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Manufacturer/Marketer :

Ajanta Pharma Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Met XL AM 25/5 Tablet

Met XL AM 25/5 Tablet belongs to the group of antihypertensive agents used to treat high blood pressure/hypertension and angina pectoris. High blood pressure is a condition in which the blood exerts increased pressure on the walls of blood vessels. Angina is basically a pain in the heart and chest. 

Met XL AM 25/5 Tablet contains Metoprolol succinate and Amlodipine. Metoprolol succinate works by slowing down the heart rate, thereby making it more efficient at pumping blood throughout the body. Amlodipine relaxes the blood vessels, thereby improving blood flow. Together, Met XL AM 25/5 Tablet helps treat high blood pressure.

Take Met XL AM 25/5 Tablet as prescribed. In some cases, Met XL AM 25/5 Tablet may cause certain common side effects such as tiredness, dizziness, headache, ankle swelling and slow heart rate. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist or worsen.

It is advisable to inform the doctor if you are allergic to any of its components. Consult your doctor if you are pregnant, planning to get pregnant, or breastfeeding. Keep your doctor informed in case you are due to undergo any surgery or dental procedure. Avoid consuming alcohol with Met XL AM 25/5 Tablet as there may be an interaction. Met XL AM 25/5 Tablet  may cause dizziness, therefore, drive only if you are alert.

Uses of Met XL AM 25/5 Tablet

Hypertension, Angina pectoris

Directions for Use

Take Met XL AM 25/5 Tablet with or without food as directed by the physician. Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Met XL AM 25/5 Tablet is a combination antihypertensive medication containing Metoprolol succinate and Amlodipine. It is used primarily to treat hypertension and to relax the blood vessels for seamless flow of blood. Metoprolol succinate is a beta-blocker that eases the symptoms of hypertension by blocking catecholamines that lead to increased pressure and heart rate. Amlodipine is a calcium channel blocker that decreases blood pressure by preventing the influx of calcium ions into cells and by enlarging and relaxing arteries. In addition, Met XL AM 25/5 Tablet also reduces the oxygen demands of the heart, relaxing the heart and blood vessels and requiring the heart to do less work.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Met XL AM 25/5 Tablet

  • Tiredness
  • Dizziness
  • Headache
  • Ankle swelling
  • Slow heart rate
  • Stomach pain
  • Shortness of breath
  • Rash or itch
  • Cold hands and feet

Drug Warnings

Met XL AM 25/5 Tablet should not be used in case of any known allergy to either of the components. Met XL AM 25/5 Tablet should be used with caution in case of high risk or previous history of any arterial or thrombotic disorders, shock, cardiovascular health disorders, diabetes, heart failure, or any disease-causing psoriasis. Please inform your doctor in case of any history of an overactive thyroid, asthma, phaeochromocytoma (high BP due to a tumour in the adrenal glands), myasthenia gravis (neuromuscular disorder), COPD, heart block, liver disease or renal disease. Consult your doctor before using Met XL AM 25/5 Tablet during pregnancy or breastfeeding. Keep your doctor informed in case you are waiting to undergo any surgery or dental procedure. Met XL AM 25/5 Tablet may interact with alcohol, please consult your doctor before use. Met XL AM 25/5 Tablet may cause dizziness, so drive or operate heavy machinery only if you are alert. 

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
AmlodipineItraconazole
Severe

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
How does the drug interact with Met XL AM 25/5 Tablet:
Using Met XL AM 25/5 Tablet together with dantrolene may increase the risk of hyperkalemia (high blood potassium).

How to manage the interaction:
Taking Met XL AM 25/5 Tablet with Dantrolene can cause an interaction, consult a doctor before taking it. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
AmlodipineItraconazole
Severe
How does the drug interact with Met XL AM 25/5 Tablet:
Coadministration of Met XL AM 25/5 Tablet with itraconazole may significantly raise the blood levels and effects of Met XL AM 25/5 Tablet.

