Nilitis 500 mg Tablet 10's

Written By Santoshini Reddy G , M Pharmacy

Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Prescription drug

MRP ₹50.8

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₹7.6 Cashback (15%)

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Whats That

About Nilitis 500 mg Tablet

Nilitis 500 mg Tablet belongs to a group of medicines called Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) indicated to relieve signs and symptoms of osteoarthritis and rheumatoid arthritis. Osteoarthritis is caused by the breakdown of the joint lining, whereas rheumatoid arthritis is caused by swelling of the joint linings.

Nilitis 500 mg Tablet contains Nabumetone, which works by blocking the effect of chemical messengers that cause pain, fever, and inflammation. Thereby, it helps treat osteoarthritis and rheumatoid arthritis.

In some cases, Nilitis 500 mg Tablet may cause side effects such as diarrhoea, nausea, constipation, stomach ache, and wind. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to the doctor if any of the side effects persist or worsen.

Avoid taking Nilitis 500 mg Tablet during the last three months of pregnancy or if you are breastfeeding. This medicine may cause dizziness; drive only if you are alert. Nilitis 500 mg Tablet is not recommended for children as safety and effectiveness have not been established. Keep your doctor informed about your health condition and medications to rule out any side effects/interactions.

Uses of Nilitis 500 mg Tablet

Osteoarthritis, rheumatoid arthritis.

Directions for Use

Take Nilitis 500 mg Tablet with or after a meal. Swallow the medicine as a whole with a glass of water; do not chew or break it.

Medicinal Benefits

Nilitis 500 mg Tablet belongs to a group of medicines called Non-Steroidal Anti-Inflammatory Drugs (NSAIDs), used to relieve pain, swelling, tenderness, stiffness, and swelling caused by osteoarthritis and rheumatoid arthritis. Nilitis 500 mg Tablet contains Nabumetone, which works by blocking the effect of chemical messengers that cause pain, fever, and inflammation. Thereby, it helps treat osteoarthritis and rheumatoid arthritis.

Storage

Keep Nilitis 500 mg Tablet out of reach and sight of children.

Side effects of Nilitis 500 mg Tablet

Loose And Watery Stools

Here are the precise steps to cope with diarrhoea caused by medication usage:

Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Indigestion

Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:

Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.

Stomach Pain

Drink water or other clear fluids.
To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
Include bland foods like rice, toast, crackers, and rice in your diet.
Avoid lying down immediately after eating as it may cause indigestion or heartburn.
Avoid acidic and spicy food as it may cause indigestion.

Constipation

Here are the steps to cope with constipation as a side effect of medication:

Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.

Gas Or Fart

Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:

Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.

Dizziness

Here are the 7 steps to manage Dizziness caused by medication:

Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
When standing up, do so slowly and carefully to avoid sudden dizziness.
Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

Trouble Falling/ Staying Asleep

Here are the 7 step-by-step strategies to manage the side effect of "inability to sleep" caused by medication usage:

Prepare for a restful night's sleep: Develop a calming pre-sleep routine, like reading or meditation, to help your body relax and prepare for sleep.
Create a sleep-conducive Environment: Make bedroom a sleep haven by ensuring it is quiet, dark and calm.
Follow a Sleep Schedule: Go to bed and get up at the same time every day to help regulate your body's internal clock and increase sleep quality.
Try relaxing techniques like deep breathing, mindfulness meditation and any others.
Limit stimulating activities before bedtime: Avoid stimulating activities before bedtime to improve sleep quality.
Monitor Progress: Keep track of your sleep patterns to identify areas for improvement.
Consult a doctor if needed: If these steps don't improve your sleep, consult a doctor for further guidance and therapy.

Drug Warnings

Do not take Nilitis 500 mg Tablet if you are allergic to any of its components, aspirin or NSAIDS, or if you have/had stomach/peptic ulcer, perforation, or bleeding, peptic disease, severe heart failure, liver cirrhosis, kidney failure, or if you are in the last three months of pregnancy or breastfeeding. Inform the doctor if you have/had asthma, stomach problems (Crohn’s disease or ulcerative colitis), liver, kidney or heart problems, high blood pressure, stroke, oedema, autoimmune diseases, diabetes, high cholesterol, infections, are in the first six months of pregnancy, smoker, or if you are above 65 years of age. Nilitis 500 mg Tablet is not recommended for children. Stop taking Nilitis 500 mg Tablet and consult a doctor immediately if you experience difficulty breathing, face or throat swelling, severe rash that may blister, chest pain or sudden numbness and confusion, blood in stools (black/tarry stools), or blood in vomit (dark particles that look like coffee granules). Do not take Nilitis 500 mg Tablet if you have recently had a heart attack unless prescribed by your doctor. Seek emergency medical help immediately if you experience symptoms such as chest pain, weakness in one part or side of the body, shortness of breath, or slurred speech. Nilitis 500 mg Tablet may cause gastrointestinal events, including bleeding, ulceration, and perforation of the stomach or intestines. If you experience any of the following symptoms, stop taking Nilitis 500 mg Tablet and consult your doctor: stomach pain, vomit that is bloody or looks like coffee grounds, heartburn, blood in the stool, or black and tarry stools.

Drug-Drug Interactions

NabumetoneKetorolac

Critical

NabumetoneNaproxen

Severe

Drug-Drug Interactions

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NabumetoneKetorolac

Critical

How does the drug interact with Nilitis 500 mg Tablet:
Using ketorolac together with Nilitis 500 mg Tablet may increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding and ulcers.

