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  1. Home
  2. Medicine

  3. Migrid Crono-500Mg Cr Tablet 10'S

Migrid Crono-500Mg Cr Tablet 10'S, Pack of 10 TabletS
Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sunny S , MBBS
Know More

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Whats That

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Composition :

SODIUM VALPROATE-333MG + VALPROIC ACID-145MG

Manufacturer/Marketer :

Searle India Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Migrid Crono-500Mg Cr Tablet

Migrid Crono-500Mg Cr Tablet belongs to a group of medicines called 'anticonvulsants' or 'anti-epileptics' primarily used to treat epilepsy/seizures/fits. Additionally, Migrid Crono-500Mg Cr Tablet is also used to treat mood disorders and migraine. Epilepsy is a sudden rush of electricity in the brain. In patients with seizures, the typical brain electrical pattern is disrupted by sudden bursts of electrical impulse that affect an individual's consciousness, movements or sensations.
­ 
Migrid Crono-500Mg Cr Tablet is a combination of two drugs, namely: Sodium valproate and Valproic acid. Migrid Crono-500Mg Cr Tablet works by decreasing the excessive and abnormal nerve activity in the brain. Thereby helps in controlling seizures. Migrid Crono-500Mg Cr Tablet increases the amount of a chemical substance called GABA, this helps block the nerve transmission across the brain and provides a calming effect.
 
You are advised to take Migrid Crono-500Mg Cr Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as headache, sleepiness, drowsiness, impaired coordination, apathy (lack of interest), irregular periods and weight gain. Talk to your doctor if you experience these side-effects persistently.
 
Do not take Migrid Crono-500Mg Cr Tablet if you are pregnant, as it could cause serious congenital disabilities. If you are of child-bearing age, use effective contraception while taking Migrid Crono-500Mg Cr Tablet . Consult your doctor before taking Migrid Crono-500Mg Cr Tablet if you are breastfeeding. Migrid Crono-500Mg Cr Tablet causes drowsiness and dizziness, so avoid driving unless you are alert. Avoid consuming alcohol along with Migrid Crono-500Mg Cr Tablet as it could lead to an increased risk of seizures. Care should be taken while giving Migrid Crono-500Mg Cr Tablet to children below 3 years as there is a higher risk of liver intoxication during the first 6 months of treatment.

Uses of Migrid Crono-500Mg Cr Tablet

Epilepsy, Mood disorder, Migraine

Directions for Use

Take Migrid Crono-500Mg Cr Tablet with or 1hour prior food. Swallow Migrid Crono-500Mg Cr Tablet a whole with a glass of water, do not chew, or break it.

Medicinal Benefits

Migrid Crono-500Mg Cr Tablet is a combination of two drugs, namely: Sodium valproate and Valproic acid. Migrid Crono-500Mg Cr Tablet is used to treat epilepsy/seizures/fits, mood disorders and to prevent migraine headaches. Migrid Crono-500Mg Cr Tablet decreases the excessive and abnormal nerve activity in the brain, thereby controlling seizures. Migrid Crono-500Mg Cr Tablet is used to treat certain forms of epilepsy such as petit mal epilepsy (short-term unconsciousness due to disorder in the brain), myoclonic seizures (sudden muscle contractions) and grand mal epilepsy (severe muscle contractions which lead to unconsciousness). Migrid Crono-500Mg Cr Tablet may also be used to treat epilepsy which does not sufficiently respond to other anticonvulsant drugs, such as epilepsy which is not associated with movements and epilepsy with symptoms affecting perception and deliberate movements. Migrid Crono-500Mg Cr Tablet is used to treat both partial seizures (affects only a part of the brain) and generalised seizures (affects the entire brain).