How to manage the interaction:
Met XL AM 25/5 Tablet and itraconazole may interact, but if prescribed by a doctor, they can be used together. Consult a doctor if you develop chest discomfort, trouble breathing, dizziness or fainting, swelling of the hands, ankles, or feet, or any other of these symptoms. Without consulting a doctor, never stop taking any medication.
AmlodipinePhenobarbital
Severe
How does the drug interact with Met XL AM 25/5 Tablet:
Using phenobarbital and Met XL AM 25/5 Tablet may drastically lower Met XL AM 25/5 Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although co-administration of phenobarbital with Met XL AM 25/5 Tablet can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipinePhenytoin
Severe
How does the drug interact with Met XL AM 25/5 Tablet:
Using Met XL AM 25/5 Tablet and phenytoin together may drastically lower Met XL AM 25/5 Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although Met XL AM 25/5 Tablet with phenytoin can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipineRifabutin
Severe
How does the drug interact with Met XL AM 25/5 Tablet:
Using Met XL AM 25/5 Tablet and rifabutin together may lower Met XL AM 25/5 Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although there is an interaction between Met XL AM 25/5 Tablet with rifabutin, but it can be taken if a doctor has advised it. Consult the doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
AmlodipineSirolimus
Severe
How does the drug interact with Met XL AM 25/5 Tablet:
Co-administration of Met XL AM 25/5 Tablet can make Sirolimus may increase the risk of angioedema (a condition associated with swelling of the face, eyes, lips, tongue, throat, and occasionally also the hands and feet).

How to manage the interaction:
There may be a possibility of interaction between Met XL AM 25/5 Tablet and Sirolimus, but it can be taken if prescribed by a doctor. However, consult the doctor if you notice any swelling of the face, eyes, lips, tongue, throat, hands and feet or have trouble breathing or swallowing. Do not stop using any medications without a doctor's advice.
AmlodipineEnzalutamide
Severe
How does the drug interact with Met XL AM 25/5 Tablet:
Using a combination of Met XL AM 25/5 Tablet and enzalutamide may drastically lower Met XL AM 25/5 Tablet blood levels, making the medicine less effective.

How to manage the interaction:
Taking Met XL AM 25/5 Tablet with enzalutamide can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipinePrimidone
Severe
How does the drug interact with Met XL AM 25/5 Tablet:
Using Met XL AM 25/5 Tablet and primidone together may lower Met XL AM 25/5 Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although co-administration of Met XL AM 25/5 Tablet with primidone can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipineIdelalisib
Severe
How does the drug interact with Met XL AM 25/5 Tablet:
Coadministration of Met XL AM 25/5 Tablet and Idelalisib may raise Met XL AM 25/5 Tablet levels in the blood this may lead to serious side effects (irregular heart rhythm, fluid retention, swelling, heart failure, and abnormally low blood pressure).

How to manage the interaction:
Although taking Met XL AM 25/5 Tablet with idelalisib can result in an interaction, it can be taken if a doctor has advised it. However, if you experience dizziness or fainting, sudden, unexplained weight gain, swelling of the hands, ankles, or feet, chest discomfort, or trouble breathing while taking these drugs, consult the doctor. Use caution while getting up from a sitting or sleeping position and avoid driving or using dangerous machinery. Do not stop using any medications without a doctor's advice.
AmlodipineSimvastatin
Severe
How does the drug interact with Met XL AM 25/5 Tablet:
Taking simvastatin with Met XL AM 25/5 Tablet may result in considerably higher blood levels of simvastatin and may increase the risk of side effects (liver damage and rhabdomyolysis - an uncommon but serious illness characterized by the breakdown of skeletal muscle tissue).

