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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sunny S , MBBS

About NOBEL MR 2MG TABLET

NOBEL MR 2MG TABLET is a combination medicine used to relieve pain due to muscle spasms such as arthritis, muscle pain, tooth pain, bone and joint pain, headache, and period pain. Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Muscle spasm is the sudden involuntary contractions of the muscle, which can be painful and uncomfortable.
 
NOBEL MR 2MG TABLET contains Nimesulide (analgesic), Paracetamol (mild analgesic and fever reducer), and Tizanidine (muscle relaxant). Nimesulide and Paracetamol work by blocking the effect of chemical messengers that cause pain and inflammation at the injured or damaged site. Tizanidine works on the centres of the spinal cord and brain, which helps relieve muscle stiffness, thereby improving muscle movements. Together, NOBEL MR 2MG TABLET helps in reducing pain due to muscle spasms.
 
You are advised to take NOBEL MR 2MG TABLET for as long as your doctor has prescribed it for you depending on your medical condition. You may experience certain common side-effects such as nausea, vomiting, dizziness, dry mouth, and diarrhoea in some cases. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.
 
Consult your doctor if you are pregnant or breastfeeding. NOBEL MR 2MG TABLET may cause dizziness, so drive with caution. NOBEL MR 2MG TABLET should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol with NOBEL MR 2MG TABLET as it could lead to increased dizziness; it might also increase the risk of stomach bleeding. Keep your doctor informed about your health condition and medicines to rule out any side-effects. 

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Whats That

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Non returnable*
COD available

Online payment accepted

Manufacturer/Marketer

Mankind Pharma Ltd

Consume Type

ORAL

Return Policy

3 Days Returnable

Expires on or after

Apr-24

for this medicine

Uses of NOBEL MR 2MG TABLET

Musculoskeletal pain, Muscle spasms, Arthritis

Medicinal Benefits

NOBEL MR 2MG TABLET is a combination of three drugs, namely: Tizanidine, Nimesulide, and Paracetamol. NOBEL MR 2MG TABLET is a combination medicine used to relieve pain and inflammation associated with osteoarthritis,  muscle pain, tooth pain, bone and joint pain, headache, and period pain. Tizanidine is a muscle relaxant that works on the centres of the spinal cord and brain. This helps relieve muscle stiffness and improves muscle movements. Nimesulide and Paracetamol are analgesics that work by blocking the effect of chemical messengers that cause pain and inflammation at the injured or damaged site. Together, NOBEL MR 2MG TABLET helps in relieving pain due to muscle spasms. 

Side Effects of NOBEL MR 2MG TABLET

  • Nausea
  • Vomiting
  • Dizziness
  • Diarrhoea
  • Dry mouth
  • Loss of appetite
  • Indigestion

Directions for Use

Swallow NOBEL MR 2MG TABLET as a whole with a glass of water, do not chew, or break it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take NOBEL MR 2MG TABLET if you are allergic to any of its contents, if you have/had severe heart problems, stomach ulcer or perforation, and bleeding problems such as bleeding from the stomach, intestine, or brain, bypass surgery, heart attack, blood circulation problems, or inflammation of intestines. Inform your doctor if you have high blood pressure, heart problems, high cholesterol, diabetes, asthma, inflammatory bowel disease, liver or kidney problems. Consult your doctor if you are pregnant or breastfeeding. NOBEL MR 2MG TABLET may cause dizziness, so drive only if you are alert. NOBEL MR 2MG TABLET is not recommended for children as safety and effectiveness have not been established. Stop taking NOBEL MR 2MG TABLET and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools. Do not take any other analgesic for pain relief along with NOBEL MR 2MG TABLET unless prescribed.  

Therapeutic Class

ANALGESICS

Drug-Drug Interactions

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TizanidineFluvoxamine
Critical
TizanidineDronedarone
Critical

Drug-Drug Interactions

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TizanidineFluvoxamine
Critical
How does the drug interact with NOBEL MR 2MG TABLET:
Taking Fluvoxamine with NOBEL MR 2MG TABLET it can increases the risk of side effects.

How to manage the interaction:
Although Fluvoxamine with NOBEL MR 2MG TABLET is not recommended, but can be taken together if prescribed by a doctor. However, if you experience drowsiness, dizziness, low blood pressure, slurred speech, confusion, or severe weakness, contact your doctor immediately. Do not stop using any medications without consulting a doctor.
TizanidineDronedarone
Critical
How does the drug interact with NOBEL MR 2MG TABLET:
Coadministration of NOBEL MR 2MG TABLET with Dronedarone can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking NOBEL MR 2MG TABLET with Dronedarone is generally avoided as it can result in an interaction, it can be taken when prescribed by a doctor. If you experience sudden dizziness, shortness of breath, palpitations, or chest pain, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
TizanidineCiprofloxacin
Critical
How does the drug interact with NOBEL MR 2MG TABLET:
Coadministration of Ciprofloxacin and NOBEL MR 2MG TABLET together can increase the risk of side effects.

