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Written By Veda Maddala , M Pharmacy
Reviewed By Sureshvarma D , MPharma
Non returnable*
COD available

Online payment accepted

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Whats That

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Composition :

NORETHISTERONE-5MG

Manufacturer/Marketer :

Wellesta Healthcare Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Offday Tablet

Offday Tablet belongs to the class of medicines called progestogens used to treat heavy, painful, or irregular periods, premenstrual syndrome (PMS), and endometriosis. Additionally, Offday Tablet may be used in the treatment of breast cancer. Endometriosis is a disorder in which the uterus's tissue lining (endometrium) grows on the ovaries, bowel, or tissues lining the pelvis. The most common symptom is pelvic pain.

Offday Tablet contains Norethisterone that works by mimicking the activity of the natural hormone progesterone. Thereby, it restores hormone levels in the body and regulates the growth and shedding of the womb lining. Thus, it helps to treat menstrual disorders.

Take Offday Tablet as prescribed by your doctor. You are advised to take Offday Tablet for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience unusual vaginal bleeding or spotting, dizziness, dry mouth, constipation, nausea, diarrhea, headache, breast pain, and tenderness. Most of these side effects of Offday Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Offday Tablet or any other medicines, please tell your doctor. Offday Tablet is not recommended for pregnant women as it may harm the unborn baby. If you are breastfeeding, consult a doctor before taking Offday Tablet . It is advised to use effective non-hormonal contraceptives such as condoms to avoid pregnancy while taking Offday Tablet . You are advised to stop smoking while taking Offday Tablet as it may increase the risk of adverse effects.

Uses of Offday Tablet

Heavy, painful or irregular periods, Premenstrual syndrome (PMS), Endometriosis, Breast cancer

Directions for Use

Take Offday Tablet with or without food as advised by your doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Medicinal Benefits

Offday Tablet contains Norethisterone, a synthetic hormone that mimics the activity of the natural hormone progesterone. Thereby, it restores hormone levels in the body and regulates the growth and shedding of the womb lining. Thus, it helps to treat menstrual disorders.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Offday Tablet

  • Unusual vaginal bleeding or spotting
  • Dizziness
  • Dry mouth
  • Constipation
  • Abdominal pain/cramps
  • Nausea
  • Diarrhea
  • Headache
  • Breast pain and tenderness

Drug Warnings

If you are allergic to Offday Tablet or any other medicines, please tell your doctor. Offday Tablet is not recommended for pregnant women as it may harm an unborn baby. If you are breastfeeding, consult a doctor before taking Offday Tablet . It is advised to use effective non-hormonal contraceptives such as condoms to avoid pregnancy while taking Offday Tablet . You are advised to stop smoking while taking Offday Tablet as it may increase the risk of adverse effects. If you are about to undergo any surgery, please inform your doctor that you are taking Offday Tablet as it may increase the effect of certain anesthetics. If you experience sudden shortness of breath, rapid heartbeat, sudden, severe, sharp pain in the chest, or cough up blood, stop taking Offday Tablet and consult a doctor immediately as these might be signs of a blood clot in the lungs.

Drug-Drug Interactions

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NorethisteronePhenobarbital
Severe
NorethisteroneTranexamic acid
Severe

Drug-Drug Interactions

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NorethisteronePhenobarbital
Severe
How does the drug interact with Offday Tablet:
The combined use of Offday Tablet and phenobarbital can reduce the blood levels and effects of Offday Tablet.

How to manage the interaction:
Although taking phenobarbital and Offday Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. If you experience any symptoms like abnormal bleeding, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
NorethisteroneTranexamic acid
Severe
How does the drug interact with Offday Tablet:
Using tranexamic acid together with norethindrone may increase the risk of blood clots.

How to manage the interaction:
Taking Offday Tablet with tranexamic acid can lead to an interaction, however, it can be taken only if a doctor has advised it. If you experience symptoms such as chest pain, shortness of breath, coughing up blood, blood in the urine, sudden loss of vision, and pain, redness, or swelling in your arm or leg, contact a doctor immediately .Do not discontinue any medications without consulting a doctor.
NorethisteroneCarbamazepine
Severe
How does the drug interact with Offday Tablet:
Taking carbamazepine and Offday Tablet may possibly reduce the effects of Offday Tablet which may result in higher risk of breakthrough bleeding and unexpected pregnancy.

How to manage the interaction:
Although taking carbamazepine and Offday Tablet together can result in an interaction, it can be taken if your doctor has prescribed it. Contact your doctor if you experience hot flashes, vaginal dryness, or uncontrolled bleeding. Do not discontinue any medications without consulting a doctor.
NorethisteroneDabrafenib
Severe
How does the drug interact with Offday Tablet:
Coadministration of Offday Tablet with Dabrafenib can reduce the metabolism and decrease the levels of Offday Tablet in the body.

How to manage the interaction:
Taking Offday Tablet with Dabrafenib together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of hot flashes, vaginal dryness, or abnormal bleeding, contact a doctor immediately. Do not stop using any medications without talking to a doctor.
NorethisteroneTelaprevir
Severe
How does the drug interact with Offday Tablet:
Using Telaprevir and Offday Tablet together can increase risk of unintended pregnancy and decrease the effectiveness of norethindrone.

