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Written By Divya L , PharmaD
Reviewed By Veda Maddala , M Pharmacy
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Consume Type

TOPICAL

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About Neosporin Skin Ointment 30 gm

Neosporin Skin Ointment 30 gm is a dermatological medication that belongs to the class of 'antibiotics' and is primarily used to treat bacterial skin infections. Neosporin Skin Ointment 30 gm is used as a first aid antibiotic to prevent infections in minor cuts, scrapes, or burns on the skin. Bacterial skin infection occurs when bacteria penetrate through hair follicles or the broken skin and cause infection.

Neosporin Skin Ointment 30 gm is composed of three antibiotic medicines: Bacitracin, Neomycin, and Polymyxin B. Bacitracin is a bacteriostatic medicine that works by inhibiting the bacterial cell wall synthesis. Neomycin prevents the synthesis of essential proteins required by bacteria to carry out vital functions. Polymyxin B destroys the bacterial membranes by binding to the phospholipids on cell membranes of gram-negative bacteria. This process of binding causes the loss of essential metabolites in bacteria. Together, Neosporin Skin Ointment 30 gm treats bacterial skin infections.

Your doctor will advise the appropriate dose that suits your infection. Common side effects of Neosporin Skin Ointment 30 gm include itching, skin irritation, rash, redness, and swelling at the application site. These side effects may not occur in every patient using this medication and differ individually. If the side effects persist longer or worsen, please seek a doctor's advice.

Inform your doctor if you are sensitive to Neosporin Skin Ointment 30 gm or other medications. Do not apply Neosporin Skin Ointment 30 gm on deep puncture wounds, serious burns, deep cuts or an animal bite. Let your doctor know if you have viral or fungal skin infections, chronic ear infections, and ruptured ear drum before using Neosporin Skin Ointment 30 gm. Pregnant and breastfeeding women should consult their doctor before starting Neosporin Skin Ointment 30 gm. 

Uses of Neosporin Skin Ointment 30 gm

Bacterial skin infections. 

Directions for Use

Cream/Ointment: Apply a thin layer with clean and dry hands on the skin's affected areas. You can also apply it with a piece of clean cotton wool or gauze swab. Gently rub the medicine into the skin until it is disappeared. Wash your hands before and after applying Neosporin Skin Ointment 30 gm on the affected areas unless the treatment is for hands. Dusting powder: Dust the powder on the skin's affected areas and pat it lightly on the skin.

Medicinal Benefits

Neosporin Skin Ointment 30 gm is composed of three antibiotic medicines, namely Bacitracin, Neomycin, and Polymyxin B. Bacitracin is a bacteriostatic medicine (that stops the growth or reproduction of bacteria). It works by inhibiting bacterial cell wall synthesis. Neomycin is an aminoglycoside antibiotic and prevents the synthesis of essential proteins required by bacteria to carry out vital functions. Polymyxin B, an antibiotic, destroys the bacterial membrane by binding to the phospholipids on the cell membranes of gram-negative bacteria. This process of binding causes the loss of essential metabolites in bacteria. Together, Neosporin Skin Ointment 30 gm treats bacterial skin infections.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Neosporin Skin Ointment 30 gm

  • Itching
  • Skin irritation
  • Rash
  • Redness
  • Swelling at the application site 

Drug Warnings

Let your doctor know if you have viral or fungal skin infections, chronic ear infections, and ruptured ear drum before using Neosporin Skin Ointment 30 gm. Avoid applying Neosporin Skin Ointment 30 gm on sunburns, lesions, blisters and open wounds. Do not wash the treated areas for a minimum of 3 hours after you apply Neosporin Skin Ointment 30 gm. Let your doctor know if you plan to become pregnant, are already pregnant or are a lactating mother before using Neosporin Skin Ointment 30 gm. Use Neosporin Skin Ointment 30 gm in children more than 2 years only if a doctor recommends it.

Drug-Drug Interactions

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BacitracinPolymyxin b
Severe
BacitracinCarboplatin
Severe

Drug-Drug Interactions

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BacitracinPolymyxin b
Severe
How does the drug interact with Neosporin Skin Ointment 30 gm:
Taking Polymyxin b and Neosporin Skin Ointment 30 gm together can increase the risk of kidney and inner ear damage

How to manage the interaction:
Although taking Polymyxin b and Neosporin Skin Ointment 30 gm together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience ringing in the ears, hearing loss, vertigo, nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, swelling, difficulty breathing, bone pain, muscle pain, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
BacitracinCarboplatin
Severe
How does the drug interact with Neosporin Skin Ointment 30 gm:
Taking carboplatin and Neosporin Skin Ointment 30 gm can increase the risk of nephrotoxicity(kidney damage).

How to manage the interaction:
Co-administration of carboplatin and Neosporin Skin Ointment 30 gm can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any unusual symptoms consult the doctor. Do not discontinue any medications without a doctor's advice.
BacitracinClindamycin
Severe
How does the drug interact with Neosporin Skin Ointment 30 gm:
Co-administration of Clindamycin with Neosporin Skin Ointment 30 gm may increase the risk of kidney and/or nerve damage.

