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Methergin Injection 1 ml

Methergin Injection 1 ml

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Prescription drug
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Manufacturer/Marketer

Novartis India Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About Methergin Injection 1 ml

Methergin Injection 1 ml belongs to the class of medication called 'ergot alkaloids' or 'uterotonic' primarily used to prevent and stop heavy bleeding (postpartum-third stage of labour bleeding) after childbirth or after a miscarriage in cesarean section. Besides this, it is also used to improve uterine contraction (antepartum) and produce uterine contraction during the third stage of labor (postpartum). Postpartum haemorrhage is heavy bleeding (more than normal) after the birth of the baby.

Methergin Injection 1 ml contains a semi-synthetic ergot alkaloid 'Methylergometrine', that stimulates uterine muscles and increases the uterus' contractions, thus reducing blood loss. It also increases the effects of a natural substance called prostaglandins (PGs), increasing contractions and producing labour. As a result, these increased uterine contractions help in the child's delivery and substantially reduce excessive uterine bleeding. 

Methergin Injection 1 ml will be administered by a healthcare professional. Do not self-administer. The most common side effects of Methergin Injection 1 ml are nausea, vomiting, stomach pain, and mild headache in some cases. Most of these side effects of Methergin Injection 1 ml do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

If you ever had surgery on the uterus, cesarean, or premature labour, please inform your doctor to avoid any complications. If you have been given prostaglandins, then do not take Methergin Injection 1 ml; if both medicines are taken together, it can increase the contractions. Methergin Injection 1 ml should not be used for a prolonged time if the contractions do not increase or have severe pre-eclamptic toxemia (high blood pressure, protein in the urine, and swelling), blood or heart circulation problem. 

Uses of Methergin Injection 1 ml

Postpartum haemorrhage

Medicinal Benefits

Methergin Injection 1 ml contains a semi-synthetic ergot alkaloid 'Methylergometrine' primarily used to stop heavy bleeding postpartum, i.e. third stage of labour bleeding after childbirth or after a miscarriage in cesarean section. Additionally, it plays a significant role in birth by increasing uterus contractions and inducing labour in pregnant women. Methergin Injection 1 ml works by stimulating uterine muscles and expanding the uterus' contractions, thus reducing blood loss. It also increases the effects of a natural substance called prostaglandins (PGs), increases the contraction,s and hence induces labour. As a result, these increased uterine contractions help deliver the child and substantially reduce excessive uterine bleeding.

Directions for Use

Methergin Injection 1 ml will be administered by a healthcare professional under strict medical supervision. Do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Methergin Injection 1 ml

  • Nausea
  • Vomiting
  • Headache
  • Stomach pain

Drug Warnings

Do not take Methergin Injection 1 ml if you are allergic to Methergin Injection 1 ml or any of its ingredients. Increasing the dose of Methergin Injection 1 ml can be harmful if your womb already has too strong contractions, any obstructions in the pathway that might prevent the delivery or if the baby is not receiving a sufficient oxygen supply. Also, the use of Methergin Injection 1 ml is not advisable if the baby is wrongly positioned in the birth canal, the baby’s head is too large to fit through the pelvis, the placenta lies near the neck of the womb, the placenta separates from the womb before birth, the womb is over-extended and likely to tear (in case you are carrying more than one baby). If you have been given prostaglandins, do not use Methergin Injection 1 ml within 6 hours as both medications, if taken together, can increase the contractions. Methergin Injection 1 ml should not be used for a prolonged time if the contractions do not increase or if you have severe pre-eclamptic toxaemia (high blood pressure, protein in the urine, and swelling) or blood or heart circulation problems.

Drug Interactions

Drug-Drug Interaction: Methergin Injection 1 ml may interact with anaesthetics (sevoflurane, halothane, cyclopropane, desflurane), other medicines used to start labour (prostaglandins), anti-diuretic hormone (vasopressin), a neurotransmitter (dopamine), anti-sickness medicine (ondansetron), sympathomimetic agents (epinephrine).

Drug-Food Interaction: Grapefruit juice intake should be avoided with Methergin Injection 1 ml as it may interact with Methergin Injection 1 ml to produce unpleasant side effects.

