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Reviewed By Sunny S , MBBS
Non returnable*
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Composition :

ONDANSETRON-4MG

Manufacturer/Marketer :

Alkem Laboratories Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Ondem Sachet 4 gm

Ondem Sachet 4 gm belongs to a group of medications called ' anti-emetics' primarily used in the prevention of vomiting (being sick) and nausea (feeling sick) that usually occur after cancer chemotherapy, radiation treatment or surgery. Nausea is an uneasy feeling in which a person feels an urge to vomit while vomiting is the natural response to the body to forcefully discharge the stomach contents.

Ondem Sachet 4 gm contains 'Ondanestron' that works by blocking the action of a chemical in the body (serotonin) responsible for causing nausea and vomiting. As a result, Ondem Sachet 4 gm prevents the sensation of nausea and vomiting caused due to conditions like surgery, cancer chemotherapy, pregnancy or motion sickness.

Take Ondem Sachet 4 gm as prescribed. Your doctor will advise you on how often you take Ondem Sachet 4 gm based on your medical condition. A person taking Ondem Sachet 4 gm often experience side effects that include a feeling of warmth, constipation, headache, diarrhoea, headache, drowsiness, feeling of tiredness. Although, not every person faces the side effects of Ondem Sachet 4 gm, and even some of the unpleasant effects of Ondem Sachet 4 gm do not require medical attention.

The use of Ondem Sachet 4 gm is restricted in persons who are allergic to any of the ingredients present in this medicine. Tell your doctor if you are facing liver, kidney, or heart disorders. Ondem Sachet 4 gm should be used during pregnancy or breastfeeding after consulting a doctor. Ondem Sachet 4 gm contains lactose so tell your doctor if you have an intolerance to some sugars.

Uses of Ondem Sachet 4 gm

Nausea, Vomiting

Directions for Use

Tablet: It can be taken with or without a meal as advised by the doctor. Swallow the tablet as a whole with a glass of water. Do not break, crush or chew it. Oral disintegrating tablet/Mouth dissolving tablet (tablet MD): Check the label for directions before use. Do not handle the tablet with wet hands. Place the tablet in the mouth and allow it to dissolve. Do not swallow it as a whole.Syrup/Suspension: Shake the bottle well before use and take it as prescribed by your doctor with a measuring cup or spoon.

Medicinal Benefits

Ondem Sachet 4 gm belongs to a group of medications called anti-emetics used to prevent nausea and vomiting associated with conditions like cancer chemotherapy, radiotherapy, surgery, pregnancy and motion sickness in adults and children above 4 years of age. When serotonin level increases in the blood, it stimulates the CTZ receptor (chemoreceptor trigger zone) located in the brain responsible for controlling nausea and vomiting. Ondem Sachet 4 gm acts by inhibiting the release of this serotonin, thereby preventing nausea and vomiting. 

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Tell your doctor if you are dealing with an uneven heart, liver problems, or any other problem. Tell your doctor if you are taking medicine for epilepsy, cancer medicines, and abnormal heartbeats. Ondem Sachet 4 gm may affect a person's ability to drive. Therefore, should avoid driving or operating any machine. People with an irregular heartbeat (arrhythmia), and phenylketonuria (too much of protein phenylalanine in the blood) should not take Ondem Sachet 4 gm as it may cause serious conditions. The liver patient should not take more than 8 mg of Ondem Sachet 4 gm daily. Ondem Sachet 4 gm should be used during pregnancy or breastfeeding after consultation with a doctor. Taking Ondem Sachet 4 gm with apomorphine can cause a sharp dip in blood pressure, even leading to death, so avoid its intake together.

Drug-Drug Interactions

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OndansetronAnagrelide
Severe

Drug-Drug Interactions

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How does the drug interact with Ondem Sachet 4 gm:
Taking Ondem Sachet 4 gm with Ziprasidone can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Ondem Sachet 4 gm with Ziprasidone is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
OndansetronAnagrelide
Severe
How does the drug interact with Ondem Sachet 4 gm:
Taking Ondem Sachet 4 gm with anagrelide increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Co-administration of Ondem Sachet 4 gm alongside anagrelide can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, get medical help immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Ondem Sachet 4 gm:
When Ondem Sachet 4 gm is taken with fluvoxamine, can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in body).

