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Consume Type

ORAL

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Not Returnable

Expires on or after

Apr-24

for this medicine

About Natrilam 10 Tablet 10's

Natrilam 10 Tablet 10's belongs to the class of medication called 'anti-hypertensive drugs', primarily used to treat hypertension (high blood pressure). Hypertension is a medical condition in which the blood exerts high pressure (force exerted by circulating blood) against the blood vessel's walls. This condition makes the heart work harder in pumping blood to the whole body. Hypertension can cause severe health complications, including stroke, heart failure, heart attack and kidney failure.

Natrilam 10 Tablet 10's consists of Amlodipine and Indapamide.  Amlodipine relaxes blood vessels so that blood passes through them easily, thereby lowering blood pressure. Indapamide inhibits excess salt absorption in the body, resulting in increased chloride, sodium, and water excretion through urine. This diuresis process (increased urine production) and excess salts and fluid removal help lower blood pressure. 

The common side effects of Natrilam 10 Tablet 10's include nausea, stomach pain, headache, sleepiness, ankle swelling, flushing (warm sensation in the face, ears, neck, and trunk), palpitations (pounding heartbeat), constipation, muscle pain, and tiredness. Most of these side effects resolve gradually over time and do not usually require medical attention. However, if you notice any side effects that are not manageable, it is advised to consult your doctor.

Try not to stop taking this medicine on your own. Stopping Natrilam 10 Tablet 10's may worsen your condition and increase the risk of a heart attack. Tell your doctor if you are sensitive to Natrilam 10 Tablet 10's, have any kidney/liver diseases, or have heart problems like aortic/mitral stenosis (reduced blood flow from the left atrium to the left ventricle due to narrowing of the mitral valve). Natrilam 10 Tablet 10's is not recommended for use in pregnancy and breastfeeding. Natrilam 10 Tablet 10's may cause dizziness; hence it is advised to drive only when you are alert.

Uses of Natrilam 10 Tablet 10's

High blood pressure (hypertension)

Directions for Use

Swallow this medicine as a whole with a glass of water. Do not crush, chew or break it.

Medicinal Benefits

Natrilam 10 Tablet 10's is composed of two medicines, namely: Amlodipine and Indapamide. Amlodipine belongs to the class of calcium channel blockers that relaxes blood vessels so that blood passes through them easily, lowering blood pressure. Indapamide is a thiazide diuretic that inhibits excess salt absorption in the body, resulting in increased chloride, sodium, and water excretion through urine. This diuresis process (increased urine production) and excess salts and fluid removal help lower blood pressure.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Natrilam 10 Tablet 10's

  • Blurred Vision 
  • Sweating
  • Tiredness 
  • Dehydration 
  • Constipation 
  • Dizziness 
  • Headache 
  • Nausea 
  • Cold hands or feet 
  • Muscle cramps
  • Difficulty breathing
  • Tightness in the chest

Drug Warnings

Do not use Natrilam 10 Tablet 10's if you are allergic to any of its components. Let your doctor know if you have any history of severe kidney or liver diseases, low potassium levels (hypokalaemia), chest pain (angina), poor blood circulation or controlled heart failure, first-degree heart block, diabetes, thyrotoxicosis (a condition caused by an overactive thyroid gland), liver problems and adrenal gland diseases. Let your doctor know if you have anuria (kidneys aren't producing urine), fluid or electrolyte imbalance, lupus erythematosus (an autoimmune inflammatory disease-causing scaly red patches on the skin), gout, abnormal heart rhythms, thyroid disorders or asthma. Consult your doctor if you are pregnant or breastfeeding. Natrilam 10 Tablet 10's can increase the chances of light-headedness, so rise slowly if you are sitting/lying and avoid operating any machine or doing any work that needs mental alertness. Natrilam 10 Tablet 10's is not recommended in people less than 18 years of age.

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
IndapamideProtriptyline
Critical

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
How does the drug interact with Natrilam 10 Tablet:
Using Natrilam 10 Tablet together with dantrolene may increase the risk of hyperkalemia (high blood potassium).

How to manage the interaction:
Taking Natrilam 10 Tablet with Dantrolene can cause an interaction, consult a doctor before taking it. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
IndapamideProtriptyline
Critical
How does the drug interact with Natrilam 10 Tablet:
Taking Protriptyline along with Natrilam 10 Tablet can lead to serious heart problems.

How to manage the interaction:
Taking Protriptyline with Natrilam 10 Tablet is not recommended, but can be taken if prescribed by the doctor.
IndapamideDroperidol
Critical
How does the drug interact with Natrilam 10 Tablet:
Taking Droperidol with Natrilam 10 Tablet can lead to severe heart problems.

How to manage the interaction:
Taking Droperidol with Natrilam 10 Tablet is not recommended, but can be taken if prescribed by the doctor.
IndapamideThioridazine
Critical
How does the drug interact with Natrilam 10 Tablet:
Taking Natrilam 10 Tablet with Thioridazine can increase the risk of heart problems.

How to manage the interaction:
Taking Thioridazine with Natrilam 10 Tablet is not recommended, but can be taken if prescribed by the doctor.
AmlodipineEnzalutamide
Severe
How does the drug interact with Natrilam 10 Tablet:
Using a combination of Natrilam 10 Tablet and enzalutamide may drastically lower Natrilam 10 Tablet blood levels, making the medicine less effective.

How to manage the interaction:
Taking Natrilam 10 Tablet with enzalutamide can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipineCarbamazepine
Severe
How does the drug interact with Natrilam 10 Tablet:
Coadministration of Natrilam 10 Tablet and carbamazepine together may significantly reduce Natrilam 10 Tablet blood levels, making the medicine less effective.

