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Written By Veda Maddala , M Pharmacy
Reviewed By Hari Kumar , MBBS
Non returnable*
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Composition :

PALONOSETRON-0.50MG

Manufacturer/Marketer :

Ajanta Pharma Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About PALOZAC 0.50MG TABLET

PALOZAC 0.50MG TABLET belongs to a class of drugs called antiemetics used to prevent nausea and vomiting during chemotherapy. Nausea is a feeling of uneasiness of the stomach that often comes before vomiting. On the other hand, vomiting is the forcible voluntary or involuntary emptying of stomach contents through the mouth.

PALOZAC 0.50MG TABLET contains Palonosetron which works by blocking the action of serotonin, a chemical that stimulates the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, it prevents nausea and vomiting.

Take PALOZAC 0.50MG TABLET as prescribed by your doctor. You are advised to take PALOZAC 0.50MG TABLET for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience diarrhoea, constipation, dizziness or headache. Most of these side effects of PALOZAC 0.50MG TABLET do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to PALOZAC 0.50MG TABLET or any other medicines, please tell your doctor. PALOZAC 0.50MG TABLET is not recommended for children. If you are pregnant or breastfeeding, please inform your doctor before taking PALOZAC 0.50MG TABLET. Drive only if you are alert as PALOZAC 0.50MG TABLET may cause tiredness or dizziness. You are recommended to avoid heavy meals and take small nourishing snacks throughout the day. Drink plenty of water to avoid dehydration.

Uses of PALOZAC 0.50MG TABLET

Nausea and vomiting

Directions for Use

Tablet/Capsule: Swallow it as a whole with a glass of water. Do not crush, chew or break it.Tablet MD: Place the tablet in your mouth and do not swallow it. Allow it to melt completely. Do not handle the tablet with wet hands.

Medicinal Benefits

PALOZAC 0.50MG TABLET contains Palonosetron that blocks the action of serotonin, a chemical that stimulates the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, it prevents nausea and vomiting during chemotherapy.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

If you are allergic to PALOZAC 0.50MG TABLET or any other medicines, please tell your doctor. The oral form is not recommended for children. However, the injection may be given to children above 1 month as advised by a doctor. If you are pregnant or breastfeeding, please inform your doctor before taking PALOZAC 0.50MG TABLET. Drive only if you are alert as PALOZAC 0.50MG TABLET may cause tiredness or dizziness. You are recommended to avoid heavy meals and take small nourishing snacks throughout the day. Drink plenty of water to avoid dehydration.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Palozac 0.50mg Tablet:
Combining Palozac 0.50mg Tablet with Ziprasidone can increase the risk of side effects.

How to manage the interaction:
Taking Ziprasidone with Palozac 0.50mg Tablet is not recommended, please consult your doctor before taking it.
How does the drug interact with Palozac 0.50mg Tablet:
Taking fentanyl with Palozac 0.50mg Tablet may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although taking Fentanyl with Palozac 0.50mg Tablet can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience confusion, hallucinations (seeing and hearing things that do not exist), increased heart rate, fever, excessive sweating, muscle pain or stiffness, stomach cramps, vomiting, or diarrhoea, consult a doctor. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Palozac 0.50mg Tablet:
Combining Palozac 0.50mg Tablet with Amitriptyline can increase the risk of serotonin syndrome.(A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Although using Palozac 0.50mg Tablet and Amitriptyline together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Inform a doctor if you have recently taken amitriptyline. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Palozac 0.50mg Tablet:
Co-administration of Dextromethorphan and Palozac 0.50mg Tablet may increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Although there is a possible interaction between Dextromethorphan and Palozac 0.50mg Tablet, you can take these medicines together if prescribed by a doctor. However, if you experience symptoms such as seizures (fits), extreme changes in blood pressure, confusion, hallucination, increased heart rate, fever, excessive sweating, shivering or shaking, tremors, incoordination, blurred vision, muscle spasms or stiffness, nausea, vomiting, stomach cramp, and diarrhea, contact a doctor immediately. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Palozac 0.50mg Tablet:
The combined use of Palozac 0.50mg Tablet with clomipramine can increase the risk of serotonin syndrome (Serotonin syndrome is a condition in which a chemical called serotonin builds up in your body, causing signs and symptoms ranging from mild (shivering and diarrhea) to severe (muscle rigidity, fever, and seizures)).