How to manage the interaction:
Co-administration of Ondem Sachet 4 gm along with fluvoxamine can result in an interaction, it can be taken if a doctor has advised it. However, if you have sudden dizziness, lightheadedness, fainting, confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles, or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea, or fast or rapid heartbeats during therapy, consult the doctor. Do not discontinue any medications without a doctor's advice.
OndansetronBedaquiline
Severe
How does the drug interact with Ondem Sachet 4 gm:
Taking Ondem Sachet 4 gm with bedaquiline increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Co-administration of Ondem Sachet 4 gm along with bedaquiline can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, get medical help immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Ondem Sachet 4 gm:
Taking Ondem Sachet 4 gm with crizotinib increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Although taking Ondem Sachet 4 gm along with crizotinib can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Ondem Sachet 4 gm:
Taking Ondem Sachet 4 gm with disopyramide increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Although taking Ondem Sachet 4 gm along with disopyramide can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Ondem Sachet 4 gm:
Coadministration of Ondem Sachet 4 gm with Trazodone may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increase in body).

How to manage the interaction:
Although taking Ondem Sachet 4 gm along with trazodone can result in an interaction but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination (seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Ondem Sachet 4 gm:
Coadministration of Ondem Sachet 4 gm with ivabradine can increase the risk of an abnormal heart rhythm.

How to manage the interaction:
Co-administration of Ondem Sachet 4 gm along with ivabradine can result in an interaction, it should be taken only if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Ondem Sachet 4 gm:
When Ondem Sachet 4 gm, is taken with tranylcypromine it increases the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in body).

How to manage the interaction:
Although taking Ondem Sachet 4 gm along with tranylcypromine can lead to an interaction, it can be taken if recommended by a doctor. However, if you experience symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, a shaking sensation, incoordination, stomach cramp, nausea, vomiting, and diarrhea, see a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Ondem Sachet 4 gm:
Co-administration of Ondem Sachet 4 gm and Dextromethorphan may increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Although there is a possible interaction between Ondem Sachet 4 gm and Dextromethorphan, you can take these medicines together if prescribed by a doctor. However, if you experience symptoms such as seizures (fits), extreme changes in blood pressure, confusion, hallucination, increased heart rate, fever, excessive sweating, shivering or shaking, tremors, incoordination, blurred vision, muscle spasms or stiffness, nausea, vomiting, stomach cramp, and diarrhea, contact a doctor immediately. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A person should take a healthy diet that includes lots of fruits and vegetables, lean meats, skinless poultry, nuts, fish, whole grains, plant-based oils, and low-fat dairy products will help to keep a person in good health and avoid chances of nausea and vomiting. 
  • One should avoid taking greasy or oily foods as this food triggers nausea and vomit.
  • Eat cool foods instead of hot and spicy foods.
  • Include clear broths, non-fat yoghurt, fruit juice, sherbet, and sports drinks for fluid make up which has got lost due to vomiting. 

 

Habit Forming

No

Therapeutic Class

ANTIEMETICS

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Ondem Sachet 4 gm is an anti-sickness medicine that takes about 1-2 hours to show its action.

Tell your doctor if you are facing severe constipation as after checking your condition, the doctor will decide that you can take this medicine or not.

Ondem Sachet 4 gm may cause changes in the vision, so one should avoid driving or operating any machine that required mental alertness.

People with an irregular heartbeat (arrhythmia), and phenylketonuria (too much of protein phenylalanine in the blood) should not take Ondem Sachet 4 gm as it may cause serious conditions. The liver patient should not take more than 8 mg of Ondem Sachet 4 gm daily. Taking Ondem Sachet 4 gm with apomorphine can cause a sharp dip in blood pressure, even leading to death, so avoid its intake together.

Drug-Drug Interactions Checker List

  • ACETAMINOPHEN
  • TRAMADOL
  • IBUPROFEN
  • PREGABALIN
  • LORAZEPAM

Special Advise

  • Do not use Ondem Sachet 4 gm with Apomorphine as it can cause a sudden fall of blood pressure leading to death or coma.
  • Ondem Sachet 4 gm contains 'phenylalanine' so if you have Phenylketonuria (PKU) avoid its intake. 

Disease/Condition Glossary

Nausea/Vomiting: Nausea is an uneasy feeling in the stomach that may come and go in waves in which a person feels with a strong urge to vomit. It happens before vomiting. While vomiting is a natural response of the body in which a person wants to expel stomach contents from the mouth forcefully. It can be triggered by taste, anxiety, smell, pain, or irritation to the stomach. Usually, a person faces nausea and vomiting as the unpleasant effects of cancer therapy after chemotherapy and radiation therapy. It is essential to control vomiting and nausea in cancer patients for performing everyday activities of the day. If not controlled, it can lead to mental changes, loss of appetite, malnutrition, and dehydration.

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