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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Sunny S , MBBS
Non returnable*
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Composition :

PIOGLITAZONE-15MG

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Pioglit 15 Tablet

Pioglit 15 Tablet is an anti-diabetic medicine belonging to the class of thiazolidinedione (TZD), also called 'glitazones', used to treat type 2 (non-insulin-dependent) diabetes mellitus. Type 2 diabetes is an illness where the body doesn't make enough insulin, or the insulin that it makes doesn't work properly. This is diabetes that usually develops in adulthood.

Pioglit 15 Tablet contains Pioglitazone which helps control the sugar level in your blood when you have type 2 diabetes by helping your body make better use of the insulin it produces. Your doctor will check whether Pioglitazone is working 3-6 months after you start taking it. 

Pioglit 15 Tablet should be taken with food or an empty stomach. However, it should be taken at the same time of the day each time for the best results. For better advice, your doctor will decide what dose should be taken, which can change quickly depending on your condition. The most common side effect of Pioglit 15 Tablet is upper respiratory tract infection, headache, sinusitis, myalgia (muscle pain), and pharyngitis. Most of these side effects of Pioglit 15 Tablet do not require medical attention and gradually resolve over time. Please consult your doctor if these side effects become troublesome.

Pioglit 15 Tablet should not be stopped even if you feel better without consulting your doctor as sugar levels change. If you stop taking Pioglit 15 Tablet suddenly, it may increase your sugar levels which could further increase the risk of eyesight loss (retinopathy), kidney damage (nephropathy) and nerve damage (neuropathy). Pioglit 15 Tablet should not be taken if you have type 1 diabetes mellitus, if you are hypersensitive (allergic) to Pioglit 15 Tablet or any of the other ingredients of Pioglit 15 Tablet , have heart failure or have had heart failure in the past, diabetic ketoacidosis (a complication of diabetes causing rapid weight loss, nausea or vomiting), severe kidney or liver disease, bladder cancer. Please inform your doctor if you have any heart disease, are or planning to get pregnant or breastfeeding. The safety and efficacy of Pioglit 15 Tablet in children under 18 years have not been established, so it should not be given to them.

Uses of Pioglit 15 Tablet

Type 2 diabetes mellitus

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Pioglit 15 Tablet is an antidiabetic drug (thiazolidinedione/glitazones) used along with a proper diet and exercise to control high blood sugar (hyperglycaemia) in patients with type 2 diabetes. Pioglit 15 Tablet works by helping to restore your body's appropriate response to insulin, thereby lowering your blood sugar.

Storage

Store in a cool and dry place away from sunlight
Side effects of Pioglit 15 Tablet
  • If you experience low blood sugar levels, inform your doctor. They will assess the severity and make recommendations for the next actions.
  • Your doctor will assess your symptoms, blood sugar levels, and overall health before recommending the best course of action, which may include treatment, lifestyle modifications, or prescription adjustments.
  • Follow your doctor's instructions carefully to manage the episode and adjust your treatment plan.
  • Make medication adjustments as recommended by your doctor to prevent future episodes.
  • Implement diet and lifestyle modifications as your doctor advises to manage low blood sugar levels.
  • Monitor your blood sugar levels closely for patterns and changes.
  • Track your progress by recording your blood sugar levels, food intake, and physical activity.
  • Seek further guidance from your doctor if symptoms persist or worsen so that your treatment plan can be revised.
  • Eat fiber-rich foods, fruits, and vegetables, and track your food intake to monitor calorie consumption.
  • Limit takeout and restaurant meals, and weigh yourself weekly to stay motivated.
  • Build balanced meals, allow yourself to enjoy treats in moderation, and prioritize sleep and stress management through exercise and relaxation techniques.
  • Reduce salt intake to minimize fluid buildup.
  • Use compression stockings, sleeves, or gloves.
  • Gently massage the affected area towards the heart.
  • Protect the swollen area from injury and keep it clean.
  • Use lotion or cream to keep the skin moisturized.
  • Heart failure needs immediate medical attention. To manage this effect, the doctor's instructions must be followed strictly.
  • Take care of change in your weight as there can be sudden changes.
  • Rest and refrain from physical activity, and restart after a few days.
  • Reduce your salt intake and control your diet with the help of a dietician.
  • Track your symptoms and keep your follow-up appointments to manage severe side effects.
  • Heart failure needs immediate medical attention. To manage this effect, the doctor's instructions must be followed strictly.
  • Take care of change in your weight as there can be sudden changes.
  • Rest and refrain from physical activity, and restart after a few days.
  • Reduce your salt intake and control your diet with the help of a dietician.
  • Track your symptoms and keep your follow-up appointments to manage severe side effects.
  • Chest pain may last for a while and needs immediate medical attention as it is a significant health issue to be attended to.
  • Take rest and refrain from doing physical activity for a while, and restart after a few days.
  • Try applying an ice pack to the strained area for at least 20 minutes thrice a day. Ice pack thus helps reduce inflammation.
  • Sit upright and maintain proper posture if there is persistent chest pain. • Use extra pillows to elevate your position and prop your chest up while sleeping.

