Mesacol Enema 60 ml belongs to a class of anti-inflammatory drugs used to treat ulcerative colitis and ulcerative proctitis. Ulcerative colitis is a chronic inflammatory bowel disease that causes inflammation of the large intestine lining (colon). It produces ulcers on the colon's lining, which may cause bleeding and discharge of pus and mucus. Ulcerative proctitis is a condition in which ulcerative colitis solely affects the rear channel (rectum).

Mesacol Enema 60 ml contains Mesalamine, which works by preventing the synthesis of chemical messengers such as prostaglandins in the intestines that produce inflammation (swelling). This lowers ulceration, bleeding, and stomach pain while preventing future illness flare-ups.

Use Mesacol Enema 60 ml as directed by your physician. Sometimes, you may experience diarrhoea, stomach pain, headache or nausea. Most of these side effects of Mesacol Enema 60 ml do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Before taking the Mesacol Enema 60 ml, let your doctor know about all your medical conditions, sensitivities, and all medications you are using. And also, inform your doctor if you have severe kidney or liver failure or blood abnormalities like porphyria. Mesacol Enema 60 ml should not be used in pregnant and breastfeeding mothers unless necessary. So, inform your doctor if you are pregnant or breastfeeding. Your doctor will weigh the benefits and potential risks before prescribing Mesacol Enema 60 ml.

Mesacol Enema 60 ml contains Mesalamine, an anti-inflammatory drug used to treat ulcerative colitis and ulcerative proctitis. It can also help treat other inflammatory bowel disease types, such as Crohn’s disease. It works by inhibiting the production of certain chemical substances, such as prostaglandins, that cause pain and swelling. Thereby helping reduce inflammation (redness and swelling) in the intestines and providing relief from symptoms such as stomach pain or bleeding. Also, Mesacol Enema 60 ml may prevent further episodes of ulcerative colitis. It is especially useful when ulcerative colitis symptoms affect the rectum.

• Feeling sick (Nausea)
• Being sick (Vomiting)
• Diarrhoea
• Stomach pain, indigestion
• Headaches
• Muscle aches

Before taking the Mesacol Enema 60 ml, let your doctor know about all your medical conditions, sensitivities, and all medications you are using. Do not use Mesacol Enema 60 ml if you are pregnant, planning to become pregnant, or breastfeeding without first consulting the doctor. Mesacol Enema 60 ml is recommended not to be used in populations with severe renal or hepatic impairment, so inform your doctor if you have severe renal or hepatic impairment. Use Mesacol Enema 60 ml in dose and duration as advised by a doctor only. Do not swallow Mesacol Enema 60 ml. In case of accidental swallowing, drink plenty of water and consult a doctor immediately.

Drug-Drug Interactions: Mesacol Enema 60 ml may interact with non-steroidal anti-inflammatory drugs (e.g. aspirin, ibuprofen), immunosuppressant medications (e.g. azathioprine), anticoagulants (e.g. warfarin) and laxatives (e.g. lactulose).

Drug-Food Interactions: No interactions found.

Drug-Disease Interactions: Mesacol Enema 60 ml may interact with disease conditions, including Severe impairment of hepatic or renal function and a rare blood condition called porphyria.

• ASPIRIN
• IBUPROFEN
• AZATHIOPRINE
• WARFARIN
• LACTULOSE

• Maintain a low-fat diet and eat foods rich in vitamin C, such as bell peppers, spinach, parsley and berries, which help heal faster.
• Opt for food and drinks high in Omega 3 fatty acids to relieve pain, swelling, and inflammation. Omega 3 rich acid-enriched foods include flaxseeds, walnut, soybean oil, salmon, and tuna if you prefer non-veg.
• Eat more fibre-rich foods such as fruits and vegetables.
• Eat smaller meals all day.
• Drink small amounts of water throughout the day.
• If you are intolerant to lactose, lower your intake of milk.
• Avoid foods high in sugar, fat, and processed foods, as these, may cause inflammation.
• Try to avoid alcohol as it can affect your stomach and intestine and also limits the absorption of the important nutrients required by your body.

Ulcerative colitis: Ulcerative colitis is a type of chronic inflammatory bowel disease that causes inflammation of the lining of the large intestine (colon) and produces ulcers on the lining of the colon, which may cause bleeding and discharge of pus and mucus. The common symptoms include bloody stools, stomach pain, rectal pain, diarrhoea, and fever or weight loss. Additionally, it may cause other problems such as joint pain or swelling, mouth sores, skin problems, decreased appetite or nausea. The factors involved in causing ulcerative colitis include immune disorders and environmental factors like viruses, bacteria or antigens, which may trigger the immune system and genes inherited from the parent. 

Ulcerative proctitis: Ulcerative proctitis is a condition in which ulcerative colitis solely affects the rear channel (rectum). Proctitis is a painful and unpleasant condition. You may have a persistent urge to urinate. Medications and lifestyle changes are typically used to address the illness.

Crohn's disease: Crohn's disease is a chronic inflammatory disorder that affects the digestive tract. It is a kind of inflammatory bowel disease (IBD). Diarrhoea, stomach aches and cramps, blood in your poo, exhaustion (fatigue), and weight loss are the most common symptoms.