Nazipam Plus 0.25 mg Tablet 10's

Written By Santoshini Reddy G , M Pharmacy

Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

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MRP ₹45

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Whats That

About Nazipam Plus 0.25 mg Tablet

Nazipam Plus 0.25 mg Tablet belongs to the group of medicines called anxiolytics used to treat anxiety. Besides this, Nazipam Plus 0.25 mg Tablet is also used to treat high blood pressure, panic disorder, seizure disorder, fast heartbeat, and migraine. Anxiety is a mental health disorder characterised by feelings of anxiety, worry or fear that are strong enough to interfere with one’s daily activities. Symptoms of anxiety include rapid breathing, increased heart rate, restlessness, trouble concentrating, and difficulty falling asleep.

Nazipam Plus 0.25 mg Tablet is a combination of two drugs: Clonazepam (benzodiazepine) and Propranolol (beta-blocker). Clonazepam works by increasing the action of a chemical messenger called GABA; this helps suppress the excessive and abnormal activity of the nerve cells in the brain. Propranolol blocks certain chemical messengers' action on the heart and blood vessels; this helps reduce heart rate and blood pressure.

You are advised to take Nazipam Plus 0.25 mg Tablet for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side-effects such as dry mouth, slow heart rate, depression, fatigue, nightmares, sleep disturbances, memory impairment, and confusion. You are advised to talk to your doctor if you experience these side-effects persistently.

Please do not stop taking Nazipam Plus 0.25 mg Tablet on your own as it might cause withdrawal symptoms. Consult your doctor if you are pregnant or breastfeeding. Nazipam Plus 0.25 mg Tablet may cause dizziness and sleepiness; do not drive or handle machinery unless you are alert. Avoid consumption of alcohol while taking Nazipam Plus 0.25 mg Tablet as it may cause increased dizziness. Nazipam Plus 0.25 mg Tablet is not recommended for children as safety and effectiveness were not established. Keep your doctor informed about all the medicines you are taking, including prescription, non-prescription medicines and herbal supplements.

Uses of Nazipam Plus 0.25 mg Tablet

Anxiety

Directions for Use

Take Nazipam Plus 0.25 mg Tablet on an empty stomach. Swallow Nazipam Plus 0.25 mg Tablet as a whole with a glass of water; do not chew or crush it.

Medicinal Benefits

Nazipam Plus 0.25 mg Tablet is a combination of two drugs, namely: Clonazepam and Propranolol. Nazipam Plus 0.25 mg Tablet is used to treat anxiety. Clonazepam is a benzodiazepine that increases the action of a chemical messenger called GABA; this helps suppress the excessive and abnormal activity of the nerve cells in the brain. Propranolol is a beta-blocker that works by blocking certain chemical messengers' action on the heart and blood vessels; this helps reduce heart rate and blood pressure.

Storage

Keep Nazipam Plus 0.25 mg Tablet out of reach and sight of children.

Side effects of Nazipam Plus 0.25 mg Tablet

Drowsiness

Get enough sleep. Maintain a regular sleep cycle.
Eat a healthy diet and exercise regularly.
Manage stress with yoga or meditation.
Limit alcohol and caffeine.
Avoid driving or operating machinery unless you are alert.

Behavioural Disturbances

Approach calmly, use a non-threatening tone, actively listen, validate concerns, and provide clear instructions.
Practice environmental changes like adjusting lighting, noise levels, and providing a safe space.
Recognizing and praising desired behaviors.
Maintaining consistent schedules for daily activities.
Try to engage in calming activities to redirect focus.

Common Cold

Here are the steps to manage the medication-triggered Upper respiratory tract infection:

Inform your doctor about the symptoms you're experiencing due to medication.
Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
Stay hydrated by drinking plenty of fluids to help loosen and clear mucus from your nose, throat, and airways.
Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.

Uncoordinated Muscle Movements

Uncoordinated muscle movements need immediate medical attention.
Observe your movements and try to understand and control the particular movement.
Regularly do strengthening exercises to improve blood flow throughout the body and avoid involuntary movements.
Implement massage techniques to enhance blood flow to organs.
Take a balanced diet and quit smoking.
Practice yoga and meditation to improve thought processes and reduce uncontrolled and involuntary movements.