How to manage the interaction:
Although there is an interaction between Natrilam 10 Tablet with carbamazepine, it can be taken if a doctor has advised it. However, if you experience any unusual symptoms contact the doctor immediately. Do not stop using any medications without talking to a doctor.
AmlodipineIdelalisib
Severe
How does the drug interact with Natrilam 10 Tablet:
Coadministration of Natrilam 10 Tablet and Idelalisib may raise Natrilam 10 Tablet levels in the blood this may lead to serious side effects (irregular heart rhythm, fluid retention, swelling, heart failure, and abnormally low blood pressure).

How to manage the interaction:
Although taking Natrilam 10 Tablet with idelalisib can result in an interaction, it can be taken if a doctor has advised it. However, if you experience dizziness or fainting, sudden, unexplained weight gain, swelling of the hands, ankles, or feet, chest discomfort, or trouble breathing while taking these drugs, consult the doctor. Use caution while getting up from a sitting or sleeping position and avoid driving or using dangerous machinery. Do not stop using any medications without a doctor's advice.
AmlodipineItraconazole
Severe
How does the drug interact with Natrilam 10 Tablet:
Coadministration of Natrilam 10 Tablet with itraconazole may significantly raise the blood levels and effects of Natrilam 10 Tablet.

How to manage the interaction:
Natrilam 10 Tablet and itraconazole may interact, but if prescribed by a doctor, they can be used together. Consult a doctor if you develop chest discomfort, trouble breathing, dizziness or fainting, swelling of the hands, ankles, or feet, or any other of these symptoms. Without consulting a doctor, never stop taking any medication.
AmlodipinePrimidone
Severe
How does the drug interact with Natrilam 10 Tablet:
Using Natrilam 10 Tablet and primidone together may lower Natrilam 10 Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although co-administration of Natrilam 10 Tablet with primidone can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipinePhenobarbital
Severe
How does the drug interact with Natrilam 10 Tablet:
Using phenobarbital and Natrilam 10 Tablet may drastically lower Natrilam 10 Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although co-administration of phenobarbital with Natrilam 10 Tablet can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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AMLODIPINE-10MG+INDAPAMIDE-1.5MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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AMLODIPINE-10MG+INDAPAMIDE-1.5MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit, Grapefruit Juice

How to manage the interaction:
Consumption of grapefruit and grapefruit juice along with Indapamide and Amlodipine the levels of Indapamide and Amlodipine in your bloodstream may drop. Avoid consuming a lot of grapefruit and grapefruit juice when using Natrilam 10 Tablet, instead, take it with water. As a result, your body will absorb the drug more easily.

Diet & Lifestyle Advise

  • Keep your weight under control with a body mass index (BMI) between 19.5 and 24.9.
  • Quit smoking to lower the risk of heart disease. 
  • Avoid chronic stress, as it can raise your blood pressure. Try to enjoy and spend time with your loved ones to cope with stress.
  • Monitor your blood pressure daily, and if you notice any fluctuations frequently, please get in touch with your doctor immediately.
  • Try including heart-healthy omega-3 fatty acid-containing foods in your daily diet. You can also use low-fat cooking oils like olive oil, soybean oil, canola oil, and coconut oil that help in lowering your elevated blood pressure.

Habit Forming

No

Therapeutic Class

MISCELLANEOUS

Natrilam 10 Tablet 10's Substitute

Substitutes safety advice
  • Natrilam Tablet 10's

    by Others

    14.49per tablet

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • SILDENAFIL
  • OXYCODONE
  • PREDNISONE
  • CLONAZEPAM
  • ESOMEPRAZOLE
  • INSULIN GLARGINE
  • METFORMIN
  • CHOLECALCIFEROL
  • RISPERIDONE
  • DULOXETINE
  • DIGOXIN
  • AMIODARONE
  • LISINOPRIL
  • CANDESARTAN
  • LITHIUM
  • NAPROXEN
  • AMISULPRIDE
  • IBUPROFEN
  • PIMOZIDE
  • ALPRAZOLAM
  • CLONIDINE
  • BACLOFEN
  • LEVODOPA
  • METOPROLOL
  • CHLORTHALIDONE
  • HYDROCHLOROTHIAZIDE
  • FUROSEMIDE
  • TORSEMIDE
  • RAMIPRIL

Special Advise

  • Monitor your blood pressure regularly and seek medical advice if you notice any drastic fluctuations.
  • Let your doctor know if you are advised for any blood examinations as diuretics like Indapamide can cause changes in the laboratory parameters like low potassium levels in the blood, low sodium in the blood, low blood pressure, increase in uric acid, increase in blood glucose levels in diabetic patients, increase in calcium levels in the blood, and increase in the liver enzyme levels. 
  • Let your anaesthetist or medical staff know that you are taking Natrilam 10 Tablet 10's since Natrilam 10 Tablet 10's can lower blood pressure levels when certain anaesthetic medications are given during any operation or surgery.
  • Athletes should be aware that Indapamide in Natrilam 10 Tablet 10's gives a positive reaction in doping tests.

Disease/Condition Glossary

Hypertension: When blood pressure is excessively high, it becomes a chronic problem. Blood pressure is determined by how much blood the heart pumps and how much resistance the arteries provide to the flow of blood. Blood pressure rises, and arteries constrict as the heart pumps more blood. If not treated, uncontrolled blood pressure can cause major cardiac conditions, including heart attack and stroke. Kidney failure and brain damage are two more effects of high blood pressure. Headache, bleeding from the nose, nausea, and chest discomfort are a few signs of hypertension.

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