apollo
0
Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

Online payment accepted

rxMedicinePrescription drug

Whats That

tooltip

Composition

PALONOSETRON

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About Palonosar Injection 1's

Palonosar Injection 1's belongs to a class of drugs called antiemetics used to prevent nausea and vomiting during chemotherapy. Nausea is a feeling of uneasiness of the stomach that often comes before vomiting. On the other hand, vomiting is the forcible voluntary or involuntary emptying of stomach contents through the mouth.

Palonosar Injection 1's contains Palonosetron which works by blocking the action of serotonin, a chemical that stimulates the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, it prevents nausea and vomiting.

Palonosar Injection 1's will be administered by a healthcare professional; do not self-administer. In some cases, you may experience diarrhoea, constipation, dizziness or headache. Most of these side effects of Palonosar Injection 1's do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Palonosar Injection 1's or any other medicines, please tell your doctor. Palonosar Injection 1's may be given to children above 1 month in doses as advised by a doctor based on the child's body weight. If you are pregnant or breastfeeding, please inform your doctor before taking Palonosar Injection 1's. Drive only if you are alert as Palonosar Injection 1's may cause tiredness or dizziness. You are recommended to avoid heavy meals and take small nourishing snacks throughout the day. Drink plenty of water to avoid dehydration.

Uses of Palonosar Injection 1's

Nausea and vomiting

Directions for Use

Palonosar Injection 1's will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Palonosar Injection 1's contains Palonosetron which blocks the action of serotonin, a chemical that stimulates the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, it prevents nausea and vomiting during chemotherapy.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Palonosar Injection 1's

  • Diarrhoea
  • Constipation
  • Dizziness
  • Headache

Drug Warnings

If you are allergic to Palonosar Injection 1's or any other medicines, please tell your doctor. Palonosar Injection 1's may be given to children above 1 month in doses as advised by a doctor based on the child's body weight. If you are pregnant or breastfeeding, please inform your doctor before taking Palonosar Injection 1's. Drive only if you are alert as Palonosar Injection 1's may cause tiredness or dizziness. You are recommended to avoid heavy meals and take small nourishing snacks throughout the day. Drink plenty of water to avoid dehydration.

Drug-Drug Interactions

verifiedApollotooltip
PalonosetronZiprasidone
Critical
PalonosetronClomipramine
Severe

Drug-Drug Interactions

Login/Sign Up

PalonosetronZiprasidone
Critical
How does the drug interact with Palonosar Injection:
Combining Palonosar Injection with Ziprasidone can increase the risk of side effects.

How to manage the interaction:
Taking Ziprasidone with Palonosar Injection is not recommended, please consult your doctor before taking it.
PalonosetronClomipramine
Severe
How does the drug interact with Palonosar Injection:
The combined use of Palonosar Injection with clomipramine can increase the risk of serotonin syndrome (Serotonin syndrome is a condition in which a chemical called serotonin builds up in your body, causing signs and symptoms ranging from mild (shivering and diarrhea) to severe (muscle rigidity, fever, and seizures)).

How to manage the interaction:
Although taking clomipramine and Palonosar Injection together can cause an interaction, it can be taken if your doctor has suggested it. However, if you have sudden dizziness, lightheadedness, fainting, confusion, hallucination, fits, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles, or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea, or fast or rapid heartbeats during therapy, consult the doctor.
PalonosetronPentazocine
Severe
How does the drug interact with Palonosar Injection:
Taking Palonosar Injection with Pentazocine may increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although there is a possible interaction between Pentazocine and Palonosar Injection, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
PalonosetronParoxetine
Severe
How does the drug interact with Palonosar Injection:
Using Palonosar Injection together with paroxetine can increase the risk of condition called the serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Paroxetine with Palonosar Injection together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these symptoms like confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramps, nausea, vomiting, diarrhea, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
PalonosetronDextromethorphan
Severe
How does the drug interact with Palonosar Injection:
Co-administration of Dextromethorphan and Palonosar Injection may increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Although there is a possible interaction between Dextromethorphan and Palonosar Injection, you can take these medicines together if prescribed by a doctor. However, if you experience symptoms such as seizures (fits), extreme changes in blood pressure, confusion, hallucination, increased heart rate, fever, excessive sweating, shivering or shaking, tremors, incoordination, blurred vision, muscle spasms or stiffness, nausea, vomiting, stomach cramp, and diarrhea, contact a doctor immediately. Do not discontinue the medication without consulting a doctor.
PalonosetronCeritinib
Severe
How does the drug interact with Palonosar Injection:
Taking Ceritinib with Palonosar Injection can increase the risk of an irregular heart rhythm and other side effects.

