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ORAL

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Expires on or after

Jan-27

for this medicine

About MONOSPRIN 30MG TABLET

MONOSPRIN 30MG TABLET belongs to a class of antianginals, which is used to treat angina pectoris. Angina pectoris is discomfort in the chest or chest pain, which generally occurs due to coronary artery disease (CAD) when an adequate amount of oxygen and blood is not reaching the heart and its muscles. It can also be due to the blockage of the heart's arteries. It helps prevent any further attack of angina by making the heart work more efficiently.

MONOSPRIN 30MG TABLET is a combination of medication containing Isosorbide Mononitrate and aspirin. Isosorbide Mononitrate is a powerful vasodilator (widens blood vessels). It works by forming the free radical nitric oxide (NO) inside our body which leads to relaxation of the muscles of blood vessels, especially of the heart leading to proper blood flow towards the heart muscle, which has been working under immense pressure due to decreased blood flow to it. Aspirin has an antithrombotic action that interferes with platelet functioning and does not let them stick together, thus helping to prevent or reduce blood clots. Altogether, MONOSPRIN 30MG TABLET is helpful in treating and preventing episodes of angina.

Take MONOSPRIN 30MG TABLET as prescribed by the doctor. The dose of MONOSPRIN 30MG TABLET can vary depending upon your condition and the severity of the condition. Also, it is recommended to complete the course of medicine even if you feel better. The common side effects of MONOSPRIN 30MG TABLET include increased bleeding tendency, stomach pain, diarrhoea, headache, indigestion, dizziness, and itching. In case of any discomfort, speak with a doctor.

Take MONOSPRIN 30MG TABLET only if the doctor prescribes you. Never encourage self-medication or suggest your medicine to someone else. You should not take MONOSPRIN 30MG TABLET if you have severe anemia, low blood volume, gout, severe kidney or liver problems, blood clotting disorder, or ulcer in the stomach or intestine. Also, do not take MONOSPRIN 30MG TABLET if you are taking medicines like methotrexate(for cancer) and medicines for erectile dysfunction such as sildenafil, vardenafil, and tadalafil. Check with your doctor if you're pregnant, currently breastfeeding, or taking any other prescribed or non-prescribed medicines. Also, do not stop MONOSPRIN 30MG TABLET abruptly, as it may lead to severe side effects. Avoid alcohol consumption as it might lead to very low blood pressure.

Uses of MONOSPRIN 30MG TABLET

Angina Pectoris

Directions for Use

Take MONOSPRIN 30MG TABLET as advised by the doctor. Swallow it as a whole with a glass of water. Do not chew or crush it.

Medicinal Benefits

MONOSPRIN 30MG TABLET belongs to a class of medicines called antianginal. It is a combination of medication containing Isosorbide Mononitrate and aspirin. Isosorbide Mononitrate is a powerful vasodilator that operates by relaxing the blood vessels of the heart, reducing the stress on the heart and making it easier to pump blood. Angina usually feels like tight chest pain, neck or arm area. The pain originates from the heart muscle and is a sign that part of it is not getting enough oxygen for the amount of work it is doing. Aspirin works as an antithrombotic action that affects platelet functioning and does not let them stick together, thus helping to prevent or reduce blood clots. As a combination medication, MONOSPRIN 30MG TABLET reduces the risk of further heart attack or stokes or of dying from one of these atherothrombotic events.

Storage

Store in a cool and dry place away from sunlight

Side Effects of MONOSPRIN 30MG TABLET

  • Stomach pain
  • Diarrhea
  • Headache
  • Dizziness
  • Itching
  • Flushing of skin
  • Increased bleeding tendency

Drug Warnings

Inform to your doctor or pharmacist before taking MONOSPRIN 30MG TABLET if you have underactive thyroid gland, severe liver or kidney problems, serious damage to heart, glaucoma, gout, high blood pressure, or if you are a women with heavy menstrual periods. Seek medical help immediately if you experience unusual bleeding symptoms, fainting or collapse, or allergic symptoms. Check with your doctor if you're pregnant, currently breastfeeding or taking any other prescribed or non-prescribed medicines. Also, do not stop MONOSPRIN 30MG TABLET abruptly as it may lead to severe side-effects. Avoid alcohol consumption as it might lead to very low blood pressure. Drink plenty of liquids while taking this medicine as advised by your doctor.

Drug-Drug Interactions

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Isosorbide mononitrateRiociguat
Critical
Isosorbide mononitrateTadalafil
Critical

Drug-Drug Interactions

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Isosorbide mononitrateRiociguat
Critical
How does the drug interact with Monosprin 30mg Tablet:
Taking Riociguat with Monosprin 30mg Tablet can cause low blood pressure.

How to manage the interaction:
Taking Monosprin 30mg Tablet with Riociguat is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience dizziness, lightheadedness, fainting, headache, flushing, heart palpitations, priapism in males (persistent and painful erection unrelated to sexual activity). Do not discontinue any medications without consulting a doctor.
Isosorbide mononitrateTadalafil
Critical
How does the drug interact with Monosprin 30mg Tablet:
Coadministration of Tadalafil with Monosprin 30mg Tablet can increase the risk or severity of low blood pressure.

How to manage the interaction:
Taking Monosprin 30mg Tablet with Tadalafil is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience dizziness, or heart palpitations. Do not discontinue any medications without consulting a doctor.
AspirinKetorolac tromethamine
Critical
How does the drug interact with Monosprin 30mg Tablet:
Combining Ketorolac tromethamine with Monosprin 30mg Tablet can increase the risk of adverse effects.

