Oxaliage 100 mg Injection 50 ml

Written By Santoshini Reddy G , M Pharmacy

Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

MRP ₹5840

(Inclusive of all Taxes)

₹876.0 Cashback (15%)

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Whats That

About Oxaliage 100 mg Injection 50 ml

Oxaliage 100 mg Injection 50 ml belongs to the group of medicines called platinum-containing antineoplastic agents used alone or in combination with other anti-cancer medicines to treat cancer of the large bowel/intestine (advanced colon or colorectal cancer).

Oxaliage 100 mg Injection 50 ml contains Oxaliplatin, which works by killing the cancer cells. Thereby, it helps treat cancer.

In some cases, Oxaliage 100 mg Injection 50 ml may cause side effects such as mild nausea, vomiting, diarrhoea, fever, and headache. Most of these side effects may not require medical attention and resolve gradually over time. Do not be reluctant to talk with your doctor if any of the side effects persist or worsen.

Do not use Oxaliage 100 mg Injection 50 ml if you are breastfeeding. Consult a doctor immediately if you become pregnant during treatment with Oxaliage 100 mg Injection 50 ml. This medicine is not recommended for children as safety and effectiveness have not been established. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

Uses of Oxaliage 100 mg Injection 50 ml

Colon and rectal cancer

Directions for Use

Oxaliage 100 mg Injection 50 ml will be administered by a qualified physician; do not self-administer.

Medicinal Benefits

Oxaliage 100 mg Injection 50 ml contains Oxaliplatin, which belongs to the group of medicines called platinum-containing antineoplastic agents used to treat stage III colon cancer after complete removal of the primary tumour and metastatic cancer of the colon and rectum. It is used in combination with other anti-cancer medicines, such as 5-fluorouracil and folinic acid. Oxaliage 100 mg Injection 50 ml works by killing the cancer cells. Thereby, it helps treat cancer. Oxaliage 100 mg Injection 50 ml may also be used with other medicines to prevent colon cancer from spreading in patients who have had surgery to remove the tumour.

Storage

Keep Oxaliage 100 mg Injection 50 ml out of reach and sight of children.

Side effects of Oxaliage 100 mg Injection 50 ml

Increased Risk Of Infection Due To Low Neutrophil Count

Talk to your doctor about medicines to manage neutropenia based on the underlying cause.
Avoid contact with people who are sick.
Wash your hands regularly with soap and water.
Avoid unpasteurized dairy products.

Low Platelet Count

Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
If you experience severe bleeding or bruising, seek emergency medical attention immediately.

Anemia

Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
Consume vitamin C-rich foods as they aid iron absorption.
Limit tea, cocoa, and coffee as these can slow iron absorption.
Exercise regularly; however, do not overdo it.

Nausea

Overcome Medication-Induced Nausea: A 9-Step Plan

Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
Divide your daily food intake into smaller, more frequent meals to reduce nausea.
Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
Use ginger (tea, ale, or candies) to help relieve nausea.
Get adequate rest and also avoid strenuous activities that can worsen nausea.
Talk to your doctor about taking anti-nausea medication if your nausea is severe.
Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Loose And Watery Stools

Here are the precise steps to cope with diarrhoea caused by medication usage:

Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Burning Or Tingling Sensation

Change positions or take a break from activity to relieve symptoms.
Avoid postures that put a lot of pressure on just one area of the body.
If you have vitamin deficiency, take supplements or change your diet.
Exercise regularly like cycling, walking or swimming.
Avoid sitting with your legs crossed.
Clench and unclench your fists and wiggle your toes.
Massage the affected area.