Storage

Keep Migrid Crono-500Mg Cr Tablet out of reach and sight of children.
Side effects of Migrid Crono-500Mg Cr Tablet
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
  • Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
  • Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
  • Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
  • If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
  • In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
  • Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
  • If you experience severe bleeding or bruising, seek emergency medical attention immediately.
  • Get plenty of rest and sleep.
  • Keep your body warm.
  • Drink plenty of fluids to stay hydrated.
  • Avoid strenuous activities.
  • Maintain good hygiene to prevent flu from spreading.
  • Eat a balanced diet high in nutrients and low in sugar.
  • Include fruits, vegetables, and leafy greens rich in vitamins C and K.
  • Brush and floss regularly twice a day with fluoride toothpaste and once a day with floss.
  • Use a soft or extra-soft toothbrush.
  • Reduce stress to minimize inflammation and gum bleeding.
  • Avoid tobacco products as smoking can worsen gum disease.
  • Stay hydrated by drinking water to flush bacteria and food particles.
  • Consider vitamin supplements if deficient to support gum health.
  • Use an antimicrobial mouthwash to reduce bacteria and prevent bleeding.
  • Swish with coconut oil for its antibacterial properties to reduce plaque.
  • Drink green tea rich in catechin to reduce inflammation from oral bacteria.
  • Consult your dentist if gums bleed consistently.
  • Apply a cold compress to the affected area for 10 to 15 minutes multiple times a day.
  • Elevate your head while resting or sleeping to reduce fluid accumulation.
  • Drink lots of water to eliminate excess fluids.
  • Limit salty foods as they can cause water retention.
  • To stimulate lymphatic drainage, gently massage the swollen area.

Drug Warnings

Do not take Migrid Crono-500Mg Cr Tablet if you are allergic to any of its contents, if you have/ had liver problems, porphyria (blood disorder) or if you are susceptible to bleeding. Inform your doctor if you have inflammation-like diseases, bone marrow damage or kidney problems. Talk to your doctor if you experience weakness, loss of appetite, lack of interest, recurrence or worsening of seizures, prolonged bleeding or abdominal pain while taking Migrid Crono-500Mg Cr Tablet . Consult your doctor immediately if you experience suicidal tendencies while taking Migrid Crono-500Mg Cr Tablet . Please do not stop taking Migrid Crono-500Mg Cr Tablet without consulting your doctor to avoid the worsening of seizures. Do not take Migrid Crono-500Mg Cr Tablet if you are pregnant, as it could cause serious birth defects. If you are of child-bearing age, use effective contraception while taking Migrid Crono-500Mg Cr Tablet . Consult your doctor before taking Migrid Crono-500Mg Cr Tablet if you are breastfeeding. Migrid Crono-500Mg Cr Tablet causes drowsiness and dizziness, so avoid driving unless you are alert. Avoid consuming alcohol along with Migrid Crono-500Mg Cr Tablet as it could lead to increased risk of seizures. Care should be taken while giving Migrid Crono-500Mg Cr Tablet to children below 3 years as there is a higher risk of liver intoxication during the first 6 months of treatment.

Drug-Drug Interactions

verifiedApollotooltip
Sodium ValproateSodium phenylbutyrate
Critical
Sodium ValproateBuprenorphine
Severe

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Diet & Lifestyle Advise

  • A ketogenic diet (low in carbohydrates and high in fats) is recommended for children with epilepsy. This diet helps in utilising fat instead of glucose for the generation of energy.
  • Atkins diet (high fat and controlled carbohydrates) is recommended for adolescents and adults.
  • Exercising regularly helps in maintaining weight and improving overall health. 
  • Rest well, and get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity and improves coping skills.
  • Have a seizure response plan; this helps those around you know what to do.
  • Prepare your living area; small changes may help in reducing the risk of physical injury during a seizure.
  • Understand what triggers seizures and try reducing or avoiding them.
  • Please pay attention to overall health as it can help in reducing seizure activity.
  • Install an alarm or emergency device to get assistance during a seizure attack.

