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Written By ,
Reviewed By Sureshvarma D , MPharma
Non returnable*
COD available

Online payment accepted

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Manufacturer/Marketer

Cipla Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About Triomune 40 Tablet 30's

Triomune 40 Tablet 30's belongs to the class of medications called ‘antiretroviral agents’ used in the treatment of HIV infection. HIV is a virus that attacks the immune cells of the body leading to decreased immunity. It spreads through body fluids such as semen, vaginal fluid, and blood. Symptoms include fever, chills, rash, night sweats, muscle aches, tiredness and sore throat that usually last for days to several weeks.

Triomune 40 Tablet 30's is a combination of three medicines: Stavudine, lamivudine and nevirapine. They work by inhibiting the reverse transcriptase enzyme from working, which is required by the HIV-infected cells to make new viruses. This effect helps to inhibit viral replication.

You should take this medicine exactly as prescribed by the doctor. Triomune 40 Tablet 30's may cause side effects such as headache, insomnia (difficulty in sleeping), nausea, diarrhea, dry mouth, fever, rash, and peripheral neuropathy (tingling and numbness of feet and hands). Inform your doctor if any of these side effects persist or get worse.

It is not recommended to take Triomune 40 Tablet 30's if you are allergic to any contents of it. Before taking Triomune 40 Tablet 30's, inform your doctor if you have any liver disease, hepatitis B or C (liver infections), a history of mental illness, seriously overweight and have kidney disease. Inform your doctor if you are pregnant or breastfeeding. Triomune 40 Tablet 30's should be used with caution in children and elderly patients. Alcohol consumption may increase the risk of side effects. Triomune 40 Tablet 30's may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy.

Uses of Triomune 40 Tablet 30's

HIV infection

Directions for Use

Take Triomune 40 Tablet 30's with food or after a meal as advised by the doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Medicinal Benefits

Triomune 40 Tablet 30's belongs to the group of medicines called antiretroviral therapy (ART). Triomune 40 Tablet 30's contains stavudine, lamivudine, and nevirapine. Triomune 40 Tablet 30's work by inhibiting the reverse transcriptase enzyme from working, which is required by the HIV-infected cells to make new viruses. Thereby preventing viral replication and controlling the infection. It helps in improving the quality of life of a patient with HIV.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Triomune 40 Tablet 30's

  • Headache
  • Tiredness
  • Insomnia (difficulty in sleeping)
  • Diarrhea
  • Dryness in mouth
  • Fever
  • Peripheral neuropathy (tingling and numbness of feet and hand)

Drug Warnings

Inform your doctor if you develop persistent diarrhea or vomiting, as it may affect the effectiveness of Triomune 40 Tablet 30's. Triomune 40 Tablet 30's may cause pancreatitis (inflammation of the pancreas), so inform your doctor if you develop symptoms such as nausea (feeling sick), vomiting or stomach pain. Triomune 40 Tablet 30's may lead to opportunistic infections (infections that occur frequently or severely in patients with weak immune systems), so inform your doctor immediately if you experience symptoms of infection such as muscle weakness, weakness beginning in the hands and feet that progress towards the trunk, palpitations (pounding heartbeat) and tremors. Triomune 40 Tablet 30's may destroy bone leading to symptoms such as joint stiffness or pain. It may also cause muscle pain, tenderness, or weakness. Speak with your doctor about the precautions to follow to avoid infecting other people as one can still pass on HIV while on this medicine, although the risk is somewhat lowered by antiretroviral therapy, it can spread through sexual contact with a person who already has the infection or by transfer of infected blood. Triomune 40 Tablet 30's does not cure HIV infection. Triomune 40 Tablet 30's can make hormonal contraceptives less effective or less likely to work. So, use other effective methods for contraception, including a barrier form (cervical cap, condom, diaphragm, or contraceptive sponge) to prevent pregnancy as advised by your doctor. Do not breastfeed while taking this medicine. Triomune 40 Tablet 30's is not recommended in pregnancy as could harm the unborn baby or cause birth defects. You may need frequent medical tests while on Triomune 40 Tablet 30's.

