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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Aug 20, 2024 | 12:53 PM IST

About Pentasa 1gm Enema 100 ml

Pentasa 1gm Enema 100 ml belongs to a class of anti-inflammatory drugs used to treat ulcerative colitis. Ulcerative colitis is a chronic inflammatory bowel disease that causes inflammation of the large intestine lining (colon). It produces ulcers on the colon's lining, which may cause bleeding and discharge of pus and mucus. Ulcerative proctitis is a condition in which ulcerative colitis solely affects the rear channel (rectum). Pentasa 1gm Enema 100 ml used for the treatment of ulcerative proctitis and is exclusively designed for rectal usage.

Pentasa 1gm Enema 100 ml contains Mesalazine, which works by inhibiting the production of certain chemical substances, such as prostaglandins, that cause pain and swelling. Thus, it helps reduce inflammation (redness and swelling) in the intestines and provides relief from symptoms such as stomach pain or bleeding.

Use Pentasa 1gm Enema 100 ml as directed by your physician. Sometimes, you may experience diarrhoea, stomach pain, headache or nausea. Most of these side effects of Pentasa 1gm Enema 100 ml do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Inform your doctor if you are allergic to Mesalazine, aspirin,  or other medicines. Pentasa 1gm Enema 100 ml should be used with caution in the elderly. If pregnant or breastfeeding, please inform your doctor before using the Pentasa 1gm Enema 100 ml. Avoid taking Pentasa 1gm Enema 100 ml if you have severe kidney failure. Avoid taking Pentasa 1gm Enema 100 ml if you have blood abnormalities or kidney problems caused by other medicines such as Sulphasalazine.

Non returnable*
COD available

Online payment accepted

Prescription drug

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Non returnable*
COD available

Online payment accepted

Composition

MESALAZINE-1GM

Consume Type

RECTAL

Return Policy

3 Days Returnable

Expires on or after

Apr-24

for this medicine

Uses of Pentasa 1gm Enema 100 ml

Ulcerative colitis, Ulcerative proctitis

Medicinal Benefits

Pentasa 1gm Enema 100 ml contains Mesalazine, an anti-inflammatory drug used to treat ulcerative colitis, ulcerative proctitis and Crohn’s disease. It works by inhibiting the production of certain chemical substances, such as prostaglandins, that cause pain and swelling. Thereby helping reduce inflammation (redness and swelling) in the intestines and providing relief from symptoms such as stomach pain or bleeding. Also, Pentasa 1gm Enema 100 ml may prevent further episodes of ulcerative colitis. It is especially useful when ulcerative colitis symptoms affect the rectum.

Side Effects of Pentasa 1gm Enema 100 ml

  • Diarrhoea
  • Stomach pain
  • Headache
  • Nausea

Directions for Use

Suppository: Empty your bowels if required. Wash your hands thoroughly before and after use. Lie down on your left side and raise your right knee to the chest. Remove the wrapper and insert the pointed end of the suppository into the rectum. If necessary, grease the suppository tip with petroleum jelly.Enema: Use it as advised by the doctor. Shake the bottle well and remove the protective shield from the tip. Lie down on your left side, raise your right knee to the chest, or kneel and lean forward so that the head and chest are resting comfortably. Insert the enema bottle into the rectum with the tip pointing towards the navel. Squeeze the bottle gently until it is empty. Remove the bottle from the rectum and wash your hands thoroughly.Rectal foam: Pentasa 1gm Enema 100 ml should be used as directed by your doctor. It is exclusively intended for rectal usage. Before using, empty your bowels (if necessary) and wash your hands. Shake the bottle vigorously for at least 30 seconds. Remove the applicator's protective cap and hold the bottle by its top end. Lie on your left side, your left leg extended and your right leg bent. Insert the applicator (lubricant-coated) for easier entry into the rectum. Squeeze the bottle gently while holding it directed towards your navel. When the bottle is empty, remove the applicator from the rectum. Allow the drug to spread throughout the lower section of the large intestine for at least 30 minutes by remaining in this posture. Wash your hands (after usage) and wait till the next morning to empty your bowels. Your doctor will choose the appropriate amount and duration for you based on your age, body weight, and medical state.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Please tell your doctor if you are allergic to Mesalazine, aspirin, or sulfasalazine. Pentasa 1gm Enema 100 ml should be used with caution in the elderly. If you are pregnant or breastfeeding, please inform your doctor before using the Pentasa 1gm Enema 100 ml. Avoid taking Pentasa 1gm Enema 100 ml if you have severe kidney failure. Avoid taking Pentasa 1gm Enema 100 ml if you have had blood abnormalities or kidney problems while taking other medicines such as Sulphasalazine. Use Pentasa 1gm Enema 100 ml in dose and duration as advised by a doctor only. Do not swallow Pentasa 1gm Enema 100 ml. In case of accidental swallowing, drink plenty of water and consult a doctor immediately.

Therapeutic Class

ANTI- INFLAMMATORY AGENTS

Drug-Drug Interactions Checker List

  • ASPIRIN
  • IBUPROFEN
  • AZATHIOPRINE

Diet & Lifestyle Advise

  • Maintain a low-fat diet and eat foods rich in vitamin C, such as bell peppers, spinach, parsley and berries, which help in healing faster.
  • Opt for food and drinks high in Omega 3 fatty acids to get relief from pain, swelling, and inflammation. Omega 3 fatty acid-enriched foods include flaxseeds, walnut, soybean oil, salmon, and tuna if you prefer non-veg.
  • Eat more fibre-rich foods such as fruits and vegetables.
  • Eat smaller meals all day.
  • Drink small amounts of water throughout the day.
  • If you are intolerant to lactose, lower your intake of milk.
  • Avoid intake of foods high in sugar and fat and processed foods, as these may cause inflammation.
  • Try to avoid alcohol as it can affect your stomach and intestine and also limits the absorption of the important nutrients required by your body.

Habit Forming

No

Author Details

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Disease/Condition Glossary

Ulcerative colitis: It is a type of chronic inflammatory bowel disease that causes inflammation of the lining of the large intestine (colon) and produces ulcers on the lining of the colon, which may cause bleeding and discharge of pus and mucus. The common symptoms include bloody stools, stomach pain, rectal pain, diarrhoea, fever or weight loss. Additionally, it may cause other problems such as joint pain or swelling, mouth sores, skin problems, decreased appetite or nausea. The factors involved in causing ulcerative colitis include immune disorders and environmental factors like viruses, bacteria or antigens, which may trigger the immune system and genes inherited from the parent. 

Ulcerative proctitis: It is a condition in which ulcerative colitis solely affects the rear channel (rectum). 

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