Drug Warnings

Do not use Oxaliage 100 mg Injection 50 ml if you are allergic to any of its components, if you are breastfeeding, have a low blood cell count, have severe kidney problems, tingling and numbness in the fingers/toes, and have difficulty performing fragile tasks, such as buttoning clothes. Inform the doctor if you ever suffered an allergic reaction to platinum-containing medicines, have mild/moderate kidney problems, liver problems or abnormal liver function tests during therapy, or heart disorders like prolongation of the QT interval (abnormal electrical signal), an irregular heartbeat, or a family history of heart problems. Seek immediate medical attention if you experience symptoms of an allergic reaction (rash, itching, hives, reddening of the skin, hoarseness, difficulty breathing or swallowing, feeling as if your throat is closing, dizziness, swelling of the lips and tongue, lightheadedness, or fainting), unpleasant sensation in the throat, rhabdomyolysis (muscle pain and swelling), nerve problems (sensitivity to cold temperature or cold objects, pain, tingling or burning sensation), Posterior Reversible Encephalopathy Syndrome (headache, confusion, seizures, vision problems), myelosuppression (chills or shivering, burning or pain on urination, pain on swallowing, sore throat, cough with mucus, persistent diarrhoea), lung problems (shortness of breath, wheezing, cough), or bleeding problems (vomit that looks like coffee grounds or bloody vomit, pink or brown urine, weakness, dizziness, changes in speech, confusion, unexplained bleeding or dark-coloured/tarry stools).

Drug-Drug Interactions

OxaliplatinZiprasidone

Critical

OxaliplatinDisopyramide

Severe

Drug-Drug Interactions

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OxaliplatinZiprasidone

Critical

How does the drug interact with Oxaliage 100 mg Injection 50 ml:
Combining Oxaliage 100 mg Injection 50 ml with Ziprasidone can increase the risk of QTc prolongation.

How to manage the interaction:
Taking Oxaliage 100 mg Injection 50 ml with Ziprasidone is not recommended, please consult your doctor before taking it.

OxaliplatinDisopyramide

Severe

How does the drug interact with Oxaliage 100 mg Injection 50 ml:
The combined use of Oxaliage 100 mg Injection 50 ml and Disopyramide can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Oxaliage 100 mg Injection 50 ml and Disopyramide can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.

OxaliplatinMifepristone

Severe

How does the drug interact with Oxaliage 100 mg Injection 50 ml:
Co-administration of Oxaliage 100 mg Injection 50 ml with mifepristone can increase the risk of irregular heart rhythms.

How to manage the interaction:
Taking Oxaliage 100 mg Injection 50 ml with mifepristone together is avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not discontinue any medications without consulting a doctor.

OxaliplatinMoxifloxacin

Severe

How does the drug interact with Oxaliage 100 mg Injection 50 ml:
Using Moxifloxacin together with Oxaliage 100 mg Injection 50 ml can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction between Oxaliage 100 mg Injection 50 ml and Moxifloxacin, you can take these medicines together if prescribed by a doctor. However, consult the doctor immediately if you experience dizziness, shortness of breath, or heart palpitations (irregular heartbeat). Do not stop using any medications without a doctor's advice.

OxaliplatinTofacitinib

Severe

How does the drug interact with Oxaliage 100 mg Injection 50 ml:
Taking Tofacitinib with Oxaliage 100 mg Injection 50 ml may increase the risk of infection.

How to manage the interaction:
Although taking Oxaliage 100 mg Injection 50 ml and Tofacitinib together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without talking to your doctor.

OxaliplatinEfavirenz

Severe

How does the drug interact with Oxaliage 100 mg Injection 50 ml:
Taking Oxaliage 100 mg Injection 50 ml with Efavirenz can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Oxaliage 100 mg Injection 50 ml with Efavirenz together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

OxaliplatinEtanercept

Severe

How does the drug interact with Oxaliage 100 mg Injection 50 ml:
When Etanercept is used with Oxaliage 100 mg Injection 50 ml, the likelihood or severity of infection may increase.

How to manage the interaction:
Although there is a possible interaction between Oxaliage 100 mg Injection 50 ml and Etanercept, you can take these medicines together if prescribed by a doctor. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.

OxaliplatinBaricitinib

Severe

How does the drug interact with Oxaliage 100 mg Injection 50 ml:
Coadministration of baricitinib and Oxaliage 100 mg Injection 50 ml can raise the risk of developing serious infections.

