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Reviewed By Hari Kumar , MBBS
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Consume Type

ORAL

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Not Returnable

Expires on or after

Apr-24

for this medicine

About Perindosyl-4Mg Tablet 10'S

Perindosyl-4Mg Tablet 10'S is an anti-hypertensive medication primarily used to treat high blood pressure and heart failure. It is also used to reduce the risk of cardiac events like a heart attack in patients with coronary artery disease and who have had a heart attack and/or surgery to improve the blood supply to the heart. Hypertension (High blood pressure) is a condition in which the force exerted by the blood against the artery walls becomes so high that it causes health problems, such as heart disease.

Perindosyl-4Mg Tablet 10'S contains Perindopril erbumine, an angiotensin-converting enzyme (ACE) inhibitor; it reduces increased blood pressure by blocking a naturally occurring substance known as angiotensin II (that tightens your blood vessels). Perindosyl-4Mg Tablet 10'S relaxes and widens the blood vessels, thereby lowering the blood pressure and making it easier for the heart to pump blood throughout the body. 

Take Perindosyl-4Mg Tablet 10'S as prescribed. Your doctor will advise you on the dosage and duration based on your medical condition. In some cases, you may experience dizziness, headache, weakness, vomiting, and nausea. Most of these side effects of Perindosyl-4Mg Tablet 10'S do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking this medicine on your own, even if your blood pressure becomes normal; doing so may worsen your condition. Avoid taking Perindosyl-4Mg Tablet 10'S if you are pregnant or breastfeeding. Perindosyl-4Mg Tablet 10'S is not recommended for children below 18years. Perindosyl-4Mg Tablet 10'S may cause dizziness and weakness, so drive or operate machinery only if you are alert. Keep your doctor informed about your health condition and medications to rule out any interactions.

Uses of Perindosyl-4Mg Tablet 10'S

Hypertension, Heart failure, Prevention of heart attack

Directions for Use

Swallow Perindosyl-4Mg Tablet 10'S as a whole with water; do not crush or chew it.

Medicinal Benefits

Perindosyl-4Mg Tablet 10'S is used to treat high blood pressure and heart failure. Additionally, it is also used to reduce the risk of cardiac events like a heart attack in patients with coronary artery disease and who have had a heart attack and/or surgery to improve the blood supply to the heart. Perindosyl-4Mg Tablet 10'S contains Perindopril erbumine, an angiotensin-converting enzyme (ACE) inhibitor; it reduces increased blood pressure by blocking a naturally occurring substance known as angiotensin II (that tightens your blood vessels). Perindosyl-4Mg Tablet 10'S allows constricted blood vessels to relax and therefore helps lower high blood pressure.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Perindosyl-4Mg Tablet 10'S

  • Cough
  • Nausea
  • Dizziness
  • Headache 
  • Vision disturbances
  • Ankle swelling
  • Weakness
  • Vomiting

Drug Warnings

Do not take Perindosyl-4Mg Tablet 10'S if you are allergic to any of the contents, ACE inhibitors, if you are taking sacubitril, valsartan, or aliskiren. Inform your doctor if you have/had kidney problems, dialysis, heart problems, liver dysfunction, diabetes, dehydration, angioedema, collagen vascular disease, or primary aldosteronism. Consult your doctor if you develop signs of infection or jaundice. Avoid taking Perindosyl-4Mg Tablet 10'S if you are pregnant or breastfeeding. Perindosyl-4Mg Tablet 10'S is not recommended for children below 18years. Perindosyl-4Mg Tablet 10'S may cause dizziness and weakness, so drive or operate machinery only if you are alert. Keep your doctor informed about your health condition and medications to rule out any interactions.

Drug-Drug Interactions

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PerindoprilAliskiren
Critical
PerindoprilPotassium citrate
Severe

Drug-Drug Interactions

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PerindoprilAliskiren
Critical
How does the drug interact with Perindosyl-4Mg Tablet:
Combining Aliskiren with Perindosyl-4Mg Tablet can increase the risk of low blood pressure, high potassium levels, and kidney damage.

How to manage the interaction:
Taking Perindosyl-4Mg Tablet with Aliskiren is not recommended, but can be taken if prescribed by a doctor. However, if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
PerindoprilPotassium citrate
Severe
How does the drug interact with Perindosyl-4Mg Tablet:
Taking Potassium citrate with Perindosyl-4Mg Tablet can cause hyperkalemia(a high level of the electrolyte potassium in the blood) which can increase the risk of kidney problems and abnormal heart rhythm.

How to manage the interaction:
Taking Perindosyl-4Mg Tablet with Potassium citrate together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is essential to maintain proper fluid intake while taking these medications. It is advised to reduce the intake of potassium-rich foods. Do not discontinue any medications without a doctor's advice.
PerindoprilAmiloride
Severe
How does the drug interact with Perindosyl-4Mg Tablet:
Amiloride when taken with Perindosyl-4Mg Tablet may cause a hyperkalemia (high potassium levels in blood).

How to manage the interaction:
Although taking amiloride and Perindosyl-4Mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor if you experience symptoms including fatigue, disorientation, numbness or tingling, and irregular heartbeats. Do not discontinue any medications without a doctor's advice.
PerindoprilPotassium iodide
Severe
How does the drug interact with Perindosyl-4Mg Tablet:
Combining Potassium Iodide with Perindosyl-4Mg Tablet can cause hyperkalemia(high potassium levels in blood) which can increase the risk the risk of kidney problems and abnormal heart rhythm.