How to manage the interaction:
Taking Ketorolac with Nilitis 500 mg Tablet is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience any unusual bleeding, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not discontinue any medications without consulting a doctor.

NabumetoneNaproxen

Severe

How does the drug interact with Nilitis 500 mg Tablet:
Coadministration of Naproxen and Nilitis 500 mg Tablet can increase the risk or severity of gastric bleeding, ulceration, and rarely, perforation leading to serious blood loss.

How to manage the interaction:
Taking Naproxen and Nilitis 500 mg Tablet together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, or have other signs and symptoms of bleeding such as dizziness; lightheadedness; red or black, tarry stools; coughing up or vomiting fresh or dried blood that looks like coffee grounds; severe headache; and weakness, consult the doctor. Do not discontinue any medication without a doctor's advice.

NabumetoneDeferasirox

Severe

How does the drug interact with Nilitis 500 mg Tablet:
Taking Nilitis 500 mg Tablet and Deferasirox together can increase the risk of stomach bleeding and ulcers.

How to manage the interaction:
Co-administration of Nilitis 500 mg Tablet with Deferasirox can possibly result in an interaction, but it can be taken if your doctor has advised it. This risk is higher in older people with certain blood disorders or low platelet counts.If you have symptoms like stomach pain, bloating, dizziness, or black stools, it's important to consult a doctor. Do not stop using any medications without a doctor's advice.

NabumetonePrasugrel

Severe

How does the drug interact with Nilitis 500 mg Tablet:
Co-administration of Nilitis 500 mg Tablet with Prasugrel can increase the risk of bleeding and hemorrhage.

How to manage the interaction:
There may be a possibility of interaction between Prasugrel and Nilitis 500 mg Tablet, but it can be taken if prescribed by a doctor. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.

NabumetoneCelecoxib

Severe

How does the drug interact with Nilitis 500 mg Tablet:
Taking Nilitis 500 mg Tablet with celecoxib can increase the risk and severity of bleeding and ulcers of the stomach.

How to manage the interaction:
Although there is a interaction between Nilitis 500 mg Tablet and Celecoxib, but it can be taken if your doctor has advised it. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Do not discontinue any medication without consulting a doctor.

NabumetonePiroxicam

Severe

How does the drug interact with Nilitis 500 mg Tablet:
Coadministration of Nilitis 500 mg Tablet with Piroxicam can increase the risk of side effects inflammation(swelling with redness and pain), bleeding, ulceration, and perforation.

How to manage the interaction:
Co-administration of Piroxicam with Nilitis 500 mg Tablet can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without talking to a doctor.

NabumetoneApixaban

Severe

How does the drug interact with Nilitis 500 mg Tablet:
Coadministration of Nilitis 500 mg Tablet and Apixaban co-administration may raise the risk of bleeding.

How to manage the interaction:
Even though combining Nilitis 500 mg Tablet and Apixaban may cause an interaction, it is still possible to take it if your doctor advises you to. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Without consulting a doctor, never stop taking any medications.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30 minutes of walking or swimming would be helpful.
Performing yoga may also help in improving joint flexibility and pain management.
Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
Get adequate sleep, as resting the muscles can help in reducing inflammation and swelling.
Follow heat or cold therapy, and apply a cold or hot compress on the joints for 15-20 minutes regularly.
De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
Acupuncture, massage and physical therapy may also be helpful.
Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
Avoid smoking and alcohol consumption.

Side Effects of Nilitis 500 mg Tablet

Nausea
Vomiting
Diarrhoea
Constipation
Indigestion
Abdominal pain
Dizziness
Headache

Habit Forming

No

Therapeutic Class

NON-STEROIDAL DRUG

Author Details

Written By

Santoshini Reddy G

M Pharmacy

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 8, 2025 | 9:49 AM IST

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Drug-Diseases Interactions

No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

How does Nilitis 500 mg Tablet work?

Nilitis 500 mg Tablet works by blocking the effect of chemical messengers that cause pain and inflammation.

Does Nilitis 500 mg Tablet increase the risk of heart attack?

Nilitis 500 mg Tablet may be associated with a small increased risk of heart attack or stroke. This risk is more likely with prolonged treatment and high doses. Therefore, avoid exceeding the dose and duration of treatment suggested by the doctor. Also, inform the doctor if you have/had a stroke or heart problems.

I am planning for pregnancy. Can I take Nilitis 500 mg Tablet ?

Nilitis 500 mg Tablet might make it harder for you to become pregnant. If you are planning for pregnancy, ask your doctor for advice.

Drug-Drug Interactions Checker List

DULOXETINE
ESCITALOPRAM
FLUOXETINE
SERTRALINE
HYDROCHLOROTHIAZIDE
LISINOPRIL
PREDNISONE
METFORMIN

Special Advise

Your doctor may advise regular tests to monitor liver and kidney function.
If you are due to undergo CABG surgery (coronary artery bypass graft, a type of heart surgery), you should not take Nilitis 500 mg Tablet right before or right after the surgery.

Disease/Condition Glossary

Osteoarthritis: It is a joint disease in which the two ends of the joints come together due to the breakdown of a protective covering of cartilage. Due to the absence of this protective covering, the joints rub against each other, leading to pain and stiffness. Symptoms include pain, stiffness, inflammation and tenderness.

Rheumatoid arthritis: It is an auto-immune disease (the body's immune system attacks its tissue) which leads to joint pain and damage. Symptoms of rheumatoid arthritis include pain, swelling, stiffness, deformities and loss of joint function.