How to manage the interaction:
Although there is an interaction, baricitinib can be taken with Oxaliage 100 mg Injection 50 ml if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without talking to a doctor.

OxaliplatinChloroquine

Severe

How does the drug interact with Oxaliage 100 mg Injection 50 ml:
Using chloroquine together with Oxaliage 100 mg Injection 50 ml can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking chloroquine and Oxaliage 100 mg Injection 50 ml together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.

OxaliplatinClozapine

Severe

How does the drug interact with Oxaliage 100 mg Injection 50 ml:
Co-administration of Oxaliage 100 mg Injection 50 ml with Clozapine can increase the risk of neutropenia (low white blood count).

How to manage the interaction:
Although taking Oxaliage 100 mg Injection 50 ml and Clozapine together can evidently cause an interaction, it can be taken if a doctor has suggested it. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Eat a healthy diet and exercise regularly to maintain proper weight.
Avoid smoking and alcohol consumption.
Include vegetables and fruits in your diet.
Avoid fast food, fried food, processed meats, refined carbs and added sugar.
Get optimal sleep; rest well.
Drink enough water and eat fibre-rich foods, vegetables and fruits.

Side Effects of Oxaliage 100 mg Injection 50 ml

Mild nausea
Vomiting
Diarrhoea
Headache
Peripheral neuropathy
Fatigue
Back pain
Stomach pain

Habit Forming

No

Therapeutic Class

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Author Details

Written By

Santoshini Reddy G

M Pharmacy

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 8, 2025 | 9:50 AM IST

We provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

How does Oxaliage 100 mg Injection 50 ml work?

Oxaliage 100 mg Injection 50 ml works by killing the cancer cells. Thereby, it helps treat cancer.

Does Oxaliage 100 mg Injection 50 ml affect fertility?

Oxaliage 100 mg Injection 50 ml may have an anti-fertility effect, which could be irreversible. Therefore, male patients should seek medical advice on the conservation of sperm prior to treatment with Oxaliage 100 mg Injection 50 ml.

Is it safe to eat or drink cold items?

Avoid drinking or eating anything colder than room temperature. Do not touch any cold objects, wash your hands in cold water, go near air conditioners or freezers, or go outside in cold weather unless absolutely necessary for five days after you receive each dose of Oxaliage 100 mg Injection 50 ml. Wear a hat, gloves, and a scarf, and cover your mouth and nose if you must go outside in cold weather.

Does Oxaliage 100 mg Injection 50 ml decrease the ability to fight infections?

Oxaliage 100 mg Injection 50 ml may decrease the ability to fight infections due to reduced white blood cells. Stay away from sick people during treatment with Oxaliage 100 mg Injection 50 ml.

Special Advise

Women must use reliable contraception during treatment and for nine months after receiving the last dose.
Male patients are advised not to father a child during treatment and for six months after the last dose. Use effective contraception during this time.
If you are due to undergo any surgery, including dental surgery, inform the doctor/dentist that you are on treatment with Oxaliage 100 mg Injection 50 ml.
Avoid eating or drinking anything that is colder than room temperature for five days after receiving each dose of Oxaliage 100 mg Injection 50 ml. To reduce side effects caused by cold temperature-cover yourself with a blanket while getting treatment with Oxaliage 100 mg Injection 50 ml, wear warm clothing in cold weather at all times, cover your mouth and nose with a scarf and wear gloves whilst touching cold objects. Drink fluid at room/warm temperature and always drink through a straw. Avoid using ice and AC, touching cold metals, and breathing deeply when exposed to cold air.

Disease/Condition Glossary

Colon and rectal cancer: It is a cancer of the colon or rectum. Colorectal cancer is the growth of cells that form in the lower end of the digestive tract. Most of these cancers begin as polyps (non-cancerous growths). Symptoms may include abdominal discomfort, blood in the stool, and changes in bowel habits like constipation or diarrhoea.