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Written By Veda Maddala , M Pharmacy
Reviewed By Sunny S , MBBS
Non returnable*
COD available

Online payment accepted

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Manufacturer/Marketer

Klm Laboratories Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Onitraz Capsule

Onitraz Capsule belongs to a class of drugs called antifungals used to treat fungal infections of the mouth, throat, toenails, fingernails or lungs. Fungal infection is a disease in which a fungus attacks the tissue and causes infection. Fungal infections may be contagious (spread from one person to another).

Onitraz Capsule contains Itraconazole, an antifungal that works by inhibiting the production of ergosterol (a main component of cell membranes of fungi). Thereby, weakens and damages the fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, causes the main components of fungal cells to leak out and kill fungi and clear the fungal infection.

Take Onitraz Capsule as prescribed. Your doctor will advise you on how often you take Onitraz Capsule based on your medical condition. Some people may experience nausea, headache, diarrhoea, tiredness, cough, cold, throat pain, back pain and stomach pain. Most of these side effects of Onitraz Capsule do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Onitraz Capsule or any other medicines, please tell your doctor. Onitraz Capsule is a pregnancy category C drug and may cause harm to the unborn baby. However, if you are pregnant, planning for pregnancy or a nursing mother, it is advised to consult a doctor before using Onitraz Capsule. Do not take Onitraz Capsule if you have or had heart failure as it may cause severe life-threatening adverse effects. If you have kidney, liver, heart or lung problems, inform your doctor before taking Onitraz Capsule. Avoid taking fentanyl (a strong opioid narcotic medicine) with Onitraz Capsule as it may cause severe breathing problems and can even lead to death. If you experience numbness or tingling in your hands or feet, stop taking Onitraz Capsule and consult your doctor immediately as they might be symptoms of nerve damage.

Uses of Onitraz Capsule

Fungal infections

Directions for Use

Tablet: Take it with food to avoid stomach upset or as advised by the doctor. Swallow the whole tablet with a glass of water. Do not break, crush or chew it. If you are taking any stomach acid suppressor or have achlorhydria (stomach does not produce hydrochloric acid), take Onitraz Capsule with cola. Oral suspension: Shake the bottle well before use and take it on an empty stomach at least 1 or 2 hours before meals as prescribed by your doctor with a measuring cup or spoon provided.

Medicinal Benefits

Onitraz Capsule is an antifungal used to treat fungal infections of the mouth, throat, toenails, fingernails or lungs. The fungal cell membranes are essential for their survival as they prevent the entry of unwanted substances into the cells and stops the leakage of cell contents. Onitraz Capsule inhibits the production of ergosterol (a main component of cell membranes of fungi). Thereby, weakens and damages the fungal cell membranes causing the main components of fungal cells to leak out. Thus, kills fungi and clears the fungal infection.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Onitraz Capsule

  • Nausea
  • Headache
  • Diarrhoea
  • Tiredness
  • Cough
  • Cold
  • Throat pain
  • Back pain
  • Stomach pain

Drug Warnings

If you are known to be allergic to Onitraz Capsule or any other medicines, please tell your doctor. Onitraz Capsule is a pregnancy category C drug and may cause harm to the unborn baby. However, if you are pregnant, planning for pregnancy, or are a nursing mother, it is advised to consult a doctor before using Onitraz Capsule. Avoid taking fentanyl (a strong opioid pain killer narcotic medicine) with Onitraz Capsule, as it may cause severe breathing problems and can even lead to death. Do not take Onitraz Capsule if you had heart failure as it may cause severe life-threatening adverse effects. If you experience a yellow colour change of your eyes or skin, dark coloured urine, stomach pain, pale stools, loss of appetite, unusual tiredness, vomiting or nausea, stop taking Onitraz Capsule and consult a doctor immediately as they might be symptoms of liver failure. If you have kidney, liver, heart, or lung problems, inform your doctor before taking Onitraz Capsule.

Drug-Drug Interactions

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ItraconazoleIsavuconazole
Critical
ItraconazoleAvanafil
Critical

Drug-Drug Interactions

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ItraconazoleIsavuconazole
Critical
How does the drug interact with Onitraz Capsule:
The blood levels and effects of Isavuconazole may be significantly enhanced by taking Onitraz Capsule along with it.