Drug-Drug Interactions

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NevirapineAtazanavir
Critical
NevirapineRanolazine
Critical

Drug-Drug Interactions

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NevirapineAtazanavir
Critical
How does the drug interact with Triomune 40 Tablet:
When Atazanavir is taken with Triomune 40 Tablet, it can reduce the levels and side effects of atazanavir & increase the blood levels and effects of Triomune 40 Tablet.

How to manage the interaction:
Taking Triomune 40 Tablet with Atazanavir is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience a rash on any parts of your body, loss of appetite, nausea, vomiting, jaundice (yellowing of the skin and/or eyes), dark-coloured urine, pale-coloured stools, or pain or ache in the right abdominal area below your ribs, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
NevirapineRanolazine
Critical
How does the drug interact with Triomune 40 Tablet:
Co-administration of Triomune 40 Tablet with Ranolazine may significantly reduce the blood levels of Ranolazine. This can lead to low treatment outcomes.

How to manage the interaction:
Taking Triomune 40 Tablet with Ranolazine is generally avoided as it can lead to an interaction, they can be taken together if advised by a doctor. However, contact a doctor if you experience any symptoms. Do not stop taking any medications without consulting a doctor.
LamivudineEmtricitabine
Critical
How does the drug interact with Triomune 40 Tablet:
Combining these two medications may reduce overall effectiveness due to potential antagonistic effects (opposite actions).

How to manage the interaction:
Taking Emtricitabine with Triomune 40 Tablet is not recommended, but it can be taken if your doctor prescribes it. Contact your doctor if your symptoms do not improve. Do not stop taking any medication without consulting your doctor.
NevirapineUlipristal
Severe
How does the drug interact with Triomune 40 Tablet:
When Ulipristal is taken with Triomune 40 Tablet may reduce the blood levels of Ulipristal. This can lead to low treatment outcomes.

How to manage the interaction:
Although taking Triomune 40 Tablet and Ulipristal together can cause an interaction, it can be taken if your doctor has suggested it. Do not discontinue any medications without consulting a doctor.
NevirapinePretomanid
Severe
How does the drug interact with Triomune 40 Tablet:
When Pretomanid is taken with Triomune 40 Tablet may reduce the blood levels of Pretomanid. This can lead to low treatment outcomes.

How to manage the interaction:
Although taking Triomune 40 Tablet and Pretomanid together can cause an interaction, it can be taken if your doctor has suggested it. Do not discontinue any medications without consulting a doctor.
NevirapineButorphanol
Severe
How does the drug interact with Triomune 40 Tablet:
When Butorphanol is taken with Triomune 40 Tablet may reduce the blood levels of Butorphanol. This can lead to low treatment outcomes.

How to manage the interaction:
Although taking Triomune 40 Tablet and Butorphanol together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience watery eyes, runny nose, sneezing, yawning, excessive sweating, goose bumps, fever, chills, flushing, restlessness, irritability, anxiety, depression, pupil dilation, tremor, rapid heartbeat, body aches, involuntary twitching and kicking, abdominal cramping, loss of appetite, nausea, vomiting, diarrhea, and weight loss call a doctor right away. Do not discontinue any medications without consulting a doctor.
NevirapineAmiodarone
Severe
How does the drug interact with Triomune 40 Tablet:
Coadministration of Triomune 40 Tablet with Amiodarone may decrease the effects of amiodarone. This can lead to low treatment outcomes.

How to manage the interaction:
Taking Amiodarone with Triomune 40 Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or irregular heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
NevirapineLeflunomide
Severe
How does the drug interact with Triomune 40 Tablet:
Coadministration of Triomune 40 Tablet and leflunomide can increase the risk of liver problems.

