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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sunny S , MBBS
Non returnable*
COD available

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Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About Migranil Tablet 10's

Migranil Tablet 10's belongs to the class of medications called 'antimigraine agents' used to prevent migraine symptoms like intense throbbing in one area, headache, nausea and vomiting. Hormonal changes, stress, lack or excess of sleep, bright lights, loud sounds, certain foods and drinks can trigger migraine headaches. 
 
Migranil Tablet 10's contains Ergotamine (alkaloid), Caffeine (methylxanthine), Paracetamol (mild analgesic) and Belladonna (alkaloid). Ergotamine works by narrowing the blood vessels in the brain and affects the blood flow patterns associated with headaches. Caffeine enhances the vasoconstrictive effect (narrowing of blood vessels). Belladonna works by blocking the chemicals of the nervous system. Paracetamol blocks the release of prostaglandins that cause pain and fever. Together, Migranil Tablet 10's helps treat signs and symptoms of migraine.
 
You are advised to take Migranil Tablet 10's for as long as your doctor has prescribed it for you depending on your medical condition. You may experience certain common side-effects such as stomach pain, dizziness, dry mouth and diarrhoea in some cases. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.
 
Migranil Tablet 10's contains paracetamol, do not take other medicines containing paracetamol along with Migranil Tablet 10's unless prescribed. Do not take Migranil Tablet 10's if you are pregnant or breastfeeding. Migranil Tablet 10's may cause dizziness, so drive with caution. Migranil Tablet 10's should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol with Migranil Tablet 10's as it could lead to increased dizziness. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Uses of Migranil Tablet 10's

Migraine

Directions for Use

Swallow Migranil Tablet 10's as a whole with a glass of water, do not chew or break it.

Medicinal Benefits

Migranil Tablet 10's is a combination of four drugs, namely: Ergotamine, caffeine, belladonna and paracetamol. Migranil Tablet 10's is indicated to treat and prevent migraine. Ergotamine is an ergot alkaloid that works by narrowing the blood vessels in the brain and also affects the blood flow patterns associated with headache. Caffeine is a methylxanthine which enhances the vasoconstrictive effect (narrowing of blood vessels). Belladonna works by blocking the chemicals of the nervous system. Paracetamol is an analgesic which blocks the release of prostaglandins that cause pain. Together, Migranil Tablet 10's helps in treating migraine.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Migranil Tablet 10's

  • Stomach pain
  • Dizziness
  • Dry mouth
  • Diarrhoea
  • Constipation
  • Tachycardia (increased heart rate)
  • Blurred vision

Drug Warnings

Do not take Migranil Tablet 10's if you are allergic to any of its contents, if you have/had heart problems, blood circulation problems, or if you are taking antibiotics, anti-fungal, anti-HIV or other anti-migraine medicines. Migranil Tablet 10's contains paracetamol, do not take other medicines containing paracetamol along with Migranil Tablet 10's unless prescribed. Inform your doctor if you have high blood pressure, heart problems, high cholesterol, diabetes, asthma, liver or kidney problems. Do not take Migranil Tablet 10's if you are pregnant or breastfeeding. Migranil Tablet 10's may cause dizziness, so drive only if you are alert. Migranil Tablet 10's is not recommended for children as safety and effectiveness have not been established. Avoid consuming alcohol with Migranil Tablet 10's as it could lead to increased dizziness. Do not take any other medicines for pain relief along with Migranil Tablet 10's unless prescribed. 

Drug-Drug Interactions

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CaffeineTranylcypromine
Critical
CaffeinePhenelzine
Critical

Drug-Drug Interactions

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CaffeineTranylcypromine
Critical
How does the drug interact with Migranil Tablet:
Coadministration of tranylcypromine with Migranil Tablet can in cause severe high blood pressure.

How to manage the interaction:
Taking Migranil Tablet with Tranylcypromine is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience headache, confusion, blurred vision, problems with speech or balance, nausea, vomiting, chest pain, convulsions, and sudden numbness or weakness (especially on one side of the body). Do not discontinue any medications without consulting a doctor.
CaffeinePhenelzine
Critical
How does the drug interact with Migranil Tablet:
Taking these two together can cause your blood pressure to rise, a condition known as a hypertensive crisis.

How to manage the interaction:
Taking Migranil Tablet with Phenelzine is not recommended, please consult your doctor before taking it. They can be taken if your doctor advises it. Do not stop taking any medication without consulting your doctor.
CaffeineLinezolid
Critical
How does the drug interact with Migranil Tablet:
Taking these two together can cause your blood pressure to rise, a condition known as a hypertensive crisis.

How to manage the interaction:
Taking Migranil Tablet with Linezolid is not recommended, please consult your doctor before taking it. It can be taken if your doctor prescribes it. Do not stop taking any medication without consulting your doctor.
CaffeineIsocarboxazid
Critical
How does the drug interact with Migranil Tablet:
Taking these two together can cause your blood pressure to rise, a condition known as a hypertensive crisis.