How to manage the interaction:
Co-administration of Isavuconazole and Onitraz Capsule can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like nausea, vomiting, or diarrhoea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
ItraconazoleAvanafil
Critical
How does the drug interact with Onitraz Capsule:
Co-administartion of avanafil and Onitraz Capsule may considerably raise the blood levels of Avanafil.

How to manage the interaction:
Although combining avanafil and Onitraz Capsule may possibly lead to an interaction, they can be taken if prescribed by a doctor. Consult a physician if you develop any side effects, including priapism (prolonged and painful erection unrelated to sexual activity), low blood pressure, fainting, visual problems, including loss of vision, ringing in the ears, hearing loss, and low blood pressure. Without consulting a doctor, never stop taking any medication.
ItraconazoleNisoldipine
Critical
How does the drug interact with Onitraz Capsule:
The blood levels and effects of nisoldipine may be greatly increased when used with Onitraz Capsule.

How to manage the interaction:
Nisoldipine and Onitraz Capsule may interact, but if prescribed by a doctor, they can be used together. Consult a physician if you have symptoms that include an irregular heartbeat, accumulation of fluid in legs or hands, or abnormally low blood pressure. Without consulting a doctor, never stop taking any medication.
ItraconazoleTolvaptan
Critical
How does the drug interact with Onitraz Capsule:
Co-administration of Tolvaptan and Onitraz Capsule may significantly raise Tolvaptan blood levels and effects.

How to manage the interaction:
There may be a possibility of interaction between Tolvaptan and Onitraz Capsule, but it can be taken if prescribed by a doctor. If you notice any of these signs -difficulty swallowing, trouble speaking, muscle weakness, trouble controlling body movements, confusion, mood changes, seizures, call a doctor right away. Do not stop using any medications without a doctor's advice.
ItraconazoleSimvastatin
Critical
How does the drug interact with Onitraz Capsule:
Simvastatin's blood levels and effects may be greatly increased when combined with Onitraz Capsule.

How to manage the interaction:
Simvastatin and Onitraz Capsule may interact, but if prescribed by a doctor, they can be used together. Consult a doctor if you have side effects such unexplained pain in the muscles or tenderness, muscle weakness, fever or flu-like symptoms, or dark urine. Without consulting a doctor, never stop taking any medication.
ItraconazoleFelodipine
Critical
How does the drug interact with Onitraz Capsule:
The blood levels and effects of felodipine may be considerably increased by taking Onitraz Capsule together with felodipine.

How to manage the interaction:
Although there is a possible interaction between felodipine and Onitraz Capsule, they can be taken if prescribed by a doctor. Consult a physician if you have an irregular heartbeat, Edema (accumulation of fluid in hands or legs), or abnormally low blood pressure. Without first consulting a doctor, never stop taking medicines.
ItraconazoleTicagrelor
Critical
How does the drug interact with Onitraz Capsule:
The blood levels and effects of ticagrelor may be greatly increased when combined with Onitraz Capsule.

How to manage the interaction:
Onitraz Capsule and ticagrelor may interact, however if prescribed by a physician, they can be used together. While receiving therapy, you should consult a doctor if you develop any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Without consulting a doctor, never stop taking any medication.
ItraconazoleCisapride
Critical
How does the drug interact with Onitraz Capsule:
The blood level of Cisapride may be significantly raised by combining Cisapride with Onitraz Capsule.

How to manage the interaction:
Despite the possibility of an interaction when cisapride and Onitraz Capsule are combined, they can be taken if a doctor prescribes them. Consult a doctor if you develop any side symptoms, such as fainting, lightheadedness, dizziness, or rapid or pounding heartbeats. Without consulting a doctor, never stop taking any medication. Note: Cisapride is no longer available in the market.
ItraconazoleSilodosin
Critical
How does the drug interact with Onitraz Capsule:
Coadministration of Onitraz Capsule with Silodosin can increase the blood levels and effects of Silodosin, which may lead to side effects including extremely low blood pressure and increased heart rate.

How to manage the interaction:
Taking Onitraz Capsule with Silodosin together is not recommended as it can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, headache, flushing, nasal congestion, or heart palpitation. Do not discontinue any medications without consulting a doctor.
ItraconazoleColchicine
Critical
How does the drug interact with Onitraz Capsule:
Coadministration of colchicine with Onitraz Capsule may increase the blood levels of colchicine, increasing the risk of serious side effects.