How to manage the interaction:
Although there is an interaction between leflunomide and Triomune 40 Tablet, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
NevirapineOxycodone
Severe
How does the drug interact with Triomune 40 Tablet:
When Oxycodone is taken with Triomune 40 Tablet may reduce the blood levels of Oxycodone. This can lead to low treatment outcomes.

How to manage the interaction:
Although taking Triomune 40 Tablet and Oxycodone together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience watery eyes, runny nose, sneezing, yawning, excessive sweating, goose bumps, fever, chills, flushing, restlessness, irritability, anxiety, depression, pupil dilation, tremor, rapid heartbeat, body aches, involuntary twitching and kicking, abdominal cramping, loss of appetite, nausea, vomiting, diarrhoea, and weight loss call a doctor right away. Do not discontinue any medications without consulting a doctor.
NevirapineOlaparib
Severe
How does the drug interact with Triomune 40 Tablet:
When Olaparib is taken with Triomune 40 Tablet may reduce the blood levels of Olaparib. This can lead to low treatment outcomes.

How to manage the interaction:
There may be a possibility of interaction between Triomune 40 Tablet and Olaparib, but it can be taken if prescribed by a doctor. Do not discontinue any medications without first consulting a doctor.

Drug-Food Interactions

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LAMIVUDINE-150MG+NEVIRAPINE-200MG+STAVUDINE-40MGHigh fat foods
Mild

Drug-Food Interactions

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LAMIVUDINE-150MG+NEVIRAPINE-200MG+STAVUDINE-40MGHigh fat foods
Mild
Common Foods to Avoid:
Frozen Meals, Cheese, Red Meat, Potato Chips, Hamburgers, Hot Dogs, Ice Cream

How to manage the interaction:
Taking Triomune 40 Tablet with high fatty foods can reduce the effectiveness of Triomune 40 Tablet Avoid taking high-fat food while taking Triomune 40 Tablet, as this can lead to interaction.

Diet & Lifestyle Advise

  • Eat a healthy and balanced diet. Eat vitamin and nutrient-rich food such as dark green, yellow, orange and red vegetables, and fruit as it helps to boost your immune system. Option for lean protein and whole grains.
  • Avoid eating raw meat and eggs. Consume properly boiled and cooked meat, poultry or seafood.
  • Eat bland and low-fat foods and avoid spicy or oily foods if you experience nausea or vomiting.
  • Try to reduce emotional and physical stress by spending time with family or whatever makes you happy.
  • Drink more fluids and avoid alcoholic beverages to prevent dehydration. 
  • Wash your hands properly before and after eating.
  • Make sure you sleep at least 8 hours a day.

Habit Forming

No

Therapeutic Class

ANTIRETROVIRAL AGENTS

Triomune 40 Tablet 30's Substitute

Substitutes safety advice
  • Emtri 40 mg Tablet 30's

    by Others

    36.30per tablet
  • Nevilast 40 mg Tablet 10's

    by Others

    12.87per tablet

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • HYDROXYUREA
  • WARFARIN
  • BACTRIM

Special Advise

  • Triomune 40 Tablet 30's may still develop infections or other illnesses associated with HIV infection or AIDS. So, people taking Triomune 40 Tablet 30's should be carefully monitored throughout the treatment.
  • You can still infect other people while taking Triomune 40 Tablet 30's. So, use necessary precautions to avoid infecting others.
  • Triomune 40 Tablet 30's may cause abnormal liver function tests. So, regular monitoring of liver function is necessary while taking this medicine.

Disease/Condition Glossary

HIV infection: HIV (human immunodeficiency virus) is a virus that attacks the immune system, making the individual susceptible to other infections or illnesses. People with HIV experience flu-like symptoms such as fever, chills, rash, night sweats, muscle aches, tiredness and sore throat. These symptoms usually last for days to several weeks. It spreads through body fluids such as semen, vaginal fluid and blood. If left untreated, this condition can lead to AIDS (Acquired Immunodeficiency Syndrome). It is a life-long condition and there is no definite cure for it.  However, it can be controlled by treating with antiretroviral agents.

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