Drug-Disease Interaction: Methergin Injection 1 ml should not be given to patients with previous cesarean section, hypertension (high blood pressure), heart problem, cervical cancer, herpes infection, kidney problem, if you are more than 40 weeks pregnant or are more than 35 years age, the pelvis is too small for normal delivery.

Drug-Drug Interactions Checker List

  • PROSTAGLANDINS
  • DESFLURANE
  • CYCLOPROPANE
  • DOPAMINE
  • EPINEPHRINE
  • HALOTHANE
  • ONDANSETRON
  • VASOPRESSIN
  • SEVOFLURANE

Habit Forming

No

Diet & Lifestyle Advise

  • Long walks can help to relieve stress, keep your body strong, and help in easy delivery.
  • Please take a little bit of Castrol oil as it is known to stimulate prostaglandin, which ripens the cervix and get labor started.
  • Some food like dates, raspberry tea leaves are known to ripen the cervix and get labor started.
  • Acupressure also stimulates labor and helps in delivery.

Special Advise

  • Methergin Injection 1 ml when given for induction of labor, stimulation of labor and prevention of vaginal bleeding after delivery of the baby especially after caesarean surgery. It must be administered only by the intravenous (IV) or intramuscular (IM) route under medical supervision in a hospital setting only. 

Disease/Condition Glossary

Postpartum haemorrhage: It is a serious but rare condition which causes excessive vaginal bleeding within one day after giving birth to the child. It happens mostly in cases of cesarean birth. When a baby is delivered, the uterus of the body contracts and forces out the placenta. After the placenta's delivery, these contractions put pressure on the bleeding vessels at the place where the placenta was attached, resulting in vaginal bleeding. It is normal to lose some amount of blood after delivery, but if a woman is losing more blood than normal, it can be dangerous. 

Country of origin

India

Manufacturer/Marketer address

Sandoz House, Shiv Sagar Estate, Worli Mumbai -400 018, India
Other Info - MET0066

FAQs

Methergin Injection 1 ml works by stimulating uterine muscles and increasing the uterus' contractions, thus reducing blood loss. It also increases the effects of a natural substance called prostaglandins (PGs), and increases the contraction, thereby inducing labour pain in pregnant women. As a result, these increased uterine contractions help in the child's delivery and substantially reduce excessive uterine bleeding.
If you have a previous premature delivery or a cesarian section, or cervical surgery, please inform your doctor before starting Methergin Injection 1 ml. Also, mention a detailed medical history to your doctor to avoid any complications.
The most common side effects of Methergin Injection 1 ml include nausea, vomiting, stomach pain, mild headache. You might also feel increased uterine contractions for some time, but these are manageable under medical supervision.
It is suggested to avoid grapefruit and grapefruit juice while taking Methergin Injection 1 ml as it can worsen the side effects of Methergin Injection 1 ml.
It is advised to tell your doctor if you are using antifungal medicine (Fluconazole) or other medicine, including prescription and over-the-counter medicines, vitamins, and herbal products, as taking Methergin Injection 1 ml with some medications may cause serious side effects.

Disclaimer

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Keep Refrigerated. Do not freeze.Prepaid payment required.

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Alcohol

Unsafe

It is not known if alcohol affects Methergin Injection 1 ml. Consult your doctor.

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Pregnancy

Unsafe

Methergin Injection 1 ml is not recommended for use during pregnancy.

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Breast Feeding

Unsafe

It is advised to avoid breastfeeding for at least 12 hours after taking Methergin Injection 1 ml as this medicine may pass into breast milk and can harm a nursing baby.

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Driving

Unsafe

Avoid driving and operating machinery.

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Liver

Safe if prescribed

Methergin Injection 1 ml is not known to show any interaction in liver disease.

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Kidney

Caution

Methergin Injection 1 ml to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose will be adjusted by your doctor.

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Children

Unsafe

Methergin Injection 1 ml is not recommended for children below the age of 18 years. The safety and effectiveness of Methergin Injection 1 ml have not been established in children.

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