How to manage the interaction:
Colchicine with Onitraz Capsule can be taken if prescribed by a doctor, despite the possibility of an interaction. However, contact a doctor if you experience abdominal pain, nausea, vomiting, diarrhea, fever, muscle pain, weakness, fatigue, and/or numbness or tingling in your hands and feet. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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ITRACONAZOLE-100MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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ITRACONAZOLE-100MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Consuming Grapefruit, Grapefruit juice with Onitraz Capsule may impair the absorption of Onitraz Capsule, resulting in decreased antifungal effects. Avoid consuming Grapefruit and grapefruit juice with Onitraz Capsule.

Diet & Lifestyle Advise

  • Regularly change your socks and wash your feet. Avoid shoes that make your feet sweaty and hot.
  • In wet places such as changing rooms and gym showers, don’t walk on barefoot to prevent fungal infections.
  • Do not scratch the affected area of skin as it can spread the infection to other body parts.
  • Avoid sharing towels, combs, bedsheets, shoes or socks with others.
  • Wash your bed sheets and towels regularly.

Habit Forming

No

Therapeutic Class

ANTIFUNGALS

Onitraz Capsule Substitute

Substitutes safety advice
  • Canditral 100 Capsule 10's

    by Others

    14.09per tablet
  • Syntran 100 Capsule 10's

    by Others

    14.09per tablet
  • Itralase 100 Capsule 15's

    by AYUR

    15.63per tablet
  • Itaspor Capsule 10's

    by Others

    15.53per tablet
  • Alcros 100 Capsule 10's

    by AYUR

    16.74per tablet

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

You are not recommended to take Onitraz Capsule with simvastatin as co-administration of these two medicines may cause muscle weakness, unexplained muscle pain or tenderness, dark coloured urine, fever or flu symptoms. However, please consult a doctor before using Onitraz Capsule with other medicines.

No, Onitraz Capsule is not recommended for use during pregnancy as it may cause harm to the fetus. Also, it is advised to use effective contraceptive measures while taking Onitraz Capsule and after 2 months of stopping treatment with Onitraz Capsule. However, please inform your doctor if you are pregnant, planning for pregnancy or breastfeeding before taking Onitraz Capsule.

Onitraz Capsule may cause temporary or permanent hearing loss in some people. It is not necessary for everyone taking Onitraz Capsule to experience this adverse effect. However, if you notice any changes in hearing, stop taking Onitraz Capsule and consult a doctor immediately.

You are advised to take antacids (drugs used to reduce acid in the stomach) such as omeprazole, pantoprazole and esomeprazole at least 1 hour before or 2 hours after taking Onitraz Capsule as co-administration of these medicines at the same time may reduce the effectiveness of Onitraz Capsule because antacids decrease the absorption and blood levels of Onitraz Capsule. However, please consult a doctor before taking other medicines with Onitraz Capsule.

Yes, fungal infection is a contagious skin condition which spreads from one person to another through direct skin to skin contact or by contact with contaminated soil or surfaces and infected animals. Therefore, it is recommended to avoid close direct contact until the infection is clear and avoid sharing things with the infected person as it can also spread the infection.

You are not recommended to stop taking Onitraz Capsule without consulting your doctor as it may cause recurring infection. Therefore, take Onitraz Capsule for as long as your doctor has prescribed it, and if you experience any difficulty while taking Onitraz Capsule, please consult your doctor.

Drug-Drug Interactions Checker List

  • ESOMEPRAZOLE
  • OMEPRAZOLE
  • PANTOPRAZOLE
  • FLUTICASONE
  • BUDESONIDE
  • HYDROCODONE
  • WARFARIN
  • SIMVASTATIN
  • TERFENADINE
  • ALPRAZOLAM

Special Advise

  • Regular blood tests are recommended before and while taking Onitraz Capsule to monitor liver functioning especially if you have any liver problems.

Disease/Condition Glossary

Fungal infection: It is a skin disease in which a fungus attacks the tissue and cause infection. It may be contagious (spread from one person to another). The symptoms of a fungal infection include blisters, itching, redness, scaling and swelling of the skin. Yeast infection is caused by a type of fungus called candida and commonly occurs in moist and warm areas of the body. It is not contagious. It may cause infections in the mouth (oral thrush), vagina, nails, groin or armpits.

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