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Reviewed By Sunny S , MBBS
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Composition

ESTRADIOL-2MG

Manufacturer/Marketer

Eurozen Healthcare

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Menobet-2 Tablet

Menobet-2 Tablet contains a semi-synthetic female hormone Estradiol, indicated for hormonal replacement therapy for treating hypoestrogenism (estrogen deficiency), osteoporosis (thinning of bones) and symptoms associated with menopause (itching, dryness in the vagina, hot flashes). In addition to this, it also helps in preventing osteoporosis. Menobet-2 Tablet is prescribed when the body is not producing a sufficient amount of natural estrogen.

Menobet-2 Tablet contains estradiol which regulates the menstrual cycle and ovulation. Menobet-2 Tablet works by replacing the normal hormone estrogen functions in the body and treats symptoms associated with menopause. 

You are advised to take Menobet-2 Tablet for as long as your doctor has prescribed it for you, depending upon your medical condition. You may experience headache, bloating, hair loss, nausea, breast pain, weight gain, and irregular vaginal bleeding in some cases. Most of these side effects of Menobet-2 Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Inform your doctor if you have any history of vaginal bleeding, breast cancer, or blood clot in the legs or lungs. If you are pregnant or breastfeeding, please do not take Menobet-2 Tablet . While taking Menobet-2 Tablet , your doctor may advise regular tests to monitor its working. Grapefruit juice and St.John’s wort (a natural remedy for depression) should not be taken along with Menobet-2 Tablet . 

Uses of Menobet-2 Tablet

Hormonal replacement therapy, Hypoestrogenism (estrogen deficiency), Osteoporosis (thinning of bones), Symptoms associated with menopause (itching, dryness in vagina, hot flushes)

Directions for Use

Swallow Menobet-2 Tablet as a whole with a glass of water, do not chew or crush it.

Medicinal Benefits

Menobet-2 Tablet contains a synthetic female hormone that regulates ovulation and menstruation in women. Menobet-2 Tablet is given as a hormone replacement therapy for estrogen. It is also used in the treatment to relieve symptoms of menopause, such as mood swings, reduced sex drive, hot flashes, night sweats and vaginal dryness. 

Storage

Store in a cool and dry place away from sunlight

Side Effects of Menobet-2 Tablet

  • Headache
  • Bloating
  • Hair loss
  • Nausea
  • Weight gain
  • Breast pain
  • Irregular vaginal bleeding

Drug Warnings

Do not take Menobet-2 Tablet if you are allergic to any of its ingredients. Inform your doctor if you have breast cancer, vaginal bleeding, blood clot in the leg (deep venous thrombosis), lungs (pulmonary embolism), vein (thrombosis), cancer of the endometrium (womb lining), any blood clotting disorder, recently had a heart attack, liver or kidney disease, porphyria (a group of liver disease), high blood pressure, if you are pregnant or breastfeeding. Avoid smoking as it greatly increases the risk of blood clots, stroke, and heart attack while taking Menobet-2 Tablet . Grapefruit juice and St. John’s wort (a natural remedy for depression) should not be taken along with Menobet-2 Tablet . 

Drug-Drug Interactions

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EstradiolBivalirudin
Critical
EstradiolClindamycin
Severe

Drug-Drug Interactions

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EstradiolBivalirudin
Critical
How does the drug interact with Menobet-2 Tablet:
When Etodolac is taken with Bivalirudin, the risk or severity of bleeding and haemorrhage increases.

How to manage the interaction:
Taking Bivalirudin with Menobet-2 Tablet can cause an interaction, consult a doctor before taking it. Do not discontinue any medications without a doctor's advice.
EstradiolClindamycin
Severe
How does the drug interact with Menobet-2 Tablet:
When taken in combination, clindamycin can lower the amount or action of Menobet-2 Tablet.

How to manage the interaction:
Co-administration of Menobet-2 Tablet with Clindamycin can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without a doctor's advice.
EstradiolPomalidomide
Severe
How does the drug interact with Menobet-2 Tablet:
Co-administration of Menobet-2 Tablet and Pomalidomide can increase the risk of serious blood clots.

How to manage the interaction:
There may be a possibility of interaction between Menobet-2 Tablet and Pomalidomide, but it can be taken if prescribed by a doctor. However, if you experience symptoms like chest pain, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness, or swelling in an arm or leg, or numbness or weakness on one side of the body, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
EstradiolExemestane
Severe
How does the drug interact with Menobet-2 Tablet:
Using Menobet-2 Tablet with Exemestane may interfere with Exemestane's activity and make it less effective in treating the condition.

How to manage the interaction:
Although there is a possible interaction between Exemestane and Menobet-2 Tablet, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
EstradiolTranexamic acid
Severe
How does the drug interact with Menobet-2 Tablet:
Co-administration of Menobet-2 Tablet with Tranexamic acid can increase the risk of blood clots.

How to manage the interaction:
Taking Menobet-2 Tablet with Tranexamic acid can lead to an interaction; however, it can be taken only if a doctor has advised it. If you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, and numbness or weakness on one side of the body contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
EstradiolAnastrozole
Severe
How does the drug interact with Menobet-2 Tablet:
Menobet-2 Tablet may interfere with anastrozole's function and make it less effective in treating your condition.