How to manage the interaction:
Using Ciprofloxacin and NOBEL MR 2MG TABLET together is avoided, as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience drowsiness, weakness, sweating, or palpitations contact the doctor immediately. Do not discontinue any medications without consulting the doctor.
TizanidineZiprasidone
Critical
How does the drug interact with NOBEL MR 2MG TABLET:
Co-administration of NOBEL MR 2MG TABLET with Ziprasidone can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking NOBEL MR 2MG TABLET with Ziprasidone is not recommended, as it can result in an interaction, but it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting. Do not discontinue any medications without consulting a doctor.
TizanidineCisapride
Critical
How does the drug interact with NOBEL MR 2MG TABLET:
Coadministration of NOBEL MR 2MG TABLET with Cisapride can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking NOBEL MR 2MG TABLET with Cisapride is avoided as it can result in an interaction, it can be taken if your doctor has advised it. Contact your doctor immediately if you experience sudden dizziness, shortness of breath, palpitations, or vomiting. Do not discontinue any medications without consulting your doctor.
TizanidineSaquinavir
Critical
How does the drug interact with NOBEL MR 2MG TABLET:
Combining NOBEL MR 2MG TABLET with Saquinavir can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking NOBEL MR 2MG TABLET with Saquinavir is not recommended, as it can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhoea or vomiting, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
TizanidineCaffeine
Severe
How does the drug interact with NOBEL MR 2MG TABLET:
Coadministration of Caffeine with NOBEL MR 2MG TABLET may increase the blood levels and effects of NOBEL MR 2MG TABLET. This may cause excessive blood pressure, especially when rising from a sitting or lying position.

How to manage the interaction:
Although there is an interaction, caffeine can be taken with NOBEL MR 2MG TABLET if prescribed by the doctor. Contact your doctor if you experience dizziness, excessive sweating, or palpitations. Do not stop using any medicine without consulting your doctor.
TizanidineMoxifloxacin
Severe
How does the drug interact with NOBEL MR 2MG TABLET:
Using moxifloxacin together with NOBEL MR 2MG TABLET can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction between NOBEL MR 2MG TABLET and Moxifloxacin, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you experience symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without first talking to your doctor.
TizanidinePethidine
Severe
How does the drug interact with NOBEL MR 2MG TABLET:
Combining NOBEL MR 2MG TABLET with Pethidine can increase the risk of CNS depression.

How to manage the interaction:
Although taking NOBEL MR 2MG TABLET and Pethidine together can evidently cause an interaction, but it can be taken if your doctor has suggested it. Contact your doctor immediately if you notice any symptoms like dizziness, drowsiness, difficulty concentrating, impaired judgment, reaction speed, and motor coordination. Avoid alcohol, driving, or operating hazardous machinery until you know how they affect you, and avoid self-medication. Do not discontinue any medications without consulting your doctor.
TizanidineDolasetron
Severe
How does the drug interact with NOBEL MR 2MG TABLET:
Combining NOBEL MR 2MG TABLET and Dolasetron can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking NOBEL MR 2MG TABLET and Dolasetron together can lead to an interaction, but it can be taken if your doctor advises. However, contact your doctor immediately if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhoea, or vomiting. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • HYDROCODONE
  • ESCITALOPRAM
  • DULOXETINE
  • SERTRALINE
  • LITHIUM
  • METHOTREXATE
  • CYCLOSPORINE
  • ZOLPIDEM
  • PREGABALIN
  • DIPHENHYDRAMINE
  • CETIRIZINE

Diet & Lifestyle Advise

  • Exercising regularly helps in muscle stretching so that they are less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.
  • Massages can also be helpful.
  • Avoid freezing and hot temperatures.
  • Avoid wearing tight-fitting clothes, instead, wear loose garments.
  • Rest well, and get plenty of sleep.
  • To avoid developing pressure sores, change your position every two hours.
  • Hot or cold therapy can help treat muscle spasms. Apply an ice-pack or hot-pack on the muscle for 15-20minutes.
  • Stay hydrated, drink plenty of water.

Habit Forming

No

Special Advise

  • Do not use NOBEL MR 2MG TABLET when you need muscle tone for safe balance and body movement during various activities. In some cases, it may be dangerous for you to have reduced muscle tone.

Author Details

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Disease/Condition Glossary

Musculoskeletal pain: Musculoskeletal pain affects the bones, muscles, ligaments, tendons, and nerves. It can be acute or chronic, can be localized or wide-spread. The pain can be mild or severe enough to interfere with your daily routine. Musculoskeletal pain could occur due to arthritis, osteoporosis, fractures, dislocations, problems with the bone structure, or injury to the bones, joints, tendons, muscles, and ligaments. Symptoms of musculoskeletal pain include stiffness, swelling, redness, weakness, muscle spasms or twitching, trouble moving the affected area, and soreness

Arthritis: It is a joint disease in which the two ends of the joints come together due to the breakdown of a protective covering called cartilage. Due to the absence of this protective covering, the joints rub against each other, leading to pain and stiffness. Symptoms include pain, stiffness, inflammation, and tenderness. 

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