Drug Warnings

Fluid retention (oedema) may occur and can lead to congestive heart failure so, a combination of use with insulin and use in heart failure may increase the risk in patients taking Pioglit 15 Tablet . You should not take Pioglit 15 Tablet if you have kidney disease, as measured by a blood test. Pioglit 15 Tablet , when used with or without insulin, $ name tends to lower the blood sugar level. So, the doctor may lower the dose of insulin. Increased fractures may be reported in some women taking Pioglit 15 Tablet . Patients with bladder cancer and macular oedema (fluid build-up in the macula part of the retina of the eye) should consult the doctor before using Pioglit 15 Tablet .

Drug-Drug Interactions

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PioglitazoneLomitapide
Severe

Drug-Drug Interactions

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How does the drug interact with Pioglit 15 Tablet:
Co-administration of Pioglit 15 Tablet with Gatifloxacin may sometimes affect blood glucose levels. Both high blood glucose and, less frequently, low blood glucose have been reported.

How to manage the interaction:
Although there is a possible interaction, Pioglit 15 Tablet can be taken with Gatifloxacin if prescribed by the doctor. Consult the prescriber if you experience symptoms such as nervousness, confusion, headache, dizziness, drowsiness, tremors, nausea, hunger, weakness, excessive sweating, rapid heartbeat, increased urination, increased thirst, and increased hunger. Maintaining blood glucose levels is advised. Do not discontinue any medications without a doctor's advice.
PioglitazoneLomitapide
Severe
How does the drug interact with Pioglit 15 Tablet:
Co-administration of Pioglit 15 Tablet and Lomitapide may increase the risk of liver damage.

How to manage the interaction:
Although taking Lomitapide and Pioglit 15 Tablet together can possibly result in an interaction, it can be taken if a doctor has prescribed it. However, if you have any of the following symptoms: fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, fatigue, lack of appetite, nausea, vomiting, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
PioglitazoneMipomersen
Severe
How does the drug interact with Pioglit 15 Tablet:
Co-administration of Mipomersen and Pioglit 15 Tablet may increase the risk of liver damage.

How to manage the interaction:
Although taking Pioglit 15 Tablet and Mipomersen together can possibly result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience symptoms such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, nausea, vomiting, dark urine, light stools, and skin or eye yellowing, decreased hunger, consult the doctor. Do not stop using any medications without talking to the doctor.
How does the drug interact with Pioglit 15 Tablet:
Co-administration of Ketoconazole and Pioglit 15 Tablet, can increase the risk of side effects.

How to manage the interaction:
Taking Ketoconazole with Pioglit 15 Tablet together can result in an interaction, it can be taken if a doctor has advised it. However, consult the doctor, if you experience any unusual symptoms. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Pioglit 15 Tablet:
Taking Pioglit 15 Tablet with Clopidogrel can increases the blood levels of Pioglit 15 Tablet, when these medicines are taken together, you may experience hypoglycemia (low blood sugar).

How to manage the interaction:
Taking Clopidogrel together with Pioglit 15 Tablet may lead to interaction, but it can be taken if prescribed by your doctor. Consult a doctor immediately if you experience headache, dizziness, drowsiness, nervousness, weakness, shaking, or sweating. Do not discontinue any medication without consulting the doctor.
How does the drug interact with Pioglit 15 Tablet:
When Pioglit 15 Tablet is taken with Gemfibrozil, the level of Pioglit 15 Tablet in the blood can go up. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Pioglit 15 Tablet with Gemfibrozil together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you experience visual abnormalities, excessive or quick weight gain, swelling in the ankles or legs, trouble breathing, unusual fatigue, chest discomfort or tightness, fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark coloured urine, light coloured stools, or yellowing of the skin or eyes, seek medical attention immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Pioglit 15 Tablet:
Co-administration of Pioglit 15 Tablet and Leflunomide may increase the risk of liver damage.

