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Written By ,
Reviewed By Sureshvarma D , MPharma

About Nevilast 40 mg Tablet 10's

Nevilast 40 mg Tablet 10's belongs to the class of medications called ‘antiretroviral agents’ used in the treatment of HIV infection. HIV is a virus that attacks the immune cells of the body leading to decreased immunity. It spreads through body fluids such as semen, vaginal fluid, and blood. Symptoms include fever, chills, rash, night sweats, muscle aches, tiredness and sore throat that usually last for days to several weeks.

Nevilast 40 mg Tablet 10's is a combination of three medicines: Stavudine, lamivudine and nevirapine. They work by inhibiting the reverse transcriptase enzyme from working, which is required by the HIV-infected cells to make new viruses. This effect helps to inhibit viral replication.

You should take this medicine exactly as prescribed by the doctor. Nevilast 40 mg Tablet 10's may cause side effects such as headache, insomnia (difficulty in sleeping), nausea, diarrhea, dry mouth, fever, rash, and peripheral neuropathy (tingling and numbness of feet and hands). Inform your doctor if any of these side effects persist or get worse.

It is not recommended to take Nevilast 40 mg Tablet 10's if you are allergic to any contents of it. Before taking Nevilast 40 mg Tablet 10's, inform your doctor if you have any liver disease, hepatitis B or C (liver infections), a history of mental illness, seriously overweight and have kidney disease. Inform your doctor if you are pregnant or breastfeeding. Nevilast 40 mg Tablet 10's should be used with caution in children and elderly patients. Alcohol consumption may increase the risk of side effects. Nevilast 40 mg Tablet 10's may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy.

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Non returnable*
COD available

Online payment accepted

Consume Type

ORAL

Return Policy

Not Returnable

for this medicine

Uses of Nevilast 40 mg Tablet 10's

HIV infection

Medicinal Benefits

Nevilast 40 mg Tablet 10's belongs to the group of medicines called antiretroviral therapy (ART). Nevilast 40 mg Tablet 10's contains stavudine, lamivudine, and nevirapine. Nevilast 40 mg Tablet 10's work by inhibiting the reverse transcriptase enzyme from working, which is required by the HIV-infected cells to make new viruses. Thereby preventing viral replication and controlling the infection. It helps in improving the quality of life of a patient with HIV.

Side Effects of Nevilast 40 mg Tablet 10's

  • Headache
  • Tiredness
  • Insomnia (difficulty in sleeping)
  • Diarrhea
  • Dryness in mouth
  • Fever
  • Peripheral neuropathy (tingling and numbness of feet and hand)

Directions for Use

Take Nevilast 40 mg Tablet 10's with food or after a meal as advised by the doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Inform your doctor if you develop persistent diarrhea or vomiting, as it may affect the effectiveness of Nevilast 40 mg Tablet 10's. Nevilast 40 mg Tablet 10's may cause pancreatitis (inflammation of the pancreas), so inform your doctor if you develop symptoms such as nausea (feeling sick), vomiting or stomach pain. Nevilast 40 mg Tablet 10's may lead to opportunistic infections (infections that occur frequently or severely in patients with weak immune systems), so inform your doctor immediately if you experience symptoms of infection such as muscle weakness, weakness beginning in the hands and feet that progress towards the trunk, palpitations (pounding heartbeat) and tremors. Nevilast 40 mg Tablet 10's may destroy bone leading to symptoms such as joint stiffness or pain. It may also cause muscle pain, tenderness, or weakness. Speak with your doctor about the precautions to follow to avoid infecting other people as one can still pass on HIV while on this medicine, although the risk is somewhat lowered by antiretroviral therapy, it can spread through sexual contact with a person who already has the infection or by transfer of infected blood. Nevilast 40 mg Tablet 10's does not cure HIV infection. Nevilast 40 mg Tablet 10's can make hormonal contraceptives less effective or less likely to work. So, use other effective methods for contraception, including a barrier form (cervical cap, condom, diaphragm, or contraceptive sponge) to prevent pregnancy as advised by your doctor. Do not breastfeed while taking this medicine. Nevilast 40 mg Tablet 10's is not recommended in pregnancy as could harm the unborn baby or cause birth defects. You may need frequent medical tests while on Nevilast 40 mg Tablet 10's.

