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Written By Divya L , PharmaD
Reviewed By Sunny S , MBBS
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Manufacturer/Marketer :

Micro Labs Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Plagerine-A Capsule

Plagerine-A Capsule belongs to the class of antiplatelet drugs used for the prevention of heart attack and stroke. A heart attack occurs when a blood clot blocks the blood flow to the heart. This blockage of arteries is most often an accumulation of fat, cholesterol and other substances, which form a plaque in the arteries that feed the heart (coronary arteries). Signs of a heart attack include chest pain, upper body pain, sweating, nausea, fatigue and trouble breathing.

Plagerine-A Capsule is composed of two medicines, namely: Aspirin and Clopidogrel. These are blood thinners (anti-platelet) that prevent the formation of a clot in the blood vessels. Aspirin acts as a blood-thinning or anti-platelet agent in a low dose (about 75 mg) to prevent heart attack and stroke. Clopidogrel acts by preventing blood clots if you have severe chest pain (unstable angina or heart attack), stroke, and peripheral arterial disease (heart problem due to narrowed blood vessels). Plagerine-A Capsule helps in the free flow of blood, thereby preventing a heart attack, stroke, deep vein thrombosis (blood clot in the vein), and pulmonary embolism (blood clots in the arteries of lungs).

Your doctor will advise you on how often you take your tablets based on your medical condition. The common side effects of Plagerine-A Capsule include abdominal pain, indigestion, diarrhoea, easy bruising, and nosebleeds. Plagerine-A Capsule is known to cause dizziness and blurry vision, so driving should be avoided. Most of these side effects of Plagerine-A Capsule do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking this medicine of your own. Stopping Plagerine-A Capsule may worsen your condition and increase the risk of a future heart attack. Let your doctor know if are sensitive to clopidogrel or aspirin, have kidney/liver diseases, bleeding issues (like peptic ulcer, brain haemorrhage), pregnant or planning to become pregnant or breastfeeding. The patient should inform the doctor that they are taking Plagerine-A Capsule before any surgery is scheduled or any new medicine is taken. 

Uses of Plagerine-A Capsule

Prevention of heart attack and stroke.

Directions for Use

Tablet/capsule: Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Plagerine-A Capsule is composed of Aspirin and Clopidogrel, which act as blood thinners (anti-platelet) and prevent the formation of a clot in the blood vessels. Aspirin acts as a blood-thinning or anti-platelet agent in a low dose (about 75 mg) to prevent heart attack and stroke. Clopidogrel acts by preventing blood clots if you have severe chest pain (unstable angina or heart attack), stroke, and peripheral arterial disease (heart problem due to narrowed blood vessels). Plagerine-A Capsule helps in the free flow of blood, thereby preventing heart attack, stroke, deep vein thrombosis (blood clot in the vein), and pulmonary embolism (blood clots in the arteries of lungs).

Storage

Keep out of the sight and reach of children.

Drug Warnings

You should avoid taking Plagerine-A Capsule if you are allergic to Plagerine-A Capsule . Let your doctor know if you have a medical condition that is causing bleeding such as a haemophilia, stomach ulcer or bleeding within your head or bowel. Caution is required before giving Plagerine-A Capsule to the liver or kidney problems patients. People affected with respiratory problems like asthma, rhinitis or nasal polyps should consult a doctor before intake of Plagerine-A Capsule . Plagerine-A Capsule is not recommended for the breastfeeding mother as it passes into the breast milk. The safety and effectiveness of Plagerine-A Capsule in children less than 12 years of age have not been established. 

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Plagerine-A Capsule:
Combining Ketorolac tromethamine with Plagerine-A Capsule can increase the risk of adverse effects.

How to manage the interaction:
Taking Plagerine-A Capsule with Ketorolac tromethamine is not recommended, as it results in an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor’s advice.
How does the drug interact with Plagerine-A Capsule:
Co-administration of Ketorolac and Plagerine-A Capsule may increase the risk of side effects.

