydroquinone (skin lightening or bleaching agent), Mometasone (corticosteroid), and Tretinoin (a form of Vitamin A or retinoids). Hydroquinone belongs to the class of skin lightening agents that works by decreasing the amount of melanin (a skin pigment) that is responsible for the darkening of the skin. Mometasone belongs to the class of corticosteroids that works by acting inside skin cells and inhibits the release of certain chemical messengers in the body that cause redness, itching, and swelling. Tretinoin belongs to the class of retinoids (man-made vitamin A) that works by increasing the renewal of skin cells, which helps in the natural exfoliation of the skin’s outer layers.
Hydroquinone+mometasone+tretinoin is only for external use. Use Hydroquinone+mometasone+tretinoin as prescribed. Avoid contact of Hydroquinone+mometasone+tretinoin with nose, mouth, eyes, ears, or vagina. Do not apply on a cut, open wound, or burn skin area. In case Hydroquinone+mometasone+tretinoin comes in contact with these areas accidentally, rinse with water thoroughly. Some people may experience skin pain, acne, redness, irritation, burning, itching, or stinging sensation of the skin. Most of these side effects of Hydroquinone+mometasone+tretinoin do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
If you are allergic to Hydroquinone+mometasone+tretinoin or any other medicines, please tell your doctor. If you are pregnant, a nursing mother, or planning for pregnancy, it is advised to consult a doctor before using Hydroquinone+mometasone+tretinoin. Hydroquinone+mometasone+tretinoin is not recommended for children below 12 years of age. Do not apply Hydroquinone+mometasone+tretinoin on ulcerated skin or wounds. Avoid sun exposure while using Hydroquinone+mometasone+tretinoin as it may make the skin more sensitive to sunlight and cause sunburn. Wear protective clothing and use sunscreen while going out to protect your skin from sunburn. Do not cover or wrap the treated area with a bandage unless advised by your doctor. Avoid smoking or going near naked flames as the fabric (bedding, clothing, dressings) that is in contact with Hydroquinone+mometasone+tretinoin catches fire and burns easily. If you have a sulfite allergy, asthma, rosacea (redness and often red, small, pus-filled bumps on the face), acne, skin thinning, perioral dermatitis (redness and swelling of the skin around the mouth), genital itching, chickenpox, diabetes, cold sores, ulcerated skin, warts, shingles (a viral infection causing painful rash), eczema (itchy, swelling of the skin) or any other skin condition, inform your doctor before taking Hydroquinone+mometasone+tretinoin.
Uses of Hydroquinone+mometasone+tretinoin
Medicinal Benefits
Hydroquinone+mometasone+tretinoin is a combination of three drugs, namely: Hydroquinone, Mometasone, and Tretinoin. Hydroquinone belongs to the class of skin lightening agents that works by decreasing the amount of melanin (a skin pigment) that is responsible for the darkening of the skin. Mometasone is a corticosteroid that acts inside skin cells and inhibits the release of certain chemical messengers in the body that cause redness, itching, and swelling. When the skin reacts to any allergens, such chemicals are released normally. Tretinoin belongs to the class of retinoids (man-made vitamin A) that works by increasing the renewal of skin cells, which helps in the natural exfoliation of the skin’s outer layers. Also, tretinoin loosens the cells on the skin’s surface and unblocks pores by reducing the production of oil in the skin. Thereby, decreases pimples, whiteheads, and blackheads.
Directions for Use
Storage
Side Effects of Hydroquinone+mometasone+tretinoin
- Skin pain
- Acne
- Redness, irritation, burning, itching or stinging sensation of the skin
In-Depth Precautions and Warning
Drug Warnings
If you are allergic to Hydroquinone+mometasone+tretinoin or any other medicines, please tell your doctor. If you are pregnant, a nursing mother, or planning for pregnancy, it is advised to consult a doctor before using Hydroquinone+mometasone+tretinoin. Hydroquinone+mometasone+tretinoin is not recommended for children below 12 years of age. Do not apply Hydroquinone+mometasone+tretinoin on ulcerated skin or wounds. Avoid sun exposure while using Hydroquinone+mometasone+tretinoin as it may make the skin more sensitive to sunlight and cause sunburn. Do not cover or wrap the treated area with a bandage unless advised by your doctor. Avoid smoking or going near naked flames as the fabric (bedding, clothing, dressings) that is in contact with Hydroquinone+mometasone+tretinoin catches fire and burns easily. If you have a sulfite allergy, asthma, rosacea (redness and often red, small, pus-filled bumps on the face), acne, skin thinning, perioral dermatitis (redness and swelling of the skin around the mouth), genital itching, chickenpox, diabetes, cold sores, ulcerated skin, warts, shingles (a viral infection causing painful rash), eczema (itchy, swelling of the skin) or any other skin condition, inform your doctor before taking Hydroquinone+mometasone+tretinoin.
Drug Interactions
Drug-Drug Interaction: Hydroquinone+mometasone+tretinoin may interact with photosensitizing agents (aminolevulinic acid, porfirmer, verteporfin), topical antibiotics (benzoyl peroxide), retinoids (isotretinoin), psoralens (methoxsalen), sensitizer (methyl aminolevulinate), antiseptic (resorcinol), keratolytic agents (salicylic acid, sulfur).
Drug-Food Interaction: No interactions found.