Therapeutic Class

ANTIRETROVIRAL AGENTS

Drug-Drug Interactions

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NevirapineAtazanavir
Critical
NevirapineRanolazine
Critical

Drug-Drug Interactions

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NevirapineAtazanavir
Critical
How does the drug interact with Nevilast 40 mg Tablet 10's:
When Atazanavir is taken with Nevilast 40 mg Tablet 10's, it can reduce the levels and side effects of atazanavir & increase the blood levels and effects of Nevilast 40 mg Tablet 10's.

How to manage the interaction:
Taking Nevilast 40 mg Tablet 10's with Atazanavir is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience a rash on any parts of your body, loss of appetite, nausea, vomiting, jaundice (yellowing of the skin and/or eyes), dark-coloured urine, pale-coloured stools, or pain or ache in the right abdominal area below your ribs, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
NevirapineRanolazine
Critical
How does the drug interact with Nevilast 40 mg Tablet 10's:
Co-administration of Nevilast 40 mg Tablet 10's with Ranolazine may significantly reduce the blood levels of Ranolazine. This can lead to low treatment outcomes.

How to manage the interaction:
Taking Nevilast 40 mg Tablet 10's with Ranolazine is generally avoided as it can lead to an interaction, they can be taken together if advised by a doctor. However, contact a doctor if you experience any symptoms. Do not stop taking any medications without consulting a doctor.
LamivudineEmtricitabine
Critical
How does the drug interact with Nevilast 40 mg Tablet 10's:
Combining these two medications may reduce overall effectiveness due to potential antagonistic effects (opposite actions).

How to manage the interaction:
Taking Emtricitabine with Nevilast 40 mg Tablet 10's is not recommended, but it can be taken if your doctor prescribes it. Contact your doctor if your symptoms do not improve. Do not stop taking any medication without consulting your doctor.
NevirapineOlaparib
Severe
How does the drug interact with Nevilast 40 mg Tablet 10's:
When Olaparib is taken with Nevilast 40 mg Tablet 10's may reduce the blood levels of Olaparib. This can lead to low treatment outcomes.

How to manage the interaction:
There may be a possibility of interaction between Nevilast 40 mg Tablet 10's and Olaparib, but it can be taken if prescribed by a doctor. Do not discontinue any medications without first consulting a doctor.
NevirapineDolutegravir
Severe
How does the drug interact with Nevilast 40 mg Tablet 10's:
Taking dolutegravir with Nevilast 40 mg Tablet 10's can reduce the effectiveness of dolutegravir.

How to manage the interaction:
Although taking Dolutegravir and Nevilast 40 mg Tablet 10's together can possibly result in an interaction, they can be taken together if prescribed by your doctor. Do not discontinue using any medications without consulting a doctor.
NevirapineBrigatinib
Severe
How does the drug interact with Nevilast 40 mg Tablet 10's:
When Brigatinib is taken with Nevilast 40 mg Tablet 10's may reduce the blood levels of Brigatinib. This can lead to low treatment outcomes.

How to manage the interaction:
Taking Nevilast 40 mg Tablet 10's with Brigatinib together can possibly result in an interaction, but it can be taken if your doctor has advised it.Do not stop using any medications without a doctor's advice.
NevirapineCaspofungin
Severe
How does the drug interact with Nevilast 40 mg Tablet 10's:
Using Nevilast 40 mg Tablet 10's together with caspofungin may cause caspofungin to be less effective.

How to manage the interaction:
Although there is a possible interaction between Caspofungin and Nevilast 40 mg Tablet 10's, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
NevirapineSimeprevir
Severe
How does the drug interact with Nevilast 40 mg Tablet 10's:
When Simeprevir is taken with Nevilast 40 mg Tablet 10's may reduce the blood levels of Simeprevir.

