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Written By ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

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Whats That

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Composition :

NALTREXONE-50MG

Manufacturer/Marketer :

Maan Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Nalsup Tablet

Nalsup Tablet belongs to the class of medications called 'opioid-antagonist' used to treat alcohol dependence (chronic alcoholism) and opioid dependence. Alcohol dependence is a chronic medical condition that typically includes a current or past history of excessive drinking, a strong craving for alcohol, continued use despite repeated problems with drinking, and an inability to control alcohol consumption. Opioid dependence is a condition when someone becomes physically dependent on a substance; their body relies on it to avoid withdrawal.

Nalsup Tablet contains 'naltrexone'. It works by blocking the effect of opioid receptors and decreasing cravings and urges to use alcohol or opioids. Still, it is used along with counselling and social support to help patients dependent on alcohol abstain from drinking alcoholic drinks.

Nalsup Tablet should be taken as prescribed by your doctor. Some cases Nalsup Tablet may cause certain side effects such as nausea, vomiting, injection site reactions (including induration, pruritus, nodules and swelling), muscle cramps, dizziness or syncope, drowsiness or sedation, anorexia (eating disorder), decreased appetite or other appetite disorders, hepatic enzyme abnormalities, cold, insomnia, and toothache. Everyone need not experience the above side effects. If Nalsup Tablet causes any serious discomfort, speak with a doctor.

Before taking the Nalsup Tablet, let your doctor know about all your medical conditions (especially hepatitis or liver failure), allergic reactions, and all medications you are using (especially opioid analgesics). And also, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Nalsup Tablet may cause dizziness and sedation; therefore, avoid driving vehicles or operating machinery until you return to normal. Nalsup Tablet usage is contraindicated in patients with current physiologic opioid dependence, patients in acute opioid withdrawal, or any individual who has failed the naloxone challenge test or has a positive urine screen for opioids. If you notice mood changes while taking Nalsup Tablet, please consult a doctor immediately.

Uses of Nalsup Tablet

Alcohol dependence and opioid dependence

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Nalsup Tablet contains naltrexone. It belongs to the class of medications called 'opioid-antagonist' used to treat alcohol dependence (chronic alcoholism) and opioid dependence. It works by blocking the effect of opioid receptors and decreasing cravings and urges to use alcohol or opioids. Still, it is used along with counselling and social support to help patients dependent on alcohol abstain from drinking alcoholic drinks.

Storage

Store in a cool and dry place away from sunlight
Side effects of Nalsup Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 step-by-step strategies to manage the side effect of "inability to sleep" caused by medication usage:
  • Prepare for a restful night's sleep: Develop a calming pre-sleep routine, like reading or meditation, to help your body relax and prepare for sleep.
  • Create a sleep-conducive Environment: Make bedroom a sleep haven by ensuring it is quiet, dark and calm.
  • Follow a Sleep Schedule: Go to bed and get up at the same time every day to help regulate your body's internal clock and increase sleep quality.
  • Try relaxing techniques like deep breathing, mindfulness meditation and any others.
  • Limit stimulating activities before bedtime: Avoid stimulating activities before bedtime to improve sleep quality.
  • Monitor Progress: Keep track of your sleep patterns to identify areas for improvement.
  • Consult a doctor if needed: If these steps don't improve your sleep, consult a doctor for further guidance and therapy.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the steps to manage Joint Pain caused by medication usage:
  • Please inform your doctor about joint pain symptoms, as they may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Your doctor may prescribe common pain relievers if necessary to treat joint discomfort.
  • Maintaining a healthy lifestyle is key to relieving joint discomfort. Regular exercise, such as low-impact sports like walking, cycling, or swimming, should be combined with a well-balanced diet. Aim for 7-8 hours of sleep per night to assist your body in repairing and rebuilding tissue.
  • Applying heat or cold packs to the affected joint can help reduce pain and inflammation.
  • Please track when joint pain occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • If your joint pain is severe or prolonged, consult a doctor to rule out any underlying disorders that may require treatment.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.