How to manage the interaction:
Although taking Pioglit 15 Tablet and Leflunomide together can possibly result in an interaction, it can be taken if a doctor has prescribed it. However, if you have any of the following symptoms: fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, fatigue, lack of appetite, nausea, vomiting, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Pioglit 15 Tablet:
Co-administration of Teriflunomide and Pioglit 15 Tablet may increase the risk of liver damage.

How to manage the interaction:
Although taking Pioglit 15 Tablet and Teriflunomide together can possibly result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience symptoms such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, nausea, vomiting, dark urine, light stools, and skin or eye yellowing, decreased hunger, consult the doctor. Do not stop using any medications without talking to the doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Fill your half plate with starchy veggies, a quarter with proteins, and a quarter with whole grain.
  • Eat at regular interval. Do not take the long gap between a meal or snack.
  • Monitor your blood sugar level regularly especially when there are a lot of fluctuations.
  • Invest at least 150 min of moderate-intensity physical activity and 15 minutes of high-intensity exercise every week.
  • Lose weight gradually to achieve a healthy body mass index (18.5 to 24.9).
  • Replace refined carbohydrates containing foods with whole grain foods and increase intake of fruits and veggies and other fibre enriched foods.
  • Reduce intake of saturated fat (or hidden fats) in the food like chips, crisps, pastries, biscuits and samosas. Choose omega 3 fatty acid-containing oils for daily cooking. For frying, you may use palm oil, mustard oil, groundnut oil, rice bran oil, and safflower oil.
  • Do not take stress as it may elevate your blood sugar level. You may adopt stress management techniques like mindfulness, yoga or meditation to control stress-related to blood sugar changes.
  • Opt for low-fat dairy products (low-fat yoghurt, fat-free milk and cheese etc.).
  • Keep your blood pressure as normal (120/80) as possible. As it reduces the risk of cardiovascular diseases in diabetes patients.

Habit Forming

No

Therapeutic Class

ANTIDIABETICS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Drug-Drug Interactions Checker List

  • GEMFIBROZIL
  • RIFAMPICIN

Special Advise

  • Keep taking the drug even if you think your blood sugar levels are under control. If you miss a dose, do not take a larger dose. Consult your treating physician for advice. 
  • Take short, frequent meals, and avoid prolonged fasting when taking this drug. Beware of symptoms of hypoglycaemia which include sweating, dizziness, palpitations, shivering, intense thirst, dry mouth, dry skin, frequent urination etc. Whenever you experience the symptoms mentioned above, immediately consume 5-6 candies, three glucose biscuits, or three teaspoons of honey/sugar and get in touch with your physician. Make sure to carry these with you at all times, especially for long travels. 
  • Before the doctor prescribes this medicine, it is always better that your physician knows about any underlying conditions like kidney or liver disease, prior heart attack, alcohol intake, etc.
  • Avoid drinking alcohol while on this drug as it increases the risk of hypoglycaemia (decrease in blood sugar which might be fatal in some cases) and lactic acidosis (when the lactic acid increases in the body, which impacts the functioning of various organs in the body).
  • Try to quit smoking and reduce your intake of carbohydrate-rich food like potatoes, rice, mangoes, bread, sugar etc.

Disease/Condition Glossary

Type 2 diabetes is a chronic or lifelong disease that keeps the body away from properly utilizing insulin. Hence, people affected with type 2 diabetes either do not produce enough insulin or resist insulin action. Middle-aged or older are most likely to suffer from type 2 diabetes, also known as adult-onset diabetes. Symptoms of type 2 diabetes include increased thirst, frequent urination at night, slow wound healing, increased hunger, fatigue, and blurred vision. There may be weight gain in some cases, while weight loss may be observed in rare cases. The complication of type 2 diabetes also includes neuropathy (nerve problems), nephropathy (kidney problems), and retinopathy (damaged retina of eyes or blindness), loss of limbs, sexual dysfunction, and increase the chance of heart attack or stroke.

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