How to manage the interaction:
Taking Ketorolac with Plagerine-A Capsule is not recommended but can be taken together if prescribed by a doctor. However, consult a doctor if you experience unusual bleeding or bruising, dizziness, tarry stools, coughing up or vomiting fresh or dried blood, severe headache and weakness. Do not stop using any medications without talking to a doctor.
How does the drug interact with Plagerine-A Capsule:
When Selexipag and Plagerine-A Capsule are taken together, the body's ability to break down Selexipag may be reduced.

How to manage the interaction:
Taking Plagerine-A Capsule with Selexipag is not recommended, please consult your doctor before taking it. They can be taken if prescribed by your doctor.
How does the drug interact with Plagerine-A Capsule:
Taking Plagerine-A Capsule together with mifepristone increases the risk of vaginal bleeding in women.

How to manage the interaction:
Although taking Plagerine-A Capsule with mifepristone is not recommended, that would certainly result in interaction, it can be taken if a doctor prescribes it. If you experience prolonged and heavy bleeding, consult a doctor immediately. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Plagerine-A Capsule:
Taking fondaparinux with Plagerine-A Capsule can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Although there is an interaction between fondaparinux and Plagerine-A Capsule, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience bleeding, severe back pain, dizziness, black or red stools, severe headache, weakness, and vomiting. Do not stop using any medications without talking to a doctor.
How does the drug interact with Plagerine-A Capsule:
Using dabigatran with Plagerine-A Capsule, may enhance the risk of bleeding problems.

How to manage the interaction:
Although there is a possible interaction between Plagerine-A Capsule and dabigatran etexilate, you can take these medicines together if prescribed by a doctor. However, if you notice unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness while taking these drugs, inform a doctor immediately. Do not stop using any medications without consulting doctor.
How does the drug interact with Plagerine-A Capsule:
Coadministration of Plagerine-A Capsule with Acetazolamide may cause side effects.

How to manage the interaction:
Although there is a possible interaction between Plagerine-A Capsule and acetazolamide, you can take these medicines together if prescribed by a doctor. However, if you experience symptoms such as ringing in your ears, headache, nausea, vomiting, dizziness, confusion, hallucinations, or rapid breathing, fever, and seizure, please contact a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Plagerine-A Capsule:
Using Deferasirox together with Plagerine-A Capsule may increase your risk of developing gastrointestinal ulcers and bleeding.

How to manage the interaction:
Taking Plagerine-A Capsule with Deferasirox together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of hunger, and/or black, tarry stools, increased or decreased urination, fluid retention, swelling, breathing difficulty, muscle pains, tiredness, weakness, confusion, and abnormal heart rhythm, consult the doctor. If you experience diarrhea or vomiting while taking these medications, stay hydrated. Do not stop taking any medications without talking to a doctor.
How does the drug interact with Plagerine-A Capsule:
Coadministration of Brinzolamide with Plagerine-A Capsule may cause side effects.

How to manage the interaction:
Although there is a possible interaction between Plagerine-A Capsule and brinzolamide, you can take these medicines together if prescribed by a doctor. However, if you experience ringing in your ears, headache, vomiting, dizziness, or palpitations, please contact a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Plagerine-A Capsule:
Co-administration of Plagerine-A Capsule and Rivaroxaban can increase the risk of unusual bleeding.

How to manage the interaction:
Although Co-administration of Plagerine-A Capsule and Rivaroxaban can lead to an interaction, they can be taken together if advised by a doctor. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Take the medication as directed by the doctor and at regular intervals. Do not use other over-the-counter medications, herbal or vitamin supplements without informing your pharmacist or doctor when you take Plagerine-A Capsule .
  • Keep your cholesterol and triglyceride levels under control.
  • Eat at regular intervals, and maintain a healthy diet that includes fresh fruits, and vegetables.
  • Limit alcohol intake since it raises blood pressure and increases the risk of heart diseases.
  • Keep a check on your weight and exercise regularly to keep your heart healthy.
  • Your doctor also guides you on how to notice and manage the early symptoms of detecting heart diseases. 