Cough Producing Mucus

Managing Medication-Triggered Productive cough (wet cough): A Step-by-Step Guide:

If you experience a persistent cough after taking medication, consult your doctor to determine the best course of action.
Your doctor will assess and adjust your medication regimen if necessary to minimize the cough.
Your doctor may recommend cough medications, such as expectorants, to help loosen and clear mucus.
Stay hydrated by drinking plenty of fluids, and consider a soothing lifestyle, such as a warm, humid environment, avoiding irritants like smoke and dust, and getting plenty of rest.
If your cough persists or worsens, follow up with your doctor for further evaluation and treatment.

Anxiety

Managing Medication-Triggered Anxiety: A Comprehensive Approach:

Inform your doctor about your anxiety symptoms so that you doctor may explore potential drug interactions and alter your treatment plan.
Work with your doctor to adjust your medication regimen or dosage to minimize anxiety symptoms.
Reduce anxiety symptoms by practicing relaxation techniques like meditation, deep breathing, or yoga.
Regular self-care activities, such as exercise, healthy food, and adequate sleep, can assist control anxiety.
Surround yourself with a supportive network of friends, family, or a support group to help manage anxiety and stay motivated.
Regularly track anxiety symptoms and report any changes to your doctor to ensure your treatment plan is effective and adjusted as needed.

Dry Mouth

Here are the steps to Dry Mouth (xerostomia) caused by medication:

Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.

Drug Warnings

Do not take Nazipam Plus 0.25 mg Tablet if you are allergic to any of its contents; if you have breathing or lung problems, severe liver problems, and myasthenia gravis (muscle problems). Inform your doctor if you have depression, porphyria, kidney, or liver disorder or are elderly. Nazipam Plus 0.25 mg Tablet may be habit-forming, so inform your doctor if you have a history of drug addiction or abuse. Keep your doctor informed about all the medicines you are taking, including prescription, non-prescription medicines and herbal supplements. Please do not stop taking Nazipam Plus 0.25 mg Tablet on your own as it might cause withdrawal symptoms. Nazipam Plus 0.25 mg Tablet may cause dizziness and sleepiness; do not drive or handle machinery unless you are alert. Avoid consumption of alcohol while taking Nazipam Plus 0.25 mg Tablet as it may cause increased dizziness. Nazipam Plus 0.25 mg Tablet is not recommended for children as safety and effectiveness were not established. Talk to your doctor immediately if you experience suicidal thoughts such as killing or harming yourself.

Drug-Drug Interactions

ClonazepamSodium oxybate

Critical

PropranololThioridazine

Critical

Drug-Drug Interactions

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ClonazepamSodium oxybate

Critical

How does the drug interact with Nazipam Plus 0.25 mg Tablet:
Taking Nazipam Plus 0.25 mg Tablet with Sodium oxybate can enhance the sedative effects on the central nervous system.

How to manage the interaction:
Taking Nazipam Plus 0.25 mg Tablet and Tramadol together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience any symptoms such as dizziness, drowsiness, difficulty concentrating, numbness and tingling of extremities, or hypersensitivity to light and noise, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.

PropranololThioridazine

Critical

How does the drug interact with Nazipam Plus 0.25 mg Tablet:
Coadministration of thioridazine with Nazipam Plus 0.25 mg Tablet may increase the blood levels of thioridazine and cause an irregular heart rhythm that may be serious.

How to manage the interaction:
Although there is an interaction between Nazipam Plus 0.25 mg Tablet and thioridazine, they can be taken together if prescribed by a doctor. However, if you experience sudden dizziness, lightheadedness, fainting, and shortness of breath contact your doctor immediately. Do not stop using any medications without first talking to your doctor.

ClonazepamBuprenorphine

Severe

How does the drug interact with Nazipam Plus 0.25 mg Tablet:
When Buprenorphine is used with Nazipam Plus 0.25 mg Tablet, it may lead to significant adverse effects such as respiratory difficulties.