How to manage the interaction:
Although taking Met XL AM 25/5 Tablet with simvastatin can result in an interaction, it can be taken if a doctor has advised it. If you have unexplained muscular pain, soreness, or weakness while using simvastatin, especially if these symptoms are accompanied by fever or dark-colored urine, consult the doctor immediately. However, if you develop a fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, and/or yellowing of the skin or eyes, consult the doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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AMLODIPINE-5MG+METOPROLOL SUCCINATE-25MGFruit juices, Fruits
Moderate

Drug-Food Interactions

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AMLODIPINE-5MG+METOPROLOL SUCCINATE-25MGFruit juices, Fruits
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Taking Amlodipine and Metoprolol with grapefruit and grapefruit juice significantly increases the metabolism of Amlodipine. Avoid taking Amlodipine and Metoprolol with grapefruit and grapefruit juice.

Diet & Lifestyle Advise

  • Limit the intake of salt in your diet.
  • Cut back on foods that are high in fat and cholesterol.
  • Eat more fruits, vegetables and whole-grain foods.
  • Avoid taking Met XL AM 25/5 Tablet with grapefruit juice as there may be an interaction.
  • Avoid tobacco use. Inform your doctor in case of marijuana use.
  • Dress warmly, as Met XL AM 25/5 Tablet may cause cold extremities.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Met XL AM 25/5 Tablet Substitute

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Met XL AM 25/5 Tablet works by reducing the workload on the heart and vessels and relaxing the vessels to ensure a fluid flow of blood, easing any hypertension and effects of the same.

Do not stop taking Met XL AM 25/5 Tablet without consulting your doctor as it may lead to a rise in blood pressure. To treat your condition effectually, continue taking Met XL AM 25/5 Tablet for as long as your doctor has prescribed it to you. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Met XL AM 25/5 Tablet .

Hyponatremia (a term for low blood sodium levels) often results in lowering blood pressure and falls. One of the not so common side-effects of Met XL AM 25/5 Tablet is dizziness and lowered BP. Hence, it is best to consult your physician before taking Met XL AM 25/5 Tablet if you suffer from this condition.

Light-headedness could be a side-effect of Met XL AM 25/5 Tablet . It occurs due to low blood pressure leading to dizziness on standing. If you experience this, do not try to stand up suddenly or start walking, instead lie down and get up slowly only when you feel better. People taking Met XL AM 25/5 Tablet are advised to regularly monitor their blood pressure levels to avoid unpleasant events.

Met XL AM 25/5 Tablet is not known to affect fertility. However, not enough literature and studies exist to ascertain the effect of Met XL AM 25/5 Tablet on fertility. Please consult your doctor in case of any concerns.

Drug-Drug Interactions Checker List

  • QUINIDINE
  • PROPAFENONE
  • FLUOXETINE
  • PAROXETINE
  • DILTIAZEM
  • CLONIDINE
  • VERAPAMIL
  • ERYTHROMYCIN
  • KETOCONAZOLE
  • ITRACONAZOLE
  • RITONAVIR
  • DIGITALIS

Special Advise

  • In case you miss a dose of Met XL AM 25/5 Tablet , take it as soon as possible. However, if it is too close to the next dose, revert to the original schedule. Do not ever take a double dose.
  • If you accidentally take an extra dose of Met XL AM 25/5 Tablet , please inform your doctor immediately. Some of the common symptoms of an overdose can be low blood pressure, slow pulse rate, shortness of breath, low blood sugar, dizziness, feeling sick and blue discolouration of the skin.
  • Do not discontinue taking Met XL AM 25/5 Tablet abruptly or without the advice of the physician.
  • Please know that your doctor may order blood tests to check your tolerance and need of Met XL AM 25/5 Tablet .
  • Met XL AM 25/5 Tablet should be used with caution in case of those over 80 or under 40 years of age.

Disease/Condition Glossary

Hypertension: Hypertension is defined as a condition in which the blood pressure remains high persistently. Normal BP is marked at 120/80 mmHg. Hypertension is defined as consistent blood pressure over 140/90 mm Hg. Hypertension expresses itself in various symptoms such as fatigue, irregular pulse rate, headache, dizziness, chest pain etc.

Angina Pectoris: Discomfort in the chest or the heart is referred to as angina. It occurs when the workload on the heart increases and when the heart does not get as much blood as it needs. Symptoms of angina include chest tightness, pressure and heaviness in the chest.

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