How to manage the interaction:
Although taking Ceritinib and Palonosar Injection together can evidently cause an interaction, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
PalonosetronFentanyl
Severe
How does the drug interact with Palonosar Injection:
Taking fentanyl with Palonosar Injection may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although taking Fentanyl with Palonosar Injection can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience confusion, hallucinations (seeing and hearing things that do not exist), increased heart rate, fever, excessive sweating, muscle pain or stiffness, stomach cramps, vomiting, or diarrhoea, consult a doctor. Do not discontinue any medications without consulting your doctor.
PalonosetronVilazodone
Severe
How does the drug interact with Palonosar Injection:
When Vilazodone is taken with Palonosar Injection, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
There may be a possibility of interaction between Vilazodone and Palonosar Injection, but it can be taken if prescribed by a doctor. If you notice any of these signs - like confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea-call a doctor right away. Do not stop using any medications without a doctor's advice.
PalonosetronLinezolid
Severe
How does the drug interact with Palonosar Injection:
When linezolid is taken with Palonosar Injection it can cause serotonin syndrome. (a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of linezolid along with Palonosar Injection can lead to an interaction, it can be taken if recommended by a doctor. However, if you experience symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, incoordination, stomach pain, nausea, vomiting, and diarrhea, consult the doctor. Do not discontinue any medications without consulting a doctor.
PalonosetronAmiodarone
Severe
How does the drug interact with Palonosar Injection:
Coadministration of Amiodarone with Palonosar Injection can lead to or increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Amiodarone with Palonosar Injection together is avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Login/Sign Up

Diet & Lifestyle Advise

  • Eat a healthy diet and a low-fat diet, especially in small portions, as it will be easy for digestion. Avoid eating over-sweet food and include more salty food, especially if you have been vomiting.
  • Also, if you like to vomit at a specific time, avoid eating your favourite food at that particular time as your taste for that food may get turned off.
  • Drink any other liquid at least 30 minutes after eating food.
  • If the smell of food makes you feel sick (vomit), do not cook food as it may worsen your condition. Let someone else do the cooking or use prepared food from the freezer.

Habit Forming

No

Therapeutic Class

ANTIEMETICS

Author Details

Doctor imageWe provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

Login/Sign Up

Drug-Drug Interactions Checker List

  • CITALOPRAM
  • FLUVOXAMINE
  • PAROXETINE
  • SERTRALINE
  • ESCITALOPRAM
  • DULOXETINE
  • VENLAFAXINE
  • QUINIDINE
  • AMIODARONE
  • NICARDIPINE
  • MOXIFLOXACIN
  • ERYTHROMYCIN
  • DOMPERIDONE
  • THIORIDAZINE
  • QUETIAPINE
  • CHLORPROMAZINE
  • HALOPERIDOL

Disease/Condition Glossary

Nausea and vomiting: Nausea is a feeling of uneasiness of the stomach that often comes before vomiting. On the other hand, vomiting is the forcible voluntary or involuntary emptying of stomach contents through the mouth. In short, nausea and vomiting are not diseases but are symptoms of many conditions like infections, motion sickness, an early stage of pregnancy, and gastroparesis (slow stomach emptying). There is a receptor located in our brain known as the chemoreceptor zone (CTZ) that controls vomiting.

whatsapp Floating Button