How to manage the interaction:
Co-administration of Buprenorphine alongside Nazipam Plus 0.25 mg Tablet can result in an interaction, it can be taken if a doctor has advised it. Do not exceed the doses, frequency, or duration of usage advised by a doctor. You should avoid driving or operating hazardous machinery until you know how these drugs affect you. Do not discontinue any medications without consulting a doctor.

ClonazepamTapentadol

Severe

How does the drug interact with Nazipam Plus 0.25 mg Tablet:
Co-administration of Tapentadol together with Nazipam Plus 0.25 mg Tablet can increase the risk or severity of side effects like decreased breathing rate, irregular heart rhythms, or problems with movement and memory.

How to manage the interaction:
Taking Nazipam Plus 0.25 mg Tablet with Tapentadol can result in an interaction, it can be taken if your doctor has advised it. Contact a doctor immediately if you experience signs such as drowsiness, lightheadedness, palpitations, confusion, severe weakness, or difficulty breathing. Do not discontinue any medications without consulting a doctor.

ClonazepamKetamine

Severe

How does the drug interact with Nazipam Plus 0.25 mg Tablet:
When Nazipam Plus 0.25 mg Tablet and Ketamine are taken together, may increase the risk or severity of side effects.

How to manage the interaction:
There may be a possibility of interaction between Ketamine and Nazipam Plus 0.25 mg Tablet, but it can be taken if prescribed by a doctor. If you start feeling dizzy, tired, confused, have trouble focusing, feel very sleepy, or have trouble breathing, make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.

ClonazepamButorphanol

Severe

How does the drug interact with Nazipam Plus 0.25 mg Tablet:
Co-administration of Butorphanol with Nazipam Plus 0.25 mg Tablet can increase the risk of side effects.

How to manage the interaction:
Although taking Nazipam Plus 0.25 mg Tablet and Butorphanol together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you notice any symptoms like feeling dizzy, having trouble breathing, or feeling very tired, make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.

ClonazepamCodeine

Severe

How does the drug interact with Nazipam Plus 0.25 mg Tablet:
Co-administration of Nazipam Plus 0.25 mg Tablet with Codeine may cause serious side effects like respiratory depression.

How to manage the interaction:
Consult a doctor if you are taking Nazipam Plus 0.25 mg Tablet with Codeine. Until you know how the medicines affect you, avoid driving or operating hazardous machinery as these medications may cause drowsiness, dizziness, difficulty concentrating, and impairment in judgment, reaction speed, and motor coordination. Do not exceed the dose and duration prescribed by your doctor. Do not stop using any medications without talking to a doctor.

ClonazepamHydromorphone

Severe

How does the drug interact with Nazipam Plus 0.25 mg Tablet:
Co-administration of Nazipam Plus 0.25 mg Tablet with Hydromorphone may cause serious side effects like respiratory depression (a condition in which fluid builds up in the lungs).

How to manage the interaction:
Consult the doctor if you are taking Nazipam Plus 0.25 mg Tablet with Hydromorphone. Until you know how these medicines affect you, avoid driving or operating hazardous machinery as these medications may cause dizziness, drowsiness, difficulty concentrating, and impairment in judgment, reaction speed, and motor coordination. Do not exceed the dose and duration prescribed by a doctor. Do not discontinue the medication without consulting a doctor.

ClonazepamNalbuphine

Severe

How does the drug interact with Nazipam Plus 0.25 mg Tablet:
Co-administration of Nalbuphine with Nazipam Plus 0.25 mg Tablet can make the side effects worse.

How to manage the interaction:
Although there is a possible interaction between Nazipam Plus 0.25 mg Tablet and Nalbuphine, you can take these medicines together if prescribed by a doctor. If you notice any symptoms like feeling dizzy, having trouble breathing, or feeling very tired, make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.