How to manage the interaction:
Although there is a possible interaction, clindamycin can be taken with Neosporin Skin Ointment 30 gm if prescribed by the doctor. Consult the prescriber if you experience signs and symptoms of kidney damage such as sudden weight gain or weight loss, nausea, vomiting, fluid retention, loss of appetite, increased or decreased urination, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Let your doctor know if you develop seizures; hearing problems; or numbness, burning or tingling in your hands and feet. If you develop diarrhoea or vomiting during treatment with these medications, drink plenty of fluids to prevent dehydration, as dehydration may harm the kidney.
BacitracinSirolimus
Severe
How does the drug interact with Neosporin Skin Ointment 30 gm:
Co-administration of Neosporin Skin Ointment 30 gm and Sirolimus can increase the risk or severity of Kidney problems.

How to manage the interaction:
Co-administration of Sirolimus with Neosporin Skin Ointment 30 gm can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
BacitracinHydroxycarbamide
Severe
How does the drug interact with Neosporin Skin Ointment 30 gm:
Hydroxycarbamide when used in conjunction with Neosporin Skin Ointment 30 gm may raise the risk of severe infections.

How to manage the interaction:
There may be a possibility of interaction between hydroxycarbamide with Neosporin Skin Ointment 30 gm, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhoea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
BacitracinDeferasirox
Severe
How does the drug interact with Neosporin Skin Ointment 30 gm:
Deferasirox may cause kidney problems and combining it with Neosporin Skin Ointment 30 gm may increase that risk.

How to manage the interaction:
Although taking Neosporin Skin Ointment 30 gm and Deferasirox together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, or irregular heart rhythm, seek immediate medical attention. Drink plenty of water if you experience diarrhoea or vomiting while taking these medications, as dehydration can potentially affect the kidneys. Do not discontinue any medications without a doctor's advice.
BacitracinGentamicin
Severe
How does the drug interact with Neosporin Skin Ointment 30 gm:
Taking gentamicin with Neosporin Skin Ointment 30 gm may increase the risk of serious side effects such as respiratory depression, kidney problems, and hearing loss.

How to manage the interaction:
Although there is a possible interaction, gentamicin can be taken with Neosporin Skin Ointment 30 gm if prescribed by the doctor. Consult the prescriber if you experience hearing loss, ringing in the ears, vertigo, difficulty breathing, (or) signs and symptoms of kidney damage such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm.
BacitracinAmikacin
Severe
How does the drug interact with Neosporin Skin Ointment 30 gm:
Coadministration of Amikacin with Neosporin Skin Ointment 30 gm can increase the risk of developing side effects like hearing loss, difficulty breathing, or kidney problems.

How to manage the interaction:
Although taking amikacin and Neosporin Skin Ointment 30 gm together can result in an interaction, it can be taken if a doctor has prescribed it. Consult a doctor if you experience ringing in the ears, difficulty breathing, vomiting, increased or decreased urination, swelling, muscle cramps, dizziness, or palpitations. Do not stop using any medications without talking to a doctor.
BacitracinHuman immunoglobulin
Severe
How does the drug interact with Neosporin Skin Ointment 30 gm:
Taking Human immunoglobulin with Neosporin Skin Ointment 30 gm, may raise the risk of kidney problems.

How to manage the interaction:
Taking Human immunoglobulin with Neosporin Skin Ointment 30 gm together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
BacitracinEverolimus
Severe
How does the drug interact with Neosporin Skin Ointment 30 gm:
Everolimus can cause kidney issues, and taking it with Neosporin Skin Ointment 30 gm, can enhance the risk.

How to manage the interaction:
Although taking Neosporin Skin Ointment 30 gm and Everolimus together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Use mild soap while taking baths and prefer warm baths.
  • Always wear loose-fitting clothes to avoid further sweat and spreading skin infection.
  • Do not scratch the affected skin area.
  • Avoid sharing towels, combs, bedsheets, shoes or socks with others.
  • Wash your bed sheets and towels regularly.
  • Avoid or limit the intake of alcohol and caffeine.
  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS - TOPICAL

Neosporin Skin Ointment 30 gm Substitute

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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • AMIKACIN
  • GENTAMICIN
  • TOBRAMYCIN

Special Advise

  • It is advised to contact your doctor if the infection symptoms persist or worsen after two weeks of treatment.
  • Avoid contact of Neosporin Skin Ointment 30 gm with nose, mouth or eyes. If Neosporin Skin Ointment 30 gm accidentally comes in contact with these areas, rinse with water thoroughly. 

Disease/Condition Glossary

Bacterial skin infection: Bacterial skin infection occurs when bacteria penetrate through hair follicles or the broken skin breaks and cause infection. Symptoms include redness, pain, and tenderness of the skin, minor bumps or boils, rashes, blisters, cracked/dry skin, swelling, stinging or burning sensation, pus formation, and itching. Bacterial skin infections are generally mild and can be treated using topical antibiotics. Sometimes, for a severe infection, an oral antibiotic may be required. Common bacterial infections include cellulitis (red and swollen skin), erysipelas (large patches on the skin), impetigo (red sores on the face), folliculitis (inflammation of hair follicles), and carbuncles (pus-filled bumps).

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