Drug-Disease Interaction: If you have a sulfite allergy, asthma, rosacea (redness and often red, small, pus-filled bumps on the face), acne, skin thinning, perioral dermatitis (redness and swelling of the skin around the mouth), genital itching, chickenpox, diabetes, cold sores, ulcerated skin, warts, shingles (a viral infection causing painful rash), eczema (itchy, swelling of the skin) or any other skin condition, inform your doctor before taking Hydroquinone+mometasone+tretinoin.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionInteraction of alcohol with Hydroquinone+mometasone+tretinoin is unknown. Please consult a doctor before consuming alcohol while using Hydroquinone+mometasone+tretinoin.
Pregnancy
cautionThe safety of Hydroquinone+mometasone+tretinoin in pregnant women is unknown and is given to a pregnant woman only if the doctor thinks benefits outweigh risks.
Breast Feeding
cautionIt is unknown whether Hydroquinone+mometasone+tretinoin is excreted in human milk. Please consult a doctor before using Hydroquinone+mometasone+tretinoin while breastfeeding.
Driving
safe if prescribedHydroquinone+mometasone+tretinoin usually does not affect your ability to drive or operate machinery.
Liver
cautionIf you have any concerns regarding the use of Hydroquinone+mometasone+tretinoin in patients with liver problems, please consult a doctor.
Kidney
cautionIf you have any concerns regarding the use of Hydroquinone+mometasone+tretinoin in patients with kidney problems, please consult a doctor.
Children
unsafeHydroquinone+mometasone+tretinoin is not recommended for children below 12 years of age, as the safety and effectiveness were not established.
Habit Forming
Diet & Lifestyle Advise
- Avoid sun exposure while using Hydroquinone+mometasone+tretinoin as it may make the skin more sensitive to sunlight and cause sunburn. Wear protective clothing and use sunscreen while going out to protect your skin from sunburn.
- Regular exercise can improve your mood and self-esteem though it doesn’t clear spots. Take a shower immediately after finishing the exercise.
- Wear a wide-brimmed hat to protect your face from sun exposure.
- Avoid using skin products that cause irritation such as skin cleansers or shampoos, harsh soaps, hair removers or waxes, hair colors or permanent chemicals, and skin products with astringents, lime, spices, or alcohol.
Special Advise
- Avoid using Hydroquinone+mometasone+tretinoin for more than 6-8 weeks without a doctor’s advice.
- Do not take Hydroquinone+mometasone+tretinoin by mouth. Hydroquinone+mometasone+tretinoin is for use only on the skin (topical use). Accidently if Hydroquinone+mometasone+tretinoin gets in your eyes or mouth, immediately rinse with cold water.
Patients Concern
Disease/Condition Glossary
Melasma: It is also known as chloasma, a common skin condition that causes brown patches on the face. The discolored (grey-brown) patches occur mostly on the forehead, chin, nose, and cheeks. Melasma may be caused due to sun exposure, hormone therapy, pregnancy, birth control pills, thyroid, or even stress. It is more common in women than in men. It may occur in pregnant women, due to hormonal changes during pregnancy and is called a ‘mask of pregnancy and fades away after pregnancy on its own or after stopping the usage of contraceptive pills. It can be treated by using skin lightening creams, topical steroids, dermabrasion, or chemical peels.
FAQs
Hydroquinone+mometasone+tretinoin contains Hydroquinone, Mometasone and Tretinoin. Hydroquinone is a skin lightening agent that works by decreasing the amount of melanin (a skin pigment) that is responsible for the darkening of the skin. Mometasone is a corticosteroid that acts inside skin cells and inhibits the release of certain chemical messengers in the body that cause redness, itching and swelling. Tretinoin belongs to the class of retinoids (man-made vitamin A) that works by increasing the renewal of skin cells which helps in natural exfoliation of skin’s outer layers.
Yes, Hydroquinone+mometasone+tretinoin may increase the skin sensitivity to sunlight in the treated areas. Therefore, avoid or limit exposure to sunlight and sunlamps. You are advised to use a sunscreen and wear protective clothing while going out to prevent sunburn.
Yes, Hydroquinone+mometasone+tretinoin may cause skin irritation, burning sensation or itching at the site of application in rare cases. However, if the irritation persists or worsens, stop using Hydroquinone+mometasone+tretinoin and consult a doctor.
You are advised to use moisturizer in the morning every day to restore fat barrier of the skin that protects the skin from damage. Hydroquinone+mometasone+tretinoin may make the skin more sensitive to extreme weather conditions such as cold and wind. Therefore, wear protective clothing and use moisturizer as required. However, please consult a doctor before using moisturizing lotions or any other products with Hydroquinone+mometasone+tretinoin.
No, Hydroquinone+mometasone+tretinoin is not used to treat diaper rash as using Hydroquinone+mometasone+tretinoin under child’s nappy enables Hydroquinone+mometasone+tretinoin to pass through the skin easily and cause adverse effects. However, please consult a doctor before using Hydroquinone+mometasone+tretinoin in children.
You are not recommended to use Hydroquinone+mometasone+tretinoin with benzoyl peroxide, hydrogen peroxide or any other peroxide products as it may cause staining of the skin which can be usually removed with soap and water. However, please consult a doctor before using other medicines with Hydroquinone+mometasone+tretinoin.
You are recommended to use Hydroquinone+mometasone+tretinoin for as long as your doctor has prescribed it. However, avoid using Hydroquinone+mometasone+tretinoin for more than 6 to 8 weeks without doctor’s advice.
Hormonal contraceptives like oral/vaginal birth control pills, injections, implants, skin patches, and vaginal rings can cause melasma to get worse. So, it is advisable to ask your doctor about using non-hormonal birth control (condom, diaphragm with spermicide) instead.