How to manage the interaction:
Although taking clomipramine and Palozac 0.50mg Tablet together can cause an interaction, it can be taken if your doctor has suggested it. However, if you have sudden dizziness, lightheadedness, fainting, confusion, hallucination, fits, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles, or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea, or fast or rapid heartbeats during therapy, consult the doctor.
How does the drug interact with Palozac 0.50mg Tablet:
When Vilazodone is taken with Palozac 0.50mg Tablet, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
There may be a possibility of interaction between Vilazodone and Palozac 0.50mg Tablet, but it can be taken if prescribed by a doctor. If you notice any of these signs - like confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea-call a doctor right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with Palozac 0.50mg Tablet:
Using Buspirone together with Fenfluramine can increase the risk of a serious condition called serotonin syndrome (A condition resulting from the accumulation of high levels of serotonin in the body. Serotonin is a chemical that plays a role in overall wellbeing and especially a mood stabilizer).

How to manage the interaction:
Co- administration of buspirone along with Palozac 0.50mg Tablet can lead to an interaction, it can be taken if recommended by a doctor. However, if you experience symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, incoordination, stomach pain, nausea, vomiting, and diarrhea, consult the doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Palozac 0.50mg Tablet:
When linezolid is taken with Palozac 0.50mg Tablet it can cause serotonin syndrome. (a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of linezolid along with Palozac 0.50mg Tablet can lead to an interaction, it can be taken if recommended by a doctor. However, if you experience symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, incoordination, stomach pain, nausea, vomiting, and diarrhea, consult the doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Palozac 0.50mg Tablet:
Taking Palozac 0.50mg Tablet with Pentazocine may increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although there is a possible interaction between Pentazocine and Palozac 0.50mg Tablet, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Palozac 0.50mg Tablet:
The combined use of Palozac 0.50mg Tablet and Hydroxychloroquine can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of palponosetron and Hydroxychloroquine can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult the doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet and a low-fat diet, especially in small portions, as it will be easy for digestion. Avoid eating over sweet food and include more salty food, especially if you have been vomiting.
  • Also, if you like to vomit at a specific time, avoid eating your favourite food at that particular time as your taste for that food may get turned off.
  • Drink any other liquid at least 30 minutes after eating food.
  • If the smell of food makes you feel sick (vomit), do not cook food as it may worsen your condition. Let someone else do cooking or use prepared food from the freezer.

Habit Forming

No

Therapeutic Class

ANTIEMETICS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

PALOZAC 0.50MG TABLET contains Palonosetron that works by blocking the action of serotonin, a chemical that stimulates the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, it prevents nausea and vomiting.

You are not recommended to take erythromycin with PALOZAC 0.50MG TABLET as it may increase the risk of severe irregular heart rhythm. However, please consult your doctor before taking other medicines with PALOZAC 0.50MG TABLET.

PALOZAC 0.50MG TABLET may cause constipation as a side effect. It is not necessary for everyone taking PALOZAC 0.50MG TABLET to experience this side effect. However, if the condition persists or worsens, please consult a doctor.

PALOZAC 0.50MG TABLET should be used with caution in patients suffering from heart problems as it may worsen the condition. Therefore, inform your doctor if you have any heart problems before taking have PALOZAC 0.50MG TABLET so that the dose may be adjusted appropriately.

You are not recommended to stop taking PALOZAC 0.50MG TABLET without consulting your doctor as it may increase the risk of nausea and vomiting during chemotherapy. Therefore, take PALOZAC 0.50MG TABLET for as long as your doctor has prescribed it and if you experience any difficulty while taking PALOZAC 0.50MG TABLET, please consult your doctor.

Drug-Drug Interactions Checker List

  • CITALOPRAM
  • FLUOXETINE
  • FLUVOXAMINE
  • PAROXETINE
  • SERTRALINE
  • ESCITALOPRAM
  • DULOXETINE
  • VENLAFAXINE
  • QUINIDINE
  • AMIODARONE
  • NICARDIPINE
  • MOXIFLOXACIN
  • ERYTHROMYCIN
  • DOMPERIDONE
  • THIORIDAZINE
  • QUETIAPINE
  • CHLORPROMAZINE
  • HALOPERIDOL

Special Advise

Disease/Condition Glossary

Nausea and vomiting: Nausea is a feeling of uneasiness of the stomach that often comes before vomiting. On the other hand, vomiting is the forcible voluntary or involuntary emptying of stomach contents through the mouth. In short, nausea and vomiting are not diseases but are symptoms of many conditions like infections, motion sickness, an early stage of pregnancy, and gastroparesis (slow stomach emptying). There is a receptor located in our brain known as the chemoreceptor zone (CTZ) that controls vomiting.

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