Drug Warnings

Before your doctor prescribes the Nalsup Tablet, inform them of all your medical conditions (particularly hepatitis or liver failure), allergic reactions (with food and medications), and medications you are taking (especially opioid analgesics). Also, let your doctor know if you are pregnant, planning to become pregnant, or breastfeeding. Nalsup Tablet usage is contraindicated in patients with current physiologic opioid dependence, patients in acute opioid withdrawal, or any individual who has failed the naloxone challenge test or has a positive urine screen for opioids. Nalsup Tablet may cause dizziness and sedation; therefore, avoid driving vehicles or operating machinery until you return to normal. Do not use other medications without the doctor's notice, especially opioid-containing ones.

Drug-Drug Interactions

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NaltrexoneMethadone
Critical
NaltrexoneDezocine
Critical

Drug-Drug Interactions

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NaltrexoneMethadone
Critical
How does the drug interact with Nalsup Tablet:
Taking Methadone with Nalsup Tablet can increase the risk or severity of harmful side effects.

How to manage the interaction:
Taking Methadone with Nalsup Tablet is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
NaltrexoneDezocine
Critical
How does the drug interact with Nalsup Tablet:
Coadministration of Nalsup Tablet with Dezocine can block the effects of Dezocine and make the medication less effective.

How to manage the interaction:
Taking Nalsup Tablet with Dezocine is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
NaltrexonePentazocine
Critical
How does the drug interact with Nalsup Tablet:
Taking Nalsup Tablet with Pentazocine can reduce the effects of pentazocine and make the medication less effective.

How to manage the interaction:
Taking Pentazocine with Nalsup Tablet is generally avoided, but can be taken together if prescribed by a doctor. However, if you experience any symptoms like nausea, vomiting, diarrhoea, aches, fever, runny nose, sneezing, nervousness, irritability, shivering, and abdominal cramps, contact a doctor immediately. Do not stop using any medications without consulting a doctor.
NaltrexoneMorphine
Critical
How does the drug interact with Nalsup Tablet:
Using Morphine with Nalsup Tablet can block morphine's effects, which reduces its ability to effectively treat illness.

How to manage the interaction:
Taking Morphine with Nalsup Tablet together is generally avoided as it can result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
NaltrexonePethidine
Critical
How does the drug interact with Nalsup Tablet:
Taking Pethidine with Nalsup Tablet can block the effects of Pethidine and make the medication less effective.

How to manage the interaction:
Taking Pethidine with Nalsup Tablet is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
NaltrexoneOpium
Critical
How does the drug interact with Nalsup Tablet:
Combining Nalsup Tablet with Opium can block the effects of opium, which reduces its ability to effectively treat your illness.

How to manage the interaction:
Taking Nalsup Tablet with Opium is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience nausea, vomiting, diarrhoea, aches, fever, runny nose, sneezing, nervousness, irritability, shivering, and abdominal cramps, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
NaltrexoneTapentadol
Critical
How does the drug interact with Nalsup Tablet:
Using Tapentadol together with Nalsup Tablet can block the effects of tapentadol, which reduces its ability to effectively treat your illness.

How to manage the interaction:
Taking Tapentadol with Nalsup Tablet is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, blurred vision, muscle spasm or stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhoea call a doctor right away. Do not stop using any medications without a doctor’s advice.
NaltrexoneLeflunomide
Severe
How does the drug interact with Nalsup Tablet:
Taking Leflunomide and Nalsup Tablet can increase the risk or severity of liver problems.

How to manage the interaction:
Although there is an interaction between Leflunomide and Nalsup Tablet, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
NaltrexoneNaloxegol
Severe
How does the drug interact with Nalsup Tablet:
Coadministration of Nalsup Tablet and Naloxegol can increase the effects of Naloxegol. This can increase the risk or severity of side effects.