Side Effects of Plagerine-A Capsule

  • Abdominal pain
  • Indigestion
  • Diarrhoea
  • Easy bruising
  • Nosebleeds
  • Increased bleeding tendency

Habit Forming

No

Therapeutic Class

PLATELET AGGREGATION INHIBITOR

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Plagerine-A Capsule consists Aspirin and Clopidogrel. Aspirin acts as a blood-thinning or anti-platelet agent in a low dose to prevent heart attack and stroke. Clopidogrel acts by preventing blood clots if you have severe chest pain (unstable angina or heart attack), stroke, and peripheral arterial disease (heart problem due to narrowed blood vessels).

Please consult your doctor if Plagerine-A Capsule needs to be discontinued before undergoing surgery. The doctor might ask you to stop taking Plagerine-A Capsule a few days before surgery since it can cause an increased risk of bleeding during surgery.

Plagerine-A Capsule consists of Aspirin and Clopidogrel. These are blood-thinning agents and can increase the risk of bleeding. It is advised to be cautious during your daily activities like shaving, cutting fingernails or using sharp objects. Also, please consult your doctor beforehand if you undergo any surgery.

Plagerine-A Capsule is generally safe to take for a long time. It works best if you take it for many months or even years. If you're at risk of getting a stomach ulcer, your doctor may prescribe a medicine to treat ulcer, while you're taking Plagerine-A Capsule .

Drug-Drug Interactions Checker List

  • WARFARIN
  • HEPARIN
  • FLUOXETINE
  • LITHIUM
  • GLIBENCLAMIDE
  • REPAGLINIDE
  • METHOTREXATE
  • VALPROATE
  • PHENYTOIN
  • IBUPROFEN
  • OMEPRAZOLE
  • FLUCONAZOLE
  • RITONAVIR
  • COBICISTAT
  • PROBENECID

Special Advise

Let your doctor know that you are using Plagerine-A Capsule if you have a scheduled surgery since this medicine may increase the risk of bleeding.

Disease/Condition Glossary

A blood clot is a clump or aggregation of blood that changes from a liquid to a gel-like state. Clotting is a natural process that prevents you from losing too much blood in an accident, trauma, surgery or cut. When a clot forms inside the veins, it won’t always dissolve on its own and can become even life-threatening situation.

Stroke: When our brain does not get sufficient oxygen and blood supply, it starts dying within a few minutes leading to a heart attack or stroke.

Heart attack: It occurs when a blood clot blocks the blood flow to the heart. This blockage of arteries is most often an accumulation of fat, cholesterol and other substances, which form a plaque in the arteries that feed the heart (coronary arteries). During a heart attack (myocardial infarction), the blood supply which nourishes the heart with oxygen is cut off. This causes the heart muscle to die. Signs of a heart attack include chest pain, upper body pain, sweating, nausea, fatigue and trouble breathing.

Have a query?

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Alcohol

Caution

Avoid consuming alcohol since it may worsen the side effects like dizziness and increased blood pressure.

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Pregnancy

Caution

Plagerine-A Capsule is not recommended to use during pregnancy since it may affect the foetus. Please consult your doctor if you are planning to become pregnant or already pregnant before starting Plagerine-A Capsule .

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Breast Feeding

Caution

There is limited data on how Plagerine-A Capsule affects breastfeeding. Please consult your doctor before starting Plagerine-A Capsule .

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Driving

Caution

Do not drive or operate machinery if you experience dizziness or drowsiness while using Plagerine-A Capsule . Plagerine-A Capsule can also sometimes cause blurry vision, hence avoid driving in such situations. Seek medical attention if the symptoms persist longer.

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Liver

Caution

Let your doctor know if you have any history of liver diseases or hepatic impairment. Your doctor will weigh the benefits and potential risks before prescribing Plagerine-A Capsule .

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases. Your doctor will weigh the benefits and potential risks before prescribing Plagerine-A Capsule .

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Children

Caution

Plagerine-A Capsule is not recommended for children below the age of 16 years. The safety and efficacy of Plagerine-A Capsule have not been established in children.

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