ClonazepamPentazocine

Severe

How does the drug interact with Nazipam Plus 0.25 mg Tablet:
Co-administration of Pentazocine with Nazipam Plus 0.25 mg Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Nazipam Plus 0.25 mg Tablet with Pentazocine together can possibly result in an interaction, but it can be taken if a doctor has advised it. They can recommend different options that won't cause any problems. If you notice any symptoms like feeling dizzy, having trouble breathing, or feeling very tired, make sure to call a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Attend therapy sessions regularly.
Eat a healthy diet.
Try to stay active and exercise regularly.
Take ample rest. Get enough sleep.
Meditate regularly as it helps in easing the anxiety.
Avoid smoking, caffeine, and alcohol consumption.
Foods and drinks like salmon, chamomile, turmeric, dark chocolate, green tea, and yoghurt may help with anxiety.

Side Effects of Nazipam Plus 0.25 mg Tablet

Dry mouth
Slow heart rate
Depression
Fatigue
Nightmares
Sleep disturbances
Memory impairment
Confusion

Habit Forming

Yes

Therapeutic Class

ANXIOLYTICS

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Author Details

Written By

Santoshini Reddy G

M Pharmacy

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 8, 2025 | 9:35 AM IST

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Drug-Diseases Interactions

No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

How does Nazipam Plus 0.25 mg Tablet work?

Nazipam Plus 0.25 mg Tablet contains Clonazepam and Propranolol. Clonazepam works by increasing the action of a chemical messenger called GABA; this helps suppress the excessive and abnormal activity of the nerve cells in the brain. Propranolol blocks certain chemical messengers' action on the heart and blood vessels; this helps reduce heart rate and blood pressure.

Can I stop taking Nazipam Plus 0.25 mg Tablet on my own?

Do not stop taking Nazipam Plus 0.25 mg Tablet on your own as it might increase the seizure frequency, chest pain and heart attack. Stopping it suddenly may cause withdrawal symptoms such as nausea, anxiety, muscle pain, and flu-like symptoms. Consult your doctor if you experience any difficulty while taking Nazipam Plus 0.25 mg Tablet ; the doctor may gradually reduce the dose.

How to cope with dry mouth?

Dry mouth could be a side-effect of Nazipam Plus 0.25 mg Tablet . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.

Is Nazipam Plus 0.25 mg Tablet habit-forming?

Nazipam Plus 0.25 mg Tablet has high habit-forming potential. Therefore, take Nazipam Plus 0.25 mg Tablet only in the dose and duration prescribed by the doctor.

Does Nazipam Plus 0.25 mg Tablet cause changes in weight?

Nazipam Plus 0.25 mg Tablet might cause weight gain or weight loss, depending on person to person. Eat a balanced diet and exercise regularly to prevent weight gain; if you experience weight loss, increase your diet portions.

Does Nazipam Plus 0.25 mg Tablet cause postural hypotension (sudden lowering in blood pressure leading to dizziness on standing)?

Nazipam Plus 0.25 mg Tablet may cause postural hypotension. Postural hypotension is a sudden lowering in blood pressure leading to dizziness on standing. To prevent this, do not try to stand up suddenly or start walking; instead, lie down and get up slowly only when you feel better.

Drug-Drug Interactions Checker List

ALUMINIUM HYDROXIDE
BEPRIDIL
ATROPINE
CHLORPROMAZINE
CARBAMAZEPINE

Special Advise

Nazipam Plus 0.25 mg Tablet might cause suicidal thoughts. Consult your doctor immediately if you experience unusual mood changes, depression or suicidal thoughts such as killing or harming yourself.
Regularly monitor your blood pressure levels while taking Nazipam Plus 0.25 mg Tablet .

Disease/Condition Glossary

Anxiety: It is a mental health disorder characterised by feelings of anxiety, worry or fear that are strong enough to interfere with one’s daily activities. Anxiety is the body’s natural response to stress in which the feeling of fear may be intense and debilitating. It is the most common form of emotional disorder and can affect anyone at any age. Anxiety may cause a panic attacks, obsessive-compulsive disorder, and post-traumatic stress disorder. The exact cause of anxiety is unknown, but it might be due to genetic or environmental factors. Symptoms of anxiety include rapid breathing, increased heart rate, restlessness, trouble concentrating, and difficulty falling asleep.