How to manage the interaction:
Although taking Nalsup Tablet and Naloxegol together can evidently cause an interaction, it can be taken if your doctor has suggested it. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A patient is advised to have a diet that increases serotonin levels which makes a person feel good & involves eating foods high in carbohydrates, especially the complex carbohydrates present in starchy food items like legumes (e.g., beans, lentils and peas), root vegetables (e.g., potatoes and carrots), pasta and bread. Eating such foods in combination with protein in meals will benefit.
  • Deficiencies in B-complex vitamins such as thiamine, folate or folic acid, and B12 are common with alcoholism, and inadequate stores of other B vitamins and vitamin C frequently occur. A patient should consume supplements and vitamins as per their doctor's recommendation.
  • Malnutrition is common during alcohol consumption and is revealed slowly and gradually. The patient becomes very tired and develops a weaker immune system, which means the patient is more susceptible to infections. These problems need to be identified and treated during the recovery process—ideally by a team of healthcare professionals.
  • The patient should change his drinking priorities and prefer drinks like apple cider, vanilla shake, mixing juice or lemonade with sparkling water etc.
  • Get physical activity and enough rest.
  • Reduce caffeine and stop smoking, if possible.

Habit Forming

Not enough scientific literature available around this hence it is best to consult your physician

Therapeutic Class

OPIOID ANTAGONISTS

Nalsup Tablet Substitute

Substitutes safety advice
  • Naltima 50 Tablet 10's

    by Others

    91.44per tablet
  • Nodict Tablet 10's

    by Others

    93.60per tablet
  • Addtrex 50 mg Tablet 10's

    by AYUR

    72.14per tablet
  • Naltox-50 Tablet 10's

    by Others

    76.82per tablet
  • Naltrawave Tablet 10's

    by AYUR

    77.40per tablet

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Nalsup Tablet works by blocking the effect of opioid receptors and decreasing cravings and urges to use alcohol or opioids, but it is used along with counselling and social support to help patients who are dependent on alcohol abstain from drinking alcoholic drinks.

No, Nalsup Tablet should not be used with an opioid analgesic, as it may cause serious adverse effects of the drug. If you have any concerns, please discuss them with your doctor.

Before taking the Nalsup Tablet, inform your doctor about your medical conditions (particularly hepatitis or liver failure), allergic reactions, and medications you are already taking (especially opioid analgesics). Also, let your doctor know if you are pregnant, planning to become pregnant, or breastfeeding.

Take the missed dose as soon as you remember. Take the rest of the day's doses at evenly spaced intervals unless otherwise directed by your doctor.

Using Nalsup Tablet in any individual who has failed the naloxone challenge test or has a positive urine screen for opioids is contradicted.

Drug-Drug Interactions Checker List

  • CODEINE
  • HYDROCODONE
  • LEFLUNOMIDE
  • DROPERIDOL

Special Advise

  • It is recommended to monitor liver function tests regularly.
  • Patients should be opioid-free for at least 7-10 days before initiating the treatment.
  • Strictly warn patients against the use of opioids while on Nalsup Tablet.
  • Monitor for injection-site reactions.

Disease/Condition Glossary

Alcohol dependence: Alcohol dependence is a chronic medical condition that typically includes a current or past history of excessive drinking, a strong craving for alcohol, continued use despite repeated problems with drinking, and an inability to control alcohol consumption. Symptoms include blackout, dizziness, shakiness, craving, sweating, aggression, anxiety, nausea or vomiting, loneliness, delirium or fear, problems with coordination, slurred speech, or tremor.

Opioid-dependence: Opioid dependence is a condition when someone becomes physically dependent on a substance; their body relies on it to avoid withdrawal. In this case, instead of making enough of its own opioids, the body has begun to rely on outside opioids to maintain normal function. Symptoms include craving or sweating, euphoria or general discontent, physical substance dependence, chronic constipation, small pupils, nausea, reduced sex drive, sensitivity to pain, shallow breathing, or slurred speech.

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