How to manage the interaction:
Co-administration of Anastrozole with Menobet-2 Tablet can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without a doctor's advice.
EstradiolLetrozole
Severe
How does the drug interact with Menobet-2 Tablet:
Letrozole may have a negative effect when used with Menobet-2 Tablet, making it less effective in treating your disease.

How to manage the interaction:
Although taking Letrozole and Menobet-2 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
EstradiolCarfilzomib
Severe
How does the drug interact with Menobet-2 Tablet:
Carfilzomib can cause serious blood clots and taking it alongside Menobet-2 Tablet may enhance the risk.

How to manage the interaction:
Co-administration of Menobet-2 Tablet with Carfilzomib can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience symptoms like chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness, or swelling in an arm or leg, or numbness or weakness on one side of the body, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
EstradiolDantrolene
Severe
How does the drug interact with Menobet-2 Tablet:
The usage of Menobet-2 Tablet with dantrolene might have significant adverse effects on your liver.

How to manage the interaction:
Taking Menobet-2 Tablet with Dantrolene together can result in an interaction, but it can be taken if a doctor has advised it. However, if you have a fever, chills, joint pain or swelling, severe fatigue or weakness, unusual bleeding or bruising, skin rash or itching, lack of appetite, nausea, vomiting, or yellowing of the skin or whites of your eyes, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
EstradiolLenalidomide
Severe
How does the drug interact with Menobet-2 Tablet:
Coadministration of Menobet-2 Tablet and Lenalidomide can increase the risk of blood clots.

How to manage the interaction:
Although there is an interaction between lenalidomide and Menobet-2 Tablet, it can be taken if your doctor has advised it. However, if you experience chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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ESTRADIOL-2MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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ESTRADIOL-2MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
The rate of absorption of oral estrogens may be increased by coadministration with grapefruit juice. Avoid or restrict the consumption of grapefruit juice while taking Menobet-2 Tablet.

Diet & Lifestyle Advise

  • Do regular exercise and physical activity to minimize hot flashes and improve sleep. Besides this, weight-bearing exercises can help in making your bone strong. Aerobics, yoga, and activities like tai chi may help relax the body and mind.
  • Try to wear loose clothes before going to bed and sleep in a cool, well-ventilated room. Doing this can prevent symptoms of hot flashes and night sweats. Take minimum sleep of 8 hours. 
  • Avoid or limit intake of caffeine-containing beverages, alcohol, and spicy food, as these are known triggering agents for hot flushes.
  • Try to be stress-free to improve your mood swings due to hormonal fluctuations. 
  • Quitting smoking will help reduce hot flashes and your risk of developing chronic conditions like heart disease, stroke, and cancer.

Habit Forming

No

Therapeutic Class

HORMONES

Menobet-2 Tablet Substitute

Substitutes safety advice
  • Estrabet 2 Tablet 28's

    by AYUR

    21.31per tablet
  • Progynova 2 mg Tablet 28's

    by Others

    20.25per tablet
  • Endofert H 2 Tablet 28's

    by Others

    17.28per tablet
  • Evatone-2 Tablet 10's

    by Others

    14.04per tablet
  • Evadiol Tablet 28's

    by Others

    12.30per tablet

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Menobet-2 Tablet works by replacing the normal hormone estrogen functions in the body and treats symptoms associated with menopause.

Do not use Menobet-2 Tablet if you are allergic to peanuts, have unusual vaginal bleeding, have/had any cancer (breast or uterus cancer), or undergoing any other estrogen treatment. Tell your doctor if you had a heart attack, stroke, blood clot, or liver problems, if you are pregnant, breastfeeding, or planning to get pregnant.

No, Menobet-2 Tablet should not be taken if you are undergoing surgery. You should inform your doctor, and he might ask you to stop hormone replacement therapy about 4 to 6 weeks before surgery to reduce the risk of blood clots.

Menobet-2 Tablet may cause either weight gain or weight loss. It is a common side effect of Menobet-2 Tablet . Regular exercise and eating a healthy diet can help prevent weight gain.

Drug-Drug Interactions Checker List

  • CARBAMAZEPINE
  • PHENYTOIN
  • GRISEOFULVIN
  • RIFAMPICIN
  • RITONAVIR
  • NELFINAVIR
  • EFAVIRENZ
  • BOSENTAN
  • ASPIRIN

Disease/Condition Glossary

Hypoestrogenism: It refers to the lowered secretion of the natural female sex hormone known as estrogen. It is an umbrella term used for estrogen deficiency in various conditions. Its abnormalities may lead to infertility, bone loss, and lipid abnormalities.

Osteoporosis: Osteoporosis means the bone has become porous. It is a disease in which too much bone is lost, and the body makes relatively little bone. As a result, bones become weak and can break easily if you fall.

Hormone replacement therapy (HRT): It is a treatment to relieve symptoms of menopause. It replaces hormones that are at a lower level as you approach menopause.

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