How to manage the interaction:
Combining Telaprevir with Offday Tablet can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any symptoms like increased hot flashes, vaginal dryness, or menstrual abnormalities, contact the doctor immediately. Do not discontinue any medications without consulting a doctor.
NorethisteroneBexarotene
Severe
How does the drug interact with Offday Tablet:
Coadministration of Bexarotene and Offday Tablet together can decrease the effectiveness of norethindrone and increase the risk of unintended pregnancy.

How to manage the interaction:
Combining Bexarotene with Offday Tablet can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any symptoms like increased hot flashes, vaginal dryness, or menstrual abnormalities, contact the doctor immediately. Do not discontinue any medications without consulting a doctor.
NorethisteroneBoceprevir
Severe
How does the drug interact with Offday Tablet:
Using Boceprevir and Offday Tablet together can reduce the blood levels and decrease the effectiveness of norethindrone.

How to manage the interaction:
Combining Boceprevir with Offday Tablet can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any symptoms like increased hot flashes, vaginal dryness, or menstrual abnormalities, abnormal bleeding, contact the doctor immediately. Do not discontinue any medications without consulting a doctor.
NorethisteroneEslicarbazepine
Severe
How does the drug interact with Offday Tablet:
Eslicarbazepine may reduce the effects of Offday Tablet and its blood levels.

How to manage the interaction:
Although taking Eslicarbazepine and Offday Tablet results in an interaction, they can be taken together if prescribed by your doctor. Do not stop using any medications without consulting a doctor.
NorethisteroneMycophenolic acid
Severe
How does the drug interact with Offday Tablet:
Coadministration of Offday Tablet and Mycophenolic acid can decrease the levels and effects of Offday Tablet.

How to manage the interaction:
There could be a possible interaction between Mycophenolic acid and Offday Tablet, but they can be taken together if your doctor has prescribed them. However, if you experience hot flashes, vaginal dryness, or abnormal bleeding consult a doctor. Do not discontinue any medications without a doctor's advice.
NorethisteroneAmprenavir
Severe
How does the drug interact with Offday Tablet:
Coadministration of Amprenavir and Offday Tablet together may reduce amprenavir effects.

How to manage the interaction:
Combining Amprenavir with Offday Tablet can result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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NORETHISTERONE-5MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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NORETHISTERONE-5MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
Consuming Grapefruit juice may increase the blood levels of Offday Tablet. Avoid or limit the consumption of grapefruit and grapefruit juice while taking the Offday Tablet dose. Avoid or limit the consumption of grapefruit and grapefruit juice while taking the Offday Tablet dose.

Diet & Lifestyle Advise

  • Avoid fried and processed foods.
  • Include fiber-rich foods like whole grains, fruits, and vegetables in your diet.
  • Avoid refined carbohydrates that are high in sugars.
  • Replace animal proteins (like eggs, fish, and meat) with vegetable protein sources (nuts, seeds, and beans).
  • Avoid drinking excess alcohol or caffeinated drinks as they can worsen the symptoms.
  • Maintain a healthy weight, do moderate exercise regularly.
  • Avoid smoking and alcohol intake.

Habit Forming

No

Therapeutic Class

PROGESTIN

Offday Tablet Substitute

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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Offday Tablet contains Norethisterone, a synthetic hormone that works by mimicking the activity of the natural hormone progesterone. Thereby, it restores hormone levels in the body and regulates the growth and shedding of the womb lining. Thus, it helps to treat menstrual disorders.

Offday Tablet may be used to delay periods. Offday Tablet keeps progesterone levels high and prevents shedding of the womb lining. However, please consult a doctor before using Offday Tablet .

Offday Tablet may increase the risk of a blood clot in the veins of the leg, especially if you are overweight, smoking, or have a history of a blood clot in the lungs or veins, repeated miscarriage or have major surgery, serious injury, or systemic lupus erythematosus (autoimmune disease). Therefore, please inform your doctor if you have any of these conditions before taking Offday Tablet .

You are not recommended to take Offday Tablet with rifampicin as it may decrease the levels of Offday Tablet in blood and reduce its effectiveness. However, please consult a doctor before taking Offday Tablet with other medicines.

Periods usually resume within 3 days of discontinuing Offday Tablet . However, please consult a doctor if you have any concerns regarding this.

Offday Tablet may cause changes in blood sugar levels. Therefore, it is advised to regularly monitor blood sugar levels while taking Offday Tablet and inform your doctor if you have diabetes before taking Offday Tablet .

Drug-Drug Interactions Checker List

  • CARBAMAZEPINE
  • PHENYTOIN
  • NELFINAVIR
  • RITONAVIR
  • AMINOGLUTETHIMIDE
  • COTRIMOXAZOLE
  • RIFAMPICIN
  • TETRACYCLINE
  • CICLOSPORIN

Special Advise

  • Offday Tablet may interfere with certain laboratory tests. Therefore, inform your doctor that you are taking Offday Tablet before undergoing any tests.

Disease/Condition Glossary

Endometriosis: It is a disorder in which the tissue lining the uterus (endometrium) grows on the ovaries, bowel, or tissues lining the pelvis. The most common symptom is pelvic pain. Other symptoms of endometriosis include lower back pain, painful periods, heavy menstrual bleeding, pain following sexual intercourse, or discomfort with bowel movements. 

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