Habit Forming

No

Therapeutic Class

ANTICONVULSANT

Migrid Crono-500Mg Cr Tablet Substitute

Substitutes safety advice

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Sunny S

Reviewed By

Sunny S

MBBS

Last Updated

Jul 8, 2025 | 9:32 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

FAQs

Migrid Crono-500Mg Cr Tablet decreases the excessive and abnormal nerve activity in the brain. Migrid Crono-500Mg Cr Tablet increases the amount of a chemical substance called GABA, this helps in blocking the nerve transmission across the brain and provides a calming effect. Thereby helps in controlling seizures.

Do not discontinue Migrid Crono-500Mg Cr Tablet without consulting your doctor. To treat your condition effectually, continue taking Migrid Crono-500Mg Cr Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Migrid Crono-500Mg Cr Tablet ; your doctor will reduce the dose gradually to avoid worsening of seizures.

Migrid Crono-500Mg Cr Tablet may cause thrombocytopenia (low levels of platelets). This might increase the risk of bleeding and bruising. Be cautious while using sharp objects. Consult your doctor if you notice unexplained bleeding or bruising.

Migrid Crono-500Mg Cr Tablet may cause weight gain due to an increase in appetite. Maintain a healthy weight by following a proper diet and exercising regularly.

Migrid Crono-500Mg Cr Tablet may increase the effect of aspirin when taken together. Please consult your doctor before taking Migrid Crono-500Mg Cr Tablet with aspirin to avoid unpleasant side-effects. Migrid Crono-500Mg Cr Tablet and aspirin should not be given together to children below 3 years as it could lead to liver intoxication.

Drug-Drug Interactions Checker List

  • ASPIRIN
  • PHENOBARBITAL
  • PHENYTOIN
  • PRIMIDONE
  • CARBAMAZEPINE
  • LAMOTRIGINE
  • FELBAMATE
  • ZIDOVUDINE
  • AMITRIPTYLINE
  • SERTRALINE
  • QUETIAPINE
  • OLANZAPINE
  • RISPERIDONE
  • LEVONORGESTREL
  • MEFLOQUINE
  • CIMETIDINE
  • IMIPENEM
  • MEROPENEM
  • ERYTHROMYCIN
  • CHOLESTYRAMINE
  • CLONAZEPAM
  • DIAZEPAM

Special Advise

  • Regular monitoring of blood count is advised while taking Migrid Crono-500Mg Cr Tablet as it may cause spontaneous bleeding or bruising.
  • Inform your doctor that you are taking Migrid Crono-500Mg Cr Tablet if you are due to have any surgery or dental intervention.
  • Consult your doctor if you experience irregular periods while taking Migrid Crono-500Mg Cr Tablet .
  • If you are of child-bearing age, use effective contraception while taking Migrid Crono-500Mg Cr Tablet .

Disease/Condition Glossary

Epilepsy/Seizures: Seizures, also known as fits or convulsions, is a single occurrence of abnormal electrical activity in the brain, whereas epilepsy is a chronic neurological disorder characterized by recurrent seizures. The possible causes of epilepsy include traumatic brain injury, scarring on the brain after a brain injury, high fever, stroke, vascular diseases, lack of oxygen to the brain, brain tumours, and genetic disorders. Symptoms include mood changes, anxiousness, nausea, dizziness, weakness, headache, muscle jerking, spasms, loss of balance, teeth clenching, rapid blinking or eye movements, biting the tongue, confusion, and loss of consciousness.

Mood disorder: It is a mental health disorder which mainly affects a person's emotional state. A mood disorder is associated with episodes of mood swings ranging from manic highs to depressive lows. 

Migraine: Migraine is a neurological condition which is characterised by an intense, debilitating headache. Hormonal changes, stress, lack or excess of sleep, bright lights, loud sounds, certain foods and drinks can trigger migraine headaches. Symptoms of migraine include throbbing pain in one particular area with varying intensity, nausea, vomiting, numbness or tingling sensation, difficulty speaking, and sensitivity to sound and light. 

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