How to manage the interaction:
Taking Migranil Tablet with Isocarboxazid is not recommended, please consult your doctor before taking it. It can be taken if your doctor prescribes it. Do not stop taking any medication without consulting your doctor.
ErgotamineSumatriptan
Critical
How does the drug interact with Migranil Tablet:
Coadministration of Migranil Tablet with Sumatriptan can reduce blood flow and increase the risk of serious side effects such as high blood pressure or heart-related disorders.

How to manage the interaction:
There may be a possibility of interaction between Sumatriptan and Migranil Tablet, but it can be taken if prescribed by a doctor. However, if you experience abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of fingers or toes, pale or cold skin, chest pain or tightness, irregular heartbeat, severe headache, shortness of breath, blurred vision, confusion, call a doctor. Do not discontinue any medication without consulting a doctor.
ErgotamineSelegiline
Critical
How does the drug interact with Migranil Tablet:
When Migranil Tablet is taken with Selegiline, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
There may be a possibility of interaction between Migranil Tablet and Selegiline, but it can be taken if prescribed by a doctor. If you notice any of these signs - like confusion, hallucination, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramps, nausea, vomiting, and diarrhea-call a doctor. Do not stop using any medications without a doctor's advice.
ErgotamineMifepristone
Critical
How does the drug interact with Migranil Tablet:
When Mifepristone is taken with Migranil Tablet, it may increase the blood levels of Migranil Tablet, which may result in side effects.

How to manage the interaction:
Taking Migranil Tablet with Mifepristone is not recommended, but it can be taken if prescribed by the doctor. Do not stop using any medications without talking to a doctor.
ErgotamineCeritinib
Critical
How does the drug interact with Migranil Tablet:
Taking Migranil Tablet with ceritinib can significantly increase the blood levels and effects of Migranil Tablet.

How to manage the interaction:
Taking Ceritinib with Migranil Tablet is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience severe abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of fingers or toes, pale or cold skin, chest pain or tightness, irregular heartbeat, severe headache, shortness of breath, blurred vision, confusion, and trouble speaking. Do not discontinue any medications without consulting a doctor.
ErgotamineRitonavir
Critical
How does the drug interact with Migranil Tablet:
Taking Migranil Tablet with ritonavir may significantly increase the blood levels and effects of Migranil Tablet.

How to manage the interaction:
Taking Migranil Tablet with Ritonavir is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of fingers or toes, pale or cold skin, chest pain or tightness, irregular heartbeat, severe headache, shortness of breath, blurred vision, confusion, and/or slurred speech, contact a doctor. Do not discontinue any medications without consulting a doctor.
ErgotamineTranylcypromine
Critical
How does the drug interact with Migranil Tablet:
Coadministration of Migranil Tablet and Tranylcypromine can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Tranylcypromine with Migranil Tablet is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a healthy diet and exercise regularly as it helps in improving overall health and boosts self-esteem.
  • Avoid bright lights, loud noise, and extreme temperatures.
  • Perform meditation and yoga. This helps in relieving stress and provides relaxation.
  • Follow a regular sleep pattern to improve the amount and quality of sleep you get.
  • Massage your scalp to ease the pain.
  • Lie down in a quiet, dark room.
  • Place a cold cloth over your forehead or neck.
  • Avoid smoking, alcohol, and caffeinated drinks. 
  • Learn what triggers your migraine and try avoiding them.
  • Stay hydrated. Drink plenty of fluids.
  • Learn relaxation skills as they help in reducing stress.

Habit Forming

No

Therapeutic Class

ANTIMIGRAINE AGENTS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • CLARITHROMYCIN
  • ERYTHROMYCIN
  • TROLEANDOMYCIN
  • ITRACONAZOLE
  • KETOCONAZOLE
  • INDINAVIR
  • NELFINAVIR
  • RITONAVIR
  • OXYMETAZOLINE
  • ACETAMINOPHEN
  • FENTANYL
  • BUTALBITAL
  • FLUOXETINE
  • DIAZEPAM
  • RANITIDINE

Disease/Condition Glossary

Migraine: Migraine is a neurological condition which is characterised by an intense, debilitating headache. Hormonal changes, stress, lack or excess of sleep, bright lights, loud sounds, certain foods and drinks can trigger migraine headaches. Migraine headache is preceded by warning symptoms one or two days prior to the headache itself. The warning symptoms include food cravings, depression, fatigue, hyperactivity, irritability and neck stiffness. Symptoms of migraine include throbbing pain in one particular area with varying intensity, nausea, vomiting, numbness or tingling sensation, difficulty speaking, sensitivity to sound and light.

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