How to manage the interaction:
Taking Perindosyl-4Mg Tablet with Potassium iodide together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat contact your doctor immediately. Do not stop using any medications without a doctor's advice. Do not discontinue any medications without consulting your doctor.
PerindoprilMipomersen
Severe
How does the drug interact with Perindosyl-4Mg Tablet:
Using Perindosyl-4Mg Tablet together with mipomersen can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Perindosyl-4Mg Tablet with Mipomersen can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark urine, pale stools, and/or yellowing of the skin or eyes contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
PerindoprilSpironolactone
Severe
How does the drug interact with Perindosyl-4Mg Tablet:
Using Perindosyl-4Mg Tablet together with spironolactone may cause hyperkalemia (high potassium level in blood).

How to manage the interaction:
Although taking spironolactone and Perindosyl-4Mg Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as weakness, confusion, numbness or tingling, and uneven heartbeats. Do not stop using any medications without consulting doctor.
PerindoprilAzilsartan medoxomil
Severe
How does the drug interact with Perindosyl-4Mg Tablet:
Taking Azilsartan medoxomil with Perindosyl-4Mg Tablet can cause low blood pressure, kidney function impairment, or increased potassium levels.

How to manage the interaction:
Although taking Azilsartan medoxomil with Perindosyl-4Mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. Consult a doctor if you experience vomiting, weakness, tingling in your hands and feet, or palpitations. Do not discontinue any medications without consulting a doctor.
PerindoprilTriamterene
Severe
How does the drug interact with Perindosyl-4Mg Tablet:
Combining Triamterene with Perindosyl-4Mg Tablet can increase the risk of hyperkalemia.

How to manage the interaction:
Although taking Perindosyl-4Mg Tablet and Triamterene together can evidently cause an interaction, it can be taken if your doctor has suggested it. Do not discontinue any medications without first consulting your doctor.
PerindoprilValsartan
Severe
How does the drug interact with Perindosyl-4Mg Tablet:
Coadministration of Perindosyl-4Mg Tablet with Valsartan may increase the risk of side effects (low blood pressure, kidney function impairment, and hyperkalemia (high blood potassium).

How to manage the interaction:
Although taking Perindosyl-4Mg Tablet together with Valsartan may result in an interaction, they can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience symptoms such as nausea, vomiting, confusion, numbness, tingling in hands and feet, and irregular heartbeat, contact a doctor. Do not discontinue any medication without consulting a doctor.
PerindoprilLosartan
Severe
How does the drug interact with Perindosyl-4Mg Tablet:
Coadministration of Losartan with Perindosyl-4Mg Tablet can increase of kidney problems and irregular heart rhythm.

How to manage the interaction:
Taking Losartan with Perindosyl-4Mg Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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PERINDOPRIL ERBUMINE-4MGPotassium rich foods
Moderate

Drug-Food Interactions

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PERINDOPRIL ERBUMINE-4MGPotassium rich foods
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Sweet Potatoes, Tomatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt

How to manage the interaction:
Taking Perindosyl-4Mg Tablet with potassium-containing foods can increase the risk of hyperkalemia (high potassium levels in the blood). Avoid moderately high or high potassium dietary intake with Perindosyl-4Mg Tablet, as it can lead to an interaction.

Diet & Lifestyle Advise

  • Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week.
  • Opt for a diet rich in whole grains, fruits, vegetables, and low-fat dairy products.
  • Limit intake of sodium chloride (table salt) in your daily diet.
  • Quitting smoking is the best strategy to lower the risk of heart disease.
  • Avoid chronic stress as it can raise your blood pressure. Try to enjoy and spend time with your loved ones to cope with stress and practice mindfulness techniques.
  • Try to include heart-healthy omega 3 fatty acid containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil to lower your elevated blood pressure.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES AND ACE INHIBITORS

Perindosyl-4Mg Tablet 10'S Substitute

Substitutes safety advice
  • Coversyl 4 mg Tablet 10's

    by Others

    17.78per tablet

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • NITROGLYCERIN
  • ALISKIREN
  • LOSARTAN
  • CANDESARTAN
  • CAPTOPRIL
  • ENALAPRIL
  • PREGABALIN
  • HYDROCHLOROTHIAZIDE
  • FUROSEMIDE
  • BUMETANIDE
  • CHLORTHALIDONE
  • INDAPAMIDE
  • NAPROXEN
  • INDOMETHACIN
  • CELECOXIB
  • CODEINE
  • LITHIUM

Special Advise

  • Monitor your blood pressure daily and if there is too much fluctuation, then immediately contact your doctor.
  • Inform your doctor if you are due to undergo any surgery, LDL apheresis (removal of cholesterol from blood), or desensitisation treatment.
  • Regular kidney function, blood pressure, and electrolyte level monitoring are advised.

Disease/Condition Glossary

Hypertension: It is a chronic condition in which the blood exerts increased pressure on the artery walls. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. High blood pressure (hypertension) can cause chest pain (angina) and heart attack (when blood supply to the heart is blocked), brain damage (stroke), and kidney failure. High blood pressure can be diagnosed with the help of a blood pressure monitor or sphygmomanometer. Ideal blood pressure should be between 90/60 mm of Hg and 120/80 mm of Hg.

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