How to manage the interaction:
Taking Monosprin 30mg Tablet with Ketorolac tromethamine is not recommended, as it results in an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor’s advice.
AspirinKetorolac
Critical
How does the drug interact with Monosprin 30mg Tablet:
Co-administration of Ketorolac and Monosprin 30mg Tablet may increase the risk of side effects.

How to manage the interaction:
Taking Ketorolac with Monosprin 30mg Tablet is not recommended but can be taken together if prescribed by a doctor. However, consult a doctor if you experience unusual bleeding or bruising, dizziness, tarry stools, coughing up or vomiting fresh or dried blood, severe headache and weakness. Do not stop using any medications without talking to a doctor.
Isosorbide mononitrateDihydroergotamine
Severe
How does the drug interact with Monosprin 30mg Tablet:
Taking Monosprin 30mg Tablet together with dihydroergotamine can increase the effects of dihydroergotamine.

How to manage the interaction:
Although taking Monosprin 30mg Tablet and dihydroergotamine together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience an irregular heartbeat, nausea, vomiting, weakness, or coldness, numbness, chest pain or pain in the hands, feet, arms, or legs. Do not discontinue any medications without consulting a doctor.
Isosorbide mononitrateSodium nitrite
Severe
How does the drug interact with Monosprin 30mg Tablet:
Taking Monosprin 30mg Tablet with sodium nitrite may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although taking Monosprin 30mg Tablet and sodium nitrite together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
Isosorbide mononitrateTizanidine
Severe
How does the drug interact with Monosprin 30mg Tablet:
Taking Monosprin 30mg Tablet with tizanidine will have an additive effect and may lower blood pressure.

How to manage the interaction:
Although taking Monosprin 30mg Tablet and tizanidine together can possibly result in an interaction, but it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as headache, dizziness, lightheadedness, fainting, and/or pulse or heart rate changes. Do not stop using any medications without consulting doctor.
AspirinDalteparin
Severe
How does the drug interact with Monosprin 30mg Tablet:
Using dalteparin with Monosprin 30mg Tablet, may enhance the risk of bleeding problems.

How to manage the interaction:
Although there is a possible interaction between Monosprin 30mg Tablet and dalteparin, you can take these medicines together if prescribed by a doctor. However, if you notice unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness while taking these drugs, inform a doctor immediately. Do not stop using any medications without consulting a doctor.
AspirinRegorafenib
Severe
How does the drug interact with Monosprin 30mg Tablet:
When regorafenib is used with Monosprin 30mg Tablet, the risk of bleeding may increase.

How to manage the interaction:
Although there is a possible interaction between Monosprin 30mg Tablet and regorafenib, you can take these medicines together if prescribed by a doctor. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
AspirinRamucirumab
Severe
How does the drug interact with Monosprin 30mg Tablet:
Combined use of Monosprin 30mg Tablet with ramucirumab may result in gut ulcers and bleeding.

How to manage the interaction:
There may be a possibility of interaction between Monosprin 30mg Tablet and Ramucirumab, but it can be taken if prescribed by a doctor. However, if you notice unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Adopting a heart-healthy lifestyle will help you keep your cholesterol and blood pressure down, keep your arteries clear and avoid angina.
  • Limit or completely avoid the intake of alcohol as it may worsen the side effects, including dizziness.
  • According to BMI, manage weight and lose extra pounds. Excess body weight puts extra strain on the heart.
  • Include more vegetables and fruits in your diet as these foods are a good source of vitamins and minerals and improve heart health.
  • Quit smoking, as smoking is a significant cause of heart problems. Any smoking will gradually worsen the condition, so stopping smoking is the only step a person can take to improve their health.
  • Being physically active will prevent the medical condition from getting worse.
  • Exercise, walking, and running help to control cholesterol levels and blood pressure, improving heart health.

Habit Forming

No

Therapeutic Class

ANTIANGINALS

MONOSPRIN 30MG TABLET Substitute

Substitutes safety advice
  • Isoloprin 30mg/75mg Capsule

    by Others

    2.88per tablet
  • NITREN 30MG/75MG CAPSULE

    by Others

    2.11per tablet
  • Nitroprin Tablet

    by Others

    2.68per tablet
  • Vasoprin LS 30 mg/75 mg Tablet

    by Others

    0.85per tablet

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • SILDENAFIL
  • TADALAFIL
  • VARDENAFIL
  • METHOTREXATE
  • CICLOSPORIN
  • MIFEPRESTONE
  • ZAFIRLUKAST
  • SODIUM VALPROATE
  • NITROGLYCERIN
  • NIFEDIPINE
  • WARFARIN

Special Advise

  • Avoid vigorous physical activity that may aggravate anginal attack.
  • Avoid smoking.
  • A patient should avoid places where airflow is restricted.

Disease/Condition Glossary

Angina: Angina or chest pain is the most common indication of heart disease caused due to decreased blood flow to heart muscles. The heart is dependent on oxygen for its functioning and pumping of blood, yet sometimes due to various genetic and environmental reasons, the blood vessels supplying blood to the heart narrow unexpectedly, causing decreased blood flow to the heart. This abrupt decrease in blood flow leads to increased stress on the heart to pump blood towards different organs, causing an event of acute chest pain that starts from the arm along the jaw and finally involves the chest. Angina pectoris is of 3 types:

1) Stable Angina: It is the most common type in which blood flow to the heart is low compared to what it needs to function, caused by increased physical activity.

2) Unstable Angina: It is the most lethal type in which blood supply to the heart decreases abruptly due to blockage of an artery by a clot etc.

3) Variant Angina: It occurs at rest due to spasmodic narrowing of the artery.

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