How to manage the interaction:
Although taking Nevilast 40 mg Tablet 10's and Simeprevir together can evidently cause an interaction, it can be taken if your doctor has suggested it. Do not stop using any medications without a doctor's advice.
NevirapineAmiodarone
Severe
How does the drug interact with Nevilast 40 mg Tablet 10's:
Coadministration of Nevilast 40 mg Tablet 10's with Amiodarone may decrease the effects of amiodarone. This can lead to low treatment outcomes.

How to manage the interaction:
Taking Amiodarone with Nevilast 40 mg Tablet 10's together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or irregular heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
NevirapineLomitapide
Severe
How does the drug interact with Nevilast 40 mg Tablet 10's:
Coadministration of Nevilast 40 mg Tablet 10's and Lomitapide may increase the risk or severity of liver problems.

How to manage the interaction:
Although taking Nevilast 40 mg Tablet 10's and Lomitapide together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark urine, pale stools, and/or yellowing of the skin or eyes call a doctor right away. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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STAVUDINE-40MG+NEVIRAPINE-200MG+LAMIVUDINE-150MGHigh fat foods
Mild

Drug-Food Interactions

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STAVUDINE-40MG+NEVIRAPINE-200MG+LAMIVUDINE-150MGHigh fat foods
Mild
Common Foods to Avoid:
Frozen Meals, Cheese, Red Meat, Potato Chips, Hamburgers, Hot Dogs, Ice Cream

How to manage the interaction:
Taking Nevilast 40 mg Tablet 10's with high fatty foods can reduce the effectiveness of Nevilast 40 mg Tablet 10's Avoid taking high-fat food while taking Nevilast 40 mg Tablet 10's, as this can lead to interaction.

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • HYDROXYUREA
  • WARFARIN
  • BACTRIM

Diet & Lifestyle Advise

  • Eat a healthy and balanced diet. Eat vitamin and nutrient-rich food such as dark green, yellow, orange and red vegetables, and fruit as it helps to boost your immune system. Option for lean protein and whole grains.
  • Avoid eating raw meat and eggs. Consume properly boiled and cooked meat, poultry or seafood.
  • Eat bland and low-fat foods and avoid spicy or oily foods if you experience nausea or vomiting.
  • Try to reduce emotional and physical stress by spending time with family or whatever makes you happy.
  • Drink more fluids and avoid alcoholic beverages to prevent dehydration. 
  • Wash your hands properly before and after eating.
  • Make sure you sleep at least 8 hours a day.

Habit Forming

No

Special Advise

  • Nevilast 40 mg Tablet 10's may still develop infections or other illnesses associated with HIV infection or AIDS. So, people taking Nevilast 40 mg Tablet 10's should be carefully monitored throughout the treatment.
  • You can still infect other people while taking Nevilast 40 mg Tablet 10's. So, use necessary precautions to avoid infecting others.
  • Nevilast 40 mg Tablet 10's may cause abnormal liver function tests. So, regular monitoring of liver function is necessary while taking this medicine.

Disease/Condition Glossary

HIV infection: HIV (human immunodeficiency virus) is a virus that attacks the immune system, making the individual susceptible to other infections or illnesses. People with HIV experience flu-like symptoms such as fever, chills, rash, night sweats, muscle aches, tiredness and sore throat. These symptoms usually last for days to several weeks. It spreads through body fluids such as semen, vaginal fluid and blood. If left untreated, this condition can lead to AIDS (Acquired Immunodeficiency Syndrome). It is a life-long condition and there is no definite cure for it.  However, it can be controlled by treating with antiretroviral agents.

Nevilast 40 mg Tablet 10's Substitute

Substitutes safety advice
  • Emtri 40 mg Tablet 30's

    36.30per tablet
  • Triomune 40